hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10932.1
Complex Portal: CPX-23502
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NPTXR | Neuronal pentraxin receptor | 3 | UniProt NCBI |
| FGF19 | Fibroblast growth factor 19 (FGF-19) | 5 | UniProt NCBI |
| NPTX1 | Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) | 5 | UniProt NCBI |
| NPTX2 | Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0100152 | 0.000156692671033 | 0.5 | NPTXR NPTX1 | cerebral cortex; synapses[>=Medium] |
| HPA:0100151 | 0.000195847962419 | 0.5 | NPTXR NPTX1 | cerebral cortex; synapses[>=Low] |
| GO:0098978 | 0.0183580179548 | 0.75 | NPTXR NPTX1 NPTX2 | glutamatergic synapse |
| HPA:0100153 | 0.0212163885994 | 0.25 | NPTX1 | cerebral cortex; synapses[High] |
| CORUM:6832 | 0.0249718442456 | 0.25 | FGF19 | FGF19-FGFR4-KLB complex, heparin induced |
| HPA:0250153 | 0.0424284218432 | 0.25 | NPTX1 | hippocampus; synapses[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NPTX2 | NPTXR | 0.994 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| FGF19 | NPTX1 | 0.98 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NPTXR | NPTX1 | 0.98 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NPTX2 | NPTX1 | 0.893 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| FGF19 | NPTXR | 0.255 | bioplex3_WMM WMM_only | ||
| FGF19 | NPTX2 | 0.043 | bioplex3_WMM WMM_only |
Related Complexes