hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11190.1
Complex Portal: CPX-24152
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HPS1 | BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein) | 5 | UniProt NCBI |
| S100A6 | Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6) | 5 | UniProt NCBI |
| NEDD1 | Protein NEDD1 (Neural precursor cell expressed developmentally down-regulated protein 1) (NEDD-1) | 5 | UniProt NCBI |
| CDCA7L | Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2) | 5 | UniProt NCBI |
| DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt NCBI |
| TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain) | 5 | UniProt NCBI |
| CTF1 | Cardiotrophin-1 (CT-1) | 5 | UniProt NCBI |
| ZNF821 | Zinc finger protein 821 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:11 | 0.0499436884912 | 0.125 | HPS1 | BLOC-3 (biogenesis of lysosome-related organelles complex 3) |
| CORUM:241 | 0.0499436884912 | 0.125 | HPS1 | BLOC-3 (biogenesis of lysosome-related organelles complex 3) |
| CORUM:1982 | 0.0499436884912 | 0.125 | S100A6 | CACY homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TRADD | NEDD1 | 0.983 | 0.024 | hein_WMM bioplex3_WMM hein () | |
| NEDD1 | HPS1 | 0.972 | 0.114 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TRADD | S100A6 | 0.946 | 0.054 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ZNF821 | S100A6 | 0.91 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NEDD1 | S100A6 | 0.881 | 0.06 | hein_WMM bioplex3_HEK293 bioplex3_WMM hein () | |
| S100A6 | CDCA7L | 0.851 | 0.07 | hein_WMM bioplex3_HEK293 bioplex3_WMM WMM_only | |
| S100A6 | CTF1 | 0.823 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| S100A6 | DIAPH2 | 0.822 | 0.126 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ZNF821 | CDCA7L | 0.415 | bioplex3_WMM WMM_only | ||
| ZNF821 | DIAPH2 | 0.415 | bioplex3_WMM WMM_only | ||
| TRADD | ZNF821 | 0.278 | bioplex3_WMM WMM_only | ||
| ZNF821 | CTF1 | 0.278 | bioplex3_WMM WMM_only | ||
| DIAPH2 | CDCA7L | 0.274 | 0.044 | bioplex3_WMM WMM_only | |
| TRADD | CDCA7L | 0.25 | 0.058 | bioplex3_WMM WMM_only | |
| CTF1 | CDCA7L | 0.25 | bioplex3_WMM WMM_only | ||
| CTF1 | DIAPH2 | 0.113 | bioplex3_WMM WMM_only | ||
| TRADD | DIAPH2 | 0.113 | 0.078 | bioplex3_WMM WMM_only | |
| NEDD1 | CDCA7L | 0.102 | 0.036 | bioplex3_WMM WMM_only | |
| TRADD | CTF1 | 0.095 | bioplex3_WMM WMM_only | ||
| NEDD1 | CTF1 | 0.09 | bioplex3_WMM WMM_only | ||
| NEDD1 | DIAPH2 | 0.034 | 0.08 | bioplex3_WMM youn_WMM WMM_only | |
| NEDD1 | ZNF821 | 0.034 | bioplex3_WMM youn_WMM WMM_only | ||
| S100A6 | HPS1 | 0.005 | 0.08 | bioplex3_HCT116 WMM_only |
Related Complexes