hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10967.1
Complex Portal: CPX-19534
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OXCT1 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase) | 5 | UniProt NCBI |
| ICAM5 | Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin) | 5 | UniProt NCBI |
| OXCT2 | Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (EC 2.8.3.5) (3-oxoacid CoA-transferase 2A) (Testis-specific succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-t) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-77108 | 4.09070097144e-05 | 0.666666666667 | OXCT1 OXCT2 | Utilization of Ketone Bodies |
| KEGG:00650 | 0.000228770921677 | 0.666666666667 | OXCT1 OXCT2 | Butanoate metabolism |
| REAC:R-HSA-74182 | 0.00024538606603 | 0.666666666667 | OXCT1 OXCT2 | Ketone body metabolism |
| KEGG:00280 | 0.000788502734463 | 0.666666666667 | OXCT1 OXCT2 | Valine, leucine and isoleucine degradation |
| GO:0008260 | 0.00140460216025 | 0.666666666667 | OXCT1 OXCT2 | succinyl-CoA:3-oxo-acid CoA-transferase activity |
| GO:0008410 | 0.00842684400117 | 0.666666666667 | OXCT1 OXCT2 | CoA-transferase activity |
| GO:0046950 | 0.0294899169624 | 0.666666666667 | OXCT1 OXCT2 | cellular ketone body metabolic process |
| WP:WP311 | 0.0413734636003 | 0.333333333333 | OXCT1 | Ketone bodies synthesis and degradation |
| WP:WP5175 | 0.0413734636003 | 0.333333333333 | OXCT1 | Disorders in ketone body synthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| OXCT2 | ICAM5 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| OXCT1 | OXCT2 | 0.971 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| OXCT1 | huMAP3_03698.1 huMAP3_10967.1 huMAP3_12408.1 huMAP3_14668.1 huMAP3_14868.1 |
| ICAM5 | huMAP3_09269.1 huMAP3_10967.1 huMAP3_11349.1 huMAP3_14668.1 |
| OXCT2 | huMAP3_03698.1 huMAP3_10967.1 huMAP3_14668.1 huMAP3_14868.1 |