List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11136.1

Confidence: Medium High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
PRDM10	PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin)	5	UniProt   NCBI
FGF2	Fibroblast growth factor 2 (FGF-2) (Basic fibroblast growth factor) (bFGF) (Heparin-binding growth factor 2) (HBGF-2)	5	UniProt   NCBI
IL7R	Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CDw127) (CD antigen CD127)	5	UniProt   NCBI
TMEFF1	Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain)	5	UniProt   NCBI
HADHA	Trifunctional enzyme subunit alpha, mitochondrial (78 kDa gastrin-binding protein) (Monolysocardiolipin acyltransferase) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)]	5	UniProt   NCBI
DHRS2	Dehydrogenase/reductase SDR family member 2, mitochondrial (EC 1.1.1.-) (Dicarbonyl reductase HEP27) (Protein D) (Short chain dehydrogenase/reductase family 25C member 1) (Protein SDR25C1)	5	UniProt   NCBI
CD44	CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)	5	UniProt   NCBI
SDC2	Syndecan-2 (SYND2) (Fibroglycan) (Heparan sulfate proteoglycan core protein) (HSPG) (CD antigen CD362)	5	UniProt   NCBI
GPR50	Melatonin-related receptor (G protein-coupled receptor 50) (H9) [Cleaved into: C-terminal domain]	5	UniProt   NCBI
USF3	Basic helix-loop-helix domain-containing protein USF3 (Upstream transcription factor 3)	5	UniProt   NCBI
MTNAP1	Mitochondrial nucleoid-associated protein 1 (Cell migration-inducing gene 3 protein) (Human lung cancer oncogene 8 protein) (HLC-8) (Protein C17orf80)	5	UniProt   NCBI
GMEB2	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (DNA-binding protein p79PIF) (Parvovirus initiation factor p79) (PIF p79)	5	UniProt   NCBI
GMEB1	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (DNA-binding protein p96PIF) (Parvovirus initiation factor p96) (PIF p96)	5	UniProt   NCBI
HADHB	Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)]	5	UniProt   NCBI
SDC4	Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)	5	UniProt   NCBI
SDC1	Syndecan-1 (SYND1) (CD antigen CD138)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:7262	4.10333215354e-05	0.153846153846	HADHA HADHB	3-Hydroxyacyl CoA dehydrogenase
REAC:R-HSA-3000170	0.000229093302057	0.230769230769	FGF2 SDC4 SDC1	Syndecan interactions
REAC:R-HSA-77305	0.000598382447191	0.153846153846	HADHA HADHB	Beta oxidation of palmitoyl-CoA to myristoyl-CoA
REAC:R-HSA-77285	0.000598382447191	0.153846153846	HADHA HADHB	Beta oxidation of myristoyl-CoA to lauroyl-CoA
HP:0025145	0.000760826170135	0.153846153846	HADHA HADHB	Rigors
HP:0025144	0.000760826170135	0.153846153846	HADHA HADHB	Shivering
REAC:R-HSA-77350	0.00199260676058	0.153846153846	HADHA HADHB	Beta oxidation of hexanoyl-CoA to butanoyl-CoA
REAC:R-HSA-77310	0.00199260676058	0.153846153846	HADHA HADHB	Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
REAC:R-HSA-77348	0.00199260676058	0.153846153846	HADHA HADHB	Beta oxidation of octanoyl-CoA to hexanoyl-CoA
REAC:R-HSA-3000171	0.00253884618379	0.230769230769	FGF2 SDC4 SDC1	Non-integrin membrane-ECM interactions
REAC:R-HSA-77346	0.00298741024895	0.153846153846	HADHA HADHB	Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
REAC:R-HSA-1482798	0.00298741024895	0.153846153846	HADHA HADHB	Acyl chain remodeling of CL
REAC:R-HSA-77288	0.00298741024895	0.153846153846	HADHA HADHB	mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
HP:0006555	0.0045603764747	0.153846153846	HADHA HADHB	Diffuse hepatic steatosis
WP:WP3871	0.00560333986549	0.153846153846	HADHA HADHB	Valproic acid pathway
REAC:R-HSA-77286	0.00894425512963	0.153846153846	HADHA HADHB	mitochondrial fatty acid beta-oxidation of saturated fatty acids
KEGG:00062	0.0114058833075	0.153846153846	HADHA HADHB	Fatty acid elongation
WP:WP5123	0.0129505034666	0.153846153846	HADHA HADHB	Mitochondrial fatty acid oxidation disorders
HP:0008138	0.01593730064	0.153846153846	HADHA HADHB	Equinus calcaneus
REAC:R-HSA-3656253	0.0180509953769	0.153846153846	SDC1 SDC4	Defective EXT1 causes exostoses 1, TRPS2 and CHDS
REAC:R-HSA-3656237	0.0180509953769	0.153846153846	SDC1 SDC4	Defective EXT2 causes exostoses 2
REAC:R-HSA-9694614	0.0269367236592	0.153846153846	SDC1 SDC4	Attachment and Entry
HP:0003756	0.0272936739987	0.153846153846	HADHA HADHB	Skeletal myopathy
HP:0011808	0.0272936739987	0.153846153846	HADHA HADHB	Decreased patellar reflex
KEGG:05205	0.028350236648	0.230769230769	FGF2 SDC4 SDC1	Proteoglycans in cancer
REAC:R-HSA-3560783	0.0302886092005	0.153846153846	SDC1 SDC4	Defective B4GALT7 causes EDS, progeroid type
REAC:R-HSA-3560801	0.0302886092005	0.153846153846	SDC1 SDC4	Defective B3GAT3 causes JDSSDHD
REAC:R-HSA-4420332	0.0302886092005	0.153846153846	SDC1 SDC4	Defective B3GALT6 causes EDSP2 and SEMDJL1
KEGG:00071	0.031976259245	0.153846153846	HADHA HADHB	Fatty acid degradation
GO:0016507	0.0365196561665	0.153846153846	HADHA HADHB	mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0036125	0.0365196561665	0.153846153846	HADHA HADHB	fatty acid beta-oxidation multienzyme complex
WP:WP143	0.0391034347791	0.153846153846	HADHA HADHB	Fatty acid beta oxidation
HP:0009063	0.0416568309099	0.153846153846	HADHA HADHB	Progressive distal muscle weakness
KEGG:00280	0.0423024996272	0.153846153846	HADHA HADHB	Valine, leucine and isoleucine degradation
REAC:R-HSA-2024096	0.0456381529906	0.153846153846	SDC1 SDC4	HS-GAG degradation
HP:0008110	0.0499631138006	0.153846153846	HADHA HADHB	Equinovarus deformity
KEGG:01212	0.0499678013229	0.153846153846	HADHA HADHB	Fatty acid metabolism



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
GMEB2	GMEB1	1.0
HADHB	HADHA	1.0	0.968
SDC2	SDC4	0.999	0.108
SDC2	FGF2	0.999	0.126
SDC2	USF3	0.999
SDC2	GMEB1	0.999
SDC1	PRDM10	0.998	0.082
SDC4	HADHA	0.998	0.142
SDC2	HADHA	0.998	0.176
SDC2	PRDM10	0.998	0.146
SDC2	DHRS2	0.997	0.13
SDC2	GMEB2	0.997	0.102
SDC2	HADHB	0.997	0.144
SDC1	HADHA	0.996	0.118
SDC1	FGF2	0.994	0.098
SDC1	DHRS2	0.994	0.04
MTNAP1	HADHB	0.993	0.424
FGF2	GMEB2	0.992	0.104
FGF2	GMEB1	0.992
HADHA	CD44	0.991	0.268
FGF2	DHRS2	0.99	0.102
PRDM10	CD44	0.989	0.168
MTNAP1	HADHA	0.989	0.302
GMEB2	CD44	0.988	0.05
TMEFF1	HADHB	0.987
PRDM10	SDC4	0.987	0.042
SDC1	HADHB	0.986	0.082
FGF2	IL7R	0.985
SDC1	GMEB2	0.984	0.0844222222222
TMEFF1	DHRS2	0.983
GMEB2	DHRS2	0.982	0.046
GMEB1	DHRS2	0.982
GPR50	SDC2	0.98
TMEFF1	FGF2	0.98
HADHB	SDC4	0.98	0.054
FGF2	CD44	0.979	0.124
SDC2	SDC1	0.978	0.124
GMEB1	CD44	0.978
FGF2	PRDM10	0.976	0.076
GMEB2	SDC4	0.974	0.12
PRDM10	DHRS2	0.971	0.128
HADHB	CD44	0.969	0.336
MTNAP1	CD44	0.969	0.12
FGF2	SDC4	0.966	0.108
HADHB	FGF2	0.96	0.164
GMEB1	SDC4	0.951
SDC4	DHRS2	0.946	0.024
TMEFF1	PRDM10	0.946
TMEFF1	HADHA	0.928
FGF2	HADHA	0.926	0.122194029851
IL7R	GMEB1	0.92
DHRS2	CD44	0.918	0.064
SDC1	SDC4	0.907	0.204
HADHA	DHRS2	0.906	0.044
USF3	GMEB1	0.904
USF3	FGF2	0.902
USF3	GMEB2	0.902
MTNAP1	SDC4	0.899	0.066
IL7R	DHRS2	0.892
SDC4	CD44	0.889	0.096
IL7R	GMEB2	0.881
USF3	DHRS2	0.869
SDC1	GMEB1	0.847
HADHB	GMEB2	0.837	0.03
GMEB2	PRDM10	0.834	0.166
HADHB	DHRS2	0.791	0.056
MTNAP1	IL7R	0.718
USF3	SDC4	0.714
USF3	SDC1	0.688
IL7R	PRDM10	0.616
GMEB1	PRDM10	0.601
HADHB	PRDM10	0.53	0.174
HADHB	IL7R	0.411
USF3	HADHB	0.389
GMEB2	HADHA	0.363	0.072
TMEFF1	SDC4	0.357
USF3	PRDM10	0.356
HADHB	GMEB1	0.323
TMEFF1	SDC2	0.3
TMEFF1	SDC1	0.265
IL7R	HADHA	0.241
GMEB1	HADHA	0.223
MTNAP1	GMEB2	0.21	0.112
SDC1	CD44	0.176	0.094
USF3	HADHA	0.154
SDC1	MTNAP1	0.152	0.068
GPR50	GMEB1	0.148
PRDM10	HADHA	0.144	0.172
MTNAP1	DHRS2	0.143	0.054
MTNAP1	FGF2	0.128	0.074
GPR50	DHRS2	0.111
GPR50	GMEB2	0.1
MTNAP1	GMEB1	0.098
GPR50	SDC4	0.093
GPR50	FGF2	0.08
SDC2	CD44	0.061	0.092
SDC2	MTNAP1	0.059	0.082
TMEFF1	MTNAP1	0.055
MTNAP1	PRDM10	0.054	0.104
GPR50	HADHA	0.053
GPR50	USF3	0.042
GPR50	CD44	0.041
GPR50	MTNAP1	0.036
GPR50	HADHB	0.028
GPR50	SDC1	0.026
GPR50	PRDM10	0.013
TMEFF1	CD44	0.01





Related Complexes

Genename	Complexes
PRDM10	huMAP3_04564.1 huMAP3_06336.1 huMAP3_06654.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_13917.1
FGF2	huMAP3_04564.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1 huMAP3_14447.1
IL7R	huMAP3_04564.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1 huMAP3_14447.1
TMEFF1	huMAP3_01254.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_13917.1 huMAP3_14308.1
HADHA	huMAP3_06401.1 huMAP3_11136.1 huMAP3_13917.1
DHRS2	huMAP3_06598.1 huMAP3_06632.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1 huMAP3_14447.1
CD44	huMAP3_11136.1 huMAP3_13917.1 huMAP3_14777.1
SDC2	huMAP3_01430.1 huMAP3_05214.1 huMAP3_06598.1 huMAP3_08260.1 huMAP3_09364.1 huMAP3_11136.1 huMAP3_13917.1
GPR50	huMAP3_01430.1 huMAP3_02546.1 huMAP3_05214.1 huMAP3_06539.1 huMAP3_08260.1 huMAP3_09364.1 huMAP3_11136.1 huMAP3_11807.1 huMAP3_12321.1
USF3	huMAP3_01430.1 huMAP3_05214.1 huMAP3_06598.1 huMAP3_08260.1 huMAP3_09364.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13184.1 huMAP3_13783.1 huMAP3_13917.1 huMAP3_14447.1
MTNAP1	huMAP3_02845.1 huMAP3_03968.1 huMAP3_06401.1 huMAP3_08915.1 huMAP3_11136.1 huMAP3_13917.1
GMEB2	huMAP3_04564.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1 huMAP3_14447.1
GMEB1	huMAP3_04564.1 huMAP3_08736.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1 huMAP3_14447.1
HADHB	huMAP3_02845.1 huMAP3_06401.1 huMAP3_11136.1 huMAP3_13917.1 huMAP3_14011.1
SDC4	huMAP3_05136.1 huMAP3_09261.1 huMAP3_09364.1 huMAP3_10312.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1
SDC1	huMAP3_01947.1 huMAP3_06598.1 huMAP3_06813.1 huMAP3_08260.1 huMAP3_09364.1 huMAP3_11136.1 huMAP3_12824.1 huMAP3_13917.1