hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10939.1
Complex Portal: CPX-11046
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLHL28 | Kelch-like protein 28 (BTB/POZ domain-containing protein 5) | 2 | UniProt NCBI |
| BTBD7 | BTB/POZ domain-containing protein 7 | 4 | UniProt NCBI |
| USP25 | Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) | 5 | UniProt NCBI |
| KLHL20 | Kelch-like protein 20 (Kelch-like ECT2-interacting protein) (Kelch-like protein X) | 5 | UniProt NCBI |
| IPP | Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27) | 4 | UniProt NCBI |
| FBXL17 | F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13) | 5 | UniProt NCBI |
| CCIN | Calicin | 4 | UniProt NCBI |
| NUDCD3 | NudC domain-containing protein 3 | 5 | UniProt NCBI |
| KLHL13 | Kelch-like protein 13 (BTB and kelch domain-containing protein 2) | 5 | UniProt NCBI |
| KLHL26 | Kelch-like protein 26 | 5 | UniProt NCBI |
| KLHL9 | Kelch-like protein 9 | 5 | UniProt NCBI |
| KLHL14 | Kelch-like protein 14 (Protein interactor of Torsin-1A) (Printor) (Protein interactor of torsinA) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7523 | 0.000225350794349 | 0.166666666667 | KLHL9 KLHL13 | Ubiquitin E3 ligase (CUL3, KLHL9, KLHL13, RBX1) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| IPP | KLHL28 | 0.999 | ||
| NUDCD3 | KLHL28 | 0.999 |
structurally_consistent (Q53HC5)
|
|
| BTBD7 | KLHL14 | 0.999 | ||
| KLHL13 | KLHL28 | 0.999 |
structurally_consistent (dimer)
|
|
| KLHL14 | KLHL28 | 0.998 | ||
| KLHL26 | KLHL28 | 0.998 |
structurally_consistent (dimer)
|
|
| KLHL26 | KLHL14 | 0.998 | ||
| KLHL13 | KLHL9 | 0.998 | 0.19 |
structurally_consistent (dimer)
|
| NUDCD3 | KLHL26 | 0.998 | 0.068 |
structurally_consistent (dimer)
|
| KLHL9 | KLHL28 | 0.998 |
structurally_consistent (dimer)
|
|
| FBXL17 | KLHL28 | 0.997 | ||
| NUDCD3 | KLHL14 | 0.995 | ||
| NUDCD3 | KLHL9 | 0.995 | 0.105 | |
| FBXL17 | NUDCD3 | 0.995 | 0.086 | |
| IPP | KLHL20 | 0.994 | ||
| IPP | KLHL9 | 0.993 | ||
| FBXL17 | KLHL9 | 0.989 | 0.082 | |
| KLHL20 | KLHL26 | 0.988 |
structurally_consistent (dimer)
|
|
| NUDCD3 | KLHL20 | 0.985 |
structurally_consistent (Q53HC5)
|
|
| KLHL26 | KLHL9 | 0.981 | 0.098 |
structurally_consistent (dimer)
|
| FBXL17 | KLHL13 | 0.981 | 0.106 | |
| FBXL17 | KLHL14 | 0.979 | ||
| USP25 | KLHL9 | 0.977 | 0.2 | |
| KLHL13 | KLHL14 | 0.976 | ||
| IPP | KLHL26 | 0.976 |
structurally_consistent (dimer)
|
|
| FBXL17 | KLHL20 | 0.975 | ||
| IPP | NUDCD3 | 0.973 | ||
| CCIN | NUDCD3 | 0.954 | ||
| KLHL26 | KLHL13 | 0.945 | 0.088 | |
| KLHL9 | KLHL14 | 0.919 | ||
| FBXL17 | KLHL26 | 0.901 | 0.136 | |
| IPP | KLHL14 | 0.901 | ||
| FBXL17 | IPP | 0.858 | ||
| KLHL13 | USP25 | 0.815 | 0.166 | |
| BTBD7 | KLHL28 | 0.703 | ||
| IPP | KLHL13 | 0.501 | ||
| KLHL20 | KLHL28 | 0.496 | ||
| IPP | BTBD7 | 0.468 | ||
| FBXL17 | BTBD7 | 0.468 | ||
| USP25 | KLHL28 | 0.343 | ||
| IPP | USP25 | 0.312 | ||
| FBXL17 | USP25 | 0.312 | 0.094 | |
| NUDCD3 | KLHL13 | 0.296 | 0.038 | |
| NUDCD3 | BTBD7 | 0.22 | ||
| KLHL26 | BTBD7 | 0.22 | ||
| KLHL13 | BTBD7 | 0.16 | ||
| KLHL26 | USP25 | 0.159 | 0.146 | |
| NUDCD3 | USP25 | 0.139 | 0.05 | |
| KLHL9 | BTBD7 | 0.12 | ||
| KLHL20 | KLHL13 | 0.041 |
structurally_consistent (Q9P2J3)
|
|
| KLHL20 | KLHL9 | 0.033 |
structurally_consistent (dimer)
|
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