hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_10974.1

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
APBB1	Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65)	5	UniProt NCBI
APBB2	Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1)	5	UniProt NCBI
APBB3	Amyloid-beta A4 precursor protein-binding family B member 3 (Protein Fe65-like 2) (Fe65L2)	5	UniProt NCBI
APLP1	Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]	5	UniProt NCBI
APLP2	Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II)	5	UniProt NCBI
APP	Amyloid-beta precursor protein (APP) (ABPP) (APPI) (Alzheimer disease amyloid A4 protein homolog) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta (A4) precursor protein) (Amyloid-beta A4 protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]	5	UniProt NCBI
CES2	Cocaine esterase (EC 3.1.1.84) (Carboxylesterase 2) (CE-2) (hCE-2) (EC 3.1.1.1) (Methylumbelliferyl-acetate deacetylase 2) (EC 3.1.1.56)	5	UniProt NCBI
QTRT1	Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase)	5	UniProt NCBI
RHOBTB2	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)	5	UniProt NCBI
SYDE1	Rho GTPase-activating protein SYDE1 (Synapse defective protein 1 homolog 1) (Protein syd-1 homolog 1)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:143	0.000112726824524	0.166666666667	APBB1 APP	APP-APBB1-LRP1 complex
CORUM:7577	0.000112726824524	0.166666666667	APBB1 APP	APP-APBB1-KAT5 complex
CORUM:2711	0.0499436884912	0.0833333333333	APP	Amyloid beta protein homo-oligomer complex
CORUM:6056	0.0499436884912	0.0833333333333	APP	APP-TNFRSF21 complex
CORUM:7529	0.0499436884912	0.0833333333333	APP	APP-Abeta42-VDAC1 complex

Showing 1 to 5 of 5 entries

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Protein 1	Protein 2	Score	ProteomeHD	Evidence
RHOBTB2	APBB3	1.0		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APBB2	APP	1.0	0.064	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM
APBB1	APP	0.999	0.07	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
APBB1	SYDE1	0.999	0.134	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
APBB1	APLP2	0.999	0.116	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APBB2	APLP2	0.999	0.102	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APBB3	APP	0.999		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APBB2	APLP1	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APBB3	APLP2	0.998		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
APP	CES2	0.996	0.082	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116

Showing 1 to 10 of 35 entries

Related Complexes

Genename	Complexes
SYDE1	huMAP3_06591.1 huMAP3_09272.1 huMAP3_10974.1 huMAP3_14687.1
RHOBTB2	huMAP3_00142.1 huMAP3_00723.1 huMAP3_03598.1 huMAP3_06792.1 huMAP3_10198.1 huMAP3_10887.1 huMAP3_10974.1 huMAP3_14528.1
APLP2	huMAP3_06797.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_10367.1 huMAP3_10974.1 huMAP3_14687.1
TAS1R2	huMAP3_02279.1 huMAP3_03181.1 huMAP3_04597.1 huMAP3_05410.1 huMAP3_10886.1 huMAP3_10974.1 huMAP3_11154.1 huMAP3_12207.1 huMAP3_12265.1 huMAP3_12416.1 huMAP3_12536.1 huMAP3_13791.1
APP	huMAP3_01640.1 huMAP3_10974.1
APBB1	huMAP3_00566.1 huMAP3_06591.1 huMAP3_06797.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_10974.1 huMAP3_14687.1
APBB3	huMAP3_00723.1 huMAP3_03598.1 huMAP3_10887.1 huMAP3_10974.1 huMAP3_14528.1 huMAP3_14687.1
APLP1	huMAP3_00723.1 huMAP3_06797.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_10887.1 huMAP3_10974.1 huMAP3_14687.1
QTRT1	huMAP3_03181.1 huMAP3_10974.1
SYDE2	huMAP3_00566.1 huMAP3_04537.1 huMAP3_06797.1 huMAP3_06971.1 huMAP3_08480.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_10974.1 huMAP3_12897.1 huMAP3_14687.1
APBB2	huMAP3_00566.1 huMAP3_06591.1 huMAP3_06797.1 huMAP3_08492.1 huMAP3_09272.1 huMAP3_10974.1 huMAP3_14687.1
CES2	huMAP3_01640.1 huMAP3_02642.1 huMAP3_03448.1 huMAP3_07879.1 huMAP3_08861.1 huMAP3_09695.1 huMAP3_10974.1 huMAP3_14537.1