hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10760.1
Complex Portal: CPX-23264
Confidence: Medium High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
CRB3 | Protein crumbs homolog 3 | 5 | UniProt   NCBI |
RPH3A | Rabphilin-3A (Exophilin-1) | 5 | UniProt   NCBI |
PALS1 | Protein PALS1 (MAGUK p55 subfamily member 5) (Membrane protein, palmitoylated 5) (Protein associated with Lin-7 1) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9705677 | 6.81752388431e-05 | 0.666666666667 | CRB3 PALS1 | SARS-CoV-2 targets PDZ proteins in cell-cell junction |
  REAC:R-HSA-420029 | 0.000715513386354 | 0.666666666667 | CRB3 PALS1 | Tight junction interactions |
  REAC:R-HSA-421270 | 0.00673703034894 | 0.666666666667 | CRB3 PALS1 | Cell-cell junction organization |
  KEGG:04530 | 0.00727572841175 | 0.666666666667 | CRB3 PALS1 | Tight junction |
  WP:WP4239 | 0.00973561742608 | 0.666666666667 | CRB3 PALS1 | Epithelial to mesenchymal transition in colorectal cancer |
  REAC:R-HSA-446728 | 0.017372320015 | 0.666666666667 | CRB3 PALS1 | Cell junction organization |
  KEGG:05165 | 0.0324411425615 | 0.666666666667 | CRB3 PALS1 | Human papillomavirus infection |
  REAC:R-HSA-1500931 | 0.0356523169758 | 0.666666666667 | CRB3 PALS1 | Cell-Cell communication |
  HPA:0410563 | 0.0424050554332 | 0.333333333333 | PALS1 | retina; limiting membrane[High] |
  REAC:R-HSA-9692912 | 0.0498224659464 | 0.333333333333 | PALS1 | SARS-CoV-1 targets PDZ proteins in cell-cell junction |
  CORUM:461 | 0.0499402709677 | 0.333333333333 | PALS1 | MPP4-MPP5-CRB1 complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
---|---|---|---|---|---|
 CRB3 |  PALS1 | 0.999 |            |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 RPH3A |  PALS1 | 0.955 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 RPH3A |  CRB3 | 0.333 |            |          | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes