hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10808.1

Complex Portal: CPX-10978

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
PLEKHA7	Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)	5	UniProt NCBI
CDR2L	Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen)	5	UniProt NCBI
SMTNL2	Smoothelin-like protein 2	3	UniProt NCBI
PI4KB	Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII)	5	UniProt NCBI
TIAM1	Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)	5	UniProt NCBI
ARHGEF38	Rho guanine nucleotide exchange factor 38	4	UniProt NCBI
MAP3K3	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)	5	UniProt NCBI
YWHAQ	14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)	5	UniProt NCBI
GPSM3	G-protein-signaling modulator 3 (Activator of G-protein signaling 4) (G18.1b) (Protein G18)	5	UniProt NCBI
CERT1	Ceramide transfer protein (hCERT) (Collagen type IV alpha-3-binding protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11)	5	UniProt NCBI
DENND4A	C-myc promoter-binding protein (DENN domain-containing protein 4A)	5	UniProt NCBI
PACS2	Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein)	5	UniProt NCBI
SAMD4A	Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A)	5	UniProt NCBI
SRGAP1	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)	5	UniProt NCBI
TFEB	Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35)	5	UniProt NCBI
ANKRD55	Ankyrin repeat domain-containing protein 55	5	UniProt NCBI
CDC25B	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)	5	UniProt NCBI
IRS2	Insulin receptor substrate 2 (IRS-2)	5	UniProt NCBI
SPATA13	Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)	5	UniProt NCBI
PLEKHG5	Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720)	5	UniProt NCBI
SPIRE2	Protein spire homolog 2 (Spir-2)	5	UniProt NCBI
SASH1	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein)	5	UniProt NCBI
MARK1	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)	5	UniProt NCBI
SAMD4B	Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B)	5	UniProt NCBI
FOXO3	Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)	5	UniProt NCBI
DMTN	Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)	5	UniProt NCBI
HOMEZ	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper-containing factor)	5	UniProt NCBI
SYDE2	Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2)	4	UniProt NCBI
MARK3	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)	5	UniProt NCBI
LNP1	Leukemia NUP98 fusion partner 1	2	UniProt NCBI
PTOV1	Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2)	5	UniProt NCBI
MAP2K5	Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)	5	UniProt NCBI
BRAF	Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)	5	UniProt NCBI
PTPN3	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)	5	UniProt NCBI
KIAA0930	Uncharacterized protein KIAA0930	3	UniProt NCBI
YWHAB	14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]	5	UniProt NCBI
PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]	5	UniProt NCBI
CLASP1	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)	5	UniProt NCBI
SFN	14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)	5	UniProt NCBI
SPIRE1	Protein spire homolog 1 (Spir-1)	5	UniProt NCBI
FAM53B	Protein FAM53B (Protein simplet)	5	UniProt NCBI
BAD	Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)	5	UniProt NCBI
YWHAE	14-3-3 protein epsilon (14-3-3E)	5	UniProt NCBI
YWHAH	14-3-3 protein eta (Protein AS1)	5	UniProt NCBI
MAP3K2	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)	5	UniProt NCBI
YWHAZ	14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)	5	UniProt NCBI
HDAC5	Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)	5	UniProt NCBI
CRTC1	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)	5	UniProt NCBI
FOXO1	Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)	5	UniProt NCBI
HDAC4	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	5	UniProt NCBI
FOXO4	Forkhead box protein O4 (Fork head domain transcription factor AFX1)	5	UniProt NCBI
YWHAG	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]	5	UniProt NCBI
SRGAP2	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)	5	UniProt NCBI
A0A1X9RU27		None	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9614399	2.27122885874e-18	0.18	SFN YWHAG YWHAB YWHAZ FOXO3 YWHAQ FOXO4 A0A1X9RU27 FOXO1	Regulation of localization of FOXO transcription factors
REAC:R-HSA-111447	2.2867240525e-14	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ SFN BAD YWHAQ	Activation of BAD and translocation to mitochondria
CORUM:5199	3.84147926912e-14	0.16	YWHAH MAP3K3 YWHAB YWHAZ YWHAG YWHAQ MAP2K5 YWHAE	Kinase maturation complex 1
REAC:R-HSA-9755779	9.60932546439e-13	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-2 targets host intracellular signalling and regulatory pathways
REAC:R-HSA-75035	2.07665744398e-12	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
REAC:R-HSA-9735871	7.74739646422e-12	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-1 targets host intracellular signalling and regulatory pathways
REAC:R-HSA-114452	2.00152068804e-11	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ SFN BAD YWHAQ	Activation of BH3-only proteins
REAC:R-HSA-9614085	1.35152007203e-10	0.18	SFN YWHAG YWHAB YWHAZ FOXO3 YWHAQ FOXO4 A0A1X9RU27 FOXO1	FOXO-mediated transcription
REAC:R-HSA-109606	2.4324349571e-09	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ SFN BAD YWHAQ	Intrinsic Pathway for Apoptosis
WP:WP5376	5.75044695569e-09	0.12	YWHAH YWHAZ YWHAB YWHAG YWHAQ YWHAE	17p13 3 YWHAE copy number variation
REAC:R-HSA-162582	5.89550760843e-08	0.52	IRS2 SYDE2 YWHAZ YWHAG FOXO1 SRGAP1 CLASP1 FOXO4 MARK3 TIAM1 YWHAB SFN BAD HDAC5 ARHGEF38 HDAC4 MAP2K5 SRGAP2 YWHAE PLEKHG5 GPSM3 YWHAH FOXO3 YWHAQ SPATA13 A0A1X9RU27	Signal Transduction
KEGG:05203	8.24976202003e-07	0.18	HDAC4 YWHAH YWHAZ YWHAE YWHAB YWHAG BAD HDAC5 YWHAQ	Viral carcinogenesis
REAC:R-HSA-1445148	1.12996562738e-06	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Translocation of SLC2A4 (GLUT4) to the plasma membrane
REAC:R-HSA-5628897	2.95857077159e-06	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	TP53 Regulates Metabolic Genes
REAC:R-HSA-5625740	3.53068720463e-06	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	RHO GTPases activate PKNs
REAC:R-HSA-194315	5.11933758261e-06	0.28	SFN YWHAH CLASP1 SYDE2 SRGAP1 YWHAG YWHAB SRGAP2 YWHAZ TIAM1 YWHAQ PLEKHG5 SPATA13 YWHAE	Signaling by Rho GTPases
WP:WP4542	5.57624325241e-06	0.1	FOXO4 FOXO3 FOXO1 A0A1X9RU27 YWHAQ	Leukocyte intrinsic Hippo pathway functions
REAC:R-HSA-69473	5.84197808899e-06	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	G2/M DNA damage checkpoint
REAC:R-HSA-5674400	6.68641946031e-06	0.1	FOXO4 FOXO3 FOXO1 A0A1X9RU27 BAD	Constitutive Signaling by AKT1 E17K in Cancer
REAC:R-HSA-9716542	6.75693034692e-06	0.28	SFN YWHAH CLASP1 SYDE2 SRGAP1 YWHAG YWHAB SRGAP2 YWHAZ TIAM1 YWHAQ PLEKHG5 SPATA13 YWHAE	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
REAC:R-HSA-198693	8.70451376338e-06	0.08	FOXO4 FOXO3 A0A1X9RU27 FOXO1	AKT phosphorylates targets in the nucleus
REAC:R-HSA-9692914	9.32573378486e-06	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-1-host interactions
WP:WP536	1.27994331846e-05	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Calcium regulation in cardiac cells
WP:WP179	1.63042562021e-05	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Cell cycle
KEGG:05160	2.05152400171e-05	0.14	YWHAH YWHAZ YWHAE YWHAB YWHAG BAD YWHAQ	Hepatitis C
WP:WP2380	2.43903552753e-05	0.14	IRS2 FOXO3 MAP3K2 TIAM1 BAD CRTC1 MAP2K5	Brain derived neurotrophic factor BDNF signaling pathway
REAC:R-HSA-109581	2.90674793747e-05	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ SFN BAD YWHAQ	Apoptosis
WP:WP289	3.75396669423e-05	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Myometrial relaxation and contraction pathways
KEGG:04110	5.38365653075e-05	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Cell cycle
REAC:R-HSA-2219528	7.44434883472e-05	0.12	IRS2 FOXO4 FOXO3 FOXO1 A0A1X9RU27 BAD	PI3K/AKT Signaling in Cancer
REAC:R-HSA-5357801	9.65082888477e-05	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ SFN BAD YWHAQ	Programmed Cell Death
KEGG:04114	9.9008893148e-05	0.12	YWHAH YWHAZ YWHAB YWHAG YWHAQ YWHAE	Oocyte meiosis
GO:0005829	9.96649137868e-05	0.72	MARK3 CERT1 YWHAZ YWHAG FOXO1 SAMD4B HOMEZ CLASP1 FOXO4 IRS2 SAMD4A PLEKHA7 TIAM1 CRTC1 YWHAB SFN DMTN SYDE2 HDAC5 BAD HDAC4 PI4KB SRGAP1 SPIRE1 SRGAP2 SASH1 MAP3K2 PFKFB2 PLEKHG5 DENND4A MAP3K3 YWHAH FOXO3 YWHAQ SPATA13 YWHAE	cytosol
REAC:R-HSA-9678108	0.000104889648112	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-1 Infection
REAC:R-HSA-5663202	0.000142068260218	0.2	HDAC4 MARK3 FOXO1 YWHAB HDAC5 FOXO3 BAD FOXO4 A0A1X9RU27 IRS2	Diseases of signal transduction by growth factor receptors and second messengers
REAC:R-HSA-195258	0.000213190805392	0.18	YWHAH SFN YWHAG YWHAB YWHAZ CLASP1 YWHAQ SRGAP2 YWHAE	RHO GTPase Effectors
WP:WP3915	0.000310293974791	0.12	IRS2 MAP3K2 FOXO3 FOXO1 MAP3K3 MAP2K5	Angiopoietin like protein 8 regulatory pathway
KEGG:04151	0.000367005310359	0.16	YWHAH YWHAG YWHAB YWHAE YWHAZ FOXO3 BAD YWHAQ	PI3K-Akt signaling pathway
REAC:R-HSA-69481	0.000370063200811	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	G2/M Checkpoints
WP:WP3844	0.000407161269592	0.08	FOXO4 FOXO3 BAD FOXO1	PI3K AKT mTOR signaling pathway and therapeutic opportunities in prostate cancer
WP:WP706	0.000439144624845	0.12	YWHAH YWHAZ YWHAB YWHAG YWHAQ YWHAE	Sudden infant death syndrome SIDS susceptibility pathways
REAC:R-HSA-204998	0.000485367904117	0.1	TIAM1 BAD ARHGEF38 YWHAE PLEKHG5	Cell death signalling via NRAGE, NRIF and NADE
REAC:R-HSA-9615017	0.00050489135655	0.08	FOXO4 FOXO3 A0A1X9RU27 FOXO1	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
KEGG:04390	0.0007095825478	0.12	YWHAH YWHAZ YWHAB YWHAG YWHAQ YWHAE	Hippo signaling pathway
REAC:R-HSA-9705683	0.00113266464006	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-2-host interactions
WP:WP481	0.00115272241494	0.12	IRS2 MAP3K2 FOXO3 FOXO1 MAP3K3 MAP2K5	Insulin signaling
GO:0050815	0.00125344998193	0.08	YWHAZ YWHAG YWHAB YWHAE	phosphoserine residue binding
REAC:R-HSA-69620	0.00148403520307	0.16	YWHAH SFN YWHAG YWHAB YWHAZ CLASP1 YWHAQ YWHAE	Cell Cycle Checkpoints
REAC:R-HSA-9617629	0.0015436485164	0.06	FOXO3 FOXO1 FOXO4	Regulation of FOXO transcriptional activity by acetylation
KEGG:04722	0.0016100159242	0.1	MAP3K3 YWHAE BAD MAP2K5 FOXO3	Neurotrophin signaling pathway
REAC:R-HSA-193704	0.00178757197848	0.1	TIAM1 BAD ARHGEF38 YWHAE PLEKHG5	p75 NTR receptor-mediated signalling
KEGG:04068	0.00290322341391	0.1	FOXO4 FOXO3 FOXO1 A0A1X9RU27 IRS2	FoxO signaling pathway
REAC:R-HSA-1257604	0.00425534546215	0.14	IRS2 A0A1X9RU27 FOXO3 FOXO1 FOXO4 HDAC5 BAD	PIP3 activates AKT signaling
REAC:R-HSA-193648	0.00470730835833	0.08	TIAM1 BAD ARHGEF38 PLEKHG5	NRAGE signals death through JNK
REAC:R-HSA-9614657	0.00710015550882	0.06	FOXO3 FOXO1 FOXO4	FOXO-mediated transcription of cell death genes
REAC:R-HSA-9617828	0.00710015550882	0.06	FOXO3 FOXO1 FOXO4	FOXO-mediated transcription of cell cycle genes
REAC:R-HSA-1643685	0.00710806985029	0.32	HDAC4 IRS2 SFN FOXO1 YWHAB YWHAE YWHAZ YWHAH FOXO3 YWHAG HDAC5 YWHAQ FOXO4 BAD A0A1X9RU27 MARK3	Disease
TF:M00800_1	0.0075092642461	0.58	YWHAH SYDE2 BAD FOXO1 SAMD4B IRS2 SAMD4A PLEKHA7 PTOV1 CRTC1 PACS2 FAM53B HDAC5 ARHGEF38 HDAC4 MAP3K2 CDR2L SRGAP2 SPIRE1 YWHAZ SASH1 SRGAP1 DENND4A MAP3K3 MARK3 A0A1X9RU27 FOXO3 YWHAQ SPIRE2	Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1
REAC:R-HSA-212436	0.00987236482155	0.26	HDAC4 YWHAH SFN FOXO1 YWHAB YWHAZ FOXO3 YWHAG HDAC5 YWHAE FOXO4 A0A1X9RU27 YWHAQ	Generic Transcription Pathway
REAC:R-HSA-9006925	0.0106055597874	0.14	IRS2 A0A1X9RU27 FOXO3 FOXO1 FOXO4 HDAC5 BAD	Intracellular signaling by second messengers
REAC:R-HSA-9694516	0.0128226348107	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	SARS-CoV-2 Infection
WP:WP437	0.0168138359262	0.1	FOXO4 MAP3K3 FOXO1 MAP3K2 MAP2K5	EGF EGFR signaling pathway
WP:WP2261	0.0178638341925	0.08	FOXO4 FOXO3 FOXO1 MAP2K5	Glioblastoma signaling pathways
REAC:R-HSA-73887	0.0246248577709	0.1	TIAM1 BAD ARHGEF38 YWHAE PLEKHG5	Death Receptor Signaling
REAC:R-HSA-73857	0.0308727090578	0.26	HDAC4 YWHAH SFN FOXO1 YWHAB YWHAZ FOXO3 YWHAG HDAC5 YWHAE FOXO4 A0A1X9RU27 YWHAQ	RNA Polymerase II Transcription
GO:0035556	0.0365345286996	0.4	SRGAP2 SYDE2 DENND4A PLEKHG5 SFN PI4KB BAD MARK3 DMTN YWHAE YWHAZ FOXO1 TIAM1 YWHAG SASH1 MAP3K2 MAP3K3 SPATA13 MAP2K5 MARK1	intracellular signal transduction
WP:WP3888	0.0391339996282	0.14	HDAC4 SPIRE1 FOXO4 FOXO3 FOXO1 HDAC5 YWHAE	VEGFA VEGFR2 signaling
KEGG:04152	0.0424359141788	0.08	FOXO3 FOXO1 IRS2 PFKFB2	AMPK signaling pathway
REAC:R-HSA-3700989	0.0490485895949	0.14	YWHAH YWHAG YWHAZ YWHAB SFN YWHAQ YWHAE	Transcriptional Regulation by TP53

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
YWHAZ	YWHAB	1.0	0.915
YWHAG	YWHAH	1.0	0.802
YWHAG	YWHAB	1.0	0.913
YWHAZ	YWHAH	1.0	0.724
YWHAH	YWHAB	1.0	0.77
YWHAG	YWHAE	1.0	0.782
YWHAH	YWHAE	1.0	0.534
YWHAZ	YWHAE	1.0	0.696
YWHAB	YWHAE	1.0	0.704
YWHAZ	YWHAG	1.0	0.864
YWHAQ	YWHAB	0.999	0.572	structurally_consistent (dimer)
YWHAH	SAMD4A	0.999	0.412630536131
SFN	SMTNL2	0.999		structurally_consistent (dimer)
YWHAZ	YWHAQ	0.999	0.662	structurally_consistent (dimer)
YWHAG	FAM53B	0.999
YWHAG	YWHAQ	0.999	0.77	structurally_consistent (dimer)
YWHAQ	YWHAH	0.999	0.526	structurally_consistent (dimer)
YWHAH	FAM53B	0.999
YWHAG	SAMD4A	0.999	0.708
YWHAQ	YWHAE	0.999	0.944	structurally_consistent (dimer)
SAMD4A	YWHAE	0.998	0.487119479865
FAM53B	YWHAB	0.998
YWHAG	SFN	0.998	0.644	structurally_consistent (dimer)
YWHAZ	SMTNL2	0.998
HDAC4	YWHAB	0.997	0.394
SMTNL2	YWHAH	0.997
YWHAZ	TFEB	0.997	0.622
SAMD4A	YWHAB	0.997	0.301325581395
SAMD4B	YWHAG	0.997	0.3265
HDAC4	YWHAH	0.997	0.39
YWHAQ	SFN	0.997	0.51	structurally_consistent (dimer)
SMTNL2	YWHAB	0.997		mutually_exclusive (P27348)
YWHAH	IRS2	0.996	0.44925
HDAC4	YWHAG	0.996	0.508
TFEB	YWHAE	0.996	0.426583333333
YWHAG	SMTNL2	0.996		mutually_exclusive (P27348)
YWHAH	MARK3	0.996	0.172
SAMD4B	YWHAE	0.996	0.224
SAMD4B	YWHAB	0.996	0.202722222222
YWHAG	IRS2	0.995	0.532
YWHAG	MARK3	0.995	0.202
YWHAQ	FAM53B	0.995
YWHAZ	SFN	0.995	0.732	structurally_consistent (dimer)
YWHAQ	SMTNL2	0.995		structurally_consistent (dimer)
MAP3K2	MAP2K5	0.995	0.192	structurally_consistent (dimer)
YWHAH	TFEB	0.995	0.340814070352
HDAC4	YWHAQ	0.995	0.394	structurally_consistent (dimer)
YWHAG	TFEB	0.995	0.578608695652
FAM53B	YWHAE	0.994
CLASP1	YWHAH	0.994	0.268
SFN	YWHAB	0.994	0.716	structurally_consistent (dimer)
MAP3K3	MAP2K5	0.994	0.082	structurally_consistent (dimer)
SMTNL2	YWHAE	0.993		mutually_exclusive (P27348)
YWHAG	MARK1	0.993	0.39
YWHAQ	MAP3K2	0.993	0.284	structurally_consistent (dimer)
YWHAH	BRAF	0.993	0.382
YWHAQ	TFEB	0.992	0.451702702703
YWHAG	MAP3K2	0.992	0.393416666667
MAP3K3	YWHAG	0.992	0.574538095238
TFEB	YWHAB	0.992	0.3775
MARK1	YWHAH	0.992	0.3034875
YWHAG	FOXO3	0.991	0.444
SFN	YWHAH	0.991	0.536	structurally_consistent (dimer)
BRAF	YWHAB	0.991	0.396
YWHAG	BRAF	0.991	0.482
PLEKHA7	YWHAG	0.991	0.5056
YWHAG	PFKFB2	0.991	0.31	mutually_exclusive (P27348)
MARK3	YWHAB	0.991	0.173041666667
PFKFB2	YWHAQ	0.991	0.374	structurally_consistent (dimer)
ANKRD55	YWHAQ	0.99
YWHAQ	BRAF	0.99	0.424	structurally_consistent (dimer)
CRTC1	YWHAG	0.99	0.37136
CDC25B	YWHAH	0.99	0.33
SFN	TFEB	0.99	0.337262626263
CDR2L	SFN	0.99	0.544
YWHAG	CDC25B	0.99	0.346
PFKFB2	YWHAB	0.99	0.314	mutually_exclusive (P27348)
SFN	BAD	0.989	0.136	structurally_consistent (dimer)
MAP3K3	YWHAQ	0.989	0.558
HDAC4	PTOV1	0.989	0.13
SFN	FAM53B	0.989
FOXO3	YWHAH	0.988	0.24
CDR2L	YWHAQ	0.988	0.554933333333
YWHAQ	DMTN	0.987	0.572	structurally_consistent (dimer)
YWHAZ	HDAC4	0.987	0.46747624264
SPATA13	YWHAB	0.987	0.237693851718
YWHAZ	BRAF	0.987	0.588666666667
IRS2	BRAF	0.987	0.11
YWHAG	TIAM1	0.986	0.534
YWHAQ	SAMD4A	0.986	0.533789595376
ANKRD55	YWHAB	0.986
MAP3K3	MAP3K2	0.986	0.16	mutually_exclusive (Q13163)
LNP1	YWHAE	0.986
SRGAP2	YWHAH	0.986	0.166
CDR2L	YWHAE	0.986	0.442315789474
YWHAG	DMTN	0.985	0.701020594966
YWHAZ	LNP1	0.985
PACS2	YWHAG	0.985	0.594
PFKFB2	YWHAH	0.985	0.332	mutually_exclusive (P27348)
MAP3K2	YWHAH	0.985	0.308090909091
YWHAG	BAD	0.985	0.508
SFN	YWHAE	0.984	0.643333333333	structurally_consistent (dimer)
YWHAH	LNP1	0.984
IRS2	YWHAE	0.984	0.460909090909
DMTN	YWHAE	0.984	0.189733333333
YWHAG	DENND4A	0.984	0.488	mutually_exclusive (P27348)
SRGAP2	YWHAG	0.984	0.454
CDR2L	YWHAB	0.984	0.430744186047
PI4KB	YWHAG	0.983	0.24
YWHAG	SPIRE1	0.983	0.3
PACS2	YWHAH	0.983	0.331910666153
IRS2	YWHAB	0.983	0.38679787234
CDC25B	YWHAB	0.983	0.38
YWHAZ	PFKFB2	0.983	0.498996309963	mutually_exclusive (P27348)
IRS2	PTOV1	0.983	0.098
PTOV1	YWHAB	0.982	0.30004
YWHAH	BAD	0.982	0.142
YWHAZ	GPSM3	0.982	0.314	mutually_exclusive (P27348)
PACS2	YWHAQ	0.982	0.6354
YWHAG	LNP1	0.982
YWHAZ	CDC25B	0.982	0.57
HDAC4	IRS2	0.981	0.140666666667
YWHAQ	LNP1	0.981
GPSM3	YWHAQ	0.981	0.506	structurally_consistent (dimer)
YWHAG	FOXO1	0.981	0.445171521036	mutually_exclusive (P27348)
YWHAH	KIAA0930	0.981	0.246666666667
YWHAQ	BAD	0.981	0.404	structurally_consistent (dimer)
CLASP1	YWHAB	0.98	0.282
SRGAP1	SRGAP2	0.98	0.202
LNP1	YWHAB	0.98
YWHAG	PTPN3	0.979	0.4224
BAD	YWHAB	0.979	0.12361779661
YWHAG	PTOV1	0.979	0.365892
SPIRE2	YWHAB	0.979
MARK1	YWHAQ	0.979	0.322	structurally_consistent (dimer)
YWHAQ	CDC25B	0.978	0.39	structurally_consistent (dimer)
YWHAZ	PLEKHG5	0.978
SFN	MAP3K2	0.978	0.304
SAMD4B	SAMD4A	0.978	0.068
YWHAZ	SPIRE1	0.977	0.294
YWHAQ	SPIRE1	0.977	0.276
YWHAQ	SPATA13	0.976	0.304
YWHAG	KIAA0930	0.976	0.325649224535
HDAC5	YWHAB	0.976	0.4	mutually_exclusive (P31947)
SRGAP1	YWHAG	0.976	0.49
SRGAP1	YWHAH	0.976	0.351043478261
MAP3K3	YWHAH	0.976	0.534956989247
YWHAQ	IRS2	0.976	0.488
PTPN3	YWHAB	0.975	0.36
BRAF	YWHAE	0.975	0.432
YWHAQ	PTPN3	0.975	0.580166666667
YWHAH	SPIRE1	0.975	0.222660377358
YWHAG	SPATA13	0.975	0.382862588235
YWHAH	DENND4A	0.975	0.28	mutually_exclusive (P27348)
SRGAP2	YWHAB	0.974	0.1955
SFN	KIAA0930	0.974	0.222	structurally_consistent (dimer)
DMTN	YWHAB	0.974	0.369648247322
YWHAZ	DMTN	0.974	0.451766666667
YWHAZ	SAMD4A	0.974	0.521171428571
SYDE2	YWHAB	0.974
SASH1	YWHAH	0.974	0.292
SPIRE1	YWHAB	0.973	0.204
YWHAH	FOXO1	0.973	0.432967741935	mutually_exclusive (P27348)
ARHGEF38	YWHAE	0.973
MAP3K3	SFN	0.973	0.387666666667
YWHAQ	MARK3	0.973	0.16
YWHAZ	MAP3K2	0.973	0.384619047619
MAP3K2	YWHAE	0.972	0.440862038381
FOXO1	YWHAB	0.972	0.465147618658	mutually_exclusive (P27348)
YWHAH	TIAM1	0.971	0.236
YWHAG	SASH1	0.971	0.498
CRTC1	YWHAH	0.971	0.153561845286	mutually_exclusive (P27348)
CDR2L	YWHAH	0.971	0.369797202797
YWHAH	SPATA13	0.971	0.252554778555
YWHAZ	CDR2L	0.97	0.574
YWHAH	PTOV1	0.97	0.388998934375
YWHAZ	BAD	0.97	0.0881428571429
YWHAQ	FOXO1	0.97	0.508	structurally_consistent (dimer)
HDAC4	YWHAE	0.969	0.564114834206
YWHAZ	ANKRD55	0.969
YWHAH	PTPN3	0.969	0.319
KIAA0930	YWHAB	0.969	0.24373134257
YWHAZ	KIAA0930	0.968	0.330909090909
CRTC1	YWHAB	0.967	0.15486779661
CERT1	MARK3	0.966	0.048
MARK1	YWHAB	0.966	0.268711538462
YWHAZ	FAM53B	0.966
DMTN	SFN	0.966	0.5104
YWHAZ	SPATA13	0.966	0.439017094017
CERT1	MARK1	0.965	0.076
YWHAG	SPIRE2	0.965
SYDE2	YWHAH	0.965
YWHAG	HDAC5	0.964	0.405777777778
SPIRE2	YWHAH	0.964
SFN	LNP1	0.964
YWHAZ	SAMD4B	0.964	0.196
SAMD4B	YWHAH	0.963	0.136
YWHAQ	PTOV1	0.963	0.364
GPSM3	YWHAB	0.963	0.266
HOMEZ	YWHAB	0.963	0.358	mutually_exclusive (P27348)
PI4KB	YWHAH	0.962	0.2315
ANKRD55	YWHAE	0.962
YWHAH	HDAC5	0.961	0.290709677419
PACS2	YWHAB	0.96	0.376
YWHAG	HOMEZ	0.959	0.630855106888	mutually_exclusive (P27348)
TIAM1	YWHAB	0.958	0.300446428571
SFN	BRAF	0.957	0.266
PLEKHA7	YWHAB	0.957	0.263648247322
DENND4A	YWHAB	0.957	0.314	mutually_exclusive (P27348)
CLASP1	ARHGEF38	0.957
PLEKHA7	YWHAH	0.957	0.194
YWHAQ	TIAM1	0.956	0.386
SRGAP1	YWHAB	0.955	0.304504885649
MAP3K3	YWHAZ	0.954	0.576
YWHAQ	FOXO4	0.954		mutually_exclusive (P31947)
YWHAZ	PI4KB	0.954	0.208
YWHAH	FOXO4	0.954		mutually_exclusive (P31947)
YWHAZ	PTOV1	0.953	0.472703862661
YWHAQ	DENND4A	0.952	0.338	structurally_consistent (dimer)
YWHAQ	KIAA0930	0.952	0.292436781609	structurally_consistent (dimer)
YWHAZ	HOMEZ	0.952	0.39464516129	mutually_exclusive (P27348)
YWHAG	CLASP1	0.951	0.346055555556
PLEKHG5	YWHAH	0.951
PLEKHG5	YWHAG	0.95
SRGAP1	YWHAQ	0.95	0.498
FOXO4	YWHAB	0.949
GPSM3	SFN	0.949	0.158
YWHAG	CDR2L	0.948	0.55
PI4KB	YWHAB	0.948	0.224714589666
YWHAZ	MARK3	0.948	0.288909090909
YWHAZ	FOXO1	0.948	0.638	mutually_exclusive (P27348)
SPATA13	YWHAE	0.946	0.392366471735
CDC25B	YWHAE	0.944	0.503
PLEKHG5	YWHAE	0.943
YWHAZ	IRS2	0.941	0.477761904762
YWHAG	ANKRD55	0.937
YWHAG	FOXO4	0.937
SRGAP2	YWHAZ	0.936	0.576
YWHAZ	DENND4A	0.936	0.320166666667	mutually_exclusive (P27348)
ANKRD55	YWHAH	0.936
MAP3K2	YWHAB	0.936	0.232
DMTN	YWHAH	0.935	0.366116351733
BAD	YWHAE	0.932	0.198
GPSM3	YWHAE	0.932	0.284
CRTC1	YWHAQ	0.93	0.208	structurally_consistent (dimer)
GPSM3	YWHAG	0.925	0.474
SYDE2	YWHAQ	0.924
PACS2	YWHAZ	0.921	0.544106400665
PI4KB	YWHAQ	0.921	0.246
SYDE2	YWHAG	0.918
HOMEZ	YWHAH	0.917	0.328	mutually_exclusive (P27348)
MAP3K3	YWHAB	0.916	0.336264388826	mutually_exclusive (Q13163)
GPSM3	YWHAH	0.911	0.316	mutually_exclusive (P27348)
YWHAQ	FOXO3	0.911	0.446
PLEKHG5	YWHAQ	0.909
YWHAQ	HDAC5	0.903	0.4575
YWHAQ	SASH1	0.903	0.326	structurally_consistent (dimer)
PLEKHG5	YWHAB	0.902
SASH1	YWHAB	0.901	0.328
PLEKHG5	SFN	0.901
SRGAP2	YWHAQ	0.9	0.478	structurally_consistent (dimer)
FOXO3	YWHAB	0.899	0.382
SPIRE2	BRAF	0.898
YWHAZ	MARK1	0.888	0.318266666667
BRAF	MARK3	0.88	0.138
YWHAZ	CRTC1	0.876	0.251575264844	mutually_exclusive (P27348)
HOMEZ	YWHAQ	0.87	0.484	structurally_consistent (dimer)
KIAA0930	YWHAE	0.865	0.344027324121
YWHAQ	SPIRE2	0.854
SAMD4B	YWHAQ	0.853	0.346
SFN	SPATA13	0.843	0.214875
SPIRE2	IRS2	0.838
SFN	SAMD4A	0.835	0.356
YWHAZ	HDAC5	0.831	0.513774193548
YWHAG	ARHGEF38	0.829
YWHAZ	PTPN3	0.802	0.506
YWHAZ	SYDE2	0.782
SPIRE2	SPIRE1	0.781
YWHAZ	PLEKHA7	0.777	0.351173076923
PTOV1	YWHAE	0.767	0.354133333333
YWHAZ	CLASP1	0.754	0.274
SAMD4A	MARK3	0.723	0.09
PLEKHA7	YWHAQ	0.723	0.417142857143
YWHAZ	FOXO3	0.697	0.573297297297
IRS2	MARK3	0.695	0.116
MARK1	MARK3	0.683	0.152
SRGAP1	YWHAZ	0.672	0.308655751956
MAP3K3	FOXO1	0.665	0.11
SPIRE2	MARK3	0.661
MAP3K3	FOXO3	0.646	0.108
TFEB	IRS2	0.617	0.168
PACS2	YWHAE	0.611	0.501679479865
ARHGEF38	YWHAB	0.607
TFEB	BAD	0.605	0.08
PFKFB2	SPIRE1	0.605	0.042
PLEKHA7	SPIRE1	0.605	0.092
MARK1	TFEB	0.605	0.112
CDC25B	FOXO3	0.605	0.138
CDC25B	FAM53B	0.605
PLEKHA7	PFKFB2	0.605	0.044
CDC25B	TFEB	0.605	0.112
MAP3K3	BAD	0.582	0.058
MAP3K3	CDC25B	0.582	0.078
SFN	CDC25B	0.577	0.242
TFEB	FOXO1	0.576	0.15
YWHAZ	ARHGEF38	0.571
FOXO3	TFEB	0.566	0.046
DENND4A	IRS2	0.566	0.08
IRS2	FOXO1	0.564	0.09
FOXO3	BAD	0.561	0.132
FAM53B	BAD	0.561
PI4KB	FOXO3	0.556	0.07
SAMD4B	FOXO1	0.549	0.108
SAMD4B	IRS2	0.548	0.1
CRTC1	FOXO3	0.543	0.208
HDAC4	MAP3K2	0.54	0.082
CDC25B	SPIRE1	0.54	0.132
HDAC4	TIAM1	0.54	0.218
HDAC4	FOXO3	0.54	0.168
HDAC4	HDAC5	0.54	0.158
HDAC4	TFEB	0.54	0.094
HDAC4	CRTC1	0.54	0.188
HDAC4	FAM53B	0.54
CLASP1	FAM53B	0.539
TFEB	BRAF	0.539	0.118
PLEKHA7	BAD	0.539	0.088
CRTC1	CLASP1	0.539	0.124
CLASP1	BAD	0.539	0.088
PI4KB	PFKFB2	0.539	0.058
SASH1	TFEB	0.539	0.092
PFKFB2	BAD	0.539	0.068	mutually_exclusive (P27348)
PI4KB	TFEB	0.539	0.078
HDAC4	SASH1	0.539	0.09
CDC25B	SASH1	0.539	0.07	mutually_exclusive (P27348)
CDC25B	BAD	0.539	0.126	mutually_exclusive (P27348)
SRGAP2	CDC25B	0.539	0.0884395604396	mutually_exclusive (P27348)
PFKFB2	CLASP1	0.539	0.082
PI4KB	IRS2	0.539	0.076
CLASP1	TFEB	0.539	0.082
PFKFB2	KIAA0930	0.539	0.092	mutually_exclusive (P27348)
PI4KB	SPIRE1	0.539	0.086
SASH1	FOXO1	0.539	0.202	mutually_exclusive (P27348)
CRTC1	SASH1	0.539	0.1	mutually_exclusive (P27348)
FOXO3	KIAA0930	0.539	0.08
SRGAP2	BAD	0.539	0.1	mutually_exclusive (P27348)
KIAA0930	SPIRE1	0.539	0.05
PI4KB	TIAM1	0.539	0.118
PI4KB	CRTC1	0.539	0.112
PLEKHA7	SASH1	0.539	0.11
SASH1	HDAC5	0.539	0.132
SASH1	BAD	0.539	0.048	mutually_exclusive (P27348)
SASH1	FOXO3	0.539	0.126
CLASP1	CDC25B	0.539	0.07
PFKFB2	SASH1	0.539	0.066	mutually_exclusive (P27348)
SASH1	IRS2	0.539	0.1
PI4KB	CDC25B	0.539	0.118
PLEKHA7	DENND4A	0.539	0.084
CLASP1	KIAA0930	0.539	0.108
PLEKHA7	PI4KB	0.539	0.044
SASH1	TIAM1	0.539	0.22
CDC25B	DENND4A	0.539	0.108
CLASP1	SPIRE1	0.539	0.102
PLEKHA7	CDC25B	0.539	0.126
PFKFB2	DENND4A	0.539	0.028	mutually_exclusive (P27348)
MAP3K2	SASH1	0.539	0.074	mutually_exclusive (P27348)
PI4KB	BAD	0.539	0.064
PLEKHA7	KIAA0930	0.539	0.058
CDC25B	KIAA0930	0.539	0.128	mutually_exclusive (P27348)
PI4KB	FAM53B	0.539
PI4KB	MAP3K2	0.539	0.166
SPIRE1	BAD	0.539	0.124
TFEB	KIAA0930	0.539	0.09
HDAC4	CLASP1	0.539	0.13
PFKFB2	CDC25B	0.539	0.054	mutually_exclusive (P27348)
CLASP1	MAP3K2	0.539	0.106
CLASP1	IRS2	0.539	0.156
CLASP1	TIAM1	0.539	0.092
SASH1	FAM53B	0.539
SPIRE2	SASH1	0.539
KIAA0930	BAD	0.539	0.064
SRGAP2	SPIRE1	0.539	0.084
KIAA0930	FAM53B	0.539
PLEKHA7	CLASP1	0.539	0.072
SASH1	SPIRE1	0.539	0.142
SAMD4B	SASH1	0.539	0.058
SASH1	SAMD4A	0.539	0.086
SRGAP2	PFKFB2	0.539	0.038	mutually_exclusive (P27348)
MARK1	FAM53B	0.539
MARK1	FOXO3	0.539	0.144
CRTC1	IRS2	0.538	0.144
MAP3K2	TFEB	0.534	0.09
IRS2	BAD	0.534	0.098
PLEKHA7	MAP3K2	0.534	0.048
TFEB	SPIRE1	0.534	0.106
PFKFB2	TFEB	0.534	0.108
CRTC1	SPIRE1	0.534	0.108
MARK1	IRS2	0.534	0.12
PFKFB2	FAM53B	0.534
CDC25B	HDAC5	0.534	0.088
CRTC1	MAP3K2	0.534	0.09	mutually_exclusive (P27348)
HDAC4	CDC25B	0.534	0.104
CRTC1	CDC25B	0.534	0.122	mutually_exclusive (P27348)
IRS2	FAM53B	0.534
MAP3K2	IRS2	0.534	0.078
SRGAP2	MAP3K2	0.534	0.084	mutually_exclusive (P27348)
PFKFB2	IRS2	0.534	0.076
HDAC4	BAD	0.534	0.08
HDAC4	KIAA0930	0.534	0.078
CRTC1	TIAM1	0.534	0.156
CDC25B	IRS2	0.534	0.118
TFEB	TIAM1	0.534	0.076
CDC25B	TIAM1	0.534	0.162
TIAM1	IRS2	0.534	0.168
HDAC4	DENND4A	0.534	0.082
TIAM1	KIAA0930	0.534	0.04
MAP3K2	DENND4A	0.534	0.064
MAP3K2	CDC25B	0.534	0.154	mutually_exclusive (P27348)
CRTC1	KIAA0930	0.534	0.066	mutually_exclusive (P27348)
MAP3K2	TIAM1	0.534	0.096
HDAC4	PI4KB	0.534	0.108
MAP3K2	FAM53B	0.534
CRTC1	PFKFB2	0.534	0.04	mutually_exclusive (P27348)
PFKFB2	FOXO3	0.534	0.076
TIAM1	DENND4A	0.534	0.155
MAP3K2	KIAA0930	0.534	0.156	mutually_exclusive (P27348)
IRS2	KIAA0930	0.534	0.134
PFKFB2	MAP3K2	0.534	0.076	mutually_exclusive (P27348)
PLEKHA7	FOXO3	0.534	0.106
HDAC4	PLEKHA7	0.534	0.13
SRGAP2	TIAM1	0.534	0.246
PLEKHA7	HDAC5	0.534	0.086
TIAM1	BAD	0.534	0.126
SRGAP2	HDAC4	0.534	0.128
TIAM1	HDAC5	0.534	0.102
TIAM1	FAM53B	0.534
MAP3K2	BAD	0.534	0.056	mutually_exclusive (P27348)
IRS2	SPIRE1	0.534	0.08
MAP3K2	FOXO3	0.534	0.146
TIAM1	SPIRE1	0.534	0.202
TFEB	FAM53B	0.534
PLEKHA7	TFEB	0.534	0.092
SPIRE1	FAM53B	0.534
PLEKHA7	FAM53B	0.534
HDAC4	SPIRE1	0.534	0.204
MAP3K2	SPIRE1	0.534	0.08
FOXO3	TIAM1	0.534	0.218
CRTC1	BAD	0.534	0.214	mutually_exclusive (P27348)
PLEKHA7	CRTC1	0.534	0.088
PFKFB2	TIAM1	0.534	0.124
HDAC4	PFKFB2	0.534	0.046	mutually_exclusive (P27348)
SRGAP2	FOXO1	0.528	0.218133333333	mutually_exclusive (P27348)
ARHGEF38	YWHAQ	0.527
MAP3K3	HDAC4	0.517	0.144
SRGAP2	FAM53B	0.516
MAP3K3	SASH1	0.516	0.072
MAP3K3	PI4KB	0.516	0.134
MAP3K3	CLASP1	0.516	0.152
DENND4A	FAM53B	0.516
MAP3K3	KIAA0930	0.516	0.072
SRGAP2	IRS2	0.513	0.216
MAP3K3	SPIRE1	0.511	0.078
MAP3K3	PFKFB2	0.511	0.102
MAP3K3	PLEKHA7	0.511	0.094
MAP3K3	TIAM1	0.511	0.148
MAP3K3	TFEB	0.511	0.112
CRTC1	FAM53B	0.511
MAP3K3	IRS2	0.511	0.068
IRS2	PTPN3	0.504	0.126
CRTC1	TFEB	0.5	0.116
MAP3K3	YWHAE	0.497	0.609023076923
MARK1	SAMD4A	0.496	0.088
HDAC4	FOXO1	0.496	0.168
MAP3K2	FOXO1	0.496	0.168	mutually_exclusive (P27348)
TIAM1	FOXO1	0.496	0.16
CLASP1	FOXO3	0.495	0.164
TFEB	DENND4A	0.495	0.126
CLASP1	HDAC5	0.494	0.146
PLEKHA7	MARK1	0.494	0.082
MARK1	PFKFB2	0.494	0.09	mutually_exclusive (P27348)
MARK1	BAD	0.494	0.092	mutually_exclusive (P27348)
PLEKHA7	BRAF	0.494	0.14
HDAC4	MARK3	0.494	0.144
MARK1	KIAA0930	0.494	0.054
MARK1	CDC25B	0.494	0.08
MAP3K2	BRAF	0.494	0.156	mutually_exclusive (P27348)
BRAF	SPIRE1	0.494	0.076
TIAM1	BRAF	0.494	0.126
BRAF	BAD	0.494	0.134	mutually_exclusive (P27348)
PFKFB2	BRAF	0.494	0.084	mutually_exclusive (P27348)
MARK1	SPIRE1	0.494	0.12
CLASP1	FOXO1	0.494	0.116
CDC25B	BRAF	0.494	0.106	mutually_exclusive (P27348)
MAP3K2	MARK3	0.494	0.078
YWHAZ	TIAM1	0.493	0.42677992278
FOXO3	IRS2	0.491	0.09
TFEB	HDAC5	0.491	0.114
PI4KB	FOXO1	0.489	0.106
HDAC4	MARK1	0.489	0.144
CDC25B	FOXO1	0.489	0.162	mutually_exclusive (P27348)
FOXO3	SPIRE1	0.489	0.178
BAD	HDAC5	0.489	0.104	mutually_exclusive (P31947)
MARK1	TIAM1	0.489	0.124
MARK1	MAP3K2	0.489	0.13
MAP3K2	HDAC5	0.489	0.164
BAD	FOXO1	0.489	0.09	mutually_exclusive (P27348)
HDAC4	BRAF	0.489	0.0952
SPIRE1	FOXO1	0.489	0.158
PLEKHA7	FOXO1	0.489	0.112
KIAA0930	FOXO1	0.489	0.102	mutually_exclusive (P27348)
SPIRE1	HDAC5	0.489	0.17
PFKFB2	FOXO1	0.489	0.102	mutually_exclusive (P27348)
PFKFB2	HDAC5	0.489	0.062
PI4KB	HDAC5	0.482	0.126
SAMD4B	TFEB	0.48	0.096
SPIRE2	MAP3K2	0.48
PI4KB	KIAA0930	0.48	0.15
PI4KB	SASH1	0.48	0.064
PI4KB	CLASP1	0.48	0.14
HDAC4	SAMD4B	0.48	0.082
SAMD4B	CDC25B	0.48	0.106
PI4KB	SPIRE2	0.48
CLASP1	DENND4A	0.48	0.048
SAMD4B	BAD	0.48	0.078
SPIRE2	TFEB	0.48
SPIRE2	KIAA0930	0.48
PI4KB	SAMD4B	0.48	0.156
TIAM1	SAMD4A	0.48	0.12
PLEKHA7	SAMD4A	0.48	0.082
CRTC1	SAMD4B	0.48	0.03
PI4KB	SAMD4A	0.48	0.098
SPIRE2	CDC25B	0.48
SAMD4B	PFKFB2	0.48	0.04
SPIRE2	BAD	0.48
CRTC1	SAMD4A	0.48	0.082
SAMD4A	FOXO1	0.48	0.154
SRGAP2	KIAA0930	0.48	0.074	mutually_exclusive (P27348)
SPIRE2	TIAM1	0.48
CLASP1	SAMD4A	0.48	0.154
CLASP1	SPIRE2	0.48
CLASP1	SASH1	0.48	0.048
SAMD4B	TIAM1	0.48	0.132
DENND4A	BAD	0.48	0.058
DENND4A	KIAA0930	0.48	0.142
SAMD4B	FAM53B	0.48
SASH1	MARK3	0.48	0.111166666667
MARK1	SASH1	0.48	0.09
DENND4A	SPIRE1	0.48	0.132
TFEB	SAMD4A	0.48	0.102
PI4KB	DENND4A	0.48	0.134
PLEKHA7	SPIRE2	0.48
SPIRE2	SAMD4A	0.48
SAMD4A	BAD	0.48	0.112
SAMD4A	SPIRE1	0.48	0.148
SAMD4B	SPIRE1	0.48	0.07
SAMD4A	FAM53B	0.48
SASH1	DENND4A	0.48	0.076
PFKFB2	SAMD4A	0.48	0.07
SAMD4A	HDAC5	0.48	0.138
SRGAP2	PI4KB	0.48	0.15
SAMD4A	BRAF	0.48	0.08
HDAC4	SAMD4A	0.48	0.124
SAMD4B	KIAA0930	0.48	0.052
SAMD4A	KIAA0930	0.48	0.048
MAP3K2	SAMD4A	0.48	0.098
CDC25B	SAMD4A	0.48	0.08
SRGAP2	SASH1	0.48	0.104	mutually_exclusive (P27348)
HDAC4	SPIRE2	0.48
FOXO3	SAMD4A	0.48	0.128
SASH1	BRAF	0.48	0.062	mutually_exclusive (P27348)
SAMD4B	SPIRE2	0.48
SASH1	KIAA0930	0.48	0.066	mutually_exclusive (P27348)
SAMD4B	MAP3K2	0.48	0.09
PFKFB2	SPIRE2	0.48
GPSM3	MARK1	0.479		mutually_exclusive (P27348)
KIAA0930	HDAC5	0.477	0.132	mutually_exclusive (P31947)
SAMD4A	IRS2	0.476	0.196
FAM53B	FOXO1	0.472
FOXO3	BRAF	0.471	0.126
BRAF	HDAC5	0.471	0.206
BRAF	FAM53B	0.471
CRTC1	BRAF	0.471	0.072	mutually_exclusive (P27348)
SRGAP1	YWHAE	0.47	0.335433138402
SRGAP2	FOXO3	0.469	0.208
CRTC1	DENND4A	0.467	0.056	mutually_exclusive (P27348)
FOXO3	FAM53B	0.466
DENND4A	BRAF	0.466	0.13	mutually_exclusive (P27348)
MARK1	FOXO1	0.466	0.138	mutually_exclusive (P27348)
BRAF	FOXO1	0.466	0.158	mutually_exclusive (P27348)
SRGAP2	BRAF	0.466	0.144	mutually_exclusive (P27348)
CRTC1	MARK1	0.466	0.098	mutually_exclusive (P27348)
FAM53B	HDAC5	0.466
MARK1	HDAC5	0.466	0.142
FOXO3	HDAC5	0.463	0.348
DENND4A	SAMD4A	0.461	0.144
HDAC5	FOXO1	0.46	0.15
CRTC1	FOXO1	0.459	0.092	mutually_exclusive (P27348)
SPIRE2	FOXO3	0.457
SPIRE2	FAM53B	0.457
CRTC1	SPIRE2	0.457
SPIRE2	FOXO1	0.457
MAP3K3	SAMD4B	0.457	0.094
MAP3K3	SAMD4A	0.457	0.154
SRGAP2	SPIRE2	0.457
SPIRE2	DENND4A	0.457
MARK1	SPIRE2	0.457
SPIRE2	HDAC5	0.457
PLEKHA7	PTPN3	0.456	0.138
CRTC1	HDAC5	0.454	0.112
DENND4A	FOXO1	0.454	0.076	mutually_exclusive (P27348)
YWHAZ	FOXO4	0.449		mutually_exclusive (P31947)
PTPN3	YWHAE	0.448	0.454925925926
SYDE2	PTOV1	0.447
TFEB	PTOV1	0.447	0.09
MAP3K3	PTOV1	0.447	0.074
SMTNL2	DENND4A	0.447
HOMEZ	PTOV1	0.447	0.096
PFKFB2	SFN	0.447	0.432461538462	mutually_exclusive (P27348)
SFN	SASH1	0.447	0.312
PLEKHA7	PTOV1	0.447	0.142
SFN	FOXO3	0.447	0.452
SRGAP1	SFN	0.447	0.244685714286
MARK1	PTOV1	0.447	0.128
TIAM1	PTOV1	0.447	0.114
SFN	IRS2	0.447	0.336
SRGAP2	SMTNL2	0.447		mutually_exclusive (P27348)
PTOV1	KIAA0930	0.447	0.094	mutually_exclusive (P31947)
PACS2	PTOV1	0.447	0.104
SYDE2	SFN	0.447
CRTC1	PTOV1	0.447	0.094
SFN	FOXO1	0.447	0.546	mutually_exclusive (P27348)
PI4KB	SMTNL2	0.447
MAP3K2	PTOV1	0.447	0.064
SRGAP2	PTOV1	0.447	0.176
HDAC4	SFN	0.447	0.394461139896
SFN	HDAC5	0.447	0.274417508418	structurally_consistent (dimer)
SFN	TIAM1	0.447	0.368548387097
PTOV1	HDAC5	0.447	0.14	mutually_exclusive (P31947)
PTOV1	FAM53B	0.447
PFKFB2	PTOV1	0.447	0.106
PTOV1	BRAF	0.447	0.062
PACS2	SFN	0.447	0.314
PTOV1	BAD	0.447	0.094	mutually_exclusive (P31947)
SMTNL2	MARK3	0.447		mutually_exclusive (P31947)
SYDE2	YWHAE	0.447
PTOV1	SPIRE1	0.447	0.138
CDC25B	PTOV1	0.447	0.088
PTOV1	PTPN3	0.447	0.108
SASH1	PTOV1	0.447	0.08
SFN	PTPN3	0.447	0.32
FOXO3	PTOV1	0.447	0.116
CRTC1	SFN	0.447	0.171767901235	mutually_exclusive (P27348)
SRGAP2	CLASP1	0.438	0.146405594406
SPIRE1	MARK3	0.436	0.136
PFKFB2	MARK3	0.436	0.048
KIAA0930	MARK3	0.436	0.082
BAD	MARK3	0.436	0.1	mutually_exclusive (P31947)
MARK1	CLASP1	0.436	0.098
TIAM1	MARK3	0.436	0.13
PI4KB	BRAF	0.436	0.104
BRAF	KIAA0930	0.436	0.11	mutually_exclusive (P27348)
CDC25B	MARK3	0.436	0.082
PI4KB	MARK1	0.436	0.148
CLASP1	SMTNL2	0.426
SMTNL2	BRAF	0.426		mutually_exclusive (P27348)
DENND4A	MARK3	0.424	0.044
SAMD4B	MARK1	0.416	0.078
FAM53B	MARK3	0.413
MARK1	BRAF	0.413	0.122
SRGAP2	MARK1	0.413	0.16
MARK1	DENND4A	0.4	0.072	mutually_exclusive (P27348)
ARHGEF38	YWHAH	0.397
SRGAP2	SAMD4B	0.396	0.034
SASH1	YWHAE	0.393	0.344
YWHAZ	SASH1	0.393	0.507145833333
PLEKHA7	IRS2	0.39	0.158
SRGAP2	MARK3	0.389	0.072
PACS2	SPIRE1	0.385	0.092
SYDE2	BAD	0.385
MARK1	PTPN3	0.385	0.122
PACS2	PFKFB2	0.385	0.064
PACS2	HOMEZ	0.385	0.076
PLEKHA7	HOMEZ	0.385	0.066
HOMEZ	SPIRE1	0.385	0.074
SRGAP1	MARK1	0.385	0.136
SRGAP1	CDC25B	0.385	0.156
SYDE2	CDC25B	0.385
HOMEZ	PFKFB2	0.385	0.136	mutually_exclusive (P27348)
SYDE2	MARK1	0.385
CDC25B	PTPN3	0.385	0.092
PACS2	PLEKHA7	0.385	0.1
SRGAP1	BAD	0.385	0.08
PTPN3	BAD	0.385	0.128
PFKFB2	YWHAE	0.37	0.49695890411	mutually_exclusive (P27348)
SPIRE1	YWHAE	0.37	0.368
SAMD4B	HDAC5	0.359	0.21
IRS2	HDAC5	0.353	0.102
SFN	MARK3	0.351	0.112	structurally_consistent (dimer)
SYDE2	FOXO3	0.35
MARK1	YWHAE	0.334	0.469033138402
SYDE2	FOXO1	0.324
HDAC4	SYDE2	0.324
SYDE2	FOXO4	0.324
FOXO3	FOXO4	0.324
PTPN3	FOXO1	0.324	0.162
HDAC4	PTPN3	0.324	0.134
SRGAP1	FOXO1	0.324	0.212
SRGAP1	HDAC4	0.324	0.204
PACS2	PTPN3	0.319	0.088
SYDE2	SPIRE1	0.319
SYDE2	FAM53B	0.319
SYDE2	HDAC5	0.319
TFEB	PTPN3	0.319	0.086
MAP3K3	PTPN3	0.319	0.138
SYDE2	PFKFB2	0.319
CRTC1	HOMEZ	0.319	0.158	mutually_exclusive (P27348)
PACS2	FAM53B	0.319
HOMEZ	TIAM1	0.319	0.136
SRGAP1	TIAM1	0.319	0.256
HOMEZ	TFEB	0.319	0.044
PTPN3	SPIRE1	0.319	0.13
MAP3K2	PTPN3	0.319	0.144
SYDE2	PTPN3	0.319
PTPN3	HDAC5	0.319	0.154
PACS2	SYDE2	0.319
FOXO3	PTPN3	0.319	0.2
CRTC1	PTPN3	0.319	0.18
PACS2	SRGAP1	0.319	0.212
PACS2	TIAM1	0.319	0.16
PACS2	CRTC1	0.319	0.13
HOMEZ	FOXO1	0.319	0.114	mutually_exclusive (P27348)
PACS2	FOXO3	0.319	0.146
SRGAP1	PFKFB2	0.319	0.076
HOMEZ	FAM53B	0.319
MAP3K3	PACS2	0.319	0.096
PFKFB2	PTPN3	0.319	0.084
HDAC4	HOMEZ	0.319	0.204	mutually_exclusive (P27348)
SYDE2	PLEKHA7	0.319
TIAM1	PTPN3	0.319	0.144
SRGAP1	SPIRE1	0.319	0.156
PACS2	TFEB	0.319	0.112
SYDE2	TIAM1	0.319
SRGAP1	PTPN3	0.319	0.186
MAP3K3	SYDE2	0.319
HOMEZ	FOXO3	0.319	0.126
PTPN3	FAM53B	0.319
PACS2	MAP3K2	0.319	0.072
MAP3K3	SRGAP1	0.319	0.134
MAP3K3	HOMEZ	0.319	0.07
SYDE2	MAP3K2	0.319
SRGAP1	HOMEZ	0.319	0.072
SYDE2	CRTC1	0.319
SRGAP1	FAM53B	0.319
SRGAP1	IRS2	0.319	0.272
SRGAP1	TFEB	0.319	0.142
SRGAP1	SYDE2	0.319
SRGAP1	HDAC5	0.319	0.082
SYDE2	IRS2	0.319
SRGAP1	CRTC1	0.319	0.144
PACS2	HDAC4	0.319	0.15
SRGAP1	MAP3K2	0.319	0.072
HOMEZ	MAP3K2	0.319	0.178	mutually_exclusive (P27348)
SRGAP1	FOXO3	0.319	0.148
SYDE2	HOMEZ	0.319
HOMEZ	IRS2	0.319	0.116
HOMEZ	PTPN3	0.319	0.094
PACS2	FOXO1	0.319	0.198
PACS2	HDAC5	0.319	0.096
SRGAP1	PLEKHA7	0.319	0.154
SYDE2	TFEB	0.319
FOXO3	FOXO1	0.317	0.168
SRGAP2	TFEB	0.301	0.154
SRGAP2	PLEKHA7	0.301	0.112
GPSM3	MARK3	0.3	0.044
SRGAP2	HDAC5	0.298	0.208
MAP3K3	MARK1	0.294	0.094
PACS2	BAD	0.29	0.144
SRGAP2	SYDE2	0.29
SYDE2	KIAA0930	0.29
HOMEZ	BAD	0.29	0.058	mutually_exclusive (P27348)
SYDE2	DENND4A	0.29
PTPN3	KIAA0930	0.29	0.148
PACS2	MARK1	0.29	0.128
SRGAP1	KIAA0930	0.29	0.088
PACS2	CDC25B	0.29	0.082
HOMEZ	CDC25B	0.29	0.08	mutually_exclusive (P27348)
DENND4A	PTPN3	0.29	0.102
HOMEZ	MARK1	0.29	0.148	mutually_exclusive (P27348)
SRGAP1	DENND4A	0.29	0.086
SRGAP2	DENND4A	0.283	0.034
SYDE2	BRAF	0.283
SYDE2	PI4KB	0.283
PACS2	CLASP1	0.283	0.064
PI4KB	HOMEZ	0.283	0.186
HOMEZ	SASH1	0.283	0.07	mutually_exclusive (P27348)
PACS2	KIAA0930	0.283	0.066
PACS2	BRAF	0.283	0.142
PACS2	DENND4A	0.283	0.116
SYDE2	CLASP1	0.283
CLASP1	PTPN3	0.283	0.19
SYDE2	SASH1	0.283
PI4KB	PTPN3	0.283	0.14
FOXO4	IRS2	0.283
SRGAP1	CLASP1	0.283	0.166
SASH1	FOXO4	0.283
SAMD4B	FOXO4	0.283
HOMEZ	KIAA0930	0.283	0.052	mutually_exclusive (P27348)
PACS2	SASH1	0.283	0.116
SRGAP1	PI4KB	0.283	0.178
SRGAP1	BRAF	0.283	0.15
HOMEZ	CLASP1	0.283	0.126
BRAF	PTPN3	0.283	0.104
FOXO4	HDAC5	0.283		mutually_exclusive (P31947)
CRTC1	FOXO4	0.283
PACS2	PI4KB	0.283	0.134
MAP3K2	FOXO4	0.283
SRGAP1	SASH1	0.283	0.136
HDAC4	FOXO4	0.283
FOXO4	FOXO1	0.283
HOMEZ	DENND4A	0.283	0.07	mutually_exclusive (P27348)
HOMEZ	BRAF	0.283	0.218	mutually_exclusive (P27348)
SASH1	PTPN3	0.283	0.09
FOXO3	DENND4A	0.282	0.1
CRTC1	YWHAE	0.28	0.355333333333
SRGAP2	CRTC1	0.278	0.13	mutually_exclusive (P27348)
DENND4A	HDAC5	0.278	0.086
SRGAP2	YWHAE	0.278	0.42
CLASP1	FOXO4	0.277
HOMEZ	YWHAE	0.277	0.459033138402	mutually_exclusive (P27348)
MAP3K3	DENND4A	0.275	0.156
MAP3K3	SRGAP2	0.275	0.172133333333
MAP3K3	CRTC1	0.271	0.084
FOXO1	MARK3	0.27	0.088
HDAC5	MARK3	0.27	0.146	mutually_exclusive (P31947)
CRTC1	MARK3	0.27	0.092
PACS2	SAMD4B	0.262	0.068
YWHAZ	SPIRE2	0.261
SAMD4B	FOXO3	0.254	0.132
TFEB	MARK3	0.254	0.112
SRGAP2	SAMD4A	0.254	0.14
SAMD4B	DENND4A	0.254	0.04
