hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10786.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MMP15 | Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2) | 5 | UniProt NCBI |
| GOLGA2 | Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95) | 5 | UniProt NCBI |
| SLC30A6 | Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6) | 5 | UniProt NCBI |
| UBIAD1 | UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-) (EC 2.5.1.39) (Transitional epithelial response protein 1) | 5 | UniProt NCBI |
| BLZF1 | Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor) | 5 | UniProt NCBI |
| GORASP2 | Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) | 5 | UniProt NCBI |
| DNAI3 | Dynein axonemal intermediate chain 3 (Testis development protein NYD-SP29) (WD repeat-containing protein 63) | 5 | UniProt NCBI |
| TMED7 | Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27) | 5 | UniProt NCBI |
| SLC30A5 | Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) (ZnT-like transporter 1) (hZTL1) | 5 | UniProt NCBI |
| GORASP1 | Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-162658 | 1.90298236919e-08 | 0.4 | GOLGA2 GORASP1 GORASP2 BLZF1 | Golgi Cisternae Pericentriolar Stack Reorganization |
| CORUM:6212 | 3.07577115383e-05 | 0.2 | GOLGA2 GORASP1 | GM130-GRASP65 complex |
| GO:0000139 | 6.54350130803e-05 | 0.7 | UBIAD1 GORASP1 BLZF1 TMED7 GOLGA2 GORASP2 SLC30A5 | Golgi membrane |
| REAC:R-HSA-68875 | 0.000225524796323 | 0.4 | GOLGA2 GORASP1 GORASP2 BLZF1 | Mitotic Prophase |
| GO:0007030 | 0.000418447412602 | 0.5 | GOLGA2 GORASP1 GORASP2 TMED7 BLZF1 | Golgi organization |
| GO:0005801 | 0.000971743443131 | 0.4 | GOLGA2 GORASP1 GORASP2 BLZF1 | cis-Golgi network |
| GO:0005794 | 0.00240439645893 | 0.8 | UBIAD1 GORASP1 BLZF1 TMED7 GOLGA2 GORASP2 SLC30A5 SLC30A6 | Golgi apparatus |
| REAC:R-HSA-6807878 | 0.00769948216088 | 0.3 | GOLGA2 TMED7 GORASP1 | COPI-mediated anterograde transport |
| WP:WP3529 | 0.0144252840529 | 0.2 | SLC30A6 SLC30A5 | Zinc homeostasis |
| REAC:R-HSA-68886 | 0.0216363645858 | 0.4 | GOLGA2 GORASP1 GORASP2 BLZF1 | M Phase |
| REAC:R-HSA-199977 | 0.0252825613706 | 0.3 | GOLGA2 TMED7 GORASP1 | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 0.0436921850818 | 0.3 | GOLGA2 TMED7 GORASP1 | Transport to the Golgi and subsequent modification |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GORASP1 | GOLGA2 | 1.0 | 0.23 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| BLZF1 | GORASP2 | 1.0 | 0.074 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 gupta_WMM |
| TMED7 | GORASP2 | 0.998 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TMED7 | BLZF1 | 0.996 | 0.08 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| TMED7 | GORASP1 | 0.989 | 0.052 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC30A6 | GORASP2 | 0.986 | 0.188 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| SLC30A5 | SLC30A6 | 0.985 | 0.276 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| BLZF1 | GORASP1 | 0.984 | 0.094 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| UBIAD1 | SLC30A6 | 0.984 | 0.096 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| SLC30A6 | TMED7 | 0.983 | 0.1 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| TMED7 | GOLGA2 | 0.974 | 0.166 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DNAI3 | GORASP1 | 0.965 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GOLGA2 | GORASP2 | 0.964 | 0.334 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| UBIAD1 | GORASP2 | 0.962 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TMED7 | MMP15 | 0.96 | 0.0842569832402 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| MMP15 | GORASP2 | 0.96 | 0.062 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| GORASP1 | GORASP2 | 0.958 | 0.108 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SLC30A5 | TMED7 | 0.957 | 0.152 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| SLC30A6 | BLZF1 | 0.952 | 0.122 | hein_WMM bioplex3_WMM gupta_WMM WMM_only |
| SLC30A5 | GORASP2 | 0.947 | 0.092 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| SLC30A6 | GOLGA2 | 0.875 | 0.302 | hein_WMM bioplex3_WMM WMM_only |
| SLC30A5 | BLZF1 | 0.817 | 0.194 | bioplex3_WMM gupta_WMM WMM_only |
| UBIAD1 | BLZF1 | 0.795 | 0.054 | hein_WMM gupta_WMM WMM_only |
| MMP15 | GOLGA2 | 0.621 | 0.076 | bioplex3_WMM WMM_only |
| MMP15 | BLZF1 | 0.587 | 0.09 | bioplex3_WMM WMM_only |
| SLC30A6 | MMP15 | 0.548 | 0.076 | bioplex3_WMM WMM_only |
| SLC30A6 | GORASP1 | 0.463 | 0.11 | hein_WMM bioplex3_WMM WMM_only |
| BLZF1 | GOLGA2 | 0.395 | 0.132 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| UBIAD1 | SLC30A5 | 0.218 | 0.18 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| UBIAD1 | GORASP1 | 0.192 | 0.18 | hein_WMM WMM_only |
| TMED7 | DNAI3 | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | |
| BLZF1 | DNAI3 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC30A5 | GOLGA2 | 0.157 | 0.208 | bioplex3_WMM WMM_only |
| DNAI3 | GOLGA2 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | |
| DNAI3 | GORASP2 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC30A5 | MMP15 | 0.096 | 0.042 | bioplex3_WMM WMM_only |
| UBIAD1 | TMED7 | 0.049 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only |
| UBIAD1 | GOLGA2 | 0.048 | 0.168 | hein_WMM WMM_only |
| MMP15 | GORASP1 | 0.044 | 0.084 | bioplex3_WMM WMM_only |
| SLC30A5 | GORASP1 | 0.009 | 0.11 | bioplex3_WMM WMM_only |
Related Complexes