hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10981.1
Complex Portal: CPX-21606
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPIL3 | Peptidyl-prolyl cis-trans isomerase-like 3 (PPIase) (EC 5.2.1.8) (Cyclophilin J) (CyPJ) (Cyclophilin-like protein PPIL3) (Rotamase PPIL3) | 5 | UniProt NCBI |
| GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma (Cytokine-responsive protein CR6) (DNA damage-inducible transcript 2 protein) (DDIT-2) | 5 | UniProt NCBI |
| MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAP three kinase 1) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) | 5 | UniProt NCBI |
| PTMA | Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4872 | 0.000232143427839 | 0.5 | GADD45G MAP3K4 | MAP3K1 role in promoting and blocking gonadal determination |
| CORUM:5546 | 0.049938562206 | 0.25 | GADD45G | CDC2-PCNA-CCNB1-GADD45G complex |
| CORUM:6989 | 0.049938562206 | 0.25 | PTMA | ProTalpha C9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAP3K4 | GADD45G | 1.0 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PPIL3 | PTMA | 0.978 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PPIL3 | MAP3K4 | 0.977 | 0.042 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| MAP3K4 | PTMA | 0.251 | 0.034 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes