hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11032.1
Complex Portal: CPX-15658
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| APOBEC3B | DNA dC->dU-editing enzyme APOBEC-3B (A3B) (EC 3.5.4.38) (Phorbolin-1-related protein) (Phorbolin-2/3) | 5 | UniProt NCBI |
| ELAVL2 | ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1) | 4 | UniProt NCBI |
| CASC3 | Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz) | 5 | UniProt NCBI |
| PABPC4L | Polyadenylate-binding protein 4-like (PABP-4-like) (Poly(A)-binding protein 4-like) | 3 | UniProt NCBI |
| PUM2 | Pumilio homolog 2 (Pumilio-2) | 5 | UniProt NCBI |
| PAIP2 | Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2) (PAIP-2) (Poly(A)-binding protein-interacting protein 2) | 5 | UniProt NCBI |
| PAIP2B | Polyadenylate-binding protein-interacting protein 2B (PABP-interacting protein 2B) (PAIP-2B) (Poly(A)-binding protein-interacting protein 2B) | 4 | UniProt NCBI |
| ELAVL3 | ELAV-like protein 3 (Hu-antigen C) (HuC) (Paraneoplastic cerebellar degeneration-associated antigen) (Paraneoplastic limbic encephalitis antigen 21) | 4 | UniProt NCBI |
| RBM45 | RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003730 | 0.00656544696377 | 0.444444444444 | ELAVL3 ELAVL2 PUM2 PABPC4L | mRNA 3'-UTR binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ELAVL2 | ELAVL3 | 0.999 | 0.11 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PUM2 | ELAVL2 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | ||
| PAIP2B | CASC3 | 0.994 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| PAIP2B | PAIP2 | 0.992 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| ELAVL2 | PAIP2 | 0.988 | 0.056 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| PUM2 | PAIP2 | 0.986 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| ELAVL2 | CASC3 | 0.982 | 0.146 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ELAVL2 | PAIP2B | 0.975 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| ELAVL2 | APOBEC3B | 0.969 | 0.044 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PUM2 | PAIP2B | 0.96 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| ELAVL2 | RBM45 | 0.959 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM treiber_WMM | ||
| PAIP2 | CASC3 | 0.948 | 0.116 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RBM45 | CASC3 | 0.872 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PUM2 | APOBEC3B | 0.773 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | ||
| APOBEC3B | CASC3 | 0.756 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| RBM45 | APOBEC3B | 0.731 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PUM2 | RBM45 | 0.627 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RBM45 | PAIP2B | 0.587 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PUM2 | ELAVL3 | 0.53 | bioplex_WMM bioplex3_WMM WMM_only | ||
| APOBEC3B | PAIP2 | 0.511 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only | |
| APOBEC3B | PAIP2B | 0.472 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELAVL3 | PAIP2 | 0.47 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only | |
| RBM45 | PAIP2 | 0.47 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELAVL3 | APOBEC3B | 0.303 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only | |
| PUM2 | CASC3 | 0.296 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| ELAVL3 | RBM45 | 0.283 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELAVL3 | PAIP2B | 0.191 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ELAVL3 | CASC3 | 0.162 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes