hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10832.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AZI2 | 5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (Nap1) (TILP) | 5 | UniProt NCBI |
| CHRDL1 | Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) | 5 | UniProt NCBI |
| CALCOCO2 | Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52) | 5 | UniProt NCBI |
| TBK1 | Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5212 | 0.000143457417375 | 0.5 | AZI2 TBK1 | Kinase maturation complex 2 |
| WP:WP3865 | 0.00363720277712 | 0.5 | AZI2 TBK1 | Novel intracellular components of RIG I like receptor pathway |
| KEGG:04622 | 0.00518715200321 | 0.5 | AZI2 TBK1 | RIG-I-like receptor signaling pathway |
| KEGG:04137 | 0.0118173906169 | 0.5 | CALCOCO2 TBK1 | Mitophagy - animal |
| KEGG:05164 | 0.0254912281659 | 0.5 | CALCOCO2 TBK1 | Influenza A |
| KEGG:04140 | 0.0298999303213 | 0.5 | CALCOCO2 TBK1 | Autophagy - animal |
| CORUM:7405 | 0.049938562206 | 0.25 | TBK1 | TMEM173-TBK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| AZI2 | CALCOCO2 | 0.996 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| AZI2 | TBK1 | 0.99 | 0.12 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| TBK1 | CALCOCO2 | 0.984 | 0.104 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CHRDL1 | CALCOCO2 | 0.982 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes