hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11190.1
Confidence: Medium  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
HPS1 | BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein) | 5 | UniProt   NCBI |
S100A6 | Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6) | 5 | UniProt   NCBI |
NEDD1 | Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) | 5 | UniProt   NCBI |
CDCA7L | Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2) | 5 | UniProt   NCBI |
DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt   NCBI |
TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) | 5 | UniProt   NCBI |
CTF1 | Cardiotrophin-1 (CT-1) | 5 | UniProt   NCBI |
ZNF821 | Zinc finger protein 821 | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:11 | 0.0499436884912 | 0.125 | HPS1 | BLOC-3 (biogenesis of lysosome-related organelles complex 3) |
  CORUM:241 | 0.0499436884912 | 0.125 | HPS1 | BLOC-3 (biogenesis of lysosome-related organelles complex 3) |
  CORUM:1982 | 0.0499436884912 | 0.125 | S100A6 | CACY homodimer complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TRADD |  NEDD1 | 0.983 | 0.024           | hein_WMM     bioplex3_WMM     hein ()     |
 NEDD1 |  HPS1 | 0.972 | 0.114           | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 TRADD |  S100A6 | 0.946 | 0.054           | hein_WMM     bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 ZNF821 |  S100A6 | 0.91 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 NEDD1 |  S100A6 | 0.881 | 0.06           | hein_WMM     bioplex3_HEK293     bioplex3_WMM     hein ()     |
 S100A6 |  CDCA7L | 0.851 | 0.07           | hein_WMM     bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 S100A6 |  CTF1 | 0.823 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 S100A6 |  DIAPH2 | 0.822 | 0.126           | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 ZNF821 |  CDCA7L | 0.415 |            | bioplex3_WMM     WMM_only     |
 ZNF821 |  DIAPH2 | 0.415 |            | bioplex3_WMM     WMM_only     |
 ZNF821 |  CTF1 | 0.278 |            | bioplex3_WMM     WMM_only     |
 TRADD |  ZNF821 | 0.278 |            | bioplex3_WMM     WMM_only     |
 DIAPH2 |  CDCA7L | 0.274 | 0.044           | bioplex3_WMM     WMM_only     |
 CTF1 |  CDCA7L | 0.25 |            | bioplex3_WMM     WMM_only     |
 TRADD |  CDCA7L | 0.25 | 0.058           | bioplex3_WMM     WMM_only     |
 TRADD |  DIAPH2 | 0.113 | 0.078           | bioplex3_WMM     WMM_only     |
 CTF1 |  DIAPH2 | 0.113 |            | bioplex3_WMM     WMM_only     |
 NEDD1 |  CDCA7L | 0.102 | 0.036           | bioplex3_WMM     WMM_only     |
 TRADD |  CTF1 | 0.095 |            | bioplex3_WMM     WMM_only     |
 NEDD1 |  CTF1 | 0.09 |            | bioplex3_WMM     WMM_only     |
 NEDD1 |  DIAPH2 | 0.034 | 0.08           | bioplex3_WMM     youn_WMM     WMM_only     |
 NEDD1 |  ZNF821 | 0.034 |            | bioplex3_WMM     youn_WMM     WMM_only     |
 S100A6 |  HPS1 | 0.005 | 0.08           | bioplex3_HCT116     WMM_only     |
Related Complexes