hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11109.1

Complex Portal: CPX-22731

Confidence: Medium High

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Genename	Protein Name	Uniprot Annotation Score	Links
KPNA5	Importin subunit alpha-6 (Karyopherin subunit alpha-5)	5	UniProt NCBI
NUP50	Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)	5	UniProt NCBI
SFT2D2	Vesicle transport protein SFT2B (SFT2 domain-containing protein 2)	5	UniProt NCBI
SPOP	Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)	5	UniProt NCBI
SPOPL	Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2)	5	UniProt NCBI
WDHD1	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1)	5	UniProt NCBI
XCL1	Lymphotactin (ATAC) (C motif chemokine 1) (Cytokine SCM-1) (Lymphotaxin) (SCM-1-alpha) (Small-inducible cytokine C1) (XC chemokine ligand 1)	5	UniProt NCBI

Showing 1 to 7 of 7 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04340	0.0100614067411	0.285714285714	SPOP SPOPL	Hedgehog signaling pathway
WP:WP4249	0.0117684016707	0.285714285714	SPOP SPOPL	Hedgehog signaling pathway
REAC:R-HSA-168276	0.0251789059	0.285714285714	NUP50 KPNA5	NS1 Mediated Effects on Host Pathways

Showing 1 to 3 of 3 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
NUP50	KPNA5	0.998	0.166	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
SPOPL	SPOP	0.998			bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only
SPOP	NUP50	0.997	0.154		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM
SPOPL	KPNA5	0.996		structurally_consistent (dimer)	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
SPOP	KPNA5	0.994	0.066	structurally_consistent (dimer)	bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only
XCL1	SPOPL	0.989			bioplex3_HEK293 bioplex3_WMM WMM_only
SFT2D2	SPOPL	0.989			bioplex3_HEK293 bioplex3_WMM WMM_only
SPOPL	NUP50	0.979		mutually_exclusive (O15131)	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
NUP50	WDHD1	0.963	0.134		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction
SFT2D2	XCL1	0.415			bioplex3_WMM WMM_only

Showing 1 to 10 of 19 entries

Related Complexes

Genename	Complexes
WDHD1	huMAP3_05366.1 huMAP3_06231.1 huMAP3_07428.1 huMAP3_08240.1 huMAP3_08335.1 huMAP3_11109.1
SFT2D2	huMAP3_00700.1 huMAP3_04482.1 huMAP3_05622.1 huMAP3_08079.1 huMAP3_09322.1 huMAP3_11109.1 huMAP3_11771.1 huMAP3_14258.1
SPOP	huMAP3_04845.1 huMAP3_05366.1 huMAP3_05622.1 huMAP3_06407.1 huMAP3_07855.1 huMAP3_08079.1 huMAP3_08567.1 huMAP3_09322.1 huMAP3_11109.1 huMAP3_11284.1 huMAP3_13697.1 huMAP3_15080.1
XCL1	huMAP3_00700.1 huMAP3_04482.1 huMAP3_05622.1 huMAP3_08079.1 huMAP3_09322.1 huMAP3_11109.1 huMAP3_11284.1 huMAP3_11771.1 huMAP3_14258.1
NUP50	huMAP3_04845.1 huMAP3_05366.1 huMAP3_06407.1 huMAP3_07428.1 huMAP3_07479.1 huMAP3_07855.1 huMAP3_08240.1 huMAP3_09694.1 huMAP3_10000.1 huMAP3_11109.1 huMAP3_12581.1
KPNA5	huMAP3_05366.1 huMAP3_05622.1 huMAP3_06407.1 huMAP3_07855.1 huMAP3_08079.1 huMAP3_09694.1 huMAP3_10000.1 huMAP3_11109.1 huMAP3_11284.1
SPOPL	huMAP3_00700.1 huMAP3_04482.1 huMAP3_05622.1 huMAP3_06407.1 huMAP3_08079.1 huMAP3_09322.1 huMAP3_11109.1 huMAP3_11284.1 huMAP3_11771.1 huMAP3_14258.1