hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11127.1
Complex Portal: CPX-18226
Confidence: Medium High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GJB3 | Gap junction beta-3 protein (Connexin-31) (Cx31) | 5 | UniProt NCBI |
| PRND | Prion-like protein doppel (PrPLP) (Prion protein 2) | 5 | UniProt NCBI |
| CALHM2 | Calcium homeostasis modulator protein 2 (Protein FAM26B) | 3 | UniProt NCBI |
| GJB5 | Gap junction beta-5 protein (Connexin-31.1) (Cx31.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-190861 | 0.00386628370571 | 0.5 | GJB5 GJB3 | Gap junction assembly |
| REAC:R-HSA-190828 | 0.007571530532 | 0.5 | GJB5 GJB3 | Gap junction trafficking |
| REAC:R-HSA-157858 | 0.0079693038543 | 0.5 | GJB5 GJB3 | Gap junction trafficking and regulation |
| WP:WP536 | 0.015715675352 | 0.5 | GJB5 GJB3 | Calcium regulation in cardiac cells |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GJB3 | PRND | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GJB3 | GJB5 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PRND | CALHM2 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GJB3 | CALHM2 | 0.396 | bioplex3_WMM WMM_only |
Related Complexes