hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10808.1

Complex Portal: CPX-10978

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
PLEKHA7	Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)	5	UniProt NCBI
CDR2L	Cerebellar degeneration-related protein 2-like (Paraneoplastic 62 kDa antigen)	5	UniProt NCBI
SMTNL2	Smoothelin-like protein 2	3	UniProt NCBI
PI4KB	Phosphatidylinositol 4-kinase beta (PI4K-beta) (PI4Kbeta) (PtdIns 4-kinase beta) (EC 2.7.1.67) (NPIK) (PI4K92) (PI4KIII)	5	UniProt NCBI
TIAM1	Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)	5	UniProt NCBI
ARHGEF38	Rho guanine nucleotide exchange factor 38	4	UniProt NCBI
MAP3K3	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3)	5	UniProt NCBI
YWHAQ	14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)	5	UniProt NCBI
GPSM3	G-protein-signaling modulator 3 (Activator of G-protein signaling 4) (G18.1b) (Protein G18)	5	UniProt NCBI
CERT1	Ceramide transfer protein (hCERT) (Collagen type IV alpha-3-binding protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11)	5	UniProt NCBI
DENND4A	C-myc promoter-binding protein (DENN domain-containing protein 4A)	5	UniProt NCBI
PACS2	Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein)	5	UniProt NCBI
SAMD4A	Protein Smaug homolog 1 (Smaug 1) (hSmaug1) (Sterile alpha motif domain-containing protein 4A) (SAM domain-containing protein 4A)	5	UniProt NCBI
SRGAP1	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)	5	UniProt NCBI
TFEB	Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35)	5	UniProt NCBI
ANKRD55	Ankyrin repeat domain-containing protein 55	5	UniProt NCBI
CDC25B	M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25B)	5	UniProt NCBI
IRS2	Insulin receptor substrate 2 (IRS-2)	5	UniProt NCBI
SPATA13	Spermatogenesis-associated protein 13 (APC-stimulated guanine nucleotide exchange factor 2) (Asef2)	5	UniProt NCBI
PLEKHG5	Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720)	5	UniProt NCBI
SPIRE2	Protein spire homolog 2 (Spir-2)	5	UniProt NCBI
SASH1	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein)	5	UniProt NCBI
MARK1	Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)	5	UniProt NCBI
SAMD4B	Protein Smaug homolog 2 (Smaug 2) (hSmaug2) (Sterile alpha motif domain-containing protein 4B) (SAM domain-containing protein 4B)	5	UniProt NCBI
FOXO3	Forkhead box protein O3 (AF6q21 protein) (Forkhead in rhabdomyosarcoma-like 1)	5	UniProt NCBI
DMTN	Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)	5	UniProt NCBI
HOMEZ	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper-containing factor)	5	UniProt NCBI
SYDE2	Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2)	4	UniProt NCBI
MARK3	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (C-TAK1) (cTAK1) (Cdc25C-associated protein kinase 1) (ELKL motif kinase 2) (EMK-2) (Protein kinase STK10) (Ser/Thr protein kinase PAR-1) (Par-1a) (Serine/threonine-protein kinase p78)	5	UniProt NCBI
LNP1	Leukemia NUP98 fusion partner 1	2	UniProt NCBI
PTOV1	Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2)	5	UniProt NCBI
MAP2K5	Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)	5	UniProt NCBI
BRAF	Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)	5	UniProt NCBI
PTPN3	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)	5	UniProt NCBI
KIAA0930	Uncharacterized protein KIAA0930	3	UniProt NCBI
YWHAB	14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]	5	UniProt NCBI
PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]	5	UniProt NCBI
CLASP1	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)	5	UniProt NCBI
SFN	14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)	5	UniProt NCBI
SPIRE1	Protein spire homolog 1 (Spir-1)	5	UniProt NCBI
FAM53B	Protein FAM53B (Protein simplet)	5	UniProt NCBI
BAD	Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)	5	UniProt NCBI
YWHAE	14-3-3 protein epsilon (14-3-3E)	5	UniProt NCBI
YWHAH	14-3-3 protein eta (Protein AS1)	5	UniProt NCBI
MAP3K2	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2)	5	UniProt NCBI
YWHAZ	14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)	5	UniProt NCBI
HDAC5	Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)	5	UniProt NCBI
CRTC1	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)	5	UniProt NCBI
FOXO1	Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead in rhabdomyosarcoma)	5	UniProt NCBI
HDAC4	Histone deacetylase 4 (HD4) (EC 3.5.1.98)	5	UniProt NCBI
FOXO4	Forkhead box protein O4 (Fork head domain transcription factor AFX1)	5	UniProt NCBI
YWHAG	14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]	5	UniProt NCBI
SRGAP2	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)	5	UniProt NCBI
A0A1X9RU27		None	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9614399	2.27122885874e-18	0.18	SFN YWHAB YWHAQ FOXO1 YWHAZ FOXO4 YWHAG A0A1X9RU27 FOXO3	Regulation of localization of FOXO transcription factors
REAC:R-HSA-111447	2.2867240525e-14	0.16	YWHAH SFN YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Activation of BAD and translocation to mitochondria
CORUM:5199	3.84147926912e-14	0.16	YWHAH YWHAB YWHAQ MAP2K5 YWHAE MAP3K3 YWHAG YWHAZ	Kinase maturation complex 1
REAC:R-HSA-9755779	9.60932546439e-13	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-2 targets host intracellular signalling and regulatory pathways
REAC:R-HSA-75035	2.07665744398e-12	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
REAC:R-HSA-9735871	7.74739646422e-12	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-1 targets host intracellular signalling and regulatory pathways
REAC:R-HSA-114452	2.00152068804e-11	0.16	YWHAH SFN YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Activation of BH3-only proteins
REAC:R-HSA-9614085	1.35152007203e-10	0.18	SFN YWHAB YWHAQ FOXO1 YWHAZ FOXO4 YWHAG A0A1X9RU27 FOXO3	FOXO-mediated transcription
REAC:R-HSA-109606	2.4324349571e-09	0.16	YWHAH SFN YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Intrinsic Pathway for Apoptosis
WP:WP5376	5.75044695569e-09	0.12	YWHAH YWHAB YWHAQ YWHAZ YWHAG YWHAE	17p13 3 YWHAE copy number variation
REAC:R-HSA-162582	5.89550760843e-08	0.52	SFN YWHAB HDAC4 YWHAE GPSM3 PLEKHG5 IRS2 FOXO1 MARK3 FOXO4 SPATA13 HDAC5 SRGAP2 YWHAH SYDE2 MAP2K5 YWHAG FOXO3 CLASP1 TIAM1 BAD YWHAQ SRGAP1 ARHGEF38 A0A1X9RU27 YWHAZ	Signal Transduction
KEGG:05203	8.24976202003e-07	0.18	YWHAH YWHAB YWHAQ HDAC4 YWHAE BAD YWHAG HDAC5 YWHAZ	Viral carcinogenesis
REAC:R-HSA-1445148	1.12996562738e-06	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Translocation of SLC2A4 (GLUT4) to the plasma membrane
REAC:R-HSA-5628897	2.95857077159e-06	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	TP53 Regulates Metabolic Genes
REAC:R-HSA-5625740	3.53068720463e-06	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	RHO GTPases activate PKNs
REAC:R-HSA-194315	5.11933758261e-06	0.28	PLEKHG5 TIAM1 SRGAP2 SFN YWHAE SYDE2 YWHAQ YWHAZ YWHAH SRGAP1 YWHAB SPATA13 YWHAG CLASP1	Signaling by Rho GTPases
WP:WP4542	5.57624325241e-06	0.1	FOXO1 A0A1X9RU27 FOXO4 YWHAQ FOXO3	Leukocyte intrinsic Hippo pathway functions
REAC:R-HSA-69473	5.84197808899e-06	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	G2/M DNA damage checkpoint
REAC:R-HSA-5674400	6.68641946031e-06	0.1	FOXO1 A0A1X9RU27 FOXO4 FOXO3 BAD	Constitutive Signaling by AKT1 E17K in Cancer
REAC:R-HSA-9716542	6.75693034692e-06	0.28	PLEKHG5 TIAM1 SRGAP2 SFN YWHAE SYDE2 YWHAQ YWHAZ YWHAH SRGAP1 YWHAB SPATA13 YWHAG CLASP1	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
REAC:R-HSA-198693	8.70451376338e-06	0.08	FOXO4 A0A1X9RU27 FOXO3 FOXO1	AKT phosphorylates targets in the nucleus
REAC:R-HSA-9692914	9.32573378486e-06	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-1-host interactions
WP:WP536	1.27994331846e-05	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Calcium regulation in cardiac cells
WP:WP179	1.63042562021e-05	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Cell cycle
KEGG:05160	2.05152400171e-05	0.14	YWHAH YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Hepatitis C
WP:WP2380	2.43903552753e-05	0.14	TIAM1 BAD MAP2K5 MAP3K2 IRS2 CRTC1 FOXO3	Brain derived neurotrophic factor BDNF signaling pathway
REAC:R-HSA-109581	2.90674793747e-05	0.16	YWHAH SFN YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Apoptosis
WP:WP289	3.75396669423e-05	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Myometrial relaxation and contraction pathways
KEGG:04110	5.38365653075e-05	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Cell cycle
REAC:R-HSA-2219528	7.44434883472e-05	0.12	FOXO4 FOXO1 IRS2 BAD A0A1X9RU27 FOXO3	PI3K/AKT Signaling in Cancer
REAC:R-HSA-5357801	9.65082888477e-05	0.16	YWHAH SFN YWHAB YWHAQ YWHAE BAD YWHAG YWHAZ	Programmed Cell Death
KEGG:04114	9.9008893148e-05	0.12	YWHAH YWHAB YWHAQ YWHAZ YWHAG YWHAE	Oocyte meiosis
GO:0005829	9.96649137868e-05	0.72	SFN YWHAB PFKFB2 PLEKHA7 IRS2 CRTC1 PI4KB HDAC4 DENND4A PLEKHG5 TIAM1 MAP3K3 FOXO1 MARK3 SPIRE1 SYDE2 SPATA13 SAMD4A SRGAP1 HOMEZ YWHAH YWHAZ SAMD4B YWHAG FOXO3 CLASP1 FOXO4 CERT1 SRGAP2 BAD YWHAQ HDAC5 MAP3K2 DMTN SASH1 YWHAE	cytosol
REAC:R-HSA-9678108	0.000104889648112	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-1 Infection
REAC:R-HSA-5663202	0.000142068260218	0.2	FOXO4 YWHAB FOXO1 HDAC5 MARK3 IRS2 BAD A0A1X9RU27 HDAC4 FOXO3	Diseases of signal transduction by growth factor receptors and second messengers
REAC:R-HSA-195258	0.000213190805392	0.18	YWHAH SFN SRGAP2 YWHAZ YWHAB YWHAQ YWHAE YWHAG CLASP1	RHO GTPase Effectors
WP:WP3915	0.000310293974791	0.12	MAP3K3 FOXO1 MAP2K5 MAP3K2 IRS2 FOXO3	Angiopoietin like protein 8 regulatory pathway
KEGG:04151	0.000367005310359	0.16	YWHAH YWHAB YWHAQ YWHAE BAD YWHAG FOXO3 YWHAZ	PI3K-Akt signaling pathway
REAC:R-HSA-69481	0.000370063200811	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	G2/M Checkpoints
WP:WP3844	0.000407161269592	0.08	FOXO4 BAD FOXO3 FOXO1	PI3K AKT mTOR signaling pathway and therapeutic opportunities in prostate cancer
WP:WP706	0.000439144624845	0.12	YWHAH YWHAB YWHAQ YWHAZ YWHAG YWHAE	Sudden infant death syndrome SIDS susceptibility pathways
REAC:R-HSA-204998	0.000485367904117	0.1	YWHAE ARHGEF38 BAD TIAM1 PLEKHG5	Cell death signalling via NRAGE, NRIF and NADE
REAC:R-HSA-9615017	0.00050489135655	0.08	FOXO4 A0A1X9RU27 FOXO3 FOXO1	FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
KEGG:04390	0.0007095825478	0.12	YWHAH YWHAB YWHAQ YWHAZ YWHAG YWHAE	Hippo signaling pathway
REAC:R-HSA-9705683	0.00113266464006	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-2-host interactions
WP:WP481	0.00115272241494	0.12	MAP3K3 FOXO1 MAP2K5 MAP3K2 IRS2 FOXO3	Insulin signaling
GO:0050815	0.00125344998193	0.08	YWHAG YWHAB YWHAE YWHAZ	phosphoserine residue binding
REAC:R-HSA-69620	0.00148403520307	0.16	YWHAH SFN YWHAZ YWHAB YWHAQ YWHAE YWHAG CLASP1	Cell Cycle Checkpoints
REAC:R-HSA-9617629	0.0015436485164	0.06	FOXO4 FOXO3 FOXO1	Regulation of FOXO transcriptional activity by acetylation
KEGG:04722	0.0016100159242	0.1	YWHAE MAP3K3 BAD FOXO3 MAP2K5	Neurotrophin signaling pathway
REAC:R-HSA-193704	0.00178757197848	0.1	YWHAE ARHGEF38 BAD TIAM1 PLEKHG5	p75 NTR receptor-mediated signalling
KEGG:04068	0.00290322341391	0.1	FOXO1 A0A1X9RU27 FOXO4 IRS2 FOXO3	FoxO signaling pathway
REAC:R-HSA-1257604	0.00425534546215	0.14	BAD FOXO1 FOXO3 IRS2 FOXO4 A0A1X9RU27 HDAC5	PIP3 activates AKT signaling
REAC:R-HSA-193648	0.00470730835833	0.08	ARHGEF38 BAD TIAM1 PLEKHG5	NRAGE signals death through JNK
REAC:R-HSA-9614657	0.00710015550882	0.06	FOXO4 FOXO3 FOXO1	FOXO-mediated transcription of cell death genes
REAC:R-HSA-9617828	0.00710015550882	0.06	FOXO4 FOXO3 FOXO1	FOXO-mediated transcription of cell cycle genes
REAC:R-HSA-1643685	0.00710806985029	0.32	FOXO4 YWHAH SFN YWHAZ YWHAB YWHAQ HDAC5 FOXO1 MARK3 IRS2 BAD YWHAG A0A1X9RU27 HDAC4 FOXO3 YWHAE	Disease
TF:M00800_1	0.0075092642461	0.58	HDAC4 PLEKHA7 IRS2 CRTC1 FAM53B YWHAH MAP3K2 SASH1 FOXO1 MARK3 SPIRE1 SPIRE2 PACS2 SAMD4A DENND4A SAMD4B PTOV1 SYDE2 FOXO3 SRGAP2 BAD YWHAQ HDAC5 CDR2L SRGAP1 MAP3K3 A0A1X9RU27 ARHGEF38 YWHAZ	Factor: AP-2; motif: GSCCSCRGGCNRNRNN; match class: 1
REAC:R-HSA-212436	0.00987236482155	0.26	YWHAH SFN YWHAB YWHAQ HDAC5 FOXO1 YWHAE FOXO4 YWHAG A0A1X9RU27 HDAC4 FOXO3 YWHAZ	Generic Transcription Pathway
REAC:R-HSA-9006925	0.0106055597874	0.14	BAD FOXO1 FOXO3 IRS2 FOXO4 A0A1X9RU27 HDAC5	Intracellular signaling by second messengers
REAC:R-HSA-9694516	0.0128226348107	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	SARS-CoV-2 Infection
WP:WP437	0.0168138359262	0.1	FOXO1 MAP3K3 FOXO4 MAP2K5 MAP3K2	EGF EGFR signaling pathway
WP:WP2261	0.0178638341925	0.08	FOXO1 FOXO4 FOXO3 MAP2K5	Glioblastoma signaling pathways
REAC:R-HSA-73887	0.0246248577709	0.1	YWHAE ARHGEF38 BAD TIAM1 PLEKHG5	Death Receptor Signaling
REAC:R-HSA-73857	0.0308727090578	0.26	YWHAH SFN YWHAB YWHAQ HDAC5 FOXO1 YWHAE FOXO4 YWHAG A0A1X9RU27 HDAC4 FOXO3 YWHAZ	RNA Polymerase II Transcription
GO:0035556	0.0365345286996	0.4	PLEKHG5 SASH1 TIAM1 SRGAP2 SFN YWHAE MAP3K3 MAP2K5 BAD FOXO1 MARK3 YWHAZ MAP3K2 DMTN PI4KB YWHAG SPATA13 SYDE2 MARK1 DENND4A	intracellular signal transduction
WP:WP3888	0.0391339996282	0.14	FOXO4 FOXO1 FOXO3 YWHAE HDAC4 HDAC5 SPIRE1	VEGFA VEGFR2 signaling
KEGG:04152	0.0424359141788	0.08	FOXO1 PFKFB2 IRS2 FOXO3	AMPK signaling pathway
REAC:R-HSA-3700989	0.0490485895949	0.14	YWHAH SFN YWHAB YWHAQ YWHAE YWHAG YWHAZ	Transcriptional Regulation by TP53

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
YWHAZ	YWHAB	1.0	0.915
YWHAG	YWHAH	1.0	0.802
YWHAG	YWHAB	1.0	0.913
YWHAZ	YWHAH	1.0	0.724
YWHAH	YWHAB	1.0	0.77
YWHAG	YWHAE	1.0	0.782
YWHAH	YWHAE	1.0	0.534
YWHAZ	YWHAE	1.0	0.696
YWHAB	YWHAE	1.0	0.704
YWHAZ	YWHAG	1.0	0.864
YWHAQ	YWHAB	0.999	0.572	structurally_consistent (dimer)
YWHAH	SAMD4A	0.999	0.412630536131
SFN	SMTNL2	0.999		structurally_consistent (dimer)
YWHAZ	YWHAQ	0.999	0.662	structurally_consistent (dimer)
YWHAG	FAM53B	0.999
YWHAG	YWHAQ	0.999	0.77	structurally_consistent (dimer)
YWHAQ	YWHAH	0.999	0.526	structurally_consistent (dimer)
YWHAH	FAM53B	0.999
YWHAG	SAMD4A	0.999	0.708
YWHAQ	YWHAE	0.999	0.944	structurally_consistent (dimer)
SAMD4A	YWHAE	0.998	0.487119479865
FAM53B	YWHAB	0.998
YWHAG	SFN	0.998	0.644	structurally_consistent (dimer)
YWHAZ	SMTNL2	0.998
HDAC4	YWHAB	0.997	0.394
SMTNL2	YWHAH	0.997
YWHAZ	TFEB	0.997	0.622
SAMD4A	YWHAB	0.997	0.301325581395
SAMD4B	YWHAG	0.997	0.3265
HDAC4	YWHAH	0.997	0.39
YWHAQ	SFN	0.997	0.51	structurally_consistent (dimer)
SMTNL2	YWHAB	0.997		mutually_exclusive (P27348)
YWHAH	IRS2	0.996	0.44925
HDAC4	YWHAG	0.996	0.508
TFEB	YWHAE	0.996	0.426583333333
YWHAG	SMTNL2	0.996		mutually_exclusive (P27348)
YWHAH	MARK3	0.996	0.172
SAMD4B	YWHAE	0.996	0.224
SAMD4B	YWHAB	0.996	0.202722222222
YWHAG	IRS2	0.995	0.532
YWHAG	MARK3	0.995	0.202
YWHAQ	FAM53B	0.995
YWHAZ	SFN	0.995	0.732	structurally_consistent (dimer)
YWHAQ	SMTNL2	0.995		structurally_consistent (dimer)
MAP3K2	MAP2K5	0.995	0.192	structurally_consistent (dimer)
YWHAH	TFEB	0.995	0.340814070352
HDAC4	YWHAQ	0.995	0.394	structurally_consistent (dimer)
YWHAG	TFEB	0.995	0.578608695652
FAM53B	YWHAE	0.994
CLASP1	YWHAH	0.994	0.268
SFN	YWHAB	0.994	0.716	structurally_consistent (dimer)
MAP3K3	MAP2K5	0.994	0.082	structurally_consistent (dimer)
SMTNL2	YWHAE	0.993		mutually_exclusive (P27348)
YWHAG	MARK1	0.993	0.39
YWHAQ	MAP3K2	0.993	0.284	structurally_consistent (dimer)
YWHAH	BRAF	0.993	0.382
YWHAQ	TFEB	0.992	0.451702702703
YWHAG	MAP3K2	0.992	0.393416666667
MAP3K3	YWHAG	0.992	0.574538095238
TFEB	YWHAB	0.992	0.3775
MARK1	YWHAH	0.992	0.3034875
YWHAG	FOXO3	0.991	0.444
SFN	YWHAH	0.991	0.536	structurally_consistent (dimer)
BRAF	YWHAB	0.991	0.396
YWHAG	BRAF	0.991	0.482
PLEKHA7	YWHAG	0.991	0.5056
YWHAG	PFKFB2	0.991	0.31	mutually_exclusive (P27348)
MARK3	YWHAB	0.991	0.173041666667
PFKFB2	YWHAQ	0.991	0.374	structurally_consistent (dimer)
ANKRD55	YWHAQ	0.99
YWHAQ	BRAF	0.99	0.424	structurally_consistent (dimer)
CRTC1	YWHAG	0.99	0.37136
CDC25B	YWHAH	0.99	0.33
SFN	TFEB	0.99	0.337262626263
CDR2L	SFN	0.99	0.544
YWHAG	CDC25B	0.99	0.346
PFKFB2	YWHAB	0.99	0.314	mutually_exclusive (P27348)
SFN	BAD	0.989	0.136	structurally_consistent (dimer)
MAP3K3	YWHAQ	0.989	0.558
HDAC4	PTOV1	0.989	0.13
SFN	FAM53B	0.989
FOXO3	YWHAH	0.988	0.24
CDR2L	YWHAQ	0.988	0.554933333333
YWHAQ	DMTN	0.987	0.572	structurally_consistent (dimer)
YWHAZ	HDAC4	0.987	0.46747624264
SPATA13	YWHAB	0.987	0.237693851718
YWHAZ	BRAF	0.987	0.588666666667
IRS2	BRAF	0.987	0.11
YWHAG	TIAM1	0.986	0.534
YWHAQ	SAMD4A	0.986	0.533789595376
ANKRD55	YWHAB	0.986
MAP3K3	MAP3K2	0.986	0.16	mutually_exclusive (Q13163)
LNP1	YWHAE	0.986
SRGAP2	YWHAH	0.986	0.166
CDR2L	YWHAE	0.986	0.442315789474
YWHAG	DMTN	0.985	0.701020594966
YWHAZ	LNP1	0.985
PACS2	YWHAG	0.985	0.594
PFKFB2	YWHAH	0.985	0.332	mutually_exclusive (P27348)
MAP3K2	YWHAH	0.985	0.308090909091
YWHAG	BAD	0.985	0.508
SFN	YWHAE	0.984	0.643333333333	structurally_consistent (dimer)
YWHAH	LNP1	0.984
IRS2	YWHAE	0.984	0.460909090909
DMTN	YWHAE	0.984	0.189733333333
YWHAG	DENND4A	0.984	0.488	mutually_exclusive (P27348)
SRGAP2	YWHAG	0.984	0.454
CDR2L	YWHAB	0.984	0.430744186047
PI4KB	YWHAG	0.983	0.24
YWHAG	SPIRE1	0.983	0.3
PACS2	YWHAH	0.983	0.331910666153
IRS2	YWHAB	0.983	0.38679787234
CDC25B	YWHAB	0.983	0.38
YWHAZ	PFKFB2	0.983	0.498996309963	mutually_exclusive (P27348)
IRS2	PTOV1	0.983	0.098
PTOV1	YWHAB	0.982	0.30004
YWHAH	BAD	0.982	0.142
YWHAZ	GPSM3	0.982	0.314	mutually_exclusive (P27348)
PACS2	YWHAQ	0.982	0.6354
YWHAG	LNP1	0.982
YWHAZ	CDC25B	0.982	0.57
HDAC4	IRS2	0.981	0.140666666667
YWHAQ	LNP1	0.981
GPSM3	YWHAQ	0.981	0.506	structurally_consistent (dimer)
YWHAG	FOXO1	0.981	0.445171521036	mutually_exclusive (P27348)
YWHAH	KIAA0930	0.981	0.246666666667
YWHAQ	BAD	0.981	0.404	structurally_consistent (dimer)
CLASP1	YWHAB	0.98	0.282
SRGAP1	SRGAP2	0.98	0.202
LNP1	YWHAB	0.98
YWHAG	PTPN3	0.979	0.4224
BAD	YWHAB	0.979	0.12361779661
YWHAG	PTOV1	0.979	0.365892
SPIRE2	YWHAB	0.979
MARK1	YWHAQ	0.979	0.322	structurally_consistent (dimer)
YWHAQ	CDC25B	0.978	0.39	structurally_consistent (dimer)
YWHAZ	PLEKHG5	0.978
SFN	MAP3K2	0.978	0.304
SAMD4B	SAMD4A	0.978	0.068
YWHAZ	SPIRE1	0.977	0.294
YWHAQ	SPIRE1	0.977	0.276
YWHAQ	SPATA13	0.976	0.304
YWHAG	KIAA0930	0.976	0.325649224535
HDAC5	YWHAB	0.976	0.4	mutually_exclusive (P31947)
SRGAP1	YWHAG	0.976	0.49
SRGAP1	YWHAH	0.976	0.351043478261
MAP3K3	YWHAH	0.976	0.534956989247
YWHAQ	IRS2	0.976	0.488
PTPN3	YWHAB	0.975	0.36
BRAF	YWHAE	0.975	0.432
YWHAQ	PTPN3	0.975	0.580166666667
YWHAH	SPIRE1	0.975	0.222660377358
YWHAG	SPATA13	0.975	0.382862588235
YWHAH	DENND4A	0.975	0.28	mutually_exclusive (P27348)
SRGAP2	YWHAB	0.974	0.1955
SFN	KIAA0930	0.974	0.222	structurally_consistent (dimer)
DMTN	YWHAB	0.974	0.369648247322
YWHAZ	DMTN	0.974	0.451766666667
YWHAZ	SAMD4A	0.974	0.521171428571
SYDE2	YWHAB	0.974
SASH1	YWHAH	0.974	0.292
SPIRE1	YWHAB	0.973	0.204
YWHAH	FOXO1	0.973	0.432967741935	mutually_exclusive (P27348)
ARHGEF38	YWHAE	0.973
MAP3K3	SFN	0.973	0.387666666667
YWHAQ	MARK3	0.973	0.16
YWHAZ	MAP3K2	0.973	0.384619047619
MAP3K2	YWHAE	0.972	0.440862038381
FOXO1	YWHAB	0.972	0.465147618658	mutually_exclusive (P27348)
YWHAH	TIAM1	0.971	0.236
YWHAG	SASH1	0.971	0.498
CRTC1	YWHAH	0.971	0.153561845286	mutually_exclusive (P27348)
