hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11115.1

Confidence: Medium High

Genename	Protein Name	Uniprot Annotation Score	Links
EEFSEC	Selenocysteine-specific elongation factor (EC 3.6.5.-) (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific)	5	UniProt NCBI
MROH1	Maestro heat-like repeat-containing protein family member 1 (HEAT repeat-containing protein 7A)	3	UniProt NCBI
RPS27	Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1)	5	UniProt NCBI
RPS27L	Ribosomal protein eS27-like (40S ribosomal protein S27-like) (Small ribosomal subunit protein eS27-like)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-2408557	0.000169699262125	0.75	RPS27L EEFSEC RPS27	Selenocysteine synthesis
REAC:R-HSA-2408522	0.000309528132151	0.75	RPS27L EEFSEC RPS27	Selenoamino acid metabolism
REAC:R-HSA-9735869	0.0068064250699	0.5	RPS27 RPS27L	SARS-CoV-1 modulates host translation machinery
REAC:R-HSA-71291	0.007608748274	0.75	RPS27L EEFSEC RPS27	Metabolism of amino acids and derivatives
REAC:R-HSA-9754678	0.0130136556072	0.5	RPS27 RPS27L	SARS-CoV-2 modulates host translation machinery
REAC:R-HSA-72695	0.0135329645116	0.5	RPS27 RPS27L	Formation of the ternary complex, and subsequently, the 43S complex
REAC:R-HSA-72649	0.0174510452107	0.5	RPS27 RPS27L	Translation initiation complex formation
REAC:R-HSA-72702	0.0174510452107	0.5	RPS27 RPS27L	Ribosomal scanning and start codon recognition
REAC:R-HSA-72662	0.0180511544442	0.5	RPS27 RPS27L	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
KEGG:03010	0.0207865818092	0.5	RPS27 RPS27L	Ribosome
REAC:R-HSA-156902	0.0389395459224	0.5	RPS27 RPS27L	Peptide chain elongation
REAC:R-HSA-192823	0.0389395459224	0.5	RPS27 RPS27L	Viral mRNA Translation
REAC:R-HSA-72764	0.041644107744	0.5	RPS27 RPS27L	Eukaryotic Translation Termination
REAC:R-HSA-156842	0.0425656343513	0.5	RPS27 RPS27L	Eukaryotic Translation Elongation
REAC:R-HSA-9692914	0.0434971593242	0.5	RPS27 RPS27L	SARS-CoV-1-host interactions
REAC:R-HSA-975956	0.0444386798825	0.5	RPS27 RPS27L	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
KEGG:05171	0.049994875911	0.5	RPS27 RPS27L	Coronavirus disease - COVID-19

Protein 1	Protein 2	Score	ProteomeHD	Evidence
RPS27L	RPS27	0.997	0.748	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
RPS27	EEFSEC	0.981	0.284	hein_WMM bioplex3_HEK293 WMM_only
MROH1	RPS27	0.961	0.014	bioplex3_WMM bioplex3_HCT116 WMM_only
RPS27L	MROH1	0.103	0.02	bioplex3_WMM WMM_only
RPS27L	EEFSEC	0.067	0.08	hein_WMM bioplex3_HEK293 WMM_only

Related Complexes

Genename	Complexes
EEFSEC	huMAP3_05053.1 huMAP3_08023.1 huMAP3_08373.1 huMAP3_09056.1 huMAP3_11037.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
MROH1	huMAP3_01273.1 huMAP3_01409.1 huMAP3_01838.1 huMAP3_01853.1 huMAP3_02538.1 huMAP3_03685.1 huMAP3_04186.1 huMAP3_07251.1 huMAP3_10036.1 huMAP3_10570.1 huMAP3_11115.1
RPS27	huMAP3_01409.1 huMAP3_01838.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08023.1 huMAP3_08179.1 huMAP3_08373.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
RPS27L	huMAP3_01232.1 huMAP3_01409.1 huMAP3_01535.1 huMAP3_02562.1 huMAP3_06383.1 huMAP3_08023.1 huMAP3_09415.1 huMAP3_11037.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1