hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10914.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ETF1 | Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1) | 5 | UniProt NCBI |
| PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) | 5 | UniProt NCBI |
| BLVRB | Flavin reductase (NADPH) (FR) (EC 1.5.1.30) (Biliverdin reductase B) (BVR-B) (EC 1.3.1.24) (Biliverdin-IX beta-reductase) (Green heme-binding protein) (GHBP) (NADPH-dependent diaphorase) (NADPH-flavin reductase) (FLR) | 5 | UniProt NCBI |
| UBE2L3 | Ubiquitin-conjugating enzyme E2 L3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L3) (L-UBC) (UbcH7) (Ubiquitin carrier protein L3) (Ubiquitin-conjugating enzyme E2-F1) (Ubiquitin-protein ligase L3) | 5 | UniProt NCBI |
| GMPS | GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:809 | 0.0249718442456 | 0.25 | ETF1 | eRF1-eRF3-GTP-Mg(2+) complex |
| CORUM:3183 | 0.0249718442456 | 0.25 | PTPN11 | PDGFRA-SHP-2 complex, PDGF stimulated |
| CORUM:3186 | 0.049938562206 | 0.25 | PTPN11 | GRB2-SHP-2 complex, PDGF stimulated |
| CORUM:7441 | 0.049938562206 | 0.25 | PTPN11 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PTPN11 | BLVRB | 0.989 | 0.074 | bioplex_WMM bioplex3_WMM fraction |
| PTPN11 | GMPS | 0.986 | 0.174 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| PTPN11 | ETF1 | 0.973 | 0.186 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| GMPS | UBE2L3 | 0.971 | 0.234 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| GMPS | BLVRB | 0.953 | 0.012 | bioplex_WMM bioplex3_WMM fraction |
| ETF1 | BLVRB | 0.883 | 0.026 | bioplex_WMM bioplex3_WMM WMM_only |
| GMPS | ETF1 | 0.877 | 0.332 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM treiber_WMM WMM_only |
| UBE2L3 | BLVRB | 0.327 | 0.054 | bioplex_WMM bioplex3_WMM fraction treiber_WMM |
| PTPN11 | UBE2L3 | 0.043 | 0.31 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| ETF1 | UBE2L3 | 0.028 | 0.304 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes