hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_10999.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| ORC6 | Origin recognition complex subunit 6 | 5 | UniProt NCBI |
| DDX42 | ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
| IFI27L1 | Interferon alpha-inducible protein 27-like protein 1 (Interferon-stimulated gene 12c protein) (ISG12(c)) (ISG12C) | 3 | UniProt NCBI |
| SFPQ | Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 0.000204640425412 | 0.4 | PSPC1 NONO | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| CORUM:330 | 0.0498708842806 | 0.2 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0498708842806 | 0.2 | NONO | TOP1-PSF-P54 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NONO | SFPQ | 1.0 | 0.992 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | NONO | 1.0 | 0.62 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| PSPC1 | SFPQ | 0.999 | 0.674 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| IFI27L1 | ORC6 | 0.979 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ORC6 | NONO | 0.972 | 0.22 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | DDX42 | 0.967 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | SFPQ | 0.959 | 0.12 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | PSPC1 | 0.957 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| DDX42 | PSPC1 | 0.674 | 0.224 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| DDX42 | SFPQ | 0.383 | 0.506 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| DDX42 | NONO | 0.262 | 0.376 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
| IFI27L1 | SFPQ | 0.203 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IFI27L1 | NONO | 0.167 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IFI27L1 | DDX42 | 0.1 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| IFI27L1 | PSPC1 | 0.096 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes