hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11012.1
Complex Portal: CPX-19451
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BICD2 | Protein bicaudal D homolog 2 (Bic-D 2) | 5 | UniProt NCBI |
| BORA | Protein aurora borealis (HsBora) | 5 | UniProt NCBI |
| PLK1 | Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2565942 | 0.0231174657298 | 0.666666666667 | BORA PLK1 | Regulation of PLK1 Activity at G2/M Transition |
| GO:0070507 | 0.0343879058955 | 1.0 | BICD2 PLK1 BORA | regulation of microtubule cytoskeleton organization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BORA | PLK1 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | ||
| BICD2 | PLK1 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM | ||
| BICD2 | BORA | 0.306 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| BICD2 | huMAP3_04929.1 huMAP3_10804.1 huMAP3_11012.1 huMAP3_13237.1 huMAP3_14578.1 |
| BORA | huMAP3_05221.1 huMAP3_11012.1 huMAP3_12079.1 huMAP3_13744.1 |
| PLK1 | huMAP3_05221.1 huMAP3_11012.1 huMAP3_12079.1 |