hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10910.1

Complex Portal: CPX-21932

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
POMC	Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin]	5	UniProt NCBI
RBL2	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)	5	UniProt NCBI
E2F5	Transcription factor E2F5 (E2F-5)	5	UniProt NCBI
RBL1	Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)	5	UniProt NCBI
TFDP2	Transcription factor Dp-2 (E2F dimerization partner 2)	5	UniProt NCBI
E2F1	Transcription factor E2F1 (E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1) (Retinoblastoma-binding protein 3) (RBBP-3) (pRB-binding protein E2F-1)	5	UniProt NCBI
E2F4	Transcription factor E2F4 (E2F-4)	5	UniProt NCBI
LIN52	Protein lin-52 homolog	3	UniProt NCBI
LIN37	Protein lin-37 homolog (Antolefinin)	5	UniProt NCBI
LIN54	Protein lin-54 homolog (CXC domain-containing protein 1)	5	UniProt NCBI
E2F2	Transcription factor E2F2 (E2F-2)	5	UniProt NCBI
TESMIN	Tesmin (Metallothionein-like 5, testis-specific) (Testis-specific metallothionein-like protein)	4	UniProt NCBI
MYBL2	Myb-related protein B (B-Myb) (Myb-like protein 2)	5	UniProt NCBI
MYBL1	Myb-related protein A (A-Myb) (Myb-like protein 1)	5	UniProt NCBI
MCIDAS	Multicilin (Multiciliate differentiation and DNA synthesis-associated cell cycle protein) (McIdas protein) (Protein Idas)	5	UniProt NCBI
LIN9	Protein lin-9 homolog (HuLin-9) (hLin-9) (Beta subunit-associated regulator of apoptosis) (TUDOR gene similar protein) (Type I interferon receptor beta chain-associated protein) (pRB-associated protein)	5	UniProt NCBI
E2F3	Transcription factor E2F3 (E2F-3)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1362300	3.35937684363e-23	0.642857142857	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37 RBL1	Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
REAC:R-HSA-1362277	3.26037804629e-22	0.642857142857	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37 RBL1	Transcription of E2F targets under negative control by DREAM complex
REAC:R-HSA-1538133	2.0901098134e-20	0.642857142857	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37 RBL1	G0 and Early G1
REAC:R-HSA-69205	3.13419782733e-20	0.642857142857	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37 RBL1	G1/S-Specific Transcription
REAC:R-HSA-453279	7.26634450357e-18	0.785714285714	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 LIN37 LIN9 RBL1	Mitotic G1 phase and G1/S transition
KEGG:04218	2.53102495153e-16	0.714285714286	LIN54 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 LIN37 LIN9 RBL1	Cellular senescence
REAC:R-HSA-69231	4.21272429116e-15	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	Cyclin D associated events in G1
REAC:R-HSA-69236	4.21272429116e-15	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	G1 Phase
WP:WP5180	6.94949181187e-15	0.571428571429	LIN54 TFDP2 E2F4 LIN9 RBL2 RBL1 E2F5 LIN37	DYRK1A involvement regarding cell proliferation in brain development
CORUM:5596	1.12844696421e-13	0.357142857143	RBL2 LIN54 E2F4 LIN9 LIN37	LINC complex, quiescent cells
REAC:R-HSA-69206	1.42612715543e-13	0.642857142857	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37 RBL1	G1/S Transition
REAC:R-HSA-69202	5.67887406218e-13	0.571428571429	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37	Cyclin E associated events during G1/S transition
REAC:R-HSA-69656	6.94106654788e-13	0.571428571429	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37	Cyclin A:Cdk2-associated events at S phase entry
WP:WP179	4.14789515762e-12	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	Cell cycle
REAC:R-HSA-69278	1.09855359273e-11	0.785714285714	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 LIN37 LIN9 RBL1	Cell Cycle, Mitotic
KEGG:04110	1.70746618998e-11	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	Cell cycle
REAC:R-HSA-1640170	1.0672356957e-10	0.785714285714	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 LIN37 LIN9 RBL1	Cell Cycle
REAC:R-HSA-69242	1.31208311403e-10	0.571428571429	LIN54 TFDP2 E2F4 LIN9 RBL2 E2F1 E2F5 LIN37	S Phase
CORUM:5589	1.3739312217e-10	0.285714285714	LIN54 RBL1 LIN9 LIN37	LINC complex, S-phase
REAC:R-HSA-6791312	1.21214970424e-07	0.357142857143	RBL2 E2F1 E2F4 RBL1 TFDP2	TP53 Regulates Transcription of Cell Cycle Genes
CORUM:5593	1.4600392795e-07	0.214285714286	LIN54 LIN37 LIN9	LINC core complex
GO:0005667	2.64812524329e-07	0.642857142857	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	transcription regulator complex
REAC:R-HSA-6804114	3.49673363548e-07	0.285714285714	RBL2 E2F4 RBL1 TFDP2	TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
REAC:R-HSA-9661069	3.49673363548e-07	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
REAC:R-HSA-9659787	3.49673363548e-07	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects
CORUM:5117	3.64803730192e-07	0.214285714286	RBL2 E2F4 E2F5	RBL2 complex (DNMT1, E2F4, E2F5, HDAC1, SUV39H1, RBL2)
CORUM:2975	3.64803730192e-07	0.214285714286	E2F5 RBL1 E2F4	SMAD3-E2F4/5-p107-DP1 complex
CORUM:5118	7.29195506708e-07	0.214285714286	RBL2 E2F4 E2F5	RBL2 complex (E2F4, E2F5, HDAC1, SUV39H1, P300, RBL2)
CORUM:1474	7.29195506708e-07	0.214285714286	E2F5 RBL1 E2F4	SMAD3/4-E2F4/5-p107-DP1 complex
REAC:R-HSA-2559585	5.95954170433e-06	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Oncogene Induced Senescence
REAC:R-HSA-9687139	7.61729342671e-06	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Aberrant regulation of mitotic cell cycle due to RB1 defects
REAC:R-HSA-2173796	8.56475807908e-06	0.285714285714	E2F5 E2F4 RBL1 TFDP2	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
REAC:R-HSA-9675126	9.59764691822e-06	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Diseases of mitotic cell cycle
REAC:R-HSA-2173793	3.32294016087e-05	0.285714285714	E2F5 E2F4 RBL1 TFDP2	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
WP:WP45	3.7747322566e-05	0.285714285714	TFDP2 E2F3 E2F1 E2F2	G1 to S cell cycle control
CORUM:5160	4.44741811353e-05	0.142857142857	RBL2 E2F4	E2F4-p130 complex
CORUM:5159	4.44741811353e-05	0.142857142857	RBL1 E2F4	E2F4-p107-cyclinE complex
GO:0010468	5.66599574672e-05	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of gene expression
GO:0010556	8.75853182006e-05	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of macromolecule biosynthetic process
REAC:R-HSA-156711	8.88307161819e-05	0.214285714286	LIN54 LIN37 LIN9	Polo-like kinase mediated events
GO:0031326	0.000119189450934	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of cellular biosynthetic process
WP:WP2446	0.000124644595149	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Retinoblastoma gene in cancer
GO:0009889	0.000129486701642	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of biosynthetic process
CORUM:1473	0.000133349500201	0.142857142857	RBL2 E2F5	E2F5-RB2-DP1 complex
CORUM:1661	0.000133349500201	0.142857142857	RBL1 E2F4	E2F4-p107-cyclinA complex
CORUM:5144	0.000133349500201	0.142857142857	RBL1 E2F1	E2F1-p107-cyclinA complex
REAC:R-HSA-453274	0.000184892013153	0.357142857143	LIN54 E2F3 E2F1 LIN9 LIN37	Mitotic G2-G2/M phases
KEGG:04934	0.000265695773703	0.285714285714	POMC E2F3 E2F1 E2F2	Cushing syndrome
KEGG:05219	0.000272745512488	0.214285714286	E2F3 E2F1 E2F2	Bladder cancer
WP:WP236	0.000299433472118	0.285714285714	RBL2 E2F4 RBL1 E2F1	Adipogenesis
REAC:R-HSA-170834	0.000314712056409	0.285714285714	E2F5 E2F4 RBL1 TFDP2	Signaling by TGF-beta Receptor Complex
CORUM:1471	0.000444011791638	0.142857142857	RBL2 E2F5	pRb2/p130-multimolecular complex (RB2, E2F5, HDAC1, SUV39H1, P300)
WP:WP366	0.000457715973322	0.285714285714	RBL2 E2F4 RBL1 E2F5	TGF beta signaling pathway
CORUM:6444	0.000665653089703	0.142857142857	RBL2 RBL1	SMAR1-HDAC1-SIN3A-SIN3B-p107-p130 repressor complex
REAC:R-HSA-2559580	0.000721668312014	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Oxidative Stress Induced Senescence
REAC:R-HSA-9006936	0.000749013011324	0.285714285714	E2F5 E2F4 RBL1 TFDP2	Signaling by TGFB family members
GO:0006355	0.000788933082668	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	regulation of DNA-templated transcription
GO:2001141	0.000846654387404	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	regulation of RNA biosynthetic process
GO:0090575	0.000967961668366	0.428571428571	TFDP2 E2F2 E2F4 E2F1 E2F5 E2F3	RNA polymerase II transcription regulator complex
GO:0006351	0.00137134257161	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	DNA-templated transcription
KEGG:05218	0.00142363582364	0.214285714286	E2F3 E2F1 E2F2	Melanoma
GO:0060255	0.00145872195164	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of macromolecule metabolic process
GO:0031323	0.00150774426676	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of cellular metabolic process
GO:0032774	0.00155322980949	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	RNA biosynthetic process
KEGG:05214	0.00188009856862	0.214285714286	E2F3 E2F1 E2F2	Glioma
KEGG:05223	0.00188009856862	0.214285714286	E2F3 E2F1 E2F2	Non-small cell lung cancer
GO:0001067	0.0019477802701	0.642857142857	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	transcription regulatory region nucleic acid binding
GO:0010467	0.00222841955465	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	gene expression
KEGG:05212	0.00223233650819	0.214285714286	E2F3 E2F1 E2F2	Pancreatic cancer
REAC:R-HSA-111448	0.00238968144039	0.142857142857	TFDP2 E2F1	Activation of NOXA and translocation to mitochondria
REAC:R-HSA-68911	0.00238968144039	0.142857142857	E2F1 E2F3	G2 Phase
KEGG:05220	0.00242363230796	0.214285714286	E2F3 E2F1 E2F2	Chronic myeloid leukemia
WP:WP4685	0.0027024073326	0.214285714286	E2F3 E2F1 E2F2	Melanoma
GO:0051252	0.00290276006824	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	regulation of RNA metabolic process
GO:0001216	0.0030114918032	0.428571428571	TFDP2 E2F2 E2F4 E2F1 E2F5 E2F3	DNA-binding transcription activator activity
REAC:R-HSA-3700989	0.0030422249011	0.357142857143	RBL2 E2F1 E2F4 RBL1 TFDP2	Transcriptional Regulation by TP53
KEGG:01522	0.00329612652804	0.214285714286	E2F3 E2F1 E2F2	Endocrine resistance
WP:WP4255	0.00376819179791	0.214285714286	E2F3 E2F1 E2F2	Non small cell lung cancer
KEGG:05222	0.00380039958933	0.214285714286	E2F3 E2F1 E2F2	Small cell lung cancer
KEGG:04350	0.00393390270727	0.214285714286	E2F5 RBL1 E2F4	TGF-beta signaling pathway
GO:0003677	0.00431045510111	0.714285714286	LIN54 TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 LIN9 RBL1	DNA binding
KEGG:05215	0.00435276586086	0.214285714286	E2F3 E2F1 E2F2	Prostate cancer
GO:0019222	0.00480489848175	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	regulation of metabolic process
REAC:R-HSA-2559583	0.00508554984912	0.285714285714	TFDP2 E2F3 E2F1 E2F2	Cellular Senescence
REAC:R-HSA-212436	0.00508862541941	0.5	RBL2 TFDP2 E2F4 POMC E2F1 E2F5 RBL1	Generic Transcription Pathway
WP:WP53	0.0065190163061	0.142857142857	RBL2 RBL1	ID signaling pathway
WP:WP4263	0.00665832680083	0.214285714286	E2F3 E2F1 E2F2	Pancreatic adenocarcinoma pathway
GO:0034654	0.00667701850949	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	nucleobase-containing compound biosynthetic process
GO:0009059	0.00703141324807	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	macromolecule biosynthetic process
CORUM:5614	0.00753462493182	0.142857142857	RBL2 RBL1	Emerin complex 32
GO:0018130	0.00824679764186	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	heterocycle biosynthetic process
GO:0019438	0.00834882837684	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	aromatic compound biosynthetic process
GO:0019219	0.0083830929296	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	regulation of nucleobase-containing compound metabolic process
REAC:R-HSA-139915	0.00858403131057	0.142857142857	TFDP2 E2F1	Activation of PUMA and translocation to mitochondria
WP:WP4658	0.00882246767259	0.214285714286	E2F3 E2F1 E2F2	Small cell lung cancer
REAC:R-HSA-73857	0.010433823826	0.5	RBL2 TFDP2 E2F4 POMC E2F1 E2F5 RBL1	RNA Polymerase II Transcription
GO:1901362	0.0116697820233	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	organic cyclic compound biosynthetic process
KEGG:05224	0.012096046058	0.214285714286	E2F3 E2F1 E2F2	Breast cancer
KEGG:05226	0.0132550197928	0.214285714286	E2F3 E2F1 E2F2	Gastric cancer
KEGG:05160	0.0132550197928	0.214285714286	E2F3 E2F1 E2F2	Hepatitis C
REAC:R-HSA-1912408	0.013259733202	0.214285714286	TFDP2 E2F1 E2F3	Pre-NOTCH Transcription and Translation
GO:0006357	0.0158136219481	0.714285714286	TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9	regulation of transcription by RNA polymerase II
REAC:R-HSA-113501	0.0185580458088	0.142857142857	TFDP2 E2F1	Inhibition of replication initiation of damaged DNA by RB1/E2F1
KEGG:05161	0.0189814300125	0.214285714286	E2F3 E2F1 E2F2	Hepatitis B
KEGG:05206	0.0189814300125	0.214285714286	E2F3 E2F1 E2F2	MicroRNAs in cancer
GO:0000977	0.0214026527122	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	RNA polymerase II transcription regulatory region sequence-specific DNA binding
KEGG:05225	0.0234232001825	0.214285714286	E2F3 E2F1 E2F2	Hepatocellular carcinoma
REAC:R-HSA-1912422	0.0234730904617	0.214285714286	TFDP2 E2F1 E2F3	Pre-NOTCH Expression and Processing
REAC:R-HSA-74160	0.0235063164902	0.5	RBL2 TFDP2 E2F4 POMC E2F1 E2F5 RBL1	Gene expression (Transcription)
WP:000000	0.0255572149878	0.928571428571	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	WIKIPATHWAYS
GO:0006366	0.0262705597273	0.714285714286	TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9	transcription by RNA polymerase II
KEGG:05167	0.0275177525526	0.214285714286	E2F3 E2F1 E2F2	Kaposi sarcoma-associated herpesvirus infection
WP:WP4262	0.0290458239692	0.214285714286	E2F3 E2F1 E2F2	Breast cancer pathway
KEGG:05169	0.0336568278998	0.214285714286	E2F3 E2F1 E2F2	Epstein-Barr virus infection
GO:0000785	0.0389512163615	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	chromatin
GO:0016070	0.0392907399865	0.857142857143	LIN54 TFDP2 E2F4 E2F2 POMC E2F1 MCIDAS E2F5 E2F3 LIN37 LIN9 TESMIN	RNA metabolic process
KEGG:05163	0.040612882765	0.214285714286	E2F3 E2F1 E2F2	Human cytomegalovirus infection
GO:0000976	0.0411498000101	0.571428571429	TFDP2 E2F4 E2F2 RBL2 E2F1 E2F5 E2F3 RBL1	transcription cis-regulatory region binding
GO:0044249	0.0429321940113	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	cellular biosynthetic process
KEGG:05166	0.0444106258153	0.214285714286	E2F3 E2F1 E2F2	Human T-cell leukemia virus 1 infection
GO:1901576	0.0481113191273	1.0	MCIDAS RBL2 TFDP2 E2F4 E2F2 POMC TESMIN E2F1 LIN54 E2F5 E2F3 LIN37 LIN9 RBL1	organic substance biosynthetic process
WP:WP5202	0.0484579411248	0.142857142857	TFDP2 E2F4	Alstrom syndrome
CORUM:839	0.0499958217778	0.0714285714286	LIN9	LIN9-BMYB complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
LIN37	LIN54	1.0	0.148
LIN37	LIN9	1.0	0.174
LIN52	LIN9	1.0	0.198
LIN37	MYBL2	1.0	0.164
LIN54	LIN9	1.0	0.324
LIN52	LIN37	1.0	0.18
MYBL2	LIN9	1.0	0.248
MYBL1	LIN9	0.999
LIN37	MYBL1	0.999
LIN52	MYBL1	0.999
E2F4	TFDP2	0.998	0.16
LIN52	LIN54	0.998	0.21
E2F5	TFDP2	0.998		structurally_consistent (dimer)
TFDP2	E2F2	0.997		structurally_consistent (dimer)
LIN54	MYBL1	0.997
RBL2	RBL1	0.996	0.118
TFDP2	E2F3	0.996	0.152
TFDP2	E2F1	0.991		structurally_consistent (dimer)
LIN52	MYBL2	0.99	0.184
MCIDAS	TFDP2	0.985
LIN37	E2F5	0.983
LIN37	TESMIN	0.976
LIN9	TESMIN	0.976
E2F4	E2F5	0.974
LIN9	TFDP2	0.972	0.226
E2F4	LIN37	0.969	0.146
LIN37	TFDP2	0.967	0.164
LIN37	RBL1	0.967	0.16
RBL2	TFDP2	0.967	0.122
MYBL2	MYBL1	0.967
LIN54	TFDP2	0.966	0.182
RBL1	TFDP2	0.966	0.158
RBL2	LIN37	0.965	0.08
LIN54	MYBL2	0.965	0.206
LIN52	TFDP2	0.962	0.2
RBL1	LIN9	0.962	0.184
E2F2	E2F3	0.961
RBL2	LIN9	0.96	0.122
E2F5	E2F2	0.959		mutually_exclusive (Q14188)
POMC	E2F4	0.95
E2F4	LIN9	0.941	0.108
E2F4	E2F3	0.936	0.174
E2F5	E2F3	0.924
E2F4	E2F2	0.917
MCIDAS	E2F2	0.902
MCIDAS	E2F3	0.902
LIN52	E2F2	0.902
LIN9	E2F2	0.892
LIN52	MCIDAS	0.892
MCIDAS	E2F5	0.892
LIN54	E2F2	0.869
E2F4	MCIDAS	0.76
LIN9	MCIDAS	0.754
LIN54	MCIDAS	0.715
RBL1	E2F2	0.703
LIN52	E2F3	0.688	0.138
RBL2	E2F2	0.676
TESMIN	TFDP2	0.634
E2F4	TESMIN	0.634
LIN54	E2F5	0.633
RBL2	TESMIN	0.633
LIN52	E2F5	0.633
RBL1	TESMIN	0.633
LIN54	TESMIN	0.633
MYBL1	TESMIN	0.633
LIN52	TESMIN	0.633
MYBL2	TESMIN	0.633
RBL2	MYBL2	0.616	0.12
RBL1	MYBL1	0.616
MYBL2	TFDP2	0.616	0.218
MYBL1	TFDP2	0.616
RBL2	MYBL1	0.616
E2F4	MYBL2	0.616	0.214
E2F4	MYBL1	0.616
MYBL2	RBL1	0.616	0.238
E2F1	E2F3	0.582
E2F1	E2F2	0.568		mutually_exclusive (Q14188)
E2F5	E2F1	0.541
E2F4	RBL1	0.526	0.154
E2F4	RBL2	0.524	0.09	structurally_consistent (dimer)
RBL1	E2F3	0.468	0.138
RBL1	MCIDAS	0.455
LIN9	E2F5	0.428
TESMIN	E2F5	0.418
RBL2	E2F3	0.418	0.12
RBL2	MCIDAS	0.405
LIN52	RBL2	0.404	0.066
LIN52	RBL1	0.404	0.108
RBL2	E2F5	0.404		structurally_consistent (dimer)
E2F4	LIN52	0.404	0.128
MYBL1	E2F5	0.388
MYBL2	E2F5	0.388
RBL1	E2F5	0.384
E2F4	E2F1	0.378
LIN54	RBL1	0.372	0.206
RBL2	LIN54	0.36	0.128
LIN9	E2F3	0.357	0.162
E2F4	LIN54	0.352	0.11
LIN54	E2F3	0.341	0.17
MCIDAS	E2F1	0.214
LIN52	E2F1	0.214
RBL1	E2F1	0.146
LIN9	E2F1	0.131
RBL2	E2F1	0.131
LIN54	E2F1	0.108
MYBL2	E2F3	0.022	0.138

Related Complexes

Genename	Complexes
POMC	huMAP3_00125.1 huMAP3_01085.1 huMAP3_09732.1 huMAP3_10910.1 huMAP3_11725.1 huMAP3_11930.1
RBL2	huMAP3_00487.1 huMAP3_03477.1 huMAP3_05947.1 huMAP3_06587.1 huMAP3_08026.1 huMAP3_09145.1 huMAP3_10449.1 huMAP3_10674.1 huMAP3_10910.1 huMAP3_11168.1 huMAP3_12923.1 huMAP3_14722.1
E2F5	huMAP3_03477.1 huMAP3_04355.1 huMAP3_05947.1 huMAP3_06412.1 huMAP3_06587.1 huMAP3_08377.1 huMAP3_09319.1 huMAP3_10449.1 huMAP3_10910.1 huMAP3_11168.1 huMAP3_13863.1 huMAP3_14722.1
RBL1	huMAP3_00487.1 huMAP3_03164.1 huMAP3_03477.1 huMAP3_05269.1 huMAP3_05947.1 huMAP3_06587.1 huMAP3_08026.1 huMAP3_09145.1 huMAP3_10449.1 huMAP3_10674.1 huMAP3_10910.1 huMAP3_11168.1 huMAP3_12894.1 huMAP3_12923.1 huMAP3_14722.1
TFDP2	huMAP3_04355.1 huMAP3_05947.1 huMAP3_06412.1 huMAP3_10910.1 huMAP3_11168.1 huMAP3_14051.1
E2F1	huMAP3_04355.1 huMAP3_05947.1 huMAP3_06412.1 huMAP3_10910.1 huMAP3_11168.1 huMAP3_14051.1
E2F4	huMAP3_00125.1 huMAP3_03477.1 huMAP3_06587.1 huMAP3_08377.1 huMAP3_09319.1 huMAP3_10449.1 huMAP3_10910.1 huMAP3_11168.1
LIN52	huMAP3_00487.1 huMAP3_03164.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
LIN37	huMAP3_00487.1 huMAP3_03164.1 huMAP3_06412.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
LIN54	huMAP3_00487.1 huMAP3_03164.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
E2F2	huMAP3_04355.1 huMAP3_05947.1 huMAP3_06412.1 huMAP3_10910.1 huMAP3_11168.1
TESMIN	huMAP3_00487.1 huMAP3_01559.1 huMAP3_03164.1 huMAP3_08170.1 huMAP3_10910.1
MYBL2	huMAP3_00487.1 huMAP3_03164.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
MYBL1	huMAP3_00487.1 huMAP3_03164.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
MCIDAS	huMAP3_02716.1 huMAP3_04355.1 huMAP3_05947.1 huMAP3_06412.1 huMAP3_10910.1 huMAP3_11168.1
LIN9	huMAP3_00487.1 huMAP3_03164.1 huMAP3_07470.1 huMAP3_08170.1 huMAP3_10910.1 huMAP3_11168.1
E2F3	huMAP3_04355.1 huMAP3_05947.1 huMAP3_10910.1 huMAP3_11168.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_10910.1

Complex Portal: CPX-21932