hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11240.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEPD | Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase D) (Proline dipeptidase) (Prolidase) | 5 | UniProt NCBI |
| CASP3 | Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] | 5 | UniProt NCBI |
| SLC35A1 | CMP-sialic acid transporter (CMP-SA-Tr) (CMP-Sia-Tr) (CST) (Solute carrier family 35 member A1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5619037 | 0.0249718442457 | 0.5 | SLC35A1 | Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) |
| REAC:R-HSA-5663020 | 0.0249718442457 | 0.5 | SLC35A1 | Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) |
| WP:WP4873 | 0.0373151717536 | 0.5 | CASP3 | Peroxiredoxin 2 induced ovarian failure |
| REAC:R-HSA-211736 | 0.0499419797295 | 0.5 | CASP3 | Stimulation of the cell death response by PAK-2p34 |
| HP:0031156 | 0.0499436884913 | 0.5 | SLC35A1 | Decreased platelet glycoprotein Ib |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC35A1 | PEPD | 0.891 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SLC35A1 | CASP3 | 0.883 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CASP3 | PEPD | 0.009 | 0.112 | bioplex_WMM bioplex3_WMM fraction |
Related Complexes