hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11246.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IBTK | Inhibitor of Bruton tyrosine kinase (IBtk) | 5 | UniProt NCBI |
| EIF3H | Eukaryotic translation initiation factor 3 subunit H (eIF3h) (Eukaryotic translation initiation factor 3 subunit 3) (eIF-3-gamma) (eIF3 p40 subunit) | 5 | UniProt NCBI |
| EIF3I | Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36) | 5 | UniProt NCBI |
| EIF3K | Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28) | 5 | UniProt NCBI |
| JOSD1 | Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1) | 5 | UniProt NCBI |
| EIF3CL | Eukaryotic translation initiation factor 3 subunit C-like protein | 3 | UniProt NCBI |
| EIF3B | Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) | 5 | UniProt NCBI |
| EIF3C | Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110) | 5 | UniProt NCBI |
| EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220) | 5 | UniProt NCBI |
| EIF3D | Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (eIF-3-zeta) (eIF3 p66) | 5 | UniProt NCBI |
| TUSC1 | Tumor suppressor candidate gene 1 protein (TSG-9) (TSG9) | 2 | UniProt NCBI |
| EIF4A1 | Eukaryotic initiation factor 4A-I (eIF-4A-I) (eIF4A-I) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-1) | 5 | UniProt NCBI |
| EIF4A2 | Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2) | 5 | UniProt NCBI |
| PRRC2B | Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B) | 4 | UniProt NCBI |
| EIF3E | Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48) | 5 | UniProt NCBI |
| CERKL | Ceramide kinase-like protein | 5 | UniProt NCBI |
| EIF3J | Eukaryotic translation initiation factor 3 subunit J (eIF3j) (Eukaryotic translation initiation factor 3 subunit 1) (eIF-3-alpha) (eIF3 p35) | 5 | UniProt NCBI |
| EIF3A | Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) | 5 | UniProt NCBI |
| GSTA5 | Glutathione S-transferase A5 (EC 2.5.1.18) (GST class-alpha member 5) (Glutathione S-transferase A5-5) | 4 | UniProt NCBI |
| EIF3F | Eukaryotic translation initiation factor 3 subunit F (eIF3f) (Deubiquitinating enzyme eIF3f) (EC 3.4.19.12) (Eukaryotic translation initiation factor 3 subunit 5) (eIF-3-epsilon) (eIF3 p47) | 5 | UniProt NCBI |
| EIF3M | Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1) | 5 | UniProt NCBI |
| EIF4G2 | Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (Death-associated protein 5) (DAP-5) (p97) | 5 | UniProt NCBI |
| EIF3L | Eukaryotic translation initiation factor 3 subunit L (eIF3l) (Eukaryotic translation initiation factor 3 subunit 6-interacting protein) (Eukaryotic translation initiation factor 3 subunit E-interacting protein) | 5 | UniProt NCBI |
| EIF3G | Eukaryotic translation initiation factor 3 subunit G (eIF3g) (Eukaryotic translation initiation factor 3 RNA-binding subunit) (eIF-3 RNA-binding subunit) (Eukaryotic translation initiation factor 3 subunit 4) (eIF-3-delta) (eIF3 p42) (eIF3 p44) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003743 | 4.79458010866e-38 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translation initiation factor activity |
| CORUM:1097 | 3.41169217494e-37 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7, PCID1) |
| GO:0005852 | 5.08229595834e-35 | 0.583333333333 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3E EIF3I EIF3M EIF3B EIF3C EIF3CL | eukaryotic translation initiation factor 3 complex |
| CORUM:742 | 4.15174506922e-34 | 0.5 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3B EIF3C EIF3E | eIF3 complex (EIF3S6, EIF3S5, EIF3S4, EIF3S3, EIF3S6IP, EIF3S2, EIF3S9, EIF3S12, EIF3S10, EIF3S8, EIF3S1, EIF3S7) |
| GO:0008135 | 1.06934563689e-33 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translation factor activity, RNA binding |
| GO:0002183 | 2.28037698012e-33 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | cytoplasmic translational initiation |
| GO:0090079 | 5.52927863393e-32 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translation regulator activity, nucleic acid binding |
| GO:0001732 | 5.90249003628e-32 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | formation of cytoplasmic translation initiation complex |
| REAC:R-HSA-72649 | 1.15036425089e-31 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Translation initiation complex formation |
| REAC:R-HSA-72702 | 1.15036425089e-31 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Ribosomal scanning and start codon recognition |
| REAC:R-HSA-72662 | 1.56786728648e-31 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| GO:0006413 | 3.64400830447e-30 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translational initiation |
| GO:0045182 | 9.05142442414e-30 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translation regulator activity |
| REAC:R-HSA-156827 | 7.12893928458e-27 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-72706 | 8.32528121726e-27 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-72613 | 2.36820943033e-26 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Eukaryotic Translation Initiation |
| REAC:R-HSA-72737 | 2.36820943033e-26 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Cap-dependent Translation Initiation |
| WP:WP107 | 3.6959541908e-25 | 0.541666666667 | EIF3H EIF3F EIF4G1 EIF4A2 EIF3J EIF3G EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Translation factors |
| REAC:R-HSA-72695 | 2.08283357396e-24 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | Formation of the ternary complex, and subsequently, the 43S complex |
| WP:WP5027 | 6.15480104069e-24 | 0.416666666667 | EIF3H EIF3F EIF3A EIF3J EIF3G EIF3D EIF3E EIF3B EIF3C EIF3I | nsp1 from SARS CoV 2 inhibits translation initiation in the host cell |
| GO:0002181 | 2.04555609e-22 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | cytoplasmic translation |
| REAC:R-HSA-72689 | 2.25492368879e-20 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | Formation of a pool of free 40S subunits |
| REAC:R-HSA-72766 | 6.51818941233e-20 | 0.666666666667 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L EIF3D EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3E | Translation |
| GO:0006518 | 4.63589456151e-17 | 0.791666666667 | EIF3H EIF3L EIF3G EIF3F EIF4G1 GSTA5 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | peptide metabolic process |
| GO:0006412 | 5.97992114639e-17 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | translation |
| GO:0043043 | 1.01742954362e-16 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | peptide biosynthetic process |
| GO:0043604 | 2.47551771648e-15 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | amide biosynthetic process |
| GO:0043603 | 9.20880447888e-15 | 0.791666666667 | EIF3H EIF3L EIF3G EIF3F EIF4G1 GSTA5 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | amide metabolic process |
| GO:0022618 | 1.66205866425e-14 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | protein-RNA complex assembly |
| GO:0071826 | 3.11498611023e-14 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | protein-RNA complex organization |
| CORUM:4392 | 2.31953108889e-13 | 0.208333333333 | EIF3B EIF3A EIF3G EIF3I EIF3C | EIF3 complex (EIF3A, EIF3B, EIF3G, EIF3I, EIF3C) |
| CORUM:4403 | 2.31953108889e-13 | 0.208333333333 | EIF3B EIF3A EIF3G EIF3I EIF3J | EIF3 complex (EIF3A, EIF3B, EIF3G, EIF3I, EIF3J) |
| CORUM:4389 | 1.69453343699e-10 | 0.166666666667 | EIF3B EIF3G EIF3I EIF3A | EIF3 core complex (EIF3A, EIF3B, EIF3G, EIF3I) |
| GO:0022613 | 2.91764609525e-10 | 0.541666666667 | EIF3H EIF3F EIF3A EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3C EIF3E | ribonucleoprotein complex biogenesis |
| GO:1901566 | 3.41311872098e-10 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | organonitrogen compound biosynthetic process |
| GO:0075525 | 3.82722629667e-10 | 0.208333333333 | EIF3B EIF3A EIF3G EIF3L EIF3D | viral translational termination-reinitiation |
| REAC:R-HSA-392499 | 6.07655289834e-09 | 0.708333333333 | EIF3H EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF3L JOSD1 EIF3I EIF3D EIF4A1 EIF3B EIF3A EIF3C EIF3E | Metabolism of proteins |
| GO:0019081 | 1.90083797889e-08 | 0.25 | EIF3A EIF3G EIF3D EIF3B EIF3L EIF3F | viral translation |
| CORUM:4395 | 1.17907250387e-07 | 0.125 | EIF3B EIF3I EIF3G | EIF3 complex (EIF3B, EIF3G, EIF3I) |
| CORUM:4399 | 1.17907250387e-07 | 0.125 | EIF3B EIF3I EIF3J | EIF3 complex (EIF3B, EIF3J, EIF3I) |
| GO:1902415 | 1.396459195e-06 | 0.166666666667 | EIF4G1 EIF3E EIF3C EIF3D | regulation of mRNA binding |
| GO:1902416 | 1.396459195e-06 | 0.166666666667 | EIF4G1 EIF3E EIF3C EIF3D | positive regulation of mRNA binding |
| GO:1905216 | 4.18478989067e-06 | 0.166666666667 | EIF4G1 EIF3E EIF3C EIF3D | positive regulation of RNA binding |
| GO:0003676 | 1.33465986942e-05 | 0.791666666667 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B PRRC2B EIF3C EIF3CL | nucleic acid binding |
| GO:1905214 | 1.94862705925e-05 | 0.166666666667 | EIF4G1 EIF3E EIF3C EIF3D | regulation of RNA binding |
| GO:0065003 | 2.25451289439e-05 | 0.583333333333 | EIF3H EIF3F EIF4G1 EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3A EIF3C EIF3E | protein-containing complex assembly |
| GO:0006446 | 6.65462399516e-05 | 0.25 | EIF3H EIF4G1 EIF3E EIF3B EIF4A2 EIF4G2 | regulation of translational initiation |
| HPA:0600433 | 8.63852209926e-05 | 0.458333333333 | EIF4G1 EIF3F EIF3M EIF3G EIF3J EIF3CL EIF4G2 EIF3E EIF3B EIF3C EIF3I | tonsil; germinal center cells[High] |
| GO:0075522 | 9.15623696604e-05 | 0.166666666667 | EIF3B EIF3A EIF3F EIF3D | IRES-dependent viral translational initiation |
| GO:1901564 | 0.000167538507269 | 0.875 | EIF3H EIF3L EIF3G CERKL EIF4G1 GSTA5 IBTK EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF4A1 EIF3E EIF3I EIF3K EIF3B EIF3A EIF3C EIF3F EIF3CL | organonitrogen compound metabolic process |
| GO:0071541 | 0.000194546963139 | 0.125 | EIF3A EIF3I EIF3F | eukaryotic translation initiation factor 3 complex, eIF3m |
| GO:0016281 | 0.00019795084604 | 0.166666666667 | EIF4G1 EIF4A2 EIF4G2 EIF4A1 | eukaryotic translation initiation factor 4F complex |
| GO:0003723 | 0.000200600414811 | 0.583333333333 | EIF3H EIF3L EIF3G EIF4G1 EIF4A2 EIF3A EIF4G2 EIF3D EIF3I EIF4A1 EIF3B PRRC2B EIF3C EIF3E | RNA binding |
| GO:0006417 | 0.000319019501038 | 0.333333333333 | EIF3H EIF4G1 EIF4G2 EIF3D EIF3E EIF3B EIF4A2 EIF3C | regulation of translation |
| GO:0019080 | 0.00039368704222 | 0.25 | EIF3A EIF3G EIF3D EIF3B EIF3L EIF3F | viral gene expression |
| CORUM:5253 | 0.000468960518513 | 0.0833333333333 | EIF4G1 EIF4A1 | MNK1-eIF4F complex |
| GO:0034518 | 0.000502221178992 | 0.166666666667 | EIF4G1 EIF4A2 EIF4G2 EIF4A1 | RNA cap binding complex |
| GO:0097159 | 0.000588999086389 | 0.791666666667 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B PRRC2B EIF3C EIF3CL | organic cyclic compound binding |
| GO:0019538 | 0.000690698854324 | 0.791666666667 | EIF3H EIF3L EIF3G EIF3F EIF4G1 IBTK EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF4A1 EIF3E EIF3I EIF3K EIF3B EIF3A EIF3C EIF3CL | protein metabolic process |
| HPA:0530722 | 0.000818028424943 | 0.583333333333 | EIF3H EIF3G EIF4G1 EIF3M EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | spleen; cells in white pulp[>=Medium] |
| REAC:R-HSA-1169408 | 0.00112738466649 | 0.166666666667 | EIF4G1 EIF4A2 EIF4G2 EIF4A1 | ISG15 antiviral mechanism |
| GO:0034248 | 0.00116059905584 | 0.333333333333 | EIF3H EIF4G1 EIF4G2 EIF3D EIF3E EIF3B EIF4A2 EIF3C | regulation of amide metabolic process |
| HPA:0050092 | 0.00128962885573 | 0.666666666667 | EIF3H EIF3L EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3I EIF3B PRRC2B EIF3C EIF3CL | breast; myoepithelial cells[>=Medium] |
| REAC:R-HSA-1169410 | 0.00159873045582 | 0.166666666667 | EIF4G1 EIF4A2 EIF4G2 EIF4A1 | Antiviral mechanism by IFN-stimulated genes |
| GO:0043933 | 0.00180388011622 | 0.583333333333 | EIF3H EIF3F EIF4G1 EIF3K EIF3G EIF3J EIF3L EIF3D EIF3I EIF3M EIF3B EIF3A EIF3C EIF3E | protein-containing complex organization |
| REAC:R-HSA-429947 | 0.00230507164382 | 0.125 | EIF4G1 EIF4A2 EIF4A1 | Deadenylation of mRNA |
| GO:0031369 | 0.00478481888133 | 0.166666666667 | EIF4G1 EIF3F EIF3CL EIF3C | translation initiation factor binding |
| WP:WP4566 | 0.00510416576604 | 0.125 | EIF4G1 EIF4A2 EIF4A1 | Translation inhibitors in chronically activated PDGFRA cells |
| GO:0044271 | 0.00548914874572 | 0.75 | EIF3H EIF3L EIF3G EIF3F EIF4G1 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF4A1 EIF3B EIF3A EIF3C EIF3CL | cellular nitrogen compound biosynthetic process |
| GO:0010608 | 0.0066754199889 | 0.333333333333 | EIF3H EIF4G1 EIF4G2 EIF3D EIF3E EIF3B EIF4A2 EIF3C | post-transcriptional regulation of gene expression |
| GO:0005829 | 0.00692198404048 | 0.833333333333 | EIF3H EIF3L EIF3G CERKL EIF4G1 GSTA5 EIF3K EIF4A2 EIF3M EIF3J EIF4G2 JOSD1 EIF3F EIF3I EIF3D EIF4A1 EIF3B EIF3A EIF3C EIF3E | cytosol |
| HPA:0420052 | 0.00700808665524 | 0.708333333333 | EIF3H EIF3L EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | salivary gland; glandular cells[>=Medium] |
| HPA:0310433 | 0.00737016756198 | 0.333333333333 | EIF4G1 EIF3G EIF3J EIF3CL EIF4G2 EIF3E EIF3C EIF3I | lymph node; germinal center cells[High] |
| HPA:0380522 | 0.0110805507319 | 0.708333333333 | EIF3H EIF3L EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | placenta; trophoblastic cells[>=Medium] |
| HPA:0190223 | 0.0115433690762 | 0.416666666667 | EIF3H EIF3F EIF4G1 EIF3J EIF3G EIF3E EIF3I EIF3B EIF3C EIF3CL | esophagus; squamous epithelial cells[High] |
| HPA:0310442 | 0.0135405840895 | 0.625 | EIF3H EIF3F EIF4G1 EIF3M EIF3G EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | lymph node; non-germinal center cells[>=Medium] |
| HPA:0050052 | 0.0139439291361 | 0.708333333333 | EIF3H EIF3L EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | breast; glandular cells[>=Medium] |
| HPA:0470683 | 0.0145178307952 | 0.333333333333 | EIF3H EIF3G EIF4G1 EIF3J EIF3I EIF3B EIF3C EIF3CL | skin 2; epidermal cells[High] |
| HPA:0030072 | 0.015762744034 | 0.541666666667 | EIF3H EIF3G EIF4G1 EIF3M EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B EIF3A EIF3C EIF3CL | appendix; lymphoid tissue[>=Medium] |
| HPA:0600432 | 0.020998270813 | 0.625 | EIF4G1 EIF3L EIF3F PRRC2B EIF3M EIF3G EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B EIF3A EIF3C EIF3CL | tonsil; germinal center cells[>=Medium] |
| HPA:0090162 | 0.0217068329775 | 0.625 | EIF3H EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3CL EIF3B PRRC2B EIF3C EIF3E | cerebellum; Purkinje cells[>=Medium] |
| HPA:0510651 | 0.0220690725443 | 0.625 | EIF3H EIF3L EIF4G2 EIF4G1 EIF3M EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | soft tissue 2; fibroblasts[>=Low] |
| HPA:0210052 | 0.0231105122843 | 0.666666666667 | EIF3H EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | fallopian tube; glandular cells[>=Medium] |
| HPA:0350472 | 0.0239185113261 | 0.708333333333 | EIF3H EIF3L EIF4G2 EIF3F EIF4G1 EIF3M EIF3G EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | pancreas; exocrine glandular cells[>=Medium] |
| HPA:0600442 | 0.024120239564 | 0.625 | EIF3H EIF3F EIF4G1 EIF3M EIF3G EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | tonsil; non-germinal center cells[>=Medium] |
| HPA:0320102 | 0.0262981578985 | 0.666666666667 | EIF3H EIF3L EIF4G2 EIF3G EIF4G1 EIF3M EIF3A TUSC1 EIF3J EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | nasopharynx; respiratory epithelial cells[>=Medium] |
| REAC:R-HSA-429914 | 0.0288964708771 | 0.125 | EIF4G1 EIF4A2 EIF4A1 | Deadenylation-dependent mRNA decay |
| HPA:0600223 | 0.0301723297775 | 0.375 | EIF3H EIF3G EIF4G1 EIF3J EIF3D EIF3I EIF3B EIF3C EIF3CL | tonsil; squamous epithelial cells[High] |
| HPA:0460662 | 0.0353806522298 | 0.541666666667 | EIF3H EIF4G2 EIF3F EIF4G1 EIF3M EIF3G TUSC1 EIF3J EIF3D EIF3I EIF3B EIF3C EIF3CL | skin 1; keratinocytes[>=Medium] |
| HPA:0460652 | 0.0413771515773 | 0.5 | EIF3H EIF3F EIF4G1 EIF3M EIF3J EIF4G2 PRRC2B EIF3E EIF3I EIF3B EIF3C EIF3CL | skin 1; fibroblasts[>=Medium] |
| HPA