hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10953.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADCYAP1 | Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) (PACAP38)] | 5 | UniProt NCBI |
| MMP10 | Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) | 5 | UniProt NCBI |
| PCSK1N | ProSAAS (Proprotein convertase subtilisin/kexin type 1 inhibitor) (Proprotein convertase 1 inhibitor) (pro-SAAS) [Cleaved into: KEP; Big SAAS (b-SAAS); Little SAAS (l-SAAS) (N-proSAAS); Big PEN-LEN (b-PEN-LEN) (SAAS CT(1-49)); PEN; Little LEN (l-LEN); Big LEN (b-LEN) (SAAS CT(25-40))] | 5 | UniProt NCBI |
| OPTC | Opticin (Oculoglycan) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0370493 | 0.00176392100455 | 0.5 | ADCYAP1 PCSK1N | pituitary gland; cells in anterior [High] |
| HPA:0370492 | 0.00305176668958 | 0.5 | ADCYAP1 PCSK1N | pituitary gland; cells in anterior [>=Medium] |
| HPA:0370000 | 0.00321643312522 | 0.5 | ADCYAP1 PCSK1N | pituitary gland |
| HPA:0370491 | 0.00321643312522 | 0.5 | ADCYAP1 PCSK1N | pituitary gland; cells in anterior [>=Low] |
| REAC:R-HSA-187015 | 0.0499436884912 | 0.25 | ADCYAP1 | Activation of TRKA receptors |
| REAC:R-HSA-187024 | 0.0499436884912 | 0.25 | ADCYAP1 | NGF-independant TRKA activation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PCSK1N | MMP10 | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCSK1N | ADCYAP1 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PCSK1N | OPTC | 0.959 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes