hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10806.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TBP | TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) | 5 | UniProt NCBI |
| TAF1A | TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A) | 5 | UniProt NCBI |
| TAF1C | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | 5 | UniProt NCBI |
| TAF1D | TATA box-binding protein-associated factor RNA polymerase I subunit D (RNA polymerase I-specific TBP-associated factor 41 kDa) (TAFI41) (TATA box-binding protein-associated factor 1D) (TBP-associated factor 1D) (Transcription initiation factor SL1/TIF-IB subunit D) | 5 | UniProt NCBI |
| TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) | 5 | UniProt NCBI |
| EPB41L4B | Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5727 | 9.60315000334e-13 | 0.666666666667 | TAF1B TAF1A TBP TAF1C | TBP-TAF complex |
| REAC:R-HSA-73863 | 3.36987384985e-11 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | RNA Polymerase I Transcription Termination |
| REAC:R-HSA-73762 | 3.03950682117e-10 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | RNA Polymerase I Transcription Initiation |
| REAC:R-HSA-427359 | 7.56508722512e-10 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | SIRT1 negatively regulates rRNA expression |
| REAC:R-HSA-5250924 | 4.17575726773e-09 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | B-WICH complex positively regulates rRNA expression |
| REAC:R-HSA-73772 | 4.45764769353e-09 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | RNA Polymerase I Promoter Escape |
| REAC:R-HSA-5250913 | 1.02710475482e-08 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-427413 | 1.08474508115e-08 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 1.27335011764e-08 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 1.34173286275e-08 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | RNA Polymerase I Promoter Clearance |
| REAC:R-HSA-73864 | 1.41302060093e-08 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | RNA Polymerase I Transcription |
| REAC:R-HSA-212165 | 2.25985858591e-07 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | Epigenetic regulation of gene expression |
| REAC:R-HSA-74160 | 0.00558415609329 | 0.833333333333 | TAF1B TAF1A TAF1D TBP TAF1C | Gene expression (Transcription) |
| GO:0001046 | 0.00949259421943 | 0.5 | TAF1B TBP TAF1C | core promoter sequence-specific DNA binding |
| CORUM:721 | 0.0499436884912 | 0.166666666667 | TBP | PU.1-TBP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TAF1A | TAF1C | 0.998 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1D | TAF1B | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TAF1A | TAF1B | 0.997 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1A | TAF1D | 0.997 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM | |
| TAF1C | TAF1B | 0.996 | 0.15 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1C | TAF1D | 0.995 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| TBP | TAF1D | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TAF1D | EPB41L4B | 0.974 | bioplex_WMM bioplex3_WMM WMM_only | |
| TAF1B | EPB41L4B | 0.951 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| TAF1A | EPB41L4B | 0.948 | 0.096 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
| TAF1C | EPB41L4B | 0.934 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| TBP | TAF1A | 0.848 | 0.218 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| TBP | TAF1B | 0.505 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only |
| TBP | TAF1C | 0.383 | 0.12 | bioplex_WMM bioplex3_WMM WMM_only |
| TBP | EPB41L4B | 0.259 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes