hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10938.1
Complex Portal: CPX-11445
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KBTBD7 | Kelch repeat and BTB domain-containing protein 7 | 5 | UniProt NCBI |
| METTL15 | 12S rRNA N4-methylcytidine (m4C) methyltransferase (12S rRNA m4C methyltransferase) (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) (Methyltransferase-like protein 15) | 5 | UniProt NCBI |
| KBTBD8 | Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP) | 5 | UniProt NCBI |
| GREM2 | Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus) | 5 | UniProt NCBI |
| DOK4 | Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5) | 5 | UniProt NCBI |
| CDX1 | Homeobox protein CDX-1 (Caudal-type homeobox protein 1) | 5 | UniProt NCBI |
| PDZD11 | PDZ domain-containing protein 11 (ATPase-interacting PDZ protein) (Plasma membrane calcium ATPase-interacting single-PDZ protein) (PMCA-interacting single-PDZ protein) | 5 | UniProt NCBI |
| RBFA | Putative ribosome-binding factor A, mitochondrial | 5 | UniProt NCBI |
| TEFM | Transcription elongation factor, mitochondrial | 5 | UniProt NCBI |
| KBTBD6 | Kelch repeat and BTB domain-containing protein 6 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KBTBD7 | KBTBD6 | 1.0 | 0.246 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| KBTBD7 | TEFM | 0.999 | 0.138 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| METTL15 | RBFA | 0.999 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KBTBD7 | RBFA | 0.999 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| DOK4 | PDZD11 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| CDX1 | KBTBD6 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KBTBD7 | CDX1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KBTBD7 | GREM2 | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GREM2 | KBTBD6 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KBTBD7 | KBTBD8 | 0.975 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KBTBD7 | DOK4 | 0.965 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DOK4 | KBTBD6 | 0.964 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| RBFA | KBTBD6 | 0.963 | 0.11 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TEFM | RBFA | 0.711 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| TEFM | KBTBD6 | 0.459 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KBTBD8 | TEFM | 0.237 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| KBTBD8 | RBFA | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KBTBD7 | METTL15 | 0.158 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KBTBD8 | KBTBD6 | 0.11 |
mutually_exclusive (Q8WVZ9)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| KBTBD8 | METTL15 | 0.088 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | |
| TEFM | METTL15 | 0.073 | 0.106 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| METTL15 | KBTBD6 | 0.025 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDZD11 | KBTBD6 | 0.013 | 0.09 | bioplex3_WMM gupta_WMM WMM_only | |
| KBTBD7 | PDZD11 | 0.004 | 0.134 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes