hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11059.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLIT1 | Slit homolog 1 protein (Slit-1) (Multiple epidermal growth factor-like domains protein 4) (Multiple EGF-like domains protein 4) | 5 | UniProt NCBI |
| RFNG | Beta-1,3-N-acetylglucosaminyltransferase radical fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) | 4 | UniProt NCBI |
| GALNT3 | Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (Polypeptide GalNAc transferase 3) (GalNAc-T3) (pp-GaNTase 3) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) | 5 | UniProt NCBI |
| CD209 | CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209) | 5 | UniProt NCBI |
| ELOVL1 | Very long chain fatty acid elongase 1 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL1) (ELOVL fatty acid elongase 1) (ELOVL FA elongase 1) (Elongation of very long chain fatty acids protein 1) (Very long chain 3-ketoacyl-CoA synthase 1) (Very long chain 3-oxoacyl-CoA synthase 1) | 5 | UniProt NCBI |
| HTR1B | 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (S12) (Serotonin 1D beta receptor) (5-HT-1D-beta) (Serotonin receptor 1B) | 5 | UniProt NCBI |
| SYNE2 | Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2) | 5 | UniProt NCBI |
| SLC1A4 | Neutral amino acid transporter A (Alanine/serine/cysteine/threonine transporter 1) (ASCT-1) (Solute carrier family 1 member 4) | 5 | UniProt NCBI |
| TMCC3 | Transmembrane and coiled-coil domain protein 3 | 4 | UniProt NCBI |
| NAPEPLD | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) | 5 | UniProt NCBI |
| CLEC4M | C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03264 | 6.36294344425e-05 | 0.2 | CD209 CLEC4M | Virion - Flavivirus |
| KEGG:03260 | 0.000127212422719 | 0.2 | CD209 CLEC4M | Virion - Human immunodeficiency virus |
| KEGG:00514 | 0.0163216862479 | 0.2 | RFNG GALNT3 | Other types of O-glycan biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CD209 | CLEC4M | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| HTR1B | CD209 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLIT1 | HTR1B | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RFNG | HTR1B | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GALNT3 | HTR1B | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TMCC3 | HTR1B | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ELOVL1 | HTR1B | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CD209 | NAPEPLD | 0.985 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SYNE2 | HTR1B | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NAPEPLD | CLEC4M | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SLC1A4 | HTR1B | 0.965 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| HTR1B | CLEC4M | 0.961 | bioplex_WMM bioplex3_WMM WMM_only | |
| TMCC3 | SLIT1 | 0.904 | 0.036 | bioplex3_WMM WMM_only |
| RFNG | SLIT1 | 0.902 | bioplex3_WMM WMM_only | |
| GALNT3 | SLIT1 | 0.902 | 0.246 | bioplex3_WMM WMM_only |
| HTR1B | NAPEPLD | 0.902 | bioplex3_WMM WMM_only | |
| SYNE2 | SLIT1 | 0.892 | 0.11 | bioplex3_WMM WMM_only |
| RFNG | GALNT3 | 0.796 | bioplex3_WMM WMM_only | |
| SLIT1 | ELOVL1 | 0.703 | 0.118 | bioplex3_WMM WMM_only |
| RFNG | SYNE2 | 0.675 | bioplex3_WMM WMM_only | |
| RFNG | TMCC3 | 0.675 | bioplex3_WMM WMM_only | |
| SLC1A4 | SLIT1 | 0.663 | 0.078 | bioplex3_WMM WMM_only |
| SLC1A4 | ELOVL1 | 0.509 | 0.016 | bioplex3_WMM WMM_only |
| RFNG | SLC1A4 | 0.44 | bioplex3_WMM WMM_only | |
| SYNE2 | GALNT3 | 0.356 | 0.138 | bioplex3_WMM WMM_only |
| GALNT3 | TMCC3 | 0.356 | 0.082 | bioplex3_WMM WMM_only |
| RFNG | ELOVL1 | 0.343 | bioplex3_WMM WMM_only | |
| TMCC3 | ELOVL1 | 0.334 | 0.034 | bioplex3_WMM WMM_only |
| SYNE2 | ELOVL1 | 0.315 | 0.04 | bioplex3_WMM WMM_only |
| SYNE2 | TMCC3 | 0.304 | 0.152 | bioplex3_WMM youn_WMM WMM_only |
| GALNT3 | SLC1A4 | 0.254 | 0.086 | bioplex3_WMM WMM_only |
| GALNT3 | ELOVL1 | 0.22 | 0.024 | bioplex3_WMM WMM_only |
| TMCC3 | SLC1A4 | 0.112 | 0.036 | bioplex3_WMM WMM_only |
| SYNE2 | SLC1A4 | 0.112 | 0.188 | bioplex3_WMM WMM_only |
Related Complexes