hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10824.1

Complex Portal: CPX-18902

Confidence: Medium High

Show entries

Search:

Genename	Protein Name	Uniprot Annotation Score	Links
DEFB104A	Beta-defensin 104 (Beta-defensin 4) (BD-4) (DEFB-4) (hBD-4) (Defensin, beta 104)	5	UniProt NCBI
GNA13	Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)	5	UniProt NCBI
GNAI1	Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)	5	UniProt NCBI
GNAI2	Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein)	5	UniProt NCBI
GNAI3	Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)	5	UniProt NCBI
GNAO1	Guanine nucleotide-binding protein G(o) subunit alpha	5	UniProt NCBI
GNAQ	Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)	5	UniProt NCBI
GNAT2	Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain)	5	UniProt NCBI
GNAT3	Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain)	5	UniProt NCBI
GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)	5	UniProt NCBI

Showing 1 to 10 of 26 entries

Enrichments

Show entries

Search:

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005834	4.0500864746e-42	0.75	GNG12 GNAI2 GNG10 GNAQ GNAT3 GNB1 GNG7 GNAT2 GNAI3 GNG4 GNAI1 GNAO1 GNB4 GNB2 GNA13 GNGT1 GNG11 GNG5	heterotrimeric G-protein complex
GO:1905360	4.23954708725e-40	0.75	GNG12 GNAI2 GNG10 GNAQ GNAT3 GNB1 GNG7 GNAT2 GNAI3 GNG4 GNAI1 GNAO1 GNB4 GNB2 GNA13 GNGT1 GNG11 GNG5	GTPase complex
REAC:R-HSA-392518	1.5478145647e-37	0.666666666667	GNG12 GNG10 GNAQ GNAT3 GNAI2 GNG7 GNAI3 GNG4 GNAI1 GNB1 GNB4 GNB2 GNA13 GNGT1 GNG11 GNG5	Signal amplification
GO:0031234	4.28109293228e-35	0.75	GNG12 GNAI2 GNG10 GNAQ GNAT3 GNB1 GNG7 GNAT2 GNAI3 GNG4 GNAI1 GNAO1 GNB4 GNB2 GNA13 GNGT1 GNG11 GNG5	extrinsic component of cytoplasmic side of plasma membrane
REAC:R-HSA-392170	9.80471469217e-35	0.583333333333	GNG12 GNG10 GNAT3 GNAI2 GNG7 GNAI3 GNG4 GNAI1 GNB1 GNB4 GNB2 GNGT1 GNG11 GNG5	ADP signalling through P2Y purinoceptor 12
GO:0019897	2.68435364531e-31	0.75	GNG12 GNAI2 GNG10 GNAQ GNAT3 GNB1 GNG7 GNAT2 GNAI3 GNG4 GNAI1 GNAO1 GNB4 GNB2 GNA13 GNGT1 GNG11 GNG5	extrinsic component of plasma membrane
REAC:R-HSA-991365	2.05409787468e-30	0.583333333333	GNG12 GNG10 GNAT3 GNAI2 GNG7 GNAI3 GNG4 GNAI1 GNB1 GNB4 GNB2 GNGT1 GNG11 GNG5	Activation of GABAB receptors
REAC:R-HSA-977444	2.05409787468e-30	0.583333333333	GNG12 GNG10 GNAT3 GNAI2 GNG7 GNAI3 GNG4 GNAI1 GNB1 GNB4 GNB2 GNGT1 GNG11 GNG5	GABA B receptor activation
REAC:R-HSA-418594	4.59614294804e-30	0.791666666667	GNG12 GNAI2 GNG10 GNAT3 GNB1 GNG7 GNAT2 RGS14 GNG4 GNAQ GNB4 PPY RGS12 GNAI1 GNAI3 GNB2 GNGT1 GNG11 GNG5	G alpha (i) signalling events
REAC:R-HSA-418597	5.81249693609e-30	0.583333333333	GNG12 GNG10 GNAT3 GNAI2 GNG7 GNAI3 GNG4 GNAI1 GNB1 GNB4 GNB2 GNGT1 GNG11 GNG5	G alpha (z) signalling events

Showing 1 to 10 of 255 entries

Edges

Show entries

Search:

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
GNAI3	RIC8A	1.0	0.06
GNB2	GNB1	0.999	0.726
GNAI1	GNAI3	0.999	0.57	structurally_consistent (dimer)
GNAI3	GNAI2	0.999	0.286
GNAO1	RIC8A	0.999	0.068
GNG7	GNB1	0.999	0.150619047619
GNAO1	GNAI2	0.999	0.082
GNG5	GNB2	0.999	0.138
GNAI3	GNAO1	0.999	0.106
GNG5	GNB1	0.999	0.213	structurally_consistent (P16520) structurally_consistent (dimer)

Showing 1 to 10 of 255 entries

Related Complexes

Genename	Complexes
DEFB104A	huMAP3_03833.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11170.1 huMAP3_11377.1 huMAP3_11473.1 huMAP3_12896.1 huMAP3_13475.1 huMAP3_14171.1 huMAP3_15129.1
RGS12	huMAP3_01199.1 huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07243.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_15303.1
GNAT3	huMAP3_00585.1 huMAP3_02649.1 huMAP3_03009.1 huMAP3_07239.1 huMAP3_08287.1 huMAP3_08960.1 huMAP3_09788.1 huMAP3_10627.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_13880.1 huMAP3_14724.1
GNAI1	huMAP3_00466.1 huMAP3_05502.1 huMAP3_05674.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1
GNB2	huMAP3_03833.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_15129.1
GNG7	huMAP3_03550.1 huMAP3_05901.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNG12	huMAP3_03550.1 huMAP3_05674.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1
GNB4	huMAP3_03550.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
RGS14	huMAP3_00466.1 huMAP3_01486.1 huMAP3_05502.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12381.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAT2	huMAP3_02643.1 huMAP3_08140.1 huMAP3_08591.1 huMAP3_08840.1 huMAP3_09214.1 huMAP3_09609.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNG11	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12381.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNB3	huMAP3_07745.1 huMAP3_08586.1 huMAP3_09174.1 huMAP3_09788.1 huMAP3_10180.1 huMAP3_10236.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12374.1 huMAP3_12474.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAI3	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAO1	huMAP3_02643.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNGT1	huMAP3_07745.1 huMAP3_08586.1 huMAP3_09174.1 huMAP3_09185.1 huMAP3_10180.1 huMAP3_10236.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12474.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNAQ	huMAP3_05502.1 huMAP3_08591.1 huMAP3_08718.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12658.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNB1	huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
OTUD3	huMAP3_00585.1 huMAP3_02649.1 huMAP3_03009.1 huMAP3_04266.1 huMAP3_08287.1 huMAP3_09788.1 huMAP3_10627.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1 huMAP3_13880.1 huMAP3_14724.1
GNG10	huMAP3_02905.1 huMAP3_05901.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNG5	huMAP3_02905.1 huMAP3_05901.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
SMPDL3B	huMAP3_01486.1 huMAP3_03550.1 huMAP3_07033.1 huMAP3_07209.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_12658.1 huMAP3_14897.1
GNAI2	huMAP3_05473.1 huMAP3_05901.1 huMAP3_08591.1 huMAP3_08713.1 huMAP3_09165.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1
GNG4	huMAP3_03550.1 huMAP3_07033.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
PPY	huMAP3_02905.1 huMAP3_03302.1 huMAP3_05901.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11125.1 huMAP3_11173.1
RIC8A	huMAP3_05901.1 huMAP3_08591.1 huMAP3_09788.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1
GNA13	huMAP3_02649.1 huMAP3_02905.1 huMAP3_03009.1 huMAP3_05901.1 huMAP3_09480.1 huMAP3_10824.1 huMAP3_11173.1 huMAP3_12729.1 huMAP3_13105.1 huMAP3_13380.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10824.1

Complex Portal: CPX-18902