hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_11224.1

Complex Portal: CPX-18039

Confidence: Medium

Genename	Protein Name	Uniprot Annotation Score	Links
OBI1	ORC ubiquitin ligase 1 (OBI1) (EC 2.3.2.27) (RING finger protein 219)	5	UniProt NCBI
CNOT3	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)	5	UniProt NCBI
BTG2	Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)	5	UniProt NCBI
CNOT8	CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)	5	UniProt NCBI
RAVER1	Ribonucleoprotein PTB-binding 1 (Protein raver-1)	4	UniProt NCBI
CNOT6L	CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) (Carbon catabolite repressor protein 4 homolog B)	5	UniProt NCBI
CNOT11	CCR4-NOT transcription complex subunit 11	5	UniProt NCBI
RIBC1	RIB43A-like with coiled-coils protein 1	5	UniProt NCBI
CNOT10	CCR4-NOT transcription complex subunit 10	5	UniProt NCBI
PABPN1L	Embryonic polyadenylate-binding protein 2 (Embryonic poly(A)-binding protein 2) (ePABP-2) (ePABP2) (Embryonic poly(A)-binding protein type II) (Poly(A)-binding protein nuclear-like 1)	3	UniProt NCBI
NANOS2	Nanos homolog 2 (NOS-2)	5	UniProt NCBI
TNKS1BP1	182 kDa tankyrase-1-binding protein	5	UniProt NCBI
FANCD2OS	FANCD2 opposite strand protein (Fanconi anemia group D2 protein opposite strand transcript protein)	1	UniProt NCBI
TOB2	Protein Tob2 (Protein Tob4) (Transducer of erbB-2 2)	5	UniProt NCBI
MMP7	Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase)	5	UniProt NCBI
TEX13A	Testis-expressed protein 13A	3	UniProt NCBI
CNOT6	CCR4-NOT transcription complex subunit 6 (EC 3.1.13.4) (CCR4 carbon catabolite repression 4-like) (Carbon catabolite repressor protein 4 homolog) (Cytoplasmic deadenylase)	5	UniProt NCBI
FHL2	Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)	5	UniProt NCBI
CNOT2	CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)	5	UniProt NCBI
CNOT9	CCR4-NOT transcription complex subunit 9 (Cell differentiation protein RQCD1 homolog) (Rcd-1)	5	UniProt NCBI
BTG3	Protein BTG3 (Abundant in neuroepithelium area protein) (BTG family member 3) (Protein Tob5)	4	UniProt NCBI
BTG1	Protein BTG1 (B-cell translocation gene 1 protein)	5	UniProt NCBI
CNOT7	CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)	5	UniProt NCBI
CNOT1	CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)	5	UniProt NCBI
GADD45B	Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118)	5	UniProt NCBI
TOB1	Protein Tob1 (Transducer of erbB-2 1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0030014	1.19684688826e-28	0.48	CNOT3 TNKS1BP1 TOB1 CNOT1 CNOT6 CNOT6L CNOT2 CNOT7 CNOT9 CNOT11 CNOT10 CNOT8	CCR4-NOT complex
REAC:R-HSA-6804115	1.5802275789e-28	0.48	CNOT3 CNOT8 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
GO:0000288	6.55527472375e-26	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289	1.38638842247e-25	0.52	CNOT3 CNOT8 TOB1 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	nuclear-transcribed mRNA poly(A) tail shortening
KEGG:03018	4.416435703e-25	0.56	CNOT3 CNOT8 TOB1 CNOT6 CNOT1 BTG3 CNOT2 BTG1 CNOT9 BTG2 CNOT10 CNOT7 TOB2 CNOT6L	RNA degradation
CORUM:7216	9.61773845486e-25	0.36	CNOT3 TNKS1BP1 CNOT1 CNOT6L CNOT2 CNOT9 CNOT11 CNOT10 CNOT8	CCR4-NOT-CNOT8-CNOT6L complex
CORUM:7215	9.61773845486e-25	0.36	CNOT3 TNKS1BP1 CNOT6 CNOT1 CNOT2 CNOT9 CNOT11 CNOT10 CNOT8	CCR4-NOT-CNOT8-CNOT6 complex
CORUM:6765	9.61773845486e-25	0.36	CNOT3 CNOT6L CNOT1 CNOT6 CNOT11 CNOT7 CNOT9 CNOT10 CNOT2	CCR4-NOT complex
CORUM:7192	9.61773845486e-25	0.36	CNOT3 TNKS1BP1 CNOT1 CNOT6 CNOT11 CNOT7 CNOT9 CNOT10 CNOT2	CCR4-NOT-CNOT7-CNOT6 complex
CORUM:7214	9.61773845486e-25	0.36	CNOT3 TNKS1BP1 CNOT1 CNOT11 CNOT7 CNOT9 CNOT10 CNOT2 CNOT6L	CCR4-NOT-CNOT7-CNOT6L complex
REAC:R-HSA-429947	2.20210895489e-23	0.44	CNOT3 TNKS1BP1 CNOT1 CNOT6 CNOT6L CNOT2 CNOT7 CNOT9 CNOT11 CNOT10 CNOT8	Deadenylation of mRNA
GO:0061157	2.64207332973e-23	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	mRNA destabilization
GO:0050779	4.5269972282e-23	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	RNA destabilization
GO:0061014	5.39409110484e-23	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of mRNA catabolic process
REAC:R-HSA-6791312	2.39434524569e-22	0.48	CNOT3 CNOT8 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	TP53 Regulates Transcription of Cell Cycle Genes
GO:0000956	1.07070113477e-21	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	nuclear-transcribed mRNA catabolic process
GO:1903313	1.8728459355e-21	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of mRNA metabolic process
GO:0043488	3.27253661074e-20	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of mRNA stability
GO:0043487	9.73338167777e-20	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of RNA stability
GO:0061013	1.47322596484e-19	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of mRNA catabolic process
REAC:R-HSA-429914	1.02716421685e-18	0.44	CNOT3 TNKS1BP1 CNOT1 CNOT6 CNOT6L CNOT2 CNOT7 CNOT9 CNOT11 CNOT10 CNOT8	Deadenylation-dependent mRNA decay
GO:0006402	1.18576604024e-17	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	mRNA catabolic process
GO:1903311	1.4546520526e-16	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of mRNA metabolic process
GO:0006401	2.55994859465e-16	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	RNA catabolic process
GO:0031331	9.35941436301e-16	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of cellular catabolic process
GO:0034655	2.52884467464e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	nucleobase-containing compound catabolic process
GO:0010608	2.94642644428e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	post-transcriptional regulation of gene expression
GO:0030015	6.54898408055e-13	0.24	CNOT3 CNOT8 CNOT1 CNOT2 CNOT7 CNOT9	CCR4-NOT core complex
GO:0046700	7.13612413407e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	heterocycle catabolic process
GO:0044270	7.39555125227e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	cellular nitrogen compound catabolic process
GO:0009896	7.94094844628e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of catabolic process
GO:0019439	8.8296125903e-13	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	aromatic compound catabolic process
GO:1901361	1.53492387439e-12	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	organic cyclic compound catabolic process
REAC:R-HSA-3700989	2.48633001508e-11	0.48	CNOT3 CNOT8 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	Transcriptional Regulation by TP53
GO:0031329	3.05041209296e-11	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of cellular catabolic process
GO:0016071	4.58330822874e-11	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	mRNA metabolic process
GO:0004535	1.11506446951e-09	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	poly(A)-specific ribonuclease activity
GO:0010629	3.26605665397e-09	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of gene expression
GO:0009894	7.60193236183e-09	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of catabolic process
CORUM:6394	1.74075664942e-07	0.12	CNOT3 CNOT1 CNOT2	CNOT1-CNOT2-CNOT3 complex
GO:0010603	3.32854782266e-07	0.16	CNOT2 CNOT6L CNOT1 CNOT6	regulation of cytoplasmic mRNA processing body assembly
GO:0010606	3.32854782266e-07	0.16	CNOT2 CNOT6L CNOT1 CNOT6	positive regulation of cytoplasmic mRNA processing body assembly
GO:0009057	5.18068706753e-07	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	macromolecule catabolic process
REAC:R-HSA-212436	7.03978863474e-07	0.52	CNOT3 CNOT8 BTG1 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	Generic Transcription Pathway
GO:0000175	1.02915357022e-06	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	3'-5'-RNA exonuclease activity
GO:0000932	1.57081766706e-06	0.28	CNOT3 CNOT8 NANOS2 CNOT1 CNOT7 CNOT9 CNOT2	P-body
REAC:R-HSA-8953854	1.72945865812e-06	0.44	CNOT3 TNKS1BP1 CNOT1 CNOT6 CNOT6L CNOT2 CNOT7 CNOT9 CNOT11 CNOT10 CNOT8	Metabolism of RNA
GO:0016896	2.0594248363e-06	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0004532	2.42014856013e-06	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	RNA exonuclease activity
REAC:R-HSA-73857	2.68540651075e-06	0.52	CNOT3 CNOT8 BTG1 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	RNA Polymerase II Transcription
GO:0051254	2.7298280108e-06	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of RNA metabolic process
GO:0044248	2.86515393157e-06	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	cellular catabolic process
GO:0010558	5.77682499179e-06	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of macromolecule biosynthetic process
GO:0031327	8.10697797394e-06	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of cellular biosynthetic process
GO:0009890	8.85579969616e-06	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of biosynthetic process
REAC:R-HSA-74160	1.22055470541e-05	0.52	CNOT3 CNOT8 BTG1 CNOT6 CNOT1 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	Gene expression (Transcription)
GO:0008408	1.2665401166e-05	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	3'-5' exonuclease activity
GO:0016796	1.4266312665e-05	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:0045935	1.79543509401e-05	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of nucleobase-containing compound metabolic process
GO:1901575	8.49169803299e-05	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	organic substance catabolic process
GO:0004527	9.50504358238e-05	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	exonuclease activity
GO:0031324	0.000121916039234	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of cellular metabolic process
GO:0140535	0.000123753092731	0.48	CNOT3 TNKS1BP1 TOB1 CNOT1 CNOT6 CNOT6L CNOT2 CNOT7 CNOT9 CNOT11 CNOT10 CNOT8	intracellular protein-containing complex
GO:0010605	0.000161353140937	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of macromolecule metabolic process
GO:0009056	0.000162636589343	0.64	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 MMP7 CNOT6L	catabolic process
GO:0060213	0.000163253573396	0.16	BTG2 TOB1 CNOT1 CNOT7	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060211	0.00023553955807	0.16	BTG2 TOB1 CNOT1 CNOT7	regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153	0.00023553955807	0.16	NANOS2 TOB1 CNOT1 CNOT7	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0065008	0.000301970618008	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	regulation of biological quality
GO:0033962	0.000448632865791	0.16	CNOT2 CNOT6L CNOT1 CNOT6	P-body assembly
GO:0009892	0.000511443106881	0.64	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	negative regulation of metabolic process
GO:0004540	0.000792158407541	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	RNA nuclease activity
GO:0019219	0.000824553343719	0.72	CNOT3 TOB1 FHL2 CNOT8 BTG1 CNOT6 OBI1 CNOT1 PABPN1L CNOT2 NANOS2 CNOT9 CNOT10 BTG2 TNKS1BP1 CNOT11 CNOT7 CNOT6L	regulation of nucleobase-containing compound metabolic process
GO:0017148	0.000840216920576	0.24	TOB1 CNOT1 NANOS2 CNOT10 CNOT9 BTG2	negative regulation of translation
GO:0048523	0.00153571980638	0.76	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 BTG3 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	negative regulation of cellular process
GO:0051252	0.00194697974505	0.68	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 CNOT6L	regulation of RNA metabolic process
GO:0036464	0.00200002297924	0.28	CNOT3 CNOT8 NANOS2 CNOT1 CNOT7 CNOT9 CNOT2	cytoplasmic ribonucleoprotein granule
GO:0034249	0.00221339013495	0.24	TOB1 CNOT1 NANOS2 CNOT10 CNOT9 BTG2	negative regulation of amide metabolic process
GO:1900151	0.00288369487019	0.16	NANOS2 TOB1 CNOT1 CNOT7	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
WP:WP4352	0.0029045480389	0.2	CNOT10 CNOT9 CNOT6L CNOT1 TNKS1BP1	Ciliary landscape
GO:0035770	0.00343838636458	0.28	CNOT3 CNOT8 NANOS2 CNOT1 CNOT7 CNOT9 CNOT2	ribonucleoprotein granule
GO:0048519	0.00529202545943	0.76	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 BTG3 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	negative regulation of biological process
GO:0051173	0.00635953194388	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of nitrogen compound metabolic process
GO:0004518	0.0116832797469	0.24	CNOT8 CNOT6 CNOT1 CNOT7 CNOT2 CNOT6L	nuclease activity
GO:0033147	0.0123105223466	0.12	CNOT2 CNOT1 CNOT9	negative regulation of intracellular estrogen receptor signaling pathway
GO:0010468	0.0136135851315	0.72	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	regulation of gene expression
GO:0003712	0.014505611329	0.32	TOB1 FHL2 CNOT6 BTG1 CNOT9 CNOT2 CNOT7 TOB2	transcription coregulator activity
WP:WP1425	0.0151764181003	0.08	TOB1 TOB2	Bone morphogenic protein signaling and regulation
GO:0010556	0.0224209371446	0.72	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	regulation of macromolecule biosynthetic process
GO:0031325	0.0224713170857	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of cellular metabolic process
GO:0031326	0.0318624519235	0.72	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	regulation of cellular biosynthetic process
GO:0010604	0.0335828690724	0.6	CNOT3 TOB1 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 CNOT6L	positive regulation of macromolecule metabolic process
GO:0009889	0.0350132766856	0.72	CNOT3 TOB1 FHL2 CNOT8 NANOS2 PABPN1L CNOT1 CNOT6 CNOT2 BTG2 CNOT9 CNOT11 TNKS1BP1 CNOT10 CNOT7 BTG1 TOB2 CNOT6L	regulation of biosynthetic process
GO:0035195	0.0392749504272	0.16	CNOT7 CNOT8 CNOT1 CNOT6	miRNA-mediated post-transcriptional gene silencing

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
CNOT3	CNOT9	1.0	0.376
CNOT3	CNOT2	1.0	0.4	mutually_exclusive (Q9UIV1)
RAVER1	CNOT6L	1.0
CNOT6L	CNOT2	1.0	0.086
CNOT11	CNOT2	1.0	0.354
CNOT6L	CNOT9	1.0	0.272
CNOT3	CNOT6L	1.0	0.058
CNOT11	CNOT9	1.0	0.68
CNOT6L	CNOT10	1.0	0.184
CNOT3	CNOT11	1.0	0.306
CNOT3	CNOT7	1.0	0.096	structurally_consistent (dimer)
CNOT8	CNOT6L	1.0	0.146
OBI1	CNOT6L	1.0	0.112
CNOT10	CNOT2	1.0	0.238
CNOT3	CNOT1	1.0	0.552
CNOT6L	BTG3	1.0	0.096	mutually_exclusive (Q9UIV1)
CNOT11	CNOT1	1.0	0.682
CNOT6L	CNOT11	1.0	0.116	structurally_consistent (dimer)
CNOT10	CNOT9	1.0	0.474
OBI1	CNOT11	1.0	0.126
CNOT3	BTG3	1.0	0.07
CNOT11	CNOT10	1.0	0.38
CNOT3	CNOT10	1.0	0.138
CNOT9	CNOT7	1.0	0.58	structurally_consistent (dimer)
TNKS1BP1	CNOT2	1.0	0.042
CNOT11	FHL2	1.0	0.036
CNOT6L	CNOT7	1.0	0.272	structurally_consistent (dimer)
CNOT6L	FHL2	1.0	0.092
CNOT3	FHL2	1.0	0.06
CNOT6L	TNKS1BP1	1.0	0.068
CNOT10	BTG3	1.0	0.036
CNOT11	TOB2	1.0	0.03
RAVER1	CNOT11	1.0
CNOT11	BTG3	1.0	0.044
CNOT10	FHL2	1.0	0.166
CNOT10	CNOT1	1.0	0.618
CNOT8	CNOT2	1.0	0.244
CNOT3	CNOT8	1.0	0.202	structurally_consistent (dimer)
CNOT9	CNOT1	1.0	0.854
CNOT8	CNOT11	1.0	0.082
FHL2	CNOT1	1.0	0.052
CNOT11	CNOT7	1.0	0.298
RAVER1	CNOT10	0.999
CNOT8	CNOT9	0.999	0.232	structurally_consistent (dimer)
CNOT6L	CNOT1	0.999	0.29
BTG3	CNOT1	0.999	0.078	structurally_consistent (Q9UIV1)
CNOT8	CNOT10	0.999	0.112
CNOT3	RAVER1	0.999
OBI1	RIBC1	0.999
CNOT10	CNOT7	0.999	0.298
CNOT2	CNOT9	0.999	0.24
CNOT7	CNOT1	0.999	0.36	structurally_consistent (dimer)
FHL2	CNOT9	0.999	0.068
CNOT2	CNOT7	0.999	0.054	structurally_consistent (dimer)
CNOT8	CNOT1	0.999	0.194
OBI1	CNOT10	0.999	0.122
CNOT3	TNKS1BP1	0.999	0.07
CNOT2	BTG3	0.999	0.038	mutually_exclusive (Q9UIV1)
RAVER1	CNOT2	0.999
BTG3	CNOT7	0.999	0.064	structurally_consistent (dimer)
CNOT9	BTG3	0.999	0.06	structurally_consistent (Q9UIV1)
OBI1	CNOT3	0.999	0.124
CNOT8	FHL2	0.999	0.056	structurally_consistent (dimer)
FHL2	CNOT2	0.999	0.062
TNKS1BP1	CNOT9	0.999	0.052
RAVER1	CNOT9	0.999
CNOT6L	TOB2	0.999	0.13	mutually_exclusive (Q9UIV1)
RAVER1	CNOT7	0.999
TNKS1BP1	BTG3	0.999	0.052
TOB2	CNOT2	0.999	0.06
FHL2	CNOT7	0.999	0.084	structurally_consistent (dimer)
CNOT11	TNKS1BP1	0.999	0.04
TNKS1BP1	FHL2	0.999	0.052
CNOT10	TNKS1BP1	0.999	0.048
CNOT2	CNOT1	0.999	0.63	structurally_consistent (Q9UIV1)
CNOT3	TOB2	0.998	0.05
CNOT8	BTG3	0.998	0.046
OBI1	CNOT7	0.998	0.124
TOB2	BTG3	0.998	0.076
CNOT10	TOB2	0.998	0.106
CNOT8	TEX13A	0.998
TEX13A	BTG3	0.998
CNOT8	CNOT7	0.998	0.086
FANCD2OS	BTG3	0.998
CNOT3	RIBC1	0.998
OBI1	CNOT2	0.997	0.086
RIBC1	BTG3	0.997
TOB2	CNOT1	0.997	0.056
OBI1	TNKS1BP1	0.997	0.068
TNKS1BP1	TOB2	0.997	0.056
OBI1	CNOT1	0.997	0.16
CNOT3	FANCD2OS	0.997
CNOT8	TNKS1BP1	0.996	0.022
RAVER1	TNKS1BP1	0.996
RAVER1	FHL2	0.996
TOB2	CNOT9	0.996	0.048
RIBC1	CNOT2	0.996
TNKS1BP1	CNOT7	0.996	0.022
TOB2	CNOT7	0.996	0.124	structurally_consistent (dimer)
CNOT7	BTG2	0.996		structurally_consistent (dimer)
FANCD2OS	CNOT7	0.996
OBI1	TOB1	0.995
OBI1	CNOT9	0.995	0.158
RIBC1	TNKS1BP1	0.995
MMP7	CNOT7	0.995		structurally_consistent (dimer)
FANCD2OS	CNOT2	0.995
RIBC1	CNOT9	0.995
CNOT8	TOB1	0.995		structurally_consistent (dimer)
RAVER1	CNOT1	0.995
TNKS1BP1	CNOT1	0.995	0.126
TEX13A	CNOT7	0.995		structurally_consistent (dimer)
MMP7	CNOT1	0.995
OBI1	BTG3	0.994	0.086
CNOT10	FANCD2OS	0.994
CNOT11	FANCD2OS	0.994
RIBC1	CNOT1	0.994
CNOT3	MMP7	0.994
NANOS2	TOB2	0.994		structurally_consistent (Q9UFF9)
FANCD2OS	CNOT9	0.994
FHL2	BTG3	0.994	0.106	mutually_exclusive (Q9UIV1)
CNOT8	RIBC1	0.994
TEX13A	CNOT9	0.994		structurally_consistent (dimer)
CNOT10	TEX13A	0.993
CNOT11	TEX13A	0.993
CNOT8	RAVER1	0.993
TNKS1BP1	MMP7	0.993
RIBC1	FHL2	0.992
CNOT8	FANCD2OS	0.992
CNOT7	PABPN1L	0.992	0.088	structurally_consistent (Q92600) structurally_consistent (dimer)
RIBC1	CNOT7	0.992
TEX13A	CNOT1	0.992		mutually_exclusive (Q9UIV1)
CNOT7	BTG1	0.992	0.062	structurally_consistent (dimer)
CNOT6L	FANCD2OS	0.992
NANOS2	BTG3	0.991
TOB2	TOB1	0.991
TNKS1BP1	FANCD2OS	0.991
OBI1	CNOT8	0.991	0.108
CNOT6L	NANOS2	0.99
CNOT11	RIBC1	0.99
CNOT3	NANOS2	0.99
CNOT6L	RIBC1	0.99
NANOS2	CNOT2	0.989
RAVER1	BTG3	0.989
RIBC1	CNOT10	0.989
FHL2	TOB1	0.988		mutually_exclusive (Q9UFF9)
FANCD2OS	CNOT1	0.988
CNOT9	TOB1	0.988		structurally_consistent (dimer)
CNOT6L	TEX13A	0.988
OBI1	FHL2	0.988	0.118
CNOT8	NANOS2	0.986		structurally_consistent (dimer)
NANOS2	CNOT7	0.985		structurally_consistent (dimer)
RAVER1	TOB1	0.984
CNOT11	NANOS2	0.984
MMP7	CNOT2	0.983
BTG3	TOB1	0.982		mutually_exclusive (Q9UIV1)
CNOT3	TOB1	0.981
CNOT10	NANOS2	0.981
CNOT6L	TOB1	0.981
OBI1	TEX13A	0.98
CNOT2	TOB1	0.979
CNOT10	TOB1	0.979
NANOS2	CNOT9	0.979
FANCD2OS	FHL2	0.975
RAVER1	TOB2	0.975
NANOS2	TNKS1BP1	0.975
NANOS2	FHL2	0.969		mutually_exclusive (Q9UFF9)
CNOT1	GADD45B	0.969
OBI1	TOB2	0.968	0.058
OBI1	FANCD2OS	0.968
CNOT1	TOB1	0.965
CNOT7	GADD45B	0.964		structurally_consistent (dimer)
NANOS2	CNOT1	0.963		mutually_exclusive (Q9UIV1)
RIBC1	TOB2	0.963
CNOT8	GADD45B	0.962
CNOT8	MMP7	0.962
CNOT10	MMP7	0.955		structurally_consistent (dimer)
CNOT6L	MMP7	0.953
CNOT3	GADD45B	0.953
CNOT7	TOB1	0.952		structurally_consistent (dimer)
CNOT11	GADD45B	0.949		structurally_consistent (Q96LI5)
TNKS1BP1	TOB1	0.942
TOB2	FHL2	0.94	0.112
CNOT9	GADD45B	0.937
CNOT1	PABPN1L	0.933	0.39	mutually_exclusive (Q9UIV1)
CNOT6L	PABPN1L	0.932	0.168	mutually_exclusive (Q9UIV1)
CNOT9	PABPN1L	0.932	0.268	structurally_consistent (Q9UIV1) structurally_consistent (dimer)
OBI1	NANOS2	0.931
CNOT11	TOB1	0.929
CNOT11	MMP7	0.913
MMP7	CNOT9	0.906
CNOT8	PABPN1L	0.894	0.056	mutually_exclusive (Q92600)
MMP7	FHL2	0.892
OBI1	RAVER1	0.886
CNOT6L	GADD45B	0.885		structurally_consistent (dimer)
CNOT10	PABPN1L	0.834	0.144	structurally_consistent (dimer)
CNOT3	PABPN1L	0.823	0.166
CNOT8	TOB2	0.82	0.052	structurally_consistent (dimer)
CNOT3	TEX13A	0.813
CNOT2	PABPN1L	0.808	0.12
FHL2	PABPN1L	0.805	0.048
CNOT2	GADD45B	0.796
CNOT10	GADD45B	0.795
TNKS1BP1	GADD45B	0.775
CNOT11	PABPN1L	0.76	0.036
RAVER1	PABPN1L	0.625
BTG2	BTG1	0.606		mutually_exclusive (Q9UIV1)
OBI1	PABPN1L	0.6	0.094
TOB1	BTG2	0.587		mutually_exclusive (Q9UIV1)
TOB1	BTG1	0.587		mutually_exclusive (Q9UIV1)
TNKS1BP1	PABPN1L	0.539	0.064
TOB2	BTG1	0.53	0.07
TOB2	BTG2	0.53		mutually_exclusive (Q9UIV1)
RAVER1	GADD45B	0.52
BTG3	PABPN1L	0.449	0.07
BTG3	BTG2	0.303		structurally_consistent (Q9UIV1)
BTG3	BTG1	0.303	0.058
TEX13A	CNOT2	0.258
CNOT6L	BTG1	0.186	0.092
CNOT6L	BTG2	0.186		structurally_consistent (Q9UIV1)
OBI1	BTG1	0.165	0.168
OBI1	BTG2	0.165
CNOT3	BTG1	0.14	0.104	mutually_exclusive (Q9UIV1)
CNOT2	BTG1	0.14	0.112	mutually_exclusive (Q9UIV1)
CNOT3	BTG2	0.14
CNOT2	BTG2	0.14
TNKS1BP1	BTG1	0.136	0.078
TNKS1BP1	BTG2	0.136
TOB2	PABPN1L	0.113	0.102
CNOT10	BTG1	0.105	0.144
CNOT11	BTG1	0.105	0.12
CNOT11	BTG2	0.105
CNOT10	BTG2	0.105
RAVER1	BTG1	0.102
RAVER1	BTG2	0.102
CNOT1	BTG1	0.091	0.146
CNOT1	BTG2	0.091		structurally_consistent (Q9UIV1)
CNOT9	BTG1	0.091	0.116
CNOT9	BTG2	0.091		structurally_consistent (Q9UIV1)
FHL2	BTG1	0.09	0.204
FHL2	BTG2	0.09
RAVER1	RIBC1	0.034
OBI1	GADD45B	0.01

Related Complexes

Genename	Complexes
OBI1	huMAP3_00551.1 huMAP3_11224.1
CNOT3	huMAP3_00551.1 huMAP3_11224.1
BTG2	huMAP3_04801.1 huMAP3_10117.1 huMAP3_11224.1 huMAP3_14234.1
CNOT8	huMAP3_00551.1 huMAP3_11224.1
RAVER1	huMAP3_00551.1 huMAP3_11224.1
CNOT6L	huMAP3_00551.1 huMAP3_11224.1
CNOT11	huMAP3_00551.1 huMAP3_11224.1
RIBC1	huMAP3_00551.1 huMAP3_11224.1 huMAP3_11343.1
CNOT10	huMAP3_00551.1 huMAP3_11224.1
PABPN1L	huMAP3_04037.1 huMAP3_04801.1 huMAP3_10117.1 huMAP3_10947.1 huMAP3_11224.1 huMAP3_12936.1 huMAP3_13132.1 huMAP3_13411.1 huMAP3_13908.1 huMAP3_15110.1
NANOS2	huMAP3_00551.1 huMAP3_11224.1
TNKS1BP1	huMAP3_00551.1 huMAP3_11224.1 huMAP3_12900.1
FANCD2OS	huMAP3_00551.1 huMAP3_05965.1 huMAP3_11224.1 huMAP3_11527.1 huMAP3_11826.1
TOB2	huMAP3_00551.1 huMAP3_11224.1
MMP7	huMAP3_00551.1 huMAP3_11224.1
TEX13A	huMAP3_00551.1 huMAP3_04879.1 huMAP3_10038.1 huMAP3_11224.1
CNOT6	huMAP3_00551.1 huMAP3_11224.1
FHL2	huMAP3_00551.1 huMAP3_01983.1 huMAP3_07638.1 huMAP3_10006.1 huMAP3_11224.1 huMAP3_13807.1
CNOT2	huMAP3_00551.1 huMAP3_11224.1
CNOT9	huMAP3_00551.1 huMAP3_11224.1 huMAP3_12900.1
BTG3	huMAP3_00551.1 huMAP3_11224.1
BTG1	huMAP3_04801.1 huMAP3_10117.1 huMAP3_11224.1 huMAP3_14234.1
CNOT7	huMAP3_00551.1 huMAP3_04801.1 huMAP3_10117.1 huMAP3_11224.1 huMAP3_14234.1
CNOT1	huMAP3_00551.1 huMAP3_11224.1
GADD45B	huMAP3_00551.1 huMAP3_06684.1 huMAP3_07720.1 huMAP3_10117.1 huMAP3_11224.1
TOB1	huMAP3_00551.1 huMAP3_11224.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_11224.1

Complex Portal: CPX-18039