hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11076.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
CORO1A	Coronin-1A (Coronin-like protein A) (Clipin-A) (Coronin-like protein p57) (Tryptophan aspartate-containing coat protein) (TACO)	5	UniProt NCBI
WDR1	WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)	5	UniProt NCBI
CFL1	Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)	5	UniProt NCBI
CORO1B	Coronin-1B (Coronin-2)	5	UniProt NCBI
CORO6	Coronin-6 (Coronin-like protein E) (Clipin-E)	4	UniProt NCBI
AFAP1	Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)	5	UniProt NCBI
SYNPO	Synaptopodin	5	UniProt NCBI
DSTN	Destrin (Actin-depolymerizing factor) (ADF)	5	UniProt NCBI
CFL2	Cofilin-2 (Cofilin, muscle isoform)	5	UniProt NCBI
CORO1C	Coronin-1C (Coronin-3) (hCRNN4)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0003779	1.32004918684e-10	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	actin binding
GO:0051015	5.97205035095e-10	0.8	WDR1 CORO1C CORO1B CFL1 DSTN CORO6 CFL2 CORO1A	actin filament binding
GO:0007015	8.12575671644e-10	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	actin filament organization
GO:0015629	2.19638778689e-09	0.9	WDR1 SYNPO CORO1B DSTN AFAP1 CFL1 CFL2 CORO1A CORO1C	actin cytoskeleton
GO:0030036	4.99920109885e-08	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	actin cytoskeleton organization
GO:0030029	1.33450530331e-07	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	actin filament-based process
GO:0097435	1.62343621351e-07	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	supramolecular fiber organization
GO:0008092	6.86895064999e-07	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	cytoskeletal protein binding
GO:0030043	1.15344049292e-05	0.3	CFL2 CFL1 DSTN	actin filament fragmentation
GO:0007010	3.56434715953e-05	0.9	WDR1 SYNPO CORO1B DSTN CFL1 CORO6 CFL2 CORO1A CORO1C	cytoskeleton organization
GO:0030042	0.000361003342891	0.4	WDR1 CFL2 CFL1 DSTN	actin filament depolymerization
GO:0005856	0.000650754322627	0.9	WDR1 SYNPO CORO1B DSTN AFAP1 CFL1 CFL2 CORO1A CORO1C	cytoskeleton
GO:0044877	0.00293647708351	0.8	WDR1 CORO1C CORO1B CFL1 DSTN CORO6 CFL2 CORO1A	protein-containing complex binding
GO:0110053	0.00321315142279	0.5	WDR1 CFL2 SYNPO CORO1A CORO1B	regulation of actin filament organization
GO:0051014	0.00642915610421	0.3	CFL2 CFL1 DSTN	actin filament severing
GO:0051261	0.00941974755121	0.4	WDR1 CFL2 CFL1 DSTN	protein depolymerization
GO:0032956	0.0114022498138	0.5	WDR1 CFL2 SYNPO CORO1A CORO1B	regulation of actin cytoskeleton organization
GO:0032970	0.0197078650144	0.5	WDR1 CFL2 SYNPO CORO1A CORO1B	regulation of actin filament-based process
WP:WP524	0.0216520902792	0.2	CFL1 CFL2	G13 signaling pathway
GO:1902903	0.0237835996432	0.5	WDR1 CFL2 SYNPO CORO1A CORO1B	regulation of supramolecular fiber organization
KEGG:05133	0.0355555587532	0.2	CFL1 CFL2	Pertussis
GO:0008154	0.0436892060701	0.4	WDR1 CFL2 CFL1 DSTN	actin polymerization or depolymerization

