hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11068.1
Complex Portal: CPX-15234
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIVA1 | Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP) | 5 | UniProt NCBI |
| PCLAF | PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor) | 5 | UniProt NCBI |
| FANCM | Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog) | 5 | UniProt NCBI |
| PCNA | Proliferating cell nuclear antigen (PCNA) (Cyclin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1039 | 0.0249718442456 | 0.333333333333 | PCLAF | PCNA-PAF complex |
| CORUM:1040 | 0.0499402709677 | 0.333333333333 | PCLAF | p33ING1b-PCNA complex |
| CORUM:6795 | 0.0499402709677 | 0.333333333333 | SIVA1 | LPAR2-SIVA1 complex |
| CORUM:6796 | 0.0499402709677 | 0.333333333333 | SIVA1 | SIVA1-S1PR4 complex |
| CORUM:6797 | 0.0499402709677 | 0.333333333333 | SIVA1 | LPAR2-SIVA1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PCNA | PCLAF | 0.993 | 0.106 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| PCNA | FANCM | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SIVA1 | PCNA | 0.987 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| PCLAF | FANCM | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SIVA1 | PCLAF | 0.832 |
mutually_exclusive (P12004)
|
hein_WMM bioplex3_WMM WMM_only |
Related Complexes