hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11107.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CUL7 | Cullin-7 (CUL-7) | 5 | UniProt NCBI |
| ZNF761 | Zinc finger protein 761 | 3 | UniProt NCBI |
| MRI1 | Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) | 5 | UniProt NCBI |
| UBE2F | NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F) | 5 | UniProt NCBI |
| ZSWIM6 | Zinc finger SWIM domain-containing protein 6 | 3 | UniProt NCBI |
| ZNF616 | Zinc finger protein 616 | 3 | UniProt NCBI |
| ZNF841 | Zinc finger protein 841 | 3 | UniProt NCBI |
| TP53 | Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53) | 5 | UniProt NCBI |
| GLMN | Glomulin (FK506-binding protein-associated protein) (FAP) (FKBP-associated protein) | 5 | UniProt NCBI |
| CUL9 | Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6577 | 5.88502576438e-07 | 0.3 | CUL7 CUL9 TP53 | 3M complex |
| KEGG:05168 | 0.00366907782272 | 0.4 | ZNF761 TP53 ZNF616 ZNF841 | Herpes simplex virus 1 infection |
| HP:0002690 | 0.0374294407319 | 0.2 | TP53 ZSWIM6 | Large sella turcica |
| HP:0007376 | 0.0493214801054 | 0.2 | TP53 ZSWIM6 | Abnormal choroid plexus morphology |
| CORUM:2681 | 0.0499436884912 | 0.1 | TP53 | p53 homotetramer complex |
| CORUM:5811 | 0.0499436884912 | 0.1 | TP53 | p53-BCL2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CUL7 | CUL9 | 0.999 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GLMN | CUL7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TP53 | CUL9 | 0.997 | 0.658421901077 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| GLMN | CUL9 | 0.997 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| CUL7 | TP53 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CUL9 | ZNF761 | 0.995 | 0.088 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| CUL9 | ZNF616 | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ZNF841 | CUL9 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| UBE2F | CUL9 | 0.98 | 0.066 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| MRI1 | CUL9 | 0.965 | 0.1 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| GLMN | ZSWIM6 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNF616 | ZNF761 | 0.795 | bioplex3_WMM WMM_only | |
| TP53 | ZNF761 | 0.532 | 0.51651255989 | bioplex_WMM bioplex3_WMM WMM_only |
| CUL7 | ZNF761 | 0.436 | bioplex3_WMM WMM_only | |
| ZNF841 | ZNF761 | 0.415 | bioplex3_WMM WMM_only | |
| UBE2F | ZNF761 | 0.415 | 0.114 | bioplex3_WMM WMM_only |
| UBE2F | ZNF841 | 0.415 | bioplex3_WMM WMM_only | |
| CUL7 | ZNF616 | 0.335 | bioplex3_WMM WMM_only | |
| ZSWIM6 | CUL9 | 0.333 | bioplex_WMM bioplex3_WMM WMM_only | |
| UBE2F | ZNF616 | 0.274 | bioplex3_WMM WMM_only | |
| ZNF841 | ZNF616 | 0.274 | bioplex3_WMM WMM_only | |
| MRI1 | ZNF761 | 0.257 | 0.028 | bioplex3_WMM WMM_only |
| MRI1 | ZNF616 | 0.24 | bioplex3_WMM WMM_only | |
| TP53 | ZNF616 | 0.223 | bioplex3_WMM WMM_only | |
| GLMN | ZNF761 | 0.217 | 0.08 | bioplex3_WMM WMM_only |
| GLMN | ZNF616 | 0.192 | bioplex3_WMM WMM_only | |
| CUL7 | MRI1 | 0.168 | bioplex3_WMM WMM_only | |
| ZSWIM6 | CUL7 | 0.164 | bioplex_WMM bioplex3_WMM WMM_only | |
| GLMN | ZNF841 | 0.089 | bioplex3_WMM WMM_only | |
| GLMN | UBE2F | 0.089 | 0.052 | bioplex3_WMM WMM_only |
| CUL7 | ZNF841 | 0.078 | bioplex3_WMM WMM_only | |
| CUL7 | UBE2F | 0.078 | bioplex3_WMM WMM_only | |
| UBE2F | TP53 | 0.076 | 0.57310232303 | bioplex3_WMM WMM_only |
| ZNF841 | TP53 | 0.076 | bioplex3_WMM WMM_only | |
| MRI1 | ZNF841 | 0.03 | bioplex3_WMM WMM_only | |
| MRI1 | UBE2F | 0.03 | 0.052 | bioplex3_WMM WMM_only |
| GLMN | TP53 | 0.027 | 0.458378202386 | bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| GLMN | MRI1 | 0.019 | 0.078 | bioplex3_WMM youn_WMM WMM_only |
| MRI1 | TP53 | 0.007 | 0.600598238132 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes