hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11066.1
Complex Portal: CPX-21209
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLHL17 | Kelch-like protein 17 (Actinfilin) | 5 | UniProt NCBI |
| KLHL3 | Kelch-like protein 3 | 5 | UniProt NCBI |
| ARMC10 | Armadillo repeat-containing protein 10 (Splicing variant involved in hepatocarcinogenesis protein) | 5 | UniProt NCBI |
| KLHL12 | Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6266 | 0.049938562206 | 0.25 | KLHL3 | Ubiquitin E3 ligase (CUL3, KLHL3, WNK4) |
| CORUM:6267 | 0.049938562206 | 0.25 | KLHL3 | Ubiquitin E3 ligase (CUL3, KLHL3) |
| CORUM:6815 | 0.049938562206 | 0.25 | KLHL12 | DRD4-KLHL12-CUL3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KLHL17 | KLHL3 | 0.996 |
mutually_exclusive (O95198)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KLHL3 | ARMC10 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KLHL12 | KLHL3 | 0.981 |
mutually_exclusive (O95198)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KLHL17 | ARMC10 | 0.468 | bioplex3_WMM WMM_only | ||
| KLHL12 | KLHL17 | 0.142 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KLHL12 | ARMC10 | 0.064 | 0.072 | bioplex3_WMM WMM_only |
Related Complexes