hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10901.1
Complex Portal: CPX-24142
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPP1R8 | Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8) [Includes: Activator of RNA decay (EC 3.1.4.-) (ARD-1)] | 5 | UniProt NCBI |
| CCDC85B | Coiled-coil domain-containing protein 85B (Hepatitis delta antigen-interacting protein A) (Delta-interacting protein A) | 5 | UniProt NCBI |
| RASSF7 | Ras association domain-containing protein 7 (HRAS1-related cluster protein 1) | 5 | UniProt NCBI |
| PPP1R13B | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) | 5 | UniProt NCBI |
| PPP1R11 | E3 ubiquitin-protein ligase PPP1R11 (EC 2.3.2.27) (Hemochromatosis candidate gene V protein) (HCG V) (Protein phosphatase 1 regulatory subunit 11) (Protein phosphatase inhibitor 3) | 5 | UniProt NCBI |
| CNST | Consortin | 5 | UniProt NCBI |
| ZFYVE16 | Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) | 5 | UniProt NCBI |
| PPP1R18 | Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18) | 5 | UniProt NCBI |
| CCDC85C | Coiled-coil domain-containing protein 85C | 3 | UniProt NCBI |
| RASIP1 | Ras-interacting protein 1 (Rain) | 5 | UniProt NCBI |
| LMTK2 | Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2) | 5 | UniProt NCBI |
| KIF18A | Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4861 | 0.000479868106513 | 0.25 | PPP1R8 PPP1R13B PPP1R11 | Endoplasmic reticulum stress response in coronavirus infection |
| GO:0004864 | 0.0278917334495 | 0.25 | PPP1R8 LMTK2 PPP1R11 | protein phosphatase inhibitor activity |
| GO:0019212 | 0.0481447187643 | 0.25 | PPP1R8 LMTK2 PPP1R11 | phosphatase inhibitor activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| RASSF7 | PPP1R13B | 0.999 | 0.09 |
mutually_exclusive (P62140)
|
| PPP1R13B | CCDC85C | 0.995 | 0.138 | |
| RASIP1 | PPP1R18 | 0.992 | 0.064 | |
| CCDC85B | PPP1R13B | 0.992 | 0.124 | |
| PPP1R13B | CNST | 0.98 | 0.07 |
mutually_exclusive (P62136)
|
| CCDC85B | CCDC85C | 0.972 | 0.108 | |
| RASSF7 | PPP1R18 | 0.972 | 0.042 |
mutually_exclusive (P62140)
|
| PPP1R11 | PPP1R18 | 0.969 | 0.056 |
mutually_exclusive (P62136)
|
| CNST | PPP1R18 | 0.968 | 0.086 |
mutually_exclusive (P62136)
|
| PPP1R8 | LMTK2 | 0.967 | 0.094 | |
| PPP1R11 | CNST | 0.964 | 0.19 | |
| LMTK2 | PPP1R18 | 0.962 | 0.058 | |
| CCDC85C | ZFYVE16 | 0.962 | 0.068 |
mutually_exclusive (P62136)
|
| ZFYVE16 | PPP1R18 | 0.962 | 0.028 |
mutually_exclusive (P62136)
|
| CNST | ZFYVE16 | 0.962 | 0.044 |
mutually_exclusive (P62136)
|
| RASSF7 | PPP1R11 | 0.962 | 0.052 |
mutually_exclusive (P62140)
|
| RASSF7 | CNST | 0.961 | 0.102 | |
| PPP1R11 | ZFYVE16 | 0.959 | 0.018 |
mutually_exclusive (P62136)
|
| ZFYVE16 | KIF18A | 0.959 | 0.07 |
mutually_exclusive (P62136)
|
| LMTK2 | KIF18A | 0.959 | 0.114 | |
| PPP1R11 | LMTK2 | 0.959 | 0.056 | |
| CNST | LMTK2 | 0.959 | 0.106 | |
| ZFYVE16 | LMTK2 | 0.956 | 0.09 | |
| PPP1R8 | ZFYVE16 | 0.954 | 0.044 |
mutually_exclusive (P62136)
|
| CCDC85C | PPP1R11 | 0.953 | 0.152 | |
| CCDC85C | CNST | 0.951 | 0.132 | |
| CCDC85C | LMTK2 | 0.941 | 0.148 | |
| RASSF7 | LMTK2 | 0.936 | 0.12 | |
| CCDC85C | KIF18A | 0.928 | 0.148 | |
| PPP1R11 | KIF18A | 0.927 | 0.106 |
mutually_exclusive (P62136)
|
| PPP1R8 | PPP1R18 | 0.924 | 0.026 |
mutually_exclusive (P62136)
|
| CCDC85C | PPP1R18 | 0.923 | 0.04 | |
| RASSF7 | KIF18A | 0.922 | 0.09 | |
| PPP1R8 | PPP1R11 | 0.921 | 0.03 |
mutually_exclusive (P62136)
|
| PPP1R13B | LMTK2 | 0.921 | 0.084 | |
| KIF18A | PPP1R18 | 0.92 | 0.04 |
mutually_exclusive (P62136)
|
| CNST | KIF18A | 0.92 | 0.07 |
mutually_exclusive (P62136)
|
| PPP1R13B | PPP1R11 | 0.915 | 0.05 | |
| PPP1R8 | CNST | 0.914 | 0.092 |
mutually_exclusive (P62136)
|
| PPP1R13B | PPP1R8 | 0.908 | 0.072 | |
| PPP1R13B | KIF18A | 0.897 | 0.118 |
mutually_exclusive (P62136)
|
| PPP1R13B | PPP1R18 | 0.871 | 0.032 | |
| RASSF7 | PPP1R8 | 0.867 | 0.046 |
mutually_exclusive (P62140)
|
| RASSF7 | ZFYVE16 | 0.846 | 0.108 | |
| RASSF7 | CCDC85C | 0.837 | 0.182 |
mutually_exclusive (P62140)
|
| PPP1R8 | KIF18A | 0.834 | 0.1 |
mutually_exclusive (P62136)
|
| PPP1R13B | ZFYVE16 | 0.774 | 0.244 |
mutually_exclusive (P62136)
|
| CCDC85B | KIF18A | 0.74 | 0.138 | |
| CCDC85B | PPP1R8 | 0.723 | 0.08 | |
| CCDC85B | RASSF7 | 0.701 | 0.088 | |
| CCDC85B | PPP1R11 | 0.671 | 0.114 | |
| CCDC85C | PPP1R8 | 0.671 | 0.086 | |
| CCDC85B | ZFYVE16 | 0.6 | 0.076 | |
| CCDC85B | CNST | 0.557 | 0.114 | |
| CCDC85B | PPP1R18 | 0.536 | 0.11 | |
| CCDC85B | LMTK2 | 0.188 | 0.194 |
Related Complexes