hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10815.1

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
ESCO2	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment factor-like protein 2) (EFO2) (EFO2p) (hEFO2) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2)	5	UniProt NCBI
NONO	Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)	5	UniProt NCBI
ORC6	Origin recognition complex subunit 6	5	UniProt NCBI
PSPC1	Paraspeckle component 1 (Paraspeckle protein 1)	5	UniProt NCBI
SFPQ	Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)	5	UniProt NCBI

Showing 1 to 5 of 5 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7285	7.68662167609e-05	0.5	PSPC1 NONO	HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex
HP:0006443	0.00454201288615	0.5	ORC6 ESCO2	Patellar aplasia
HP:0006498	0.0108451581837	0.5	ORC6 ESCO2	Aplasia/Hypoplasia of the patella
HP:0012880	0.0135443934278	0.5	ORC6 ESCO2	Abnormal labia minora morphology
CORUM:330	0.0249718442456	0.25	NONO	PSF-p54(nrb) complex
CORUM:1760	0.0249718442456	0.25	NONO	TOP1-PSF-P54 complex
HPA:0570783	0.0258977031751	0.75	PSPC1 ORC6 NONO	testis; preleptotene spermatocytes[High]
KEGG:04110	0.0280208578488	0.5	ORC6 ESCO2	Cell cycle
HP:0004278	0.028689358225	0.5	NONO ESCO2	Synostosis involving bones of the hand
WP:WP3594	0.03162086928	0.5	PSPC1 NONO	Circadian rhythm genes

Showing 1 to 10 of 14 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
NONO	SFPQ	1.0	0.992	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM
PSPC1	NONO	1.0	0.62	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM
PSPC1	SFPQ	0.999	0.674	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM
ORC6	NONO	0.972	0.22	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
PSPC1	ESCO2	0.96	0.108	hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM gupta_WMM WMM_only
ORC6	SFPQ	0.959	0.12	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
ORC6	PSPC1	0.957	0.092	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
NONO	ESCO2	0.856	0.102	hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only
SFPQ	ESCO2	0.843	0.074	hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only
ORC6	ESCO2	0.102	0.164	bioplex3_WMM WMM_only

Showing 1 to 10 of 10 entries

Related Complexes

Genename	Complexes
PSPC1	huMAP3_02652.1 huMAP3_08040.1 huMAP3_09024.1 huMAP3_09275.1 huMAP3_09312.1 huMAP3_09423.1 huMAP3_10666.1 huMAP3_10815.1 huMAP3_10999.1 huMAP3_13443.1 huMAP3_14270.1 huMAP3_14405.1 huMAP3_14559.1
ORC6	huMAP3_00083.1 huMAP3_00827.1 huMAP3_02652.1 huMAP3_04602.1 huMAP3_07377.1 huMAP3_07727.1 huMAP3_09024.1 huMAP3_10372.1 huMAP3_10666.1 huMAP3_10815.1 huMAP3_10999.1 huMAP3_11726.1 huMAP3_12998.1 huMAP3_13443.1 huMAP3_14270.1 huMAP3_14405.1
NONO	huMAP3_02652.1 huMAP3_02877.1 huMAP3_03457.1 huMAP3_08040.1 huMAP3_09024.1 huMAP3_09275.1 huMAP3_09312.1 huMAP3_10666.1 huMAP3_10815.1 huMAP3_10999.1 huMAP3_13443.1 huMAP3_14270.1 huMAP3_14405.1 huMAP3_14559.1
ESCO2	huMAP3_03658.1 huMAP3_10815.1 huMAP3_11159.1 huMAP3_13443.1 huMAP3_14270.1 huMAP3_14405.1 huMAP3_14559.1
SFPQ	huMAP3_02877.1 huMAP3_03457.1 huMAP3_09275.1 huMAP3_09312.1 huMAP3_10666.1 huMAP3_10815.1 huMAP3_10999.1 huMAP3_13443.1 huMAP3_14270.1 huMAP3_14405.1 huMAP3_14559.1