hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11030.1
Complex Portal: CPX-14807
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GPBP1 | Vasculin (GC-rich promoter-binding protein 1) (Vascular wall-linked protein) | 5 | UniProt NCBI |
| GRPEL1 | GrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1) | 5 | UniProt NCBI |
| DENND2D | DENN domain-containing protein 2D | 3 | UniProt NCBI |
| HSPA9 | Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74) | 5 | UniProt NCBI |
| PALLD | Palladin (SIH002) (Sarcoma antigen NY-SAR-77) | 5 | UniProt NCBI |
| RTF1 | RNA polymerase-associated protein RTF1 homolog | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7124 | 1.70876175213e-05 | 0.333333333333 | GRPEL1 HSPA9 | HSPA9-GRPEL1 complex |
| CORUM:7122 | 5.12534978153e-05 | 0.333333333333 | GRPEL1 HSPA9 | HSPA9-GRPEL1-GRPEL2 complex |
| CORUM:7126 | 0.000102488289015 | 0.333333333333 | GRPEL1 HSPA9 | HSPA9-GRPEL1-GRPEL2-TIMM44 complex |
| HPA:0550053 | 0.0401973652514 | 0.833333333333 | GRPEL1 RTF1 HSPA9 GPBP1 DENND2D | stomach 2; glandular cells[High] |
| HPA:0130053 | 0.0402861370309 | 0.833333333333 | GRPEL1 RTF1 HSPA9 GPBP1 DENND2D | colon; glandular cells[High] |
| HPA:0540053 | 0.0412728490261 | 0.833333333333 | GRPEL1 RTF1 HSPA9 GPBP1 DENND2D | stomach 1; glandular cells[High] |
| REAC:R-HSA-1268020 | 0.0452196184553 | 0.333333333333 | GRPEL1 HSPA9 | Mitochondrial protein import |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GRPEL1 | HSPA9 | 0.998 | 0.732 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM bioplex3_HCT116 fraction boldt_WMM | |
| GPBP1 | DENND2D | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DENND2D | HSPA9 | 0.984 | 0.18 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| GRPEL1 | PALLD | 0.979 | 0.086 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| GRPEL1 | DENND2D | 0.974 | 0.078 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RTF1 | DENND2D | 0.972 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RTF1 | GPBP1 | 0.213 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only | |
| GPBP1 | HSPA9 | 0.163 | 0.164 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PALLD | HSPA9 | 0.12 | 0.188 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM fraction | |
| RTF1 | HSPA9 | 0.104 | 0.126 | bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM | |
| GRPEL1 | RTF1 | 0.062 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| GRPEL1 | GPBP1 | 0.043 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| PALLD | RTF1 | 0.021 | 0.026 | bioplex3_WMM youn_WMM WMM_only | |
| PALLD | DENND2D | 0.021 | 0.064 | bioplex3_HCT116 WMM_only | |
| PALLD | GPBP1 | 0.006 | 0.118 | youn_WMM gupta_WMM WMM_only |
Related Complexes