hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10771.1
Complex Portal: CPX-23081
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ZNF528 | Zinc finger protein 528 | 3 | UniProt NCBI |
| ZNF707 | Zinc finger protein 707 | 4 | UniProt NCBI |
| ZNF445 | Zinc finger protein 445 (ZFP445) (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15) | 5 | UniProt NCBI |
| ZNF92 | Zinc finger protein 92 (Zinc finger protein HTF12) | 4 | UniProt NCBI |
| ZNF169 | Zinc finger protein 169 | 5 | UniProt NCBI |
| ZNF324B | Zinc finger protein 324B | 3 | UniProt NCBI |
| ZNF316 | Zinc finger protein 316 | 3 | UniProt NCBI |
| ZNF45 | Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5) | 4 | UniProt NCBI |
| RBAK | RB-associated KRAB zinc finger protein (RB-associated KRAB repressor) (hRBaK) (Zinc finger protein 769) | 5 | UniProt NCBI |
| ZNF324 | Zinc finger protein 324A (Zinc finger protein ZF5128) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05168 | 1.77531146995e-12 | 0.9 | RBAK ZNF324 ZNF45 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | Herpes simplex virus 1 infection |
| GO:0003700 | 5.20070976785e-08 | 1.0 | RBAK ZNF445 ZNF324 ZNF45 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | DNA-binding transcription factor activity |
| GO:0140110 | 2.0665560784e-06 | 1.0 | RBAK ZNF445 ZNF324 ZNF45 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | transcription regulator activity |
| REAC:R-HSA-212436 | 5.45862368901e-06 | 0.8 | ZNF445 ZNF324 ZNF45 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | Generic Transcription Pathway |
| REAC:R-HSA-73857 | 1.29782281188e-05 | 0.8 | ZNF445 ZNF324 ZNF45 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 3.48228100394e-05 | 0.8 | ZNF445 ZNF324 ZNF45 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | Gene expression (Transcription) |
| GO:0043565 | 3.56434715953e-05 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | sequence-specific DNA binding |
| GO:0000981 | 0.000320444929836 | 0.8 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF528 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000977 | 0.000400620832028 | 0.8 | RBAK ZNF445 ZNF324 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO:0003677 | 0.000564882356288 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | DNA binding |
| GO:0000976 | 0.000786230163884 | 0.8 | RBAK ZNF445 ZNF324 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | transcription cis-regulatory region binding |
| GO:0001067 | 0.000792598743402 | 0.8 | RBAK ZNF445 ZNF324 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | transcription regulatory region nucleic acid binding |
| GO:1990837 | 0.00113866713504 | 0.8 | RBAK ZNF445 ZNF324 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | sequence-specific double-stranded DNA binding |
| GO:0003690 | 0.00204413009732 | 0.8 | RBAK ZNF445 ZNF324 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | double-stranded DNA binding |
| GO:0000978 | 0.00542563337991 | 0.7 | RBAK ZNF445 ZNF324 ZNF92 ZNF528 ZNF707 ZNF324B | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000987 | 0.00625747038975 | 0.7 | RBAK ZNF445 ZNF324 ZNF92 ZNF528 ZNF707 ZNF324B | cis-regulatory region sequence-specific DNA binding |
| GO:0006355 | 0.0260722421898 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | regulation of DNA-templated transcription |
| GO:2001141 | 0.0275042486783 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | regulation of RNA biosynthetic process |
| GO:0006351 | 0.0396319173816 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | DNA-templated transcription |
| GO:0032774 | 0.0435543173798 | 0.9 | RBAK ZNF445 ZNF324 ZNF316 ZNF92 ZNF324B ZNF169 ZNF707 ZNF528 | RNA biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF324 | ZNF324B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZNF316 | ZNF324B | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| RBAK | ZNF169 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF92 | ZNF169 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF169 | ZNF45 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF169 | ZNF445 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF528 | ZNF324B | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF92 | ZNF707 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF324 | RBAK | 0.989 | 0.152 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF707 | ZNF445 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF316 | ZNF707 | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF316 | ZNF169 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF92 | RBAK | 0.979 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF445 | ZNF324B | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBAK | ZNF707 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBAK | ZNF445 | 0.969 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RBAK | ZNF324B | 0.969 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF324 | ZNF316 | 0.964 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF324 | ZNF169 | 0.955 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RBAK | ZNF316 | 0.952 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF316 | ZNF445 | 0.932 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF324 | ZNF445 | 0.919 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF324 | ZNF707 | 0.918 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF92 | ZNF316 | 0.916 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF169 | ZNF707 | 0.902 | bioplex3_WMM WMM_only | ||
| ZNF92 | ZNF324 | 0.843 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF92 | ZNF45 | 0.804 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF92 | ZNF445 | 0.802 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF45 | ZNF707 | 0.768 | bioplex3_WMM WMM_only | ||
| RBAK | ZNF45 | 0.763 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF45 | ZNF445 | 0.755 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF92 | ZNF324B | 0.698 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF324 | ZNF45 | 0.65 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RBAK | ZNF528 | 0.607 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF316 | ZNF45 | 0.575 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF324 | ZNF528 | 0.304 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF316 | ZNF528 | 0.283 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF445 | ZNF528 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF92 | ZNF528 | 0.218 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF707 | ZNF528 | 0.21 | bioplex3_WMM WMM_only | ||
| ZNF707 | ZNF324B | 0.079 | bioplex3_WMM WMM_only |
Related Complexes