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
CORO1B	CORO1A	0.999	0.104	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM
CORO6	CORO1A	0.999	0.12	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
CORO1B	CORO1C	0.999	0.188	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM
CFL2	CFL1	0.999	0.918	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only
CFL2	CORO1C	0.999	0.178	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
CORO6	CORO1C	0.999	0.084	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
CORO1A	CORO1C	0.998	0.08	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
CORO6	CORO1B	0.998	0.148	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
DSTN	AFAP1	0.993		hein_WMM bioplex_WMM bioplex3_WMM WMM_only
WDR1	CORO1C	0.991	0.362	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 fraction treiber_WMM
CFL1	DSTN	0.983	0.572	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM
DSTN	CORO1C	0.981	0.304	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
CFL2	DSTN	0.979	0.476	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only
CFL1	CORO1C	0.965	0.184	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM
SYNPO	CORO1C	0.963		hein_WMM hein ()
CORO1C	AFAP1	0.963		hein_WMM hein ()
CFL1	AFAP1	0.952		hein_WMM bioplex_WMM bioplex3_WMM WMM_only
WDR1	CFL2	0.95	0.298	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM fraction
CORO1B	CFL2	0.938	0.17	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
WDR1	CFL1	0.925	0.518	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
CORO1B	WDR1	0.908	0.266	hein_WMM bioplex_WMM bioplex3_WMM fraction treiber_WMM
WDR1	DSTN	0.901	0.474	hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction
SYNPO	DSTN	0.781		hein_WMM WMM_only
CFL2	AFAP1	0.773		hein_WMM WMM_only
CORO1B	SYNPO	0.773		hein_WMM WMM_only
WDR1	AFAP1	0.773		hein_WMM WMM_only
SYNPO	AFAP1	0.773		hein_WMM WMM_only
CORO1B	AFAP1	0.773		hein_WMM WMM_only
SYNPO	WDR1	0.764		hein_WMM WMM_only
SYNPO	CFL1	0.764		hein_WMM WMM_only
CORO1B	DSTN	0.758	0.19	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only
CORO1B	CFL1	0.74	0.146	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
SYNPO	CFL2	0.351		hein_WMM WMM_only
CORO1A	DSTN	0.065	0.07	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
CORO6	DSTN	0.062	0.058	bioplex3_WMM bioplex3_HCT116 WMM_only
CORO1A	CFL2	0.019	0.104	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
CORO6	CFL2	0.019	0.12	bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only
CORO6	CFL1	0.006	0.2	bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only
CORO1A	WDR1	0.005	0.41	bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction treiber_WMM
CORO1A	CFL1	0.003	0.396	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
CORO6	WDR1	0.002	0.146	bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only

Related Complexes

Genename	Complexes
CORO1A	huMAP3_01075.1 huMAP3_04263.1 huMAP3_04826.1 huMAP3_05614.1 huMAP3_07117.1 huMAP3_07351.1 huMAP3_07776.1 huMAP3_09579.1 huMAP3_09596.1 huMAP3_09808.1 huMAP3_10784.1 huMAP3_11076.1
WDR1	huMAP3_02272.1 huMAP3_06026.1 huMAP3_09165.1 huMAP3_09870.1 huMAP3_11076.1
CFL1	huMAP3_03395.1 huMAP3_03694.1 huMAP3_05614.1 huMAP3_06125.1 huMAP3_07776.1 huMAP3_09579.1 huMAP3_11076.1 huMAP3_14124.1
CORO1B	huMAP3_01075.1 huMAP3_02173.1 huMAP3_03762.1 huMAP3_04263.1 huMAP3_04826.1 huMAP3_05614.1 huMAP3_06395.1 huMAP3_07117.1 huMAP3_07351.1 huMAP3_07776.1 huMAP3_08255.1 huMAP3_09579.1 huMAP3_09596.1 huMAP3_09808.1 huMAP3_10673.1 huMAP3_10784.1 huMAP3_11076.1
CORO6	huMAP3_00275.1 huMAP3_02173.1 huMAP3_05614.1 huMAP3_07351.1 huMAP3_08255.1 huMAP3_08902.1 huMAP3_09579.1 huMAP3_09596.1 huMAP3_09808.1 huMAP3_10784.1 huMAP3_11076.1 huMAP3_13337.1 huMAP3_13832.1 huMAP3_14117.1 huMAP3_14321.1 huMAP3_15320.1
AFAP1	huMAP3_03694.1 huMAP3_05614.1 huMAP3_07776.1 huMAP3_09121.1 huMAP3_09579.1 huMAP3_11076.1
SYNPO	huMAP3_01606.1 huMAP3_03689.1 huMAP3_04826.1 huMAP3_05057.1 huMAP3_05614.1 huMAP3_06017.1 huMAP3_07776.1 huMAP3_09555.1 huMAP3_09579.1 huMAP3_10270.1 huMAP3_10784.1 huMAP3_11076.1 huMAP3_12531.1 huMAP3_15295.1
DSTN	huMAP3_03395.1 huMAP3_03694.1 huMAP3_05614.1 huMAP3_06125.1 huMAP3_07776.1 huMAP3_09555.1 huMAP3_09579.1 huMAP3_11076.1
CFL2	huMAP3_02272.1 huMAP3_03395.1 huMAP3_06026.1 huMAP3_09068.1 huMAP3_09579.1 huMAP3_11076.1
CORO1C	huMAP3_03689.1 huMAP3_04826.1 huMAP3_05614.1 huMAP3_07776.1 huMAP3_09555.1 huMAP3_09579.1 huMAP3_10784.1 huMAP3_11076.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11076.1