hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10850.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RABEP2 | Rab GTPase-binding effector protein 2 (Rabaptin-5beta) | 5 | UniProt NCBI |
| RABEP1 | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | 5 | UniProt NCBI |
| CEP192 | Centrosomal protein of 192 kDa (Cep192) (Cep192/SPD-2) | 5 | UniProt NCBI |
| C1orf122 | Uncharacterized protein C1orf122 (Protein ALAESM) | 2 | UniProt NCBI |
| RABGEF1 | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | 5 | UniProt NCBI |
| TAX1BP1 | Tax1-binding protein 1 (TRAF6-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:50 | 5.12534978153e-05 | 0.333333333333 | RABEP1 RABGEF1 | RAB5-RABAPTIN5-RABEX5 complex |
| WP:WP4950 | 0.00326040131097 | 0.333333333333 | RABEP2 RABGEF1 | 16p11 2 distal deletion syndrome |
| REAC:R-HSA-8854214 | 0.019003715544 | 0.333333333333 | RABEP1 RABGEF1 | TBC/RABGAPs |
| KEGG:04137 | 0.0339543001219 | 0.333333333333 | TAX1BP1 RABGEF1 | Mitophagy - animal |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RABEP2 | RABGEF1 | 1.0 | 0.192 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM |
| RABGEF1 | RABEP1 | 0.998 | 0.314 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM |
| C1orf122 | RABEP2 | 0.985 | 0.048 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| RABEP2 | RABEP1 | 0.982 | 0.074 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
| RABGEF1 | TAX1BP1 | 0.974 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CEP192 | RABEP2 | 0.973 | 0.076 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| C1orf122 | RABGEF1 | 0.476 | 0.084 | bioplex3_WMM WMM_only |
| CEP192 | RABGEF1 | 0.302 | 0.108 | bioplex3_WMM youn_WMM WMM_only |
| CEP192 | C1orf122 | 0.257 | 0.15 | bioplex3_WMM gupta_WMM WMM_only |
| TAX1BP1 | RABEP1 | 0.213 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| RABEP2 | TAX1BP1 | 0.127 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
| C1orf122 | RABEP1 | 0.027 | 0.058 | bioplex3_WMM gupta_WMM WMM_only |
| CEP192 | RABEP1 | 0.01 | 0.138 | youn_WMM gupta_WMM WMM_only |
Related Complexes