hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10960.1

Complex Portal: CPX-19875

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
BICDL2	BICD family-like cargo adapter 2 (Bicaudal D-related protein 2) (BICD-related protein 2) (BICDR-2) (Coiled-coil domain-containing protein 64B)	4	UniProt NCBI
DES	Desmin	5	UniProt NCBI
IDE	Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)	5	UniProt NCBI
INA	Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)	5	UniProt NCBI
KRT7	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)	5	UniProt NCBI
NEFH	Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein)	5	UniProt NCBI
NEFL	Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)	5	UniProt NCBI
NEFM	Neurofilament medium polypeptide (NF-M) (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)	5	UniProt NCBI
NES	Nestin	5	UniProt NCBI
SYNC	Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0045103	2.64238714844e-17	0.9	NES SYNC VIM NEFL SYNM INA KRT7 DES NEFM	intermediate filament-based process
GO:0045104	3.26846874258e-14	0.8	NES VIM NEFL SYNM INA KRT7 DES NEFM	intermediate filament cytoskeleton organization
GO:0005882	1.6798415771e-13	0.8	NES VIM NEFL SYNM INA KRT7 DES NEFM	intermediate filament
GO:0045111	4.40113533035e-12	0.8	NES VIM NEFL SYNM INA KRT7 DES NEFM	intermediate filament cytoskeleton
GO:0045109	2.12777722143e-09	0.6	VIM NEFL INA KRT7 DES NEFM	intermediate filament organization
GO:0099512	7.69867640783e-08	0.9	NES SYNC VIM NEFL SYNM INA KRT7 DES NEFM	supramolecular fiber
GO:0099081	8.61765833762e-08	0.9	NES SYNC VIM NEFL SYNM INA KRT7 DES NEFM	supramolecular polymer
GO:0005200	4.74036470012e-07	0.6	NEFL SYNM INA VIM DES NEFM	structural constituent of cytoskeleton
GO:0099513	9.14412176003e-07	0.8	NES VIM NEFL SYNM INA KRT7 DES NEFM	polymeric cytoskeletal fiber
GO:0099080	4.36294495548e-06	0.9	NES SYNC VIM NEFL SYNM INA KRT7 DES NEFM	supramolecular complex

Showing 1 to 10 of 25 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
NEFM	DES	1.0	0.054
NEFM	NES	1.0	0.116
NEFL	NEFM	0.999	0.236
SYNC	DES	0.999
VIM	DES	0.999	0.238
NEFM	VIM	0.999	0.296
NES	DES	0.998	0.094
INA	NEFM	0.998	0.138
NEFM	SYNC	0.997
SYNC	VIM	0.997

Showing 1 to 10 of 58 entries

Related Complexes

Genename	Complexes
INA	huMAP3_00659.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
DES	huMAP3_06939.1 huMAP3_10960.1 huMAP3_11715.1
SYNM	huMAP3_02709.1 huMAP3_04868.1 huMAP3_06939.1 huMAP3_10960.1 huMAP3_11715.1 huMAP3_12191.1 huMAP3_13447.1
NEFL	huMAP3_00659.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
NEFM	huMAP3_00659.1 huMAP3_06794.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
KRT7	huMAP3_05156.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
SYNC	huMAP3_02709.1 huMAP3_06292.1 huMAP3_06939.1 huMAP3_10960.1 huMAP3_11715.1
BICDL2	huMAP3_02709.1 huMAP3_03177.1 huMAP3_06939.1 huMAP3_09117.1 huMAP3_10960.1 huMAP3_11715.1
VIM	huMAP3_05156.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
IDE	huMAP3_00335.1 huMAP3_05156.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1 huMAP3_11831.1
NES	huMAP3_05156.1 huMAP3_07026.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_11715.1
NEFH	huMAP3_00659.1 huMAP3_06794.1 huMAP3_09417.1 huMAP3_10960.1 huMAP3_13014.1 huMAP3_15340.1