hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10854.1
Complex Portal: CPX-15672
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAGEC2 | Melanoma-associated antigen C2 (Cancer/testis antigen 10) (CT10) (Hepatocellular carcinoma-associated antigen 587) (MAGE-C2 antigen) (MAGE-E1 antigen) | 5 | UniProt NCBI |
| MAGEB4 | Melanoma-associated antigen B4 (MAGE-B4 antigen) | 5 | UniProt NCBI |
| MAGEB18 | Melanoma-associated antigen B18 (MAGE-B18 antigen) | 5 | UniProt NCBI |
| MAGEC3 | Melanoma-associated antigen C3 (Cancer/testis antigen 7.2) (CT7.2) (Hepatocellular carcinoma-associated antigen 2) (MAGE-C3 antigen) | 5 | UniProt NCBI |
| MAGEB10 | Melanoma-associated antigen B10 (MAGE-B10 antigen) | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000122 | 0.00654800781086 | 1.0 | MAGEB10 MAGEB18 MAGEC2 MAGEC3 MAGEB4 | negative regulation of transcription by RNA polymerase II |
| TF:M01709_1 | 0.0268158668335 | 1.0 | MAGEB10 MAGEB18 MAGEC2 MAGEC3 MAGEB4 | Factor: MAFA; motif: TCAGCAN; match class: 1 |
| GO:0045892 | 0.0359189932811 | 1.0 | MAGEB10 MAGEB18 MAGEC2 MAGEC3 MAGEB4 | negative regulation of DNA-templated transcription |
| GO:1902679 | 0.0380488436301 | 1.0 | MAGEB10 MAGEB18 MAGEC2 MAGEC3 MAGEB4 | negative regulation of RNA biosynthetic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAGEC3 | MAGEC2 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAGEB18 | MAGEB10 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAGEC2 | MAGEB10 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MAGEB10 | MAGEB4 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MAGEC2 | MAGEB4 | 0.977 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MAGEB18 | MAGEB4 | 0.214 | bioplex3_WMM WMM_only | ||
| MAGEC2 | MAGEB18 | 0.214 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MAGEC2 | huMAP3_01336.1 huMAP3_10854.1 |
| MAGEB4 | huMAP3_08786.1 huMAP3_09353.1 huMAP3_09852.1 huMAP3_10854.1 huMAP3_13369.1 huMAP3_14804.1 |
| MAGEB18 | huMAP3_04231.1 huMAP3_09353.1 huMAP3_10854.1 huMAP3_13369.1 |
| MAGEC3 | huMAP3_01336.1 huMAP3_10854.1 |
| MAGEB10 | huMAP3_04231.1 huMAP3_09353.1 huMAP3_10854.1 huMAP3_13369.1 |