hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10922.1
Complex Portal: CPX-22240
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EEF2KMT | Protein-lysine N-methyltransferase EEF2KMT (EC 2.1.1.-) (eEF2-lysine methyltransferase) (eEF2-KMT) | 5 | UniProt NCBI |
| TRMT11 | tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) | 4 | UniProt NCBI |
| LPL | Lipoprotein lipase (LPL) (EC 3.1.1.34) (Phospholipase A1) (EC 3.1.1.32) | 5 | UniProt NCBI |
| GALC | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | 5 | UniProt NCBI |
| TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6782315 | 0.0100756681589 | 0.4 | TRMT11 TRMT112 | tRNA modification in the nucleus and cytosol |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TRMT112 | TRMT11 | 0.998 | 0.05 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM |
| EEF2KMT | LPL | 0.998 | 0.098 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GALC | TRMT11 | 0.99 | 0.04 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| EEF2KMT | GALC | 0.978 | 0.048 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GALC | TRMT112 | 0.447 | 0.034 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| GALC | LPL | 0.042 | 0.082 | bioplex3_WMM WMM_only |
Related Complexes