hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10949.1
Complex Portal: CPX-18041
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RLN2 | Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain] | 5 | UniProt NCBI |
| NMS | Neuromedin-S | 3 | UniProt NCBI |
| ACTN3 | Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) | 5 | UniProt NCBI |
| RLN1 | Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain] | 4 | UniProt NCBI |
| BACE1 | Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04080 | 0.000982001084064 | 0.6 | RLN2 RLN1 NMS | Neuroactive ligand-receptor interaction |
| KEGG:04926 | 0.0258857078716 | 0.4 | RLN2 RLN1 | Relaxin signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RLN2 | ACTN3 | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NMS | BACE1 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| RLN2 | RLN1 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| BACE1 | RLN1 | 0.975 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| BACE1 | RLN2 | 0.113 | bioplex3_WMM WMM_only | ||
| RLN1 | ACTN3 | 0.042 | bioplex3_WMM WMM_only |
Related Complexes