hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
MDM2	E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)	5	UniProt NCBI
SURF2	Surfeit locus protein 2 (Surf-2)	3	UniProt NCBI
PRDM15	PR domain zinc finger protein 15 (EC 2.1.1.-) (PR domain-containing protein 15) (Zinc finger protein 298)	5	UniProt NCBI
RPL11	Large ribosomal subunit protein uL5 (60S ribosomal protein L11) (CLL-associated antigen KW-12)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HP:0002669	0.0222019103471	0.5	MDM2 RPL11	Osteosarcoma
CORUM:5331	0.049938562206	0.25	MDM2	YY1-MDM2-p53 complex
CORUM:7180	0.049938562206	0.25	MDM2	p53-MDM2 complex
CORUM:7249	0.049938562206	0.25	MDM2	ERS1-MDM2 complex

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
RPL11	SURF2	1.0	0.162	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
PRDM15	RPL11	0.991	0.288		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
RPL11	MDM2	0.984		structurally_consistent (dimer)	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
MDM2	SURF2	0.958		mutually_exclusive (P62913)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
PRDM15	MDM2	0.196			bioplex_WMM bioplex3_WMM WMM_only
PRDM15	SURF2	0.119	0.062		bioplex3_WMM WMM_only