hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11004.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TLCD2 | TLC domain-containing protein 2 | 4 | UniProt NCBI |
| SLC9A6 | Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) | 5 | UniProt NCBI |
| SLC9A7 | Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-425986 | 0.000143154936711 | 0.666666666667 | SLC9A7 SLC9A6 | Sodium/Proton exchangers |
| KEGG:04260 | 0.00194494452342 | 0.666666666667 | SLC9A7 SLC9A6 | Cardiac muscle contraction |
| REAC:R-HSA-425393 | 0.0137071284674 | 0.666666666667 | SLC9A7 SLC9A6 | Transport of inorganic cations/anions and amino acids/oligopeptides |
| GO:0015386 | 0.0294899169624 | 0.666666666667 | SLC9A7 SLC9A6 | potassium:proton antiporter activity |
| REAC:R-HSA-5619092 | 0.0498224659464 | 0.333333333333 | SLC9A6 | Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC9A6 | SLC9A7 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLC9A6 | TLCD2 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SLC9A7 | TLCD2 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes