hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_10995.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UBE2T | Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T) | 5 | UniProt NCBI |
| TLN1 | Talin-1 | 5 | UniProt NCBI |
| CDV3 | Protein CDV3 homolog | 3 | UniProt NCBI |
| NHERF1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:682 | 0.0249718442456 | 0.25 | NHERF1 | C-CFTR-NHERF-ezrin complex |
| CORUM:687 | 0.0249718442456 | 0.25 | NHERF1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:2378 | 0.0249718442456 | 0.25 | TLN1 | ITGA2b-ITGB3-TLN1 complex |
| CORUM:6791 | 0.0249718442456 | 0.25 | NHERF1 | NHERF1-NPT2A-EZR complex |
| CORUM:6702 | 0.049938562206 | 0.25 | NHERF1 | CXCR2-NHERF1-PLC-beta-3 complex |
| CORUM:6788 | 0.049938562206 | 0.25 | NHERF1 | SLC9A3R1-ACTN4 complex |
| CORUM:6790 | 0.049938562206 | 0.25 | NHERF1 | NHERF1-PRKCZ complex |
| CORUM:6793 | 0.049938562206 | 0.25 | NHERF1 | PDZK1-NHERF1-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UBE2T | TLN1 | 0.993 | 0.102 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| UBE2T | NHERF1 | 0.99 | 0.028 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| UBE2T | CDV3 | 0.974 | 0.048 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CDV3 | NHERF1 | 0.891 | 0.064 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TLN1 | NHERF1 | 0.389 | 0.206 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| CDV3 | TLN1 | 0.362 | 0.146 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes