hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11122.1
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARSI | Arylsulfatase I (ASI) (EC 3.1.6.-) | 5 | UniProt NCBI |
| SUMF2 | Inactive C-alpha-formylglycine-generating enzyme 2 (Paralog of formylglycine-generating enzyme) (pFGE) (Sulfatase-modifying factor 2) | 5 | UniProt NCBI |
| ERP29 | Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31) | 5 | UniProt NCBI |
| ARSG | Arylsulfatase G (ASG) (EC 3.1.6.1) (N-sulfoglucosamine-3-sulfatase) (EC 3.1.6.15) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1663150 | 7.69893532894e-08 | 1.0 | ARSG ARSI SUMF2 | The activation of arylsulfatases |
| REAC:R-HSA-163841 | 3.62549863672e-06 | 1.0 | ARSG ARSI SUMF2 | Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation |
| REAC:R-HSA-1660662 | 4.26427696795e-06 | 1.0 | ARSG ARSI SUMF2 | Glycosphingolipid metabolism |
| REAC:R-HSA-428157 | 2.90207867708e-05 | 1.0 | ARSG ARSI SUMF2 | Sphingolipid metabolism |
| REAC:R-HSA-556833 | 0.0177385429708 | 1.0 | ARSG ARSI SUMF2 | Metabolism of lipids |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SUMF2 | ARSG | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ARSI | SUMF2 | 0.972 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ERP29 | ARSG | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ERP29 | ARSI | 0.091 | bioplex3_HEK293 bioplex () | |
| ERP29 | SUMF2 | 0.02 | 0.086 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
Related Complexes