hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10990.1
Complex Portal: CPX-19305
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADGRE2 | Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312) | 5 | UniProt NCBI |
| SLC18B1 | MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT) | 5 | UniProt NCBI |
| TMPRSS11B | Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5) | 5 | UniProt NCBI |
| WARS1 | Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS] | 5 | UniProt NCBI |
| GALNT1 | Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form] | 5 | UniProt NCBI |
| LMAN2L | VIP36-like protein (Lectin mannose-binding 2-like) (LMAN2-like protein) | 5 | UniProt NCBI |
| GALNT13 | Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00512 | 0.00235248417572 | 0.333333333333 | GALNT1 GALNT13 | Mucin type O-glycan biosynthesis |
| KEGG:00514 | 0.00563154229257 | 0.333333333333 | GALNT1 GALNT13 | Other types of O-glycan biosynthesis |
| REAC:R-HSA-913709 | 0.0276828753036 | 0.333333333333 | GALNT1 GALNT13 | O-linked glycosylation of mucins |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GALNT1 | GALNT13 | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ADGRE2 | TMPRSS11B | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GALNT1 | TMPRSS11B | 0.977 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LMAN2L | TMPRSS11B | 0.973 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLC18B1 | TMPRSS11B | 0.971 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| LMAN2L | WARS1 | 0.964 | 0.0361240694789 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ADGRE2 | LMAN2L | 0.784 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GALNT1 | LMAN2L | 0.299 | 0.054 |
structurally_consistent (Q86T26)
|
bioplex_WMM bioplex3_WMM WMM_only |
| ADGRE2 | SLC18B1 | 0.289 | bioplex3_WMM WMM_only | ||
| LMAN2L | SLC18B1 | 0.268 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| GALNT1 | SLC18B1 | 0.213 | 0.058 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| TMPRSS11B | GALNT13 | 0.161 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| LMAN2L | GALNT13 | 0.118 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ADGRE2 | GALNT1 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC18B1 | GALNT13 | 0.059 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ADGRE2 | GALNT13 | 0.026 | bioplex3_WMM WMM_only | ||
| GALNT1 | WARS1 | 0.014 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only | |
| WARS1 | GALNT13 | 0.012 | bioplex_WMM bioplex3_WMM WMM_only | ||
| WARS1 | SLC18B1 | 0.007 | 0.056 | bioplex3_WMM WMM_only |
Related Complexes