hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11023.1
Complex Portal: CPX-12003
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TRMT11 | tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) | 4 | UniProt NCBI |
| PARN | Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease) | 5 | UniProt NCBI |
| GALC | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | 5 | UniProt NCBI |
| TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | 5 | UniProt NCBI |
| BYSL | Bystin | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8953854 | 0.00371793814615 | 0.8 | BYSL TRMT112 TRMT11 PARN | Metabolism of RNA |
| REAC:R-HSA-6782315 | 0.0100756681589 | 0.4 | TRMT11 TRMT112 | tRNA modification in the nucleus and cytosol |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BYSL | PARN | 0.999 | 0.148 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| TRMT112 | TRMT11 | 0.998 | 0.05 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM |
| GALC | TRMT11 | 0.99 | 0.04 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BYSL | TRMT112 | 0.97 | 0.212 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| GALC | TRMT112 | 0.447 | 0.034 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| GALC | BYSL | 0.043 | 0.04 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| GALC | PARN | 0.018 | 0.056 | bioplex3_WMM WMM_only | |
| PARN | TRMT112 | 0.015 | 0.158 | bioplex3_WMM WMM_only |
Related Complexes