hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11110.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AGPS | Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase) | 5 | UniProt NCBI |
| PEX7 | Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) | 5 | UniProt NCBI |
| PEX13 | Peroxisomal membrane protein PEX13 (Peroxin-13) | 5 | UniProt NCBI |
| C6orf226 | Uncharacterized protein C6orf226 | 2 | UniProt NCBI |
| ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04146 | 8.08907328692e-08 | 0.8 | ACAA1 AGPS PEX13 PEX7 | Peroxisome |
| REAC:R-HSA-9033241 | 8.29152132817e-08 | 0.8 | ACAA1 AGPS PEX13 PEX7 | Peroxisomal protein import |
| REAC:R-HSA-9609507 | 5.78164213131e-06 | 0.8 | ACAA1 AGPS PEX13 PEX7 | Protein localization |
| HP:0010655 | 6.51146833402e-05 | 0.6 | AGPS PEX13 PEX7 | Epiphyseal stippling |
| REAC:R-HSA-9033500 | 0.000227895019208 | 0.4 | AGPS ACAA1 | TYSND1 cleaves peroxisomal proteins |
| HP:0010656 | 0.000471067856483 | 0.6 | AGPS PEX13 PEX7 | Abnormal epiphyseal ossification |
| GO:0005777 | 0.000649914918254 | 0.8 | ACAA1 AGPS PEX13 PEX7 | peroxisome |
| GO:0042579 | 0.000649914918254 | 0.8 | ACAA1 AGPS PEX13 PEX7 | microbody |
| WP:WP5275 | 0.000798299856649 | 0.4 | AGPS PEX7 | Ether lipid biosynthesis |
| HP:0003336 | 0.00321376516039 | 0.6 | AGPS PEX13 PEX7 | Abnormal enchondral ossification |
| HP:0010965 | 0.00582689447108 | 0.4 | PEX7 PEX13 | Abnormal circulating phytanic acid concentration |
| HP:0010571 | 0.00582689447108 | 0.4 | PEX7 PEX13 | Elevated circulating phytanic acid concentration |
| HP:0010964 | 0.00768171284681 | 0.4 | PEX7 PEX13 | Abnormal circulating long-chain fatty-acid concentration |
| GO:0031907 | 0.0094606249379 | 0.6 | AGPS ACAA1 PEX7 | microbody lumen |
| GO:0005782 | 0.0094606249379 | 0.6 | AGPS ACAA1 PEX7 | peroxisomal matrix |
| GO:0031903 | 0.0145266888919 | 0.6 | AGPS PEX13 PEX7 | microbody membrane |
| GO:0005778 | 0.0145266888919 | 0.6 | AGPS PEX13 PEX7 | peroxisomal membrane |
| HP:0010766 | 0.0149955818628 | 0.6 | AGPS PEX13 PEX7 | Ectopic calcification |
| HP:0005930 | 0.0264180981427 | 0.6 | AGPS PEX13 PEX7 | Abnormal epiphysis morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| C6orf226 | PEX7 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| C6orf226 | ACAA1 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PEX7 | PEX13 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAA1 | PEX7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| C6orf226 | AGPS | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| C6orf226 | PEX13 | 0.921 | bioplex_WMM bioplex3_WMM WMM_only | |
| AGPS | PEX7 | 0.53 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| AGPS | PEX13 | 0.151 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| AGPS | ACAA1 | 0.105 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only |
| ACAA1 | PEX13 | 0.027 | 0.11 | bioplex3_WMM WMM_only |
Related Complexes