HDAC5	YWHAE	0.249	0.52880733195	mutually_exclusive (P31947)
SAMD4B	MARK3	0.249	0.062
SMTNL2	TIAM1	0.246
MARK1	SMTNL2	0.246		mutually_exclusive (P27348)
SYDE2	SMTNL2	0.246
SMTNL2	KIAA0930	0.246
SPIRE2	SMTNL2	0.246
HOMEZ	SMTNL2	0.246		mutually_exclusive (P27348)
SMTNL2	CDC25B	0.246		mutually_exclusive (P27348)
SMTNL2	FOXO3	0.246
SMTNL2	PTPN3	0.246
MAP3K3	SMTNL2	0.246
SMTNL2	TFEB	0.246
MARK1	SFN	0.246	0.36
SMTNL2	SAMD4A	0.246
SMTNL2	FAM53B	0.246
PTOV1	FOXO1	0.246	0.142
PLEKHA7	SMTNL2	0.246
SMTNL2	SPIRE1	0.246
PACS2	SMTNL2	0.246
PFKFB2	SMTNL2	0.246		mutually_exclusive (P27348)
SRGAP1	SMTNL2	0.246
SAMD4B	BRAF	0.245	0.092
PI4KB	MARK3	0.243	0.136
MAP3K3	BRAF	0.241	0.08
FOXO4	PTOV1	0.239		mutually_exclusive (P31947)
SFN	SPIRE1	0.239	0.224564102564
PLEKHA7	SFN	0.239	0.3584
HOMEZ	SAMD4A	0.238	0.122
SAMD4B	SMTNL2	0.238
SMTNL2	IRS2	0.238
PTPN3	MARK3	0.238	0.222
SYDE2	MARK3	0.238
SMTNL2	SASH1	0.238		mutually_exclusive (P27348)
SRGAP1	MARK3	0.238	0.14
MAP3K3	FOXO4	0.238
PI4KB	FOXO4	0.238
CDC25B	FOXO4	0.238
FOXO4	PTPN3	0.238
SYDE2	SPIRE2	0.238
HOMEZ	SPIRE2	0.238
FOXO4	FAM53B	0.238
FOXO4	KIAA0930	0.238		mutually_exclusive (P31947)
PACS2	SPIRE2	0.238
SMTNL2	FOXO4	0.238		mutually_exclusive (P31947)
SPIRE2	FOXO4	0.238
SMTNL2	HDAC5	0.238		mutually_exclusive (P31947)
FOXO4	DENND4A	0.238
SMTNL2	FOXO1	0.238		mutually_exclusive (P27348)
SRGAP1	PTOV1	0.238	0.118
MAP3K2	SMTNL2	0.238		mutually_exclusive (P27348)
HDAC4	SMTNL2	0.238
PLEKHA7	FOXO4	0.238
MARK1	FOXO4	0.238
FOXO4	BRAF	0.238
PACS2	MARK3	0.238	0.102
CRTC1	SMTNL2	0.238		mutually_exclusive (P27348)
SPIRE2	PTPN3	0.238
SRGAP1	SPIRE2	0.238
FOXO4	SAMD4A	0.238
SYDE2	SAMD4A	0.238
SAMD4A	PTPN3	0.238	0.124
SMTNL2	BAD	0.238
SYDE2	SAMD4B	0.238
FOXO4	TFEB	0.238
FOXO4	TIAM1	0.238
FOXO4	SPIRE1	0.238
PACS2	FOXO4	0.238
SRGAP1	FOXO4	0.238
FOXO4	BAD	0.238		mutually_exclusive (P31947)
PACS2	SAMD4A	0.238	0.076
HOMEZ	FOXO4	0.238
SRGAP1	SAMD4A	0.238	0.246
PFKFB2	FOXO4	0.238
MAP3K3	HDAC5	0.237	0.108
MAP3K3	FAM53B	0.237
HOMEZ	SFN	0.234	0.35725	mutually_exclusive (P27348)
SAMD4B	PTPN3	0.232	0.114
MAP3K3	SPIRE2	0.231
PLEKHA7	TIAM1	0.23	0.14
FOXO4	MARK3	0.224		mutually_exclusive (P31947)
HOMEZ	MARK3	0.224	0.134
SRGAP2	FOXO4	0.224
PLEKHA7	MARK3	0.221	0.05
CLASP1	BRAF	0.219	0.174
PTOV1	MARK3	0.218	0.098	mutually_exclusive (P31947)
PACS2	IRS2	0.213	0.098
HOMEZ	HDAC5	0.213	0.236
SAMD4B	SFN	0.208	0.09
FOXO3	MARK3	0.201	0.222
MAP3K3	MARK3	0.201	0.09
SRGAP2	PTPN3	0.191	0.132
SAMD4B	PTOV1	0.189	0.052
SRGAP2	SFN	0.189	0.266
SFN	FOXO4	0.189		structurally_consistent (dimer)
SFN	DENND4A	0.189	0.203047619048	mutually_exclusive (P27348)
FOXO1	YWHAE	0.18	0.476746666667	mutually_exclusive (P27348)
CDR2L	FOXO1	0.179	0.146
DENND4A	PTOV1	0.177	0.034
SAMD4B	CDR2L	0.176	0.09
CDR2L	TFEB	0.172	0.126
PLEKHA7	CDR2L	0.171	0.108
SRGAP2	HOMEZ	0.168	0.18	mutually_exclusive (P27348)
PACS2	SRGAP2	0.168	0.156133333333
CDR2L	SPIRE2	0.166
CLASP1	MARK3	0.165	0.084
FOXO4	YWHAE	0.156		mutually_exclusive (P31947)
PI4KB	SFN	0.155	0.116
PI4KB	PTOV1	0.155	0.128
CDR2L	SAMD4A	0.155	0.146
CDR2L	SASH1	0.155	0.114
SRGAP1	SAMD4B	0.153	0.136
SAMD4B	HOMEZ	0.153	0.084
CLASP1	SFN	0.151	0.173909090909
CDR2L	SPIRE1	0.147	0.152
PFKFB2	CDR2L	0.147	0.166
CDR2L	BAD	0.147	0.13
CLASP1	CDR2L	0.147	0.108
CDR2L	IRS2	0.146	0.134
TIAM1	YWHAE	0.146	0.445033138402
PI4KB	CDR2L	0.145	0.198
SPIRE2	YWHAE	0.145
CDR2L	KIAA0930	0.144	0.106
PLEKHA7	SAMD4B	0.144	0.072
MARK1	CDR2L	0.142	0.168
CDR2L	BRAF	0.14	0.116
CDR2L	DENND4A	0.138	0.064
CDR2L	MAP3K2	0.133	0.222
CDR2L	TIAM1	0.133	0.148
HDAC4	CDR2L	0.133	0.13
CDR2L	CDC25B	0.133	0.098
CDR2L	FAM53B	0.128
ANKRD55	SFN	0.128
CDR2L	HDAC5	0.125	0.206
HOMEZ	CDR2L	0.124	0.078
CDR2L	FOXO3	0.12	0.136
CRTC1	CDR2L	0.12	0.068
DENND4A	YWHAE	0.116	0.12	mutually_exclusive (P27348)
PLEKHG5	DMTN	0.113
SFN	SPIRE2	0.096
CLASP1	PTOV1	0.096	0.108
SPIRE2	PTOV1	0.096
SAMD4A	PTOV1	0.096	0.066
PLEKHG5	MARK3	0.095
CDR2L	SMTNL2	0.092
PI4KB	YWHAE	0.086	0.21
PLEKHG5	PTOV1	0.082
YWHAG	MAP2K5	0.082	0.216
DMTN	PTOV1	0.081	0.11
PACS2	CDR2L	0.08	0.092
PLEKHG5	MARK1	0.079
DMTN	KIAA0930	0.079	0.064	mutually_exclusive (P27348)
DMTN	FOXO3	0.079	0.118
PLEKHG5	PFKFB2	0.079
PLEKHG5	DENND4A	0.079
HOMEZ	DMTN	0.079	0.092	mutually_exclusive (P27348)
DMTN	TFEB	0.079	0.126
PLEKHG5	SAMD4B	0.079
DMTN	SASH1	0.079	0.152	mutually_exclusive (P27348)
PLEKHG5	HDAC5	0.079
PLEKHG5	FOXO4	0.079
CRTC1	DMTN	0.079	0.09	mutually_exclusive (P27348)
PI4KB	DMTN	0.079	0.104
PLEKHG5	PLEKHA7	0.079
MAP3K3	PLEKHG5	0.079
PFKFB2	DMTN	0.079	0.064	mutually_exclusive (P27348)
PLEKHG5	BAD	0.079
SRGAP1	PLEKHG5	0.079
PLEKHG5	SMTNL2	0.079
DMTN	MARK3	0.079	0.078
PLEKHG5	CRTC1	0.079
DMTN	FAM53B	0.079
SYDE2	DMTN	0.079
MAP3K3	DMTN	0.079	0.11
PACS2	DMTN	0.079	0.092
CLASP1	DMTN	0.079	0.054
PLEKHA7	DMTN	0.079	0.15
MARK1	DMTN	0.079	0.064	mutually_exclusive (P27348)
PACS2	PLEKHG5	0.079
PLEKHG5	PI4KB	0.079
PLEKHG5	CDC25B	0.079
PLEKHG5	SAMD4A	0.079
PLEKHG5	HDAC4	0.079
PLEKHG5	FOXO3	0.079
DMTN	CDC25B	0.079	0.138	mutually_exclusive (P27348)
HDAC4	DMTN	0.079	0.108
SRGAP2	PLEKHG5	0.079
DMTN	TIAM1	0.079	0.272
DMTN	PTPN3	0.079	0.182
PLEKHG5	SASH1	0.079
PLEKHG5	SPIRE2	0.079
PLEKHG5	CLASP1	0.079
DMTN	SAMD4A	0.079	0.074
PLEKHG5	PTPN3	0.079
PLEKHG5	HOMEZ	0.079
PLEKHG5	BRAF	0.079
PLEKHG5	KIAA0930	0.079
PLEKHG5	FAM53B	0.079
DMTN	HDAC5	0.079	0.076
DMTN	DENND4A	0.079	0.038
PLEKHG5	TFEB	0.079
SAMD4B	DMTN	0.079	0.058
DMTN	MAP3K2	0.079	0.08	mutually_exclusive (P27348)
DMTN	FOXO1	0.079	0.134	mutually_exclusive (P27348)
PLEKHG5	SPIRE1	0.079
DMTN	FOXO4	0.079
DMTN	BAD	0.079	0.08	mutually_exclusive (P27348)
PLEKHG5	TIAM1	0.079
DMTN	SMTNL2	0.079		mutually_exclusive (P27348)
DMTN	SPIRE1	0.079	0.108
PLEKHG5	FOXO1	0.079
SRGAP2	DMTN	0.079	0.13	mutually_exclusive (P27348)
PLEKHG5	MAP3K2	0.079
PLEKHG5	IRS2	0.079
DMTN	IRS2	0.079	0.134
DMTN	SPIRE2	0.079
SRGAP1	DMTN	0.079	0.166
PLEKHG5	SYDE2	0.079
DMTN	BRAF	0.079	0.096	mutually_exclusive (P27348)
CDR2L	DMTN	0.076	0.154
PLEKHA7	YWHAE	0.075	0.188
CDR2L	FOXO4	0.071
PLEKHG5	CDR2L	0.071
SYDE2	CDR2L	0.071
CDR2L	PTPN3	0.071	0.156
SRGAP1	CDR2L	0.071	0.19
ARHGEF38	SFN	0.071
SMTNL2	PTOV1	0.069		mutually_exclusive (P31947)
FOXO3	YWHAE	0.059	0.426900900901
SFN	PTOV1	0.057	0.256	structurally_consistent (dimer)
MAP3K3	CDR2L	0.057	0.124
SRGAP2	CDR2L	0.057	0.126
CLASP1	YWHAQ	0.055	0.286
MARK3	YWHAE	0.051	0.27
CLASP1	YWHAE	0.05	0.256
MAP2K5	DENND4A	0.043	0.08
SAMD4B	CLASP1	0.038	0.058
CDR2L	MARK3	0.037	0.134
GPSM3	PTOV1	0.035
CDR2L	PTOV1	0.027	0.16
MAP2K5	YWHAH	0.025	0.224
SFN	MAP2K5	0.017	0.15
MAP2K5	YWHAB	0.016	0.198626373626	structurally_consistent (dimer)
YWHAQ	MAP2K5	0.014	0.238
YWHAZ	MAP2K5	0.009	0.353111111111
CERT1	YWHAB	0.005	0.156726027397
CERT1	YWHAE	0.004	0.106
YWHAZ	CERT1	0.004	0.138769230769
CERT1	YWHAQ	0.004	0.172

Related Complexes

Genename	Complexes
PLEKHA7	huMAP3_01010.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CDR2L	huMAP3_01787.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SMTNL2	huMAP3_02971.1 huMAP3_04537.1 huMAP3_07596.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14527.1
PI4KB	huMAP3_01010.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_12954.1
TIAM1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
ARHGEF38	huMAP3_01699.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_10808.1 huMAP3_13503.1
MAP3K3	huMAP3_00011.1 huMAP3_03708.1 huMAP3_08523.1 huMAP3_10808.1 huMAP3_10861.1 huMAP3_12897.1
YWHAQ	huMAP3_01787.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
GPSM3	huMAP3_00362.1 huMAP3_01653.1 huMAP3_06782.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CERT1	huMAP3_01298.1 huMAP3_09812.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_11652.1 huMAP3_14496.1
DENND4A	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14817.1
PACS2	huMAP3_00173.1 huMAP3_04537.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10190.1 huMAP3_10808.1 huMAP3_12897.1
SAMD4A	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14098.1
SRGAP1	huMAP3_00235.1 huMAP3_04537.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10496.1 huMAP3_10808.1 huMAP3_11883.1 huMAP3_12561.1 huMAP3_12897.1 huMAP3_13128.1 huMAP3_13156.1 huMAP3_13524.1
TFEB	huMAP3_04102.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_08832.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13402.1 huMAP3_13503.1
ANKRD55	huMAP3_01787.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CDC25B	huMAP3_03088.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07002.1 huMAP3_07596.1 huMAP3_07691.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10829.1 huMAP3_12772.1 huMAP3_12897.1
IRS2	huMAP3_04537.1 huMAP3_07081.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_08092.1 huMAP3_09358.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_11629.1 huMAP3_12185.1 huMAP3_12897.1 huMAP3_14118.1
SPATA13	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
PLEKHG5	huMAP3_00362.1 huMAP3_01841.1 huMAP3_05451.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09174.1 huMAP3_09810.1 huMAP3_10180.1 huMAP3_10808.1 huMAP3_12897.1
SPIRE2	huMAP3_02462.1 huMAP3_04537.1 huMAP3_06108.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13929.1 huMAP3_15248.1
SASH1	huMAP3_03955.1 huMAP3_04051.1 huMAP3_04537.1 huMAP3_07306.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
MARK1	huMAP3_01298.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_09812.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_12897.1
SAMD4B	huMAP3_01010.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14098.1
FOXO3	huMAP3_03955.1 huMAP3_04051.1 huMAP3_04537.1 huMAP3_06135.1 huMAP3_07306.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
DMTN	huMAP3_01787.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_12991.1
HOMEZ	huMAP3_01010.1 huMAP3_04993.1 huMAP3_08920.1 huMAP3_10808.1 huMAP3_12897.1
SYDE2	huMAP3_00566.1 huMAP3_04537.1 huMAP3_06797.1 huMAP3_06971.1 huMAP3_08480.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10974.1 huMAP3_12897.1 huMAP3_14687.1
MARK3	huMAP3_06971.1 huMAP3_07596.1 huMAP3_09266.1 huMAP3_09812.1 huMAP3_10544.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_12897.1
LNP1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13672.1
PTOV1	huMAP3_04537.1 huMAP3_05308.1 huMAP3_07324.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_08154.1 huMAP3_09641.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1
MAP2K5	huMAP3_02733.1 huMAP3_03261.1 huMAP3_03708.1 huMAP3_10808.1 huMAP3_10861.1
BRAF	huMAP3_04537.1 huMAP3_04917.1 huMAP3_07588.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11448.1 huMAP3_12897.1
PTPN3	huMAP3_04537.1 huMAP3_06025.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11201.1 huMAP3_12897.1
KIAA0930	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11622.1 huMAP3_12897.1
YWHAB	huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
PFKFB2	huMAP3_01672.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CLASP1	huMAP3_01699.1 huMAP3_07247.1 huMAP3_08158.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_10808.1 huMAP3_12301.1
SFN	huMAP3_01787.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SPIRE1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13929.1 huMAP3_15248.1
FAM53B	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
BAD	huMAP3_04537.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11267.1 huMAP3_12897.1 huMAP3_13356.1
YWHAE	huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13503.1
YWHAH	huMAP3_04051.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07306.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
MAP3K2	huMAP3_02733.1 huMAP3_03708.1 huMAP3_08523.1 huMAP3_10808.1 huMAP3_10861.1 huMAP3_12897.1
YWHAZ	huMAP3_00362.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
HDAC5	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CRTC1	huMAP3_01010.1 huMAP3_04051.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13650.1
FOXO1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
HDAC4	huMAP3_00531.1 huMAP3_04537.1 huMAP3_06269.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09641.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_12897.1 huMAP3_14118.1
FOXO4	huMAP3_04051.1 huMAP3_04537.1 huMAP3_07424.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
YWHAG	huMAP3_01010.1 huMAP3_03955.1 huMAP3_06135.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SRGAP2	huMAP3_00235.1 huMAP3_02549.1 huMAP3_04537.1 huMAP3_05977.1 huMAP3_07838.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_09810.1 huMAP3_10496.1 huMAP3_10808.1 huMAP3_11531.1 huMAP3_12897.1
A0A1X9RU27	huMAP3_01787.1 huMAP3_03955.1 huMAP3_07424.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10808.1

Complex Portal: CPX-10978