CDR2L	YWHAH	0.971	0.369797202797
YWHAH	SPATA13	0.971	0.252554778555
YWHAZ	CDR2L	0.97	0.574
YWHAH	PTOV1	0.97	0.388998934375
YWHAZ	BAD	0.97	0.0881428571429
YWHAQ	FOXO1	0.97	0.508	structurally_consistent (dimer)
HDAC4	YWHAE	0.969	0.564114834206
YWHAZ	ANKRD55	0.969
YWHAH	PTPN3	0.969	0.319
KIAA0930	YWHAB	0.969	0.24373134257
YWHAZ	KIAA0930	0.968	0.330909090909
CRTC1	YWHAB	0.967	0.15486779661
CERT1	MARK3	0.966	0.048
MARK1	YWHAB	0.966	0.268711538462
YWHAZ	FAM53B	0.966
DMTN	SFN	0.966	0.5104
YWHAZ	SPATA13	0.966	0.439017094017
CERT1	MARK1	0.965	0.076
YWHAG	SPIRE2	0.965
SYDE2	YWHAH	0.965
YWHAG	HDAC5	0.964	0.405777777778
SPIRE2	YWHAH	0.964
SFN	LNP1	0.964
YWHAZ	SAMD4B	0.964	0.196
SAMD4B	YWHAH	0.963	0.136
YWHAQ	PTOV1	0.963	0.364
GPSM3	YWHAB	0.963	0.266
HOMEZ	YWHAB	0.963	0.358	mutually_exclusive (P27348)
PI4KB	YWHAH	0.962	0.2315
ANKRD55	YWHAE	0.962
YWHAH	HDAC5	0.961	0.290709677419
PACS2	YWHAB	0.96	0.376
YWHAG	HOMEZ	0.959	0.630855106888	mutually_exclusive (P27348)
TIAM1	YWHAB	0.958	0.300446428571
SFN	BRAF	0.957	0.266
PLEKHA7	YWHAB	0.957	0.263648247322
DENND4A	YWHAB	0.957	0.314	mutually_exclusive (P27348)
CLASP1	ARHGEF38	0.957
PLEKHA7	YWHAH	0.957	0.194
YWHAQ	TIAM1	0.956	0.386
SRGAP1	YWHAB	0.955	0.304504885649
MAP3K3	YWHAZ	0.954	0.576
YWHAQ	FOXO4	0.954		mutually_exclusive (P31947)
YWHAZ	PI4KB	0.954	0.208
YWHAH	FOXO4	0.954		mutually_exclusive (P31947)
YWHAZ	PTOV1	0.953	0.472703862661
YWHAQ	DENND4A	0.952	0.338	structurally_consistent (dimer)
YWHAQ	KIAA0930	0.952	0.292436781609	structurally_consistent (dimer)
YWHAZ	HOMEZ	0.952	0.39464516129	mutually_exclusive (P27348)
YWHAG	CLASP1	0.951	0.346055555556
PLEKHG5	YWHAH	0.951
PLEKHG5	YWHAG	0.95
SRGAP1	YWHAQ	0.95	0.498
FOXO4	YWHAB	0.949
GPSM3	SFN	0.949	0.158
YWHAG	CDR2L	0.948	0.55
PI4KB	YWHAB	0.948	0.224714589666
YWHAZ	MARK3	0.948	0.288909090909
YWHAZ	FOXO1	0.948	0.638	mutually_exclusive (P27348)
SPATA13	YWHAE	0.946	0.392366471735
CDC25B	YWHAE	0.944	0.503
PLEKHG5	YWHAE	0.943
YWHAZ	IRS2	0.941	0.477761904762
YWHAG	ANKRD55	0.937
YWHAG	FOXO4	0.937
SRGAP2	YWHAZ	0.936	0.576
YWHAZ	DENND4A	0.936	0.320166666667	mutually_exclusive (P27348)
ANKRD55	YWHAH	0.936
MAP3K2	YWHAB	0.936	0.232
DMTN	YWHAH	0.935	0.366116351733
BAD	YWHAE	0.932	0.198
GPSM3	YWHAE	0.932	0.284
CRTC1	YWHAQ	0.93	0.208	structurally_consistent (dimer)
GPSM3	YWHAG	0.925	0.474
SYDE2	YWHAQ	0.924
PACS2	YWHAZ	0.921	0.544106400665
PI4KB	YWHAQ	0.921	0.246
SYDE2	YWHAG	0.918
HOMEZ	YWHAH	0.917	0.328	mutually_exclusive (P27348)
MAP3K3	YWHAB	0.916	0.336264388826	mutually_exclusive (Q13163)
GPSM3	YWHAH	0.911	0.316	mutually_exclusive (P27348)
YWHAQ	FOXO3	0.911	0.446
PLEKHG5	YWHAQ	0.909
YWHAQ	HDAC5	0.903	0.4575
YWHAQ	SASH1	0.903	0.326	structurally_consistent (dimer)
PLEKHG5	YWHAB	0.902
SASH1	YWHAB	0.901	0.328
PLEKHG5	SFN	0.901
SRGAP2	YWHAQ	0.9	0.478	structurally_consistent (dimer)
FOXO3	YWHAB	0.899	0.382
SPIRE2	BRAF	0.898
YWHAZ	MARK1	0.888	0.318266666667
BRAF	MARK3	0.88	0.138
YWHAZ	CRTC1	0.876	0.251575264844	mutually_exclusive (P27348)
HOMEZ	YWHAQ	0.87	0.484	structurally_consistent (dimer)
KIAA0930	YWHAE	0.865	0.344027324121
YWHAQ	SPIRE2	0.854
SAMD4B	YWHAQ	0.853	0.346
SFN	SPATA13	0.843	0.214875
SPIRE2	IRS2	0.838
SFN	SAMD4A	0.835	0.356
YWHAZ	HDAC5	0.831	0.513774193548
YWHAG	ARHGEF38	0.829
YWHAZ	PTPN3	0.802	0.506
YWHAZ	SYDE2	0.782
SPIRE2	SPIRE1	0.781
YWHAZ	PLEKHA7	0.777	0.351173076923
PTOV1	YWHAE	0.767	0.354133333333
YWHAZ	CLASP1	0.754	0.274
SAMD4A	MARK3	0.723	0.09
PLEKHA7	YWHAQ	0.723	0.417142857143
YWHAZ	FOXO3	0.697	0.573297297297
IRS2	MARK3	0.695	0.116
MARK1	MARK3	0.683	0.152
SRGAP1	YWHAZ	0.672	0.308655751956
MAP3K3	FOXO1	0.665	0.11
SPIRE2	MARK3	0.661
MAP3K3	FOXO3	0.646	0.108
TFEB	IRS2	0.617	0.168
PACS2	YWHAE	0.611	0.501679479865
ARHGEF38	YWHAB	0.607
PLEKHA7	SPIRE1	0.605	0.092
CDC25B	TFEB	0.605	0.112
MARK1	TFEB	0.605	0.112
TFEB	BAD	0.605	0.08
PLEKHA7	PFKFB2	0.605	0.044
CDC25B	FOXO3	0.605	0.138
CDC25B	FAM53B	0.605
PFKFB2	SPIRE1	0.605	0.042
MAP3K3	CDC25B	0.582	0.078
MAP3K3	BAD	0.582	0.058
SFN	CDC25B	0.577	0.242
TFEB	FOXO1	0.576	0.15
YWHAZ	ARHGEF38	0.571
DENND4A	IRS2	0.566	0.08
FOXO3	TFEB	0.566	0.046
IRS2	FOXO1	0.564	0.09
FOXO3	BAD	0.561	0.132
FAM53B	BAD	0.561
PI4KB	FOXO3	0.556	0.07
SAMD4B	FOXO1	0.549	0.108
SAMD4B	IRS2	0.548	0.1
CRTC1	FOXO3	0.543	0.208
HDAC4	TIAM1	0.54	0.218
HDAC4	CRTC1	0.54	0.188
HDAC4	HDAC5	0.54	0.158
HDAC4	MAP3K2	0.54	0.082
HDAC4	FAM53B	0.54
CDC25B	SPIRE1	0.54	0.132
HDAC4	FOXO3	0.54	0.168
HDAC4	TFEB	0.54	0.094
CLASP1	CDC25B	0.539	0.07
CLASP1	TIAM1	0.539	0.092
PFKFB2	KIAA0930	0.539	0.092	mutually_exclusive (P27348)
SASH1	TIAM1	0.539	0.22
PI4KB	MAP3K2	0.539	0.166
PLEKHA7	BAD	0.539	0.088
SRGAP2	BAD	0.539	0.1	mutually_exclusive (P27348)
SAMD4B	SASH1	0.539	0.058
SPIRE1	BAD	0.539	0.124
PI4KB	CDC25B	0.539	0.118
KIAA0930	SPIRE1	0.539	0.05
SRGAP2	PFKFB2	0.539	0.038	mutually_exclusive (P27348)
CLASP1	MAP3K2	0.539	0.106
PI4KB	SPIRE1	0.539	0.086
KIAA0930	FAM53B	0.539
CLASP1	IRS2	0.539	0.156
CDC25B	DENND4A	0.539	0.108
SRGAP2	CDC25B	0.539	0.0884395604396	mutually_exclusive (P27348)
PI4KB	PFKFB2	0.539	0.058
PFKFB2	SASH1	0.539	0.066	mutually_exclusive (P27348)
SASH1	FOXO3	0.539	0.126
SASH1	FOXO1	0.539	0.202	mutually_exclusive (P27348)
PLEKHA7	CDC25B	0.539	0.126
HDAC4	SASH1	0.539	0.09
HDAC4	CLASP1	0.539	0.13
TFEB	BRAF	0.539	0.118
SASH1	SPIRE1	0.539	0.142
PLEKHA7	DENND4A	0.539	0.084
CLASP1	KIAA0930	0.539	0.108
CLASP1	FAM53B	0.539
PFKFB2	CLASP1	0.539	0.082
CLASP1	SPIRE1	0.539	0.102
TFEB	KIAA0930	0.539	0.09
SPIRE2	SASH1	0.539
SRGAP2	SPIRE1	0.539	0.084
PI4KB	FAM53B	0.539
PLEKHA7	KIAA0930	0.539	0.058
SASH1	BAD	0.539	0.048	mutually_exclusive (P27348)
CLASP1	TFEB	0.539	0.082
KIAA0930	BAD	0.539	0.064
SASH1	SAMD4A	0.539	0.086
SASH1	TFEB	0.539	0.092
CLASP1	BAD	0.539	0.088
PLEKHA7	PI4KB	0.539	0.044
PFKFB2	CDC25B	0.539	0.054	mutually_exclusive (P27348)
CDC25B	SASH1	0.539	0.07	mutually_exclusive (P27348)
CDC25B	BAD	0.539	0.126	mutually_exclusive (P27348)
CDC25B	KIAA0930	0.539	0.128	mutually_exclusive (P27348)
SASH1	IRS2	0.539	0.1
PI4KB	IRS2	0.539	0.076
PLEKHA7	SASH1	0.539	0.11
PFKFB2	DENND4A	0.539	0.028	mutually_exclusive (P27348)
CRTC1	CLASP1	0.539	0.124
PI4KB	BAD	0.539	0.064
SASH1	HDAC5	0.539	0.132
PLEKHA7	CLASP1	0.539	0.072
FOXO3	KIAA0930	0.539	0.08
MAP3K2	SASH1	0.539	0.074	mutually_exclusive (P27348)
PI4KB	CRTC1	0.539	0.112
SASH1	FAM53B	0.539
PI4KB	TFEB	0.539	0.078
PFKFB2	BAD	0.539	0.068	mutually_exclusive (P27348)
PI4KB	TIAM1	0.539	0.118
CRTC1	SASH1	0.539	0.1	mutually_exclusive (P27348)
MARK1	FOXO3	0.539	0.144
MARK1	FAM53B	0.539
CRTC1	IRS2	0.538	0.144
CDC25B	TIAM1	0.534	0.162
TIAM1	IRS2	0.534	0.168
MAP3K2	TFEB	0.534	0.09
TFEB	FAM53B	0.534
HDAC4	PI4KB	0.534	0.108
TFEB	TIAM1	0.534	0.076
IRS2	KIAA0930	0.534	0.134
PFKFB2	TFEB	0.534	0.108
PFKFB2	MAP3K2	0.534	0.076	mutually_exclusive (P27348)
IRS2	BAD	0.534	0.098
PLEKHA7	HDAC5	0.534	0.086
CRTC1	BAD	0.534	0.214	mutually_exclusive (P27348)
MAP3K2	TIAM1	0.534	0.096
IRS2	SPIRE1	0.534	0.08
CRTC1	PFKFB2	0.534	0.04	mutually_exclusive (P27348)
TIAM1	DENND4A	0.534	0.155
IRS2	FAM53B	0.534
TFEB	SPIRE1	0.534	0.106
HDAC4	CDC25B	0.534	0.104
MAP3K2	KIAA0930	0.534	0.156	mutually_exclusive (P27348)
CDC25B	HDAC5	0.534	0.088
CRTC1	TIAM1	0.534	0.156
SRGAP2	TIAM1	0.534	0.246
TIAM1	BAD	0.534	0.126
TIAM1	HDAC5	0.534	0.102
HDAC4	PFKFB2	0.534	0.046	mutually_exclusive (P27348)
CRTC1	CDC25B	0.534	0.122	mutually_exclusive (P27348)
MAP3K2	CDC25B	0.534	0.154	mutually_exclusive (P27348)
PFKFB2	FOXO3	0.534	0.076
MARK1	IRS2	0.534	0.12
SRGAP2	MAP3K2	0.534	0.084	mutually_exclusive (P27348)
TIAM1	SPIRE1	0.534	0.202
PFKFB2	TIAM1	0.534	0.124
PLEKHA7	FAM53B	0.534
HDAC4	BAD	0.534	0.08
SRGAP2	HDAC4	0.534	0.128
CRTC1	MAP3K2	0.534	0.09	mutually_exclusive (P27348)
MAP3K2	DENND4A	0.534	0.064
MAP3K2	BAD	0.534	0.056	mutually_exclusive (P27348)
MAP3K2	FOXO3	0.534	0.146
HDAC4	SPIRE1	0.534	0.204
MAP3K2	SPIRE1	0.534	0.08
CDC25B	IRS2	0.534	0.118
PFKFB2	FAM53B	0.534
HDAC4	DENND4A	0.534	0.082
MAP3K2	FAM53B	0.534
MAP3K2	IRS2	0.534	0.078
FOXO3	TIAM1	0.534	0.218
HDAC4	PLEKHA7	0.534	0.13
CRTC1	SPIRE1	0.534	0.108
HDAC4	KIAA0930	0.534	0.078
CRTC1	KIAA0930	0.534	0.066	mutually_exclusive (P27348)
TIAM1	FAM53B	0.534
TIAM1	KIAA0930	0.534	0.04
SPIRE1	FAM53B	0.534
PLEKHA7	CRTC1	0.534	0.088
PLEKHA7	TFEB	0.534	0.092
PLEKHA7	MAP3K2	0.534	0.048
PLEKHA7	FOXO3	0.534	0.106
PFKFB2	IRS2	0.534	0.076
SRGAP2	FOXO1	0.528	0.218133333333	mutually_exclusive (P27348)
ARHGEF38	YWHAQ	0.527
MAP3K3	HDAC4	0.517	0.144
SRGAP2	FAM53B	0.516
DENND4A	FAM53B	0.516
MAP3K3	CLASP1	0.516	0.152
MAP3K3	KIAA0930	0.516	0.072
MAP3K3	PI4KB	0.516	0.134
MAP3K3	SASH1	0.516	0.072
SRGAP2	IRS2	0.513	0.216
MAP3K3	IRS2	0.511	0.068
MAP3K3	PLEKHA7	0.511	0.094
MAP3K3	SPIRE1	0.511	0.078
MAP3K3	PFKFB2	0.511	0.102
CRTC1	FAM53B	0.511
MAP3K3	TFEB	0.511	0.112
MAP3K3	TIAM1	0.511	0.148
IRS2	PTPN3	0.504	0.126
CRTC1	TFEB	0.5	0.116
MAP3K3	YWHAE	0.497	0.609023076923
MARK1	SAMD4A	0.496	0.088
MAP3K2	FOXO1	0.496	0.168	mutually_exclusive (P27348)
TIAM1	FOXO1	0.496	0.16
HDAC4	FOXO1	0.496	0.168
TFEB	DENND4A	0.495	0.126
CLASP1	FOXO3	0.495	0.164
BRAF	BAD	0.494	0.134	mutually_exclusive (P27348)
MAP3K2	BRAF	0.494	0.156	mutually_exclusive (P27348)
PFKFB2	BRAF	0.494	0.084	mutually_exclusive (P27348)
PLEKHA7	BRAF	0.494	0.14
CLASP1	HDAC5	0.494	0.146
MARK1	BAD	0.494	0.092	mutually_exclusive (P27348)
MARK1	CDC25B	0.494	0.08
MARK1	KIAA0930	0.494	0.054
MARK1	SPIRE1	0.494	0.12
HDAC4	MARK3	0.494	0.144
TIAM1	BRAF	0.494	0.126
CLASP1	FOXO1	0.494	0.116
BRAF	SPIRE1	0.494	0.076
CDC25B	BRAF	0.494	0.106	mutually_exclusive (P27348)
MARK1	PFKFB2	0.494	0.09	mutually_exclusive (P27348)
PLEKHA7	MARK1	0.494	0.082
MAP3K2	MARK3	0.494	0.078
YWHAZ	TIAM1	0.493	0.42677992278
FOXO3	IRS2	0.491	0.09
TFEB	HDAC5	0.491	0.114
MAP3K2	HDAC5	0.489	0.164
BAD	FOXO1	0.489	0.09	mutually_exclusive (P27348)
BAD	HDAC5	0.489	0.104	mutually_exclusive (P31947)
HDAC4	BRAF	0.489	0.0952
PFKFB2	HDAC5	0.489	0.062
PI4KB	FOXO1	0.489	0.106
CDC25B	FOXO1	0.489	0.162	mutually_exclusive (P27348)
MARK1	MAP3K2	0.489	0.13
SPIRE1	HDAC5	0.489	0.17
FOXO3	SPIRE1	0.489	0.178
SPIRE1	FOXO1	0.489	0.158
KIAA0930	FOXO1	0.489	0.102	mutually_exclusive (P27348)
PFKFB2	FOXO1	0.489	0.102	mutually_exclusive (P27348)
MARK1	TIAM1	0.489	0.124
HDAC4	MARK1	0.489	0.144
PLEKHA7	FOXO1	0.489	0.112
PI4KB	HDAC5	0.482	0.126
SASH1	MARK3	0.48	0.111166666667
SAMD4A	FAM53B	0.48
TIAM1	SAMD4A	0.48	0.12
SAMD4A	KIAA0930	0.48	0.048
SAMD4B	BAD	0.48	0.078
PLEKHA7	SPIRE2	0.48
HDAC4	SAMD4A	0.48	0.124
SPIRE2	SAMD4A	0.48
PI4KB	KIAA0930	0.48	0.15
SAMD4B	SPIRE2	0.48
CLASP1	SPIRE2	0.48
CRTC1	SAMD4A	0.48	0.082
SPIRE2	TIAM1	0.48
PI4KB	SPIRE2	0.48
SAMD4B	TIAM1	0.48	0.132
PFKFB2	SAMD4A	0.48	0.07
SPIRE2	BAD	0.48
SASH1	KIAA0930	0.48	0.066	mutually_exclusive (P27348)
HDAC4	SPIRE2	0.48
SPIRE2	MAP3K2	0.48
PI4KB	SASH1	0.48	0.064
SPIRE2	TFEB	0.48
PI4KB	SAMD4A	0.48	0.098
SASH1	BRAF	0.48	0.062	mutually_exclusive (P27348)
SAMD4B	PFKFB2	0.48	0.04
SAMD4A	SPIRE1	0.48	0.148
SAMD4B	SPIRE1	0.48	0.07
PI4KB	DENND4A	0.48	0.134
SAMD4B	KIAA0930	0.48	0.052
SASH1	DENND4A	0.48	0.076
SAMD4A	BRAF	0.48	0.08
MAP3K2	SAMD4A	0.48	0.098
TFEB	SAMD4A	0.48	0.102
PLEKHA7	SAMD4A	0.48	0.082
PFKFB2	SPIRE2	0.48
SAMD4A	BAD	0.48	0.112
FOXO3	SAMD4A	0.48	0.128
CDC25B	SAMD4A	0.48	0.08
SPIRE2	KIAA0930	0.48
SAMD4B	MAP3K2	0.48	0.09
CLASP1	DENND4A	0.48	0.048
DENND4A	SPIRE1	0.48	0.132
CLASP1	SASH1	0.48	0.048
SRGAP2	KIAA0930	0.48	0.074	mutually_exclusive (P27348)
SAMD4B	CDC25B	0.48	0.106
DENND4A	KIAA0930	0.48	0.142
PI4KB	CLASP1	0.48	0.14
CLASP1	SAMD4A	0.48	0.154
SRGAP2	SASH1	0.48	0.104	mutually_exclusive (P27348)
SPIRE2	CDC25B	0.48
SAMD4B	TFEB	0.48	0.096
CRTC1	SAMD4B	0.48	0.03
SAMD4A	HDAC5	0.48	0.138
SAMD4B	FAM53B	0.48
MARK1	SASH1	0.48	0.09
SRGAP2	PI4KB	0.48	0.15
PI4KB	SAMD4B	0.48	0.156
DENND4A	BAD	0.48	0.058
SAMD4A	FOXO1	0.48	0.154
HDAC4	SAMD4B	0.48	0.082
GPSM3	MARK1	0.479		mutually_exclusive (P27348)
KIAA0930	HDAC5	0.477	0.132	mutually_exclusive (P31947)
SAMD4A	IRS2	0.476	0.196
FAM53B	FOXO1	0.472
BRAF	HDAC5	0.471	0.206
BRAF	FAM53B	0.471
CRTC1	BRAF	0.471	0.072	mutually_exclusive (P27348)
FOXO3	BRAF	0.471	0.126
SRGAP1	YWHAE	0.47	0.335433138402
SRGAP2	FOXO3	0.469	0.208
CRTC1	DENND4A	0.467	0.056	mutually_exclusive (P27348)
SRGAP2	BRAF	0.466	0.144	mutually_exclusive (P27348)
MARK1	HDAC5	0.466	0.142
FOXO3	FAM53B	0.466
CRTC1	MARK1	0.466	0.098	mutually_exclusive (P27348)
MARK1	FOXO1	0.466	0.138	mutually_exclusive (P27348)
FAM53B	HDAC5	0.466
BRAF	FOXO1	0.466	0.158	mutually_exclusive (P27348)
DENND4A	BRAF	0.466	0.13	mutually_exclusive (P27348)
FOXO3	HDAC5	0.463	0.348
DENND4A	SAMD4A	0.461	0.144
HDAC5	FOXO1	0.46	0.15
CRTC1	FOXO1	0.459	0.092	mutually_exclusive (P27348)
SPIRE2	DENND4A	0.457
SPIRE2	HDAC5	0.457
SPIRE2	FOXO1	0.457
CRTC1	SPIRE2	0.457
SRGAP2	SPIRE2	0.457
MAP3K3	SAMD4B	0.457	0.094
SPIRE2	FAM53B	0.457
SPIRE2	FOXO3	0.457
MAP3K3	SAMD4A	0.457	0.154
MARK1	SPIRE2	0.457
PLEKHA7	PTPN3	0.456	0.138
CRTC1	HDAC5	0.454	0.112
DENND4A	FOXO1	0.454	0.076	mutually_exclusive (P27348)
YWHAZ	FOXO4	0.449		mutually_exclusive (P31947)
PTPN3	YWHAE	0.448	0.454925925926
PI4KB	SMTNL2	0.447
SMTNL2	MARK3	0.447		mutually_exclusive (P31947)
SYDE2	SFN	0.447
SFN	TIAM1	0.447	0.368548387097
SFN	IRS2	0.447	0.336
SFN	HDAC5	0.447	0.274417508418	structurally_consistent (dimer)
PTOV1	HDAC5	0.447	0.14	mutually_exclusive (P31947)
MARK1	PTOV1	0.447	0.128
SRGAP2	PTOV1	0.447	0.176
CRTC1	PTOV1	0.447	0.094
SYDE2	PTOV1	0.447
TFEB	PTOV1	0.447	0.09
SFN	FOXO1	0.447	0.546	mutually_exclusive (P27348)
MAP3K3	PTOV1	0.447	0.074
SASH1	PTOV1	0.447	0.08
PFKFB2	PTOV1	0.447	0.106
PTOV1	KIAA0930	0.447	0.094	mutually_exclusive (P31947)
SFN	PTPN3	0.447	0.32
PTOV1	SPIRE1	0.447	0.138
PTOV1	FAM53B	0.447
SYDE2	YWHAE	0.447
SRGAP1	SFN	0.447	0.244685714286
PTOV1	BRAF	0.447	0.062
PTOV1	PTPN3	0.447	0.108
PLEKHA7	PTOV1	0.447	0.142
PTOV1	BAD	0.447	0.094	mutually_exclusive (P31947)
SMTNL2	DENND4A	0.447
PFKFB2	SFN	0.447	0.432461538462	mutually_exclusive (P27348)
PACS2	SFN	0.447	0.314
PACS2	PTOV1	0.447	0.104
MAP3K2	PTOV1	0.447	0.064
CDC25B	PTOV1	0.447	0.088
HDAC4	SFN	0.447	0.394461139896
TIAM1	PTOV1	0.447	0.114
CRTC1	SFN	0.447	0.171767901235	mutually_exclusive (P27348)
SRGAP2	SMTNL2	0.447		mutually_exclusive (P27348)
HOMEZ	PTOV1	0.447	0.096
SFN	SASH1	0.447	0.312
SFN	FOXO3	0.447	0.452
FOXO3	PTOV1	0.447	0.116
SRGAP2	CLASP1	0.438	0.146405594406
MARK1	CLASP1	0.436	0.098
PFKFB2	MARK3	0.436	0.048
BAD	MARK3	0.436	0.1	mutually_exclusive (P31947)
BRAF	KIAA0930	0.436	0.11	mutually_exclusive (P27348)
SPIRE1	MARK3	0.436	0.136
KIAA0930	MARK3	0.436	0.082
PI4KB	BRAF	0.436	0.104
CDC25B	MARK3	0.436	0.082
TIAM1	MARK3	0.436	0.13
PI4KB	MARK1	0.436	0.148
CLASP1	SMTNL2	0.426
SMTNL2	BRAF	0.426		mutually_exclusive (P27348)
DENND4A	MARK3	0.424	0.044
SAMD4B	MARK1	0.416	0.078
SRGAP2	MARK1	0.413	0.16
FAM53B	MARK3	0.413
MARK1	BRAF	0.413	0.122
MARK1	DENND4A	0.4	0.072	mutually_exclusive (P27348)
ARHGEF38	YWHAH	0.397
SRGAP2	SAMD4B	0.396	0.034
YWHAZ	SASH1	0.393	0.507145833333
SASH1	YWHAE	0.393	0.344
PLEKHA7	IRS2	0.39	0.158
SRGAP2	MARK3	0.389	0.072
HOMEZ	PFKFB2	0.385	0.136	mutually_exclusive (P27348)
SYDE2	BAD	0.385
SRGAP1	BAD	0.385	0.08
PTPN3	BAD	0.385	0.128
SRGAP1	CDC25B	0.385	0.156
MARK1	PTPN3	0.385	0.122
PACS2	PFKFB2	0.385	0.064
HOMEZ	SPIRE1	0.385	0.074
SYDE2	MARK1	0.385
SRGAP1	MARK1	0.385	0.136
PACS2	SPIRE1	0.385	0.092
PLEKHA7	HOMEZ	0.385	0.066
SYDE2	CDC25B	0.385
PACS2	PLEKHA7	0.385	0.1
PACS2	HOMEZ	0.385	0.076
CDC25B	PTPN3	0.385	0.092
SPIRE1	YWHAE	0.37	0.368
PFKFB2	YWHAE	0.37	0.49695890411	mutually_exclusive (P27348)
SAMD4B	HDAC5	0.359	0.21
IRS2	HDAC5	0.353	0.102
SFN	MARK3	0.351	0.112	structurally_consistent (dimer)
SYDE2	FOXO3	0.35
MARK1	YWHAE	0.334	0.469033138402
HDAC4	PTPN3	0.324	0.134
SRGAP1	HDAC4	0.324	0.204
SYDE2	FOXO1	0.324
SYDE2	FOXO4	0.324
PTPN3	FOXO1	0.324	0.162
SRGAP1	FOXO1	0.324	0.212
HDAC4	SYDE2	0.324
FOXO3	FOXO4	0.324
SYDE2	FAM53B	0.319
PFKFB2	PTPN3	0.319	0.084
PACS2	FOXO3	0.319	0.146
HOMEZ	FOXO1	0.319	0.114	mutually_exclusive (P27348)
SRGAP1	IRS2	0.319	0.272
HOMEZ	TIAM1	0.319	0.136
SYDE2	PTPN3	0.319
SRGAP1	TIAM1	0.319	0.256
PTPN3	FAM53B	0.319
CRTC1	PTPN3	0.319	0.18
MAP3K3	HOMEZ	0.319	0.07
PACS2	TIAM1	0.319	0.16
SRGAP1	SYDE2	0.319
SRGAP1	HDAC5	0.319	0.082
PTPN3	HDAC5	0.319	0.154
SRGAP1	FOXO3	0.319	0.148
SRGAP1	FAM53B	0.319
SRGAP1	SPIRE1	0.319	0.156
SRGAP1	PFKFB2	0.319	0.076
SYDE2	PLEKHA7	0.319
MAP3K3	SYDE2	0.319
SRGAP1	PTPN3	0.319	0.186
SYDE2	CRTC1	0.319
SRGAP1	TFEB	0.319	0.142
SYDE2	HDAC5	0.319
SYDE2	IRS2	0.319
SRGAP1	PLEKHA7	0.319	0.154
HOMEZ	IRS2	0.319	0.116
HOMEZ	FAM53B	0.319
TIAM1	PTPN3	0.319	0.144
HOMEZ	FOXO3	0.319	0.126
MAP3K3	PACS2	0.319	0.096
SYDE2	PFKFB2	0.319
MAP3K3	PTPN3	0.319	0.138
SYDE2	HOMEZ	0.319
PACS2	TFEB	0.319	0.112
SYDE2	TFEB	0.319
SRGAP1	HOMEZ	0.319	0.072
TFEB	PTPN3	0.319	0.086
SRGAP1	CRTC1	0.319	0.144
SYDE2	SPIRE1	0.319
PACS2	CRTC1	0.319	0.13
PACS2	PTPN3	0.319	0.088
CRTC1	HOMEZ	0.319	0.158	mutually_exclusive (P27348)
PACS2	HDAC5	0.319	0.096
PACS2	SYDE2	0.319
PACS2	FOXO1	0.319	0.198
PACS2	FAM53B	0.319
PACS2	MAP3K2	0.319	0.072
PACS2	HDAC4	0.319	0.15
HOMEZ	MAP3K2	0.319	0.178	mutually_exclusive (P27348)
HOMEZ	TFEB	0.319	0.044
SYDE2	TIAM1	0.319
MAP3K3	SRGAP1	0.319	0.134
HOMEZ	PTPN3	0.319	0.094
HDAC4	HOMEZ	0.319	0.204	mutually_exclusive (P27348)
SRGAP1	MAP3K2	0.319	0.072
PTPN3	SPIRE1	0.319	0.13
FOXO3	PTPN3	0.319	0.2
MAP3K2	PTPN3	0.319	0.144
PACS2	SRGAP1	0.319	0.212
SYDE2	MAP3K2	0.319
FOXO3	FOXO1	0.317	0.168
SRGAP2	TFEB	0.301	0.154
SRGAP2	PLEKHA7	0.301	0.112
GPSM3	MARK3	0.3	0.044
SRGAP2	HDAC5	0.298	0.208
MAP3K3	MARK1	0.294	0.094
SRGAP1	DENND4A	0.29	0.086
SYDE2	KIAA0930	0.29
SRGAP1	KIAA0930	0.29	0.088
PTPN3	KIAA0930	0.29	0.148
SRGAP2	SYDE2	0.29
SYDE2	DENND4A	0.29
PACS2	MARK1	0.29	0.128
PACS2	CDC25B	0.29	0.082
HOMEZ	BAD	0.29	0.058	mutually_exclusive (P27348)
PACS2	BAD	0.29	0.144
HOMEZ	MARK1	0.29	0.148	mutually_exclusive (P27348)
DENND4A	PTPN3	0.29	0.102
HOMEZ	CDC25B	0.29	0.08	mutually_exclusive (P27348)
SRGAP2	DENND4A	0.283	0.034
CLASP1	PTPN3	0.283	0.19
PACS2	DENND4A	0.283	0.116
SYDE2	BRAF	0.283
SRGAP1	CLASP1	0.283	0.166
PACS2	PI4KB	0.283	0.134
MAP3K2	FOXO4	0.283
FOXO4	IRS2	0.283
HOMEZ	DENND4A	0.283	0.07	mutually_exclusive (P27348)
BRAF	PTPN3	0.283	0.104
SRGAP1	SASH1	0.283	0.136
PI4KB	PTPN3	0.283	0.14
SRGAP1	BRAF	0.283	0.15
SYDE2	CLASP1	0.283
HDAC4	FOXO4	0.283
SYDE2	SASH1	0.283
FOXO4	HDAC5	0.283		mutually_exclusive (P31947)
HOMEZ	CLASP1	0.283	0.126
SASH1	FOXO4	0.283
SYDE2	PI4KB	0.283
SASH1	PTPN3	0.283	0.09
SAMD4B	FOXO4	0.283
HOMEZ	BRAF	0.283	0.218	mutually_exclusive (P27348)
HOMEZ	KIAA0930	0.283	0.052	mutually_exclusive (P27348)
HOMEZ	SASH1	0.283	0.07	mutually_exclusive (P27348)
PACS2	KIAA0930	0.283	0.066
PACS2	BRAF	0.283	0.142
CRTC1	FOXO4	0.283
PI4KB	HOMEZ	0.283	0.186
FOXO4	FOXO1	0.283
PACS2	CLASP1	0.283	0.064
PACS2	SASH1	0.283	0.116
SRGAP1	PI4KB	0.283	0.178
FOXO3	DENND4A	0.282	0.1
CRTC1	YWHAE	0.28	0.355333333333
SRGAP2	CRTC1	0.278	0.13	mutually_exclusive (P27348)
DENND4A	HDAC5	0.278	0.086
SRGAP2	YWHAE	0.278	0.42
CLASP1	FOXO4	0.277
HOMEZ	YWHAE	0.277	0.459033138402	mutually_exclusive (P27348)
MAP3K3	DENND4A	0.275	0.156
MAP3K3	SRGAP2	0.275	0.172133333333
MAP3K3	CRTC1	0.271	0.084
CRTC1	MARK3	0.27	0.092
HDAC5	MARK3	0.27	0.146	mutually_exclusive (P31947)
FOXO1	MARK3	0.27	0.088
PACS2	SAMD4B	0.262	0.068
YWHAZ	SPIRE2	0.261
SAMD4B	FOXO3	0.254	0.132
TFEB	MARK3	0.254	0.112
SAMD4B	DENND4A	0.254	0.04
SRGAP2	SAMD4A	0.254	0.14
HDAC5	YWHAE	0.249	0.52880733195	mutually_exclusive (P31947)
SAMD4B	MARK3	0.249	0.062
PTOV1	FOXO1	0.246	0.142
SMTNL2	TIAM1	0.246
SMTNL2	PTPN3	0.246
PLEKHA7	SMTNL2	0.246
SMTNL2	KIAA0930	0.246
MARK1	SMTNL2	0.246		mutually_exclusive (P27348)
SYDE2	SMTNL2	0.246
SMTNL2	SAMD4A	0.246
PFKFB2	SMTNL2	0.246		mutually_exclusive (P27348)
SMTNL2	FOXO3	0.246
SMTNL2	FAM53B	0.246
MAP3K3	SMTNL2	0.246
HOMEZ	SMTNL2	0.246		mutually_exclusive (P27348)
PACS2	SMTNL2	0.246
MARK1	SFN	0.246	0.36
SRGAP1	SMTNL2	0.246
SMTNL2	SPIRE1	0.246
SMTNL2	TFEB	0.246
SPIRE2	SMTNL2	0.246
SMTNL2	CDC25B	0.246		mutually_exclusive (P27348)
SAMD4B	BRAF	0.245	0.092
PI4KB	MARK3	0.243	0.136
MAP3K3	BRAF	0.241	0.08
FOXO4	PTOV1	0.239		mutually_exclusive (P31947)
PLEKHA7	SFN	0.239	0.3584
SFN	SPIRE1	0.239	0.224564102564
FOXO4	BRAF	0.238
FOXO4	SAMD4A	0.238
FOXO4	PTPN3	0.238
PTPN3	MARK3	0.238	0.222
PFKFB2	FOXO4	0.238
SRGAP1	FOXO4	0.238
FOXO4	TFEB	0.238
SRGAP1	PTOV1	0.238	0.118
SRGAP1	SPIRE2	0.238
SYDE2	SAMD4B	0.238
PI4KB	FOXO4	0.238
SYDE2	SAMD4A	0.238
CDC25B	FOXO4	0.238
FOXO4	TIAM1	0.238
HOMEZ	FOXO4	0.238
PACS2	SAMD4A	0.238	0.076
SYDE2	MARK3	0.238
PLEKHA7	FOXO4	0.238
HOMEZ	SPIRE2	0.238
SMTNL2	BAD	0.238
SPIRE2	FOXO4	0.238
SMTNL2	FOXO1	0.238		mutually_exclusive (P27348)
SMTNL2	HDAC5	0.238		mutually_exclusive (P31947)
MAP3K2	SMTNL2	0.238		mutually_exclusive (P27348)
FOXO4	DENND4A	0.238
FOXO4	FAM53B	0.238
CRTC1	SMTNL2	0.238		mutually_exclusive (P27348)
FOXO4	SPIRE1	0.238
HOMEZ	SAMD4A	0.238	0.122
MAP3K3	FOXO4	0.238
PACS2	FOXO4	0.238
SRGAP1	SAMD4A	0.238	0.246
SAMD4A	PTPN3	0.238	0.124
FOXO4	KIAA0930	0.238		mutually_exclusive (P31947)
SRGAP1	MARK3	0.238	0.14
SPIRE2	PTPN3	0.238
SYDE2	SPIRE2	0.238
MARK1	FOXO4	0.238
SMTNL2	FOXO4	0.238		mutually_exclusive (P31947)
PACS2	SPIRE2	0.238
SAMD4B	SMTNL2	0.238
HDAC4	SMTNL2	0.238
SMTNL2	SASH1	0.238		mutually_exclusive (P27348)
SMTNL2	IRS2	0.238
PACS2	MARK3	0.238	0.102
FOXO4	BAD	0.238		mutually_exclusive (P31947)
MAP3K3	HDAC5	0.237	0.108
MAP3K3	FAM53B	0.237
HOMEZ	SFN	0.234	0.35725	mutually_exclusive (P27348)
SAMD4B	PTPN3	0.232	0.114
MAP3K3	SPIRE2	0.231
PLEKHA7	TIAM1	0.23	0.14
SRGAP2	FOXO4	0.224
FOXO4	MARK3	0.224		mutually_exclusive (P31947)
HOMEZ	MARK3	0.224	0.134
PLEKHA7	MARK3	0.221	0.05
CLASP1	BRAF	0.219	0.174
PTOV1	MARK3	0.218	0.098	mutually_exclusive (P31947)
HOMEZ	HDAC5	0.213	0.236
PACS2	IRS2	0.213	0.098
SAMD4B	SFN	0.208	0.09
FOXO3	MARK3	0.201	0.222
MAP3K3	MARK3	0.201	0.09
SRGAP2	PTPN3	0.191	0.132
SRGAP2	SFN	0.189	0.266
SFN	FOXO4	0.189		structurally_consistent (dimer)
SFN	DENND4A	0.189	0.203047619048	mutually_exclusive (P27348)
SAMD4B	PTOV1	0.189	0.052
FOXO1	YWHAE	0.18	0.476746666667	mutually_exclusive (P27348)
CDR2L	FOXO1	0.179	0.146
DENND4A	PTOV1	0.177	0.034
SAMD4B	CDR2L	0.176	0.09
CDR2L	TFEB	0.172	0.126
PLEKHA7	CDR2L	0.171	0.108
PACS2	SRGAP2	0.168	0.156133333333
SRGAP2	HOMEZ	0.168	0.18	mutually_exclusive (P27348)
CDR2L	SPIRE2	0.166
CLASP1	MARK3	0.165	0.084
FOXO4	YWHAE	0.156		mutually_exclusive (P31947)
PI4KB	SFN	0.155	0.116
PI4KB	PTOV1	0.155	0.128
CDR2L	SASH1	0.155	0.114
CDR2L	SAMD4A	0.155	0.146
SRGAP1	SAMD4B	0.153	0.136
SAMD4B	HOMEZ	0.153	0.084
CLASP1	SFN	0.151	0.173909090909
CLASP1	CDR2L	0.147	0.108
CDR2L	SPIRE1	0.147	0.152
CDR2L	BAD	0.147	0.13
PFKFB2	CDR2L	0.147	0.166
CDR2L	IRS2	0.146	0.134
TIAM1	YWHAE	0.146	0.445033138402
PI4KB	CDR2L	0.145	0.198
SPIRE2	YWHAE	0.145
CDR2L	KIAA0930	0.144	0.106
PLEKHA7	SAMD4B	0.144	0.072
MARK1	CDR2L	0.142	0.168
CDR2L	BRAF	0.14	0.116
CDR2L	DENND4A	0.138	0.064
HDAC4	CDR2L	0.133	0.13
CDR2L	CDC25B	0.133	0.098
CDR2L	TIAM1	0.133	0.148
CDR2L	MAP3K2	0.133	0.222
CDR2L	FAM53B	0.128
ANKRD55	SFN	0.128
CDR2L	HDAC5	0.125	0.206
HOMEZ	CDR2L	0.124	0.078
CDR2L	FOXO3	0.12	0.136
CRTC1	CDR2L	0.12	0.068
DENND4A	YWHAE	0.116	0.12	mutually_exclusive (P27348)
PLEKHG5	DMTN	0.113
SFN	SPIRE2	0.096
SAMD4A	PTOV1	0.096	0.066
SPIRE2	PTOV1	0.096
CLASP1	PTOV1	0.096	0.108
PLEKHG5	MARK3	0.095
CDR2L	SMTNL2	0.092
PI4KB	YWHAE	0.086	0.21
PLEKHG5	PTOV1	0.082
YWHAG	MAP2K5	0.082	0.216
DMTN	PTOV1	0.081	0.11
PACS2	CDR2L	0.08	0.092
DMTN	DENND4A	0.079	0.038
PLEKHG5	PTPN3	0.079
DMTN	SPIRE1	0.079	0.108
DMTN	HDAC5	0.079	0.076
PLEKHG5	TFEB	0.079
PACS2	PLEKHG5	0.079
DMTN	SMTNL2	0.079		mutually_exclusive (P27348)
DMTN	MARK3	0.079	0.078
MAP3K3	DMTN	0.079	0.11
MARK1	DMTN	0.079	0.064	mutually_exclusive (P27348)
PLEKHG5	BAD	0.079
DMTN	FOXO4	0.079
DMTN	TIAM1	0.079	0.272
PFKFB2	DMTN	0.079	0.064	mutually_exclusive (P27348)
DMTN	IRS2	0.079	0.134
PACS2	DMTN	0.079	0.092
DMTN	FAM53B	0.079
DMTN	MAP3K2	0.079	0.08	mutually_exclusive (P27348)
PLEKHG5	IRS2	0.079
PLEKHG5	HDAC5	0.079
PLEKHA7	DMTN	0.079	0.15
PLEKHG5	MAP3K2	0.079
DMTN	PTPN3	0.079	0.182
SYDE2	DMTN	0.079
DMTN	KIAA0930	0.079	0.064	mutually_exclusive (P27348)
PLEKHG5	SAMD4A	0.079
DMTN	TFEB	0.079	0.126
MAP3K3	PLEKHG5	0.079
DMTN	SPIRE2	0.079
DMTN	CDC25B	0.079	0.138	mutually_exclusive (P27348)
PLEKHG5	PLEKHA7	0.079
PLEKHG5	CRTC1	0.079
DMTN	BRAF	0.079	0.096	mutually_exclusive (P27348)
PLEKHG5	SASH1	0.079
DMTN	SASH1	0.079	0.152	mutually_exclusive (P27348)
CRTC1	DMTN	0.079	0.09	mutually_exclusive (P27348)
SRGAP2	DMTN	0.079	0.13	mutually_exclusive (P27348)
PLEKHG5	FOXO4	0.079
PLEKHG5	SAMD4B	0.079
PLEKHG5	CLASP1	0.079
PLEKHG5	CDC25B	0.079
PLEKHG5	SPIRE1	0.079
PLEKHG5	HOMEZ	0.079
PLEKHG5	PI4KB	0.079
HDAC4	DMTN	0.079	0.108
PI4KB	DMTN	0.079	0.104
SRGAP1	DMTN	0.079	0.166
DMTN	SAMD4A	0.079	0.074
PLEKHG5	MARK1	0.079
PLEKHG5	FOXO1	0.079
PLEKHG5	FOXO3	0.079
PLEKHG5	FAM53B	0.079
PLEKHG5	DENND4A	0.079
PLEKHG5	HDAC4	0.079
PLEKHG5	PFKFB2	0.079
PLEKHG5	KIAA0930	0.079
DMTN	FOXO1	0.079	0.134	mutually_exclusive (P27348)
SRGAP1	PLEKHG5	0.079
PLEKHG5	TIAM1	0.079
SAMD4B	DMTN	0.079	0.058
PLEKHG5	SPIRE2	0.079
CLASP1	DMTN	0.079	0.054
PLEKHG5	SMTNL2	0.079
DMTN	FOXO3	0.079	0.118
HOMEZ	DMTN	0.079	0.092	mutually_exclusive (P27348)
PLEKHG5	SYDE2	0.079
DMTN	BAD	0.079	0.08	mutually_exclusive (P27348)
PLEKHG5	BRAF	0.079
SRGAP2	PLEKHG5	0.079
CDR2L	DMTN	0.076	0.154
PLEKHA7	YWHAE	0.075	0.188
CDR2L	FOXO4	0.071
PLEKHG5	CDR2L	0.071
SYDE2	CDR2L	0.071
SRGAP1	CDR2L	0.071	0.19
CDR2L	PTPN3	0.071	0.156
ARHGEF38	SFN	0.071
SMTNL2	PTOV1	0.069		mutually_exclusive (P31947)
FOXO3	YWHAE	0.059	0.426900900901
SFN	PTOV1	0.057	0.256	structurally_consistent (dimer)
MAP3K3	CDR2L	0.057	0.124
SRGAP2	CDR2L	0.057	0.126
CLASP1	YWHAQ	0.055	0.286
MARK3	YWHAE	0.051	0.27
CLASP1	YWHAE	0.05	0.256
MAP2K5	DENND4A	0.043	0.08
SAMD4B	CLASP1	0.038	0.058
CDR2L	MARK3	0.037	0.134
GPSM3	PTOV1	0.035
CDR2L	PTOV1	0.027	0.16
MAP2K5	YWHAH	0.025	0.224
SFN	MAP2K5	0.017	0.15
MAP2K5	YWHAB	0.016	0.198626373626	structurally_consistent (dimer)
YWHAQ	MAP2K5	0.014	0.238
YWHAZ	MAP2K5	0.009	0.353111111111
CERT1	YWHAB	0.005	0.156726027397
CERT1	YWHAE	0.004	0.106
YWHAZ	CERT1	0.004	0.138769230769
CERT1	YWHAQ	0.004	0.172

Related Complexes

Genename	Complexes
PLEKHA7	huMAP3_01010.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CDR2L	huMAP3_01787.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SMTNL2	huMAP3_02971.1 huMAP3_04537.1 huMAP3_07596.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14527.1
PI4KB	huMAP3_01010.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_12954.1
TIAM1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
ARHGEF38	huMAP3_01699.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_10808.1 huMAP3_13503.1
MAP3K3	huMAP3_00011.1 huMAP3_03708.1 huMAP3_08523.1 huMAP3_10808.1 huMAP3_10861.1 huMAP3_12897.1
YWHAQ	huMAP3_01787.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
GPSM3	huMAP3_00362.1 huMAP3_01653.1 huMAP3_06782.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CERT1	huMAP3_01298.1 huMAP3_09812.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_11652.1 huMAP3_14496.1
DENND4A	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14817.1
PACS2	huMAP3_00173.1 huMAP3_04537.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10190.1 huMAP3_10808.1 huMAP3_12897.1
SAMD4A	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14098.1
SRGAP1	huMAP3_00235.1 huMAP3_04537.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10496.1 huMAP3_10808.1 huMAP3_11883.1 huMAP3_12561.1 huMAP3_12897.1 huMAP3_13128.1 huMAP3_13156.1 huMAP3_13524.1
TFEB	huMAP3_04102.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_08832.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13402.1 huMAP3_13503.1
ANKRD55	huMAP3_01787.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CDC25B	huMAP3_03088.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07002.1 huMAP3_07596.1 huMAP3_07691.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10829.1 huMAP3_12772.1 huMAP3_12897.1
IRS2	huMAP3_04537.1 huMAP3_07081.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_08092.1 huMAP3_09358.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_11629.1 huMAP3_12185.1 huMAP3_12897.1 huMAP3_14118.1
SPATA13	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
PLEKHG5	huMAP3_00362.1 huMAP3_01841.1 huMAP3_05451.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09174.1 huMAP3_09810.1 huMAP3_10180.1 huMAP3_10808.1 huMAP3_12897.1
SPIRE2	huMAP3_02462.1 huMAP3_04537.1 huMAP3_06108.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13929.1 huMAP3_15248.1
SASH1	huMAP3_03955.1 huMAP3_04051.1 huMAP3_04537.1 huMAP3_07306.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
MARK1	huMAP3_01298.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_09812.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_12897.1
SAMD4B	huMAP3_01010.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_14098.1
FOXO3	huMAP3_03955.1 huMAP3_04051.1 huMAP3_04537.1 huMAP3_06135.1 huMAP3_07306.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
DMTN	huMAP3_01787.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_12991.1
HOMEZ	huMAP3_01010.1 huMAP3_04993.1 huMAP3_08920.1 huMAP3_10808.1 huMAP3_12897.1
SYDE2	huMAP3_00566.1 huMAP3_04537.1 huMAP3_06797.1 huMAP3_06971.1 huMAP3_08480.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10974.1 huMAP3_12897.1 huMAP3_14687.1
MARK3	huMAP3_06971.1 huMAP3_07596.1 huMAP3_09266.1 huMAP3_09812.1 huMAP3_10544.1 huMAP3_10561.1 huMAP3_10808.1 huMAP3_12897.1
LNP1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13672.1
PTOV1	huMAP3_04537.1 huMAP3_05308.1 huMAP3_07324.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_08154.1 huMAP3_09641.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1
MAP2K5	huMAP3_02733.1 huMAP3_03261.1 huMAP3_03708.1 huMAP3_10808.1 huMAP3_10861.1
BRAF	huMAP3_04537.1 huMAP3_04917.1 huMAP3_07588.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11448.1 huMAP3_12897.1
PTPN3	huMAP3_04537.1 huMAP3_06025.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11201.1 huMAP3_12897.1
KIAA0930	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11622.1 huMAP3_12897.1
YWHAB	huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
PFKFB2	huMAP3_01672.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CLASP1	huMAP3_01699.1 huMAP3_07247.1 huMAP3_08158.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_10808.1 huMAP3_12301.1
SFN	huMAP3_01787.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SPIRE1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13929.1 huMAP3_15248.1
FAM53B	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
BAD	huMAP3_04537.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11267.1 huMAP3_12897.1 huMAP3_13356.1
YWHAE	huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13503.1
YWHAH	huMAP3_04051.1 huMAP3_04537.1 huMAP3_06971.1 huMAP3_07306.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
MAP3K2	huMAP3_02733.1 huMAP3_03708.1 huMAP3_08523.1 huMAP3_10808.1 huMAP3_10861.1 huMAP3_12897.1
YWHAZ	huMAP3_00362.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
HDAC5	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
CRTC1	huMAP3_01010.1 huMAP3_04051.1 huMAP3_06971.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1 huMAP3_13650.1
FOXO1	huMAP3_04537.1 huMAP3_06971.1 huMAP3_07424.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
HDAC4	huMAP3_00531.1 huMAP3_04537.1 huMAP3_06269.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09641.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10898.1 huMAP3_12897.1 huMAP3_14118.1
FOXO4	huMAP3_04051.1 huMAP3_04537.1 huMAP3_07424.1 huMAP3_08480.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
YWHAG	huMAP3_01010.1 huMAP3_03955.1 huMAP3_06135.1 huMAP3_06971.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1
SRGAP2	huMAP3_00235.1 huMAP3_02549.1 huMAP3_04537.1 huMAP3_05977.1 huMAP3_07838.1 huMAP3_08222.1 huMAP3_09542.1 huMAP3_09810.1 huMAP3_10496.1 huMAP3_10808.1 huMAP3_11531.1 huMAP3_12897.1
A0A1X9RU27	huMAP3_01787.1 huMAP3_03955.1 huMAP3_07424.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_12897.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10808.1

Complex Portal: CPX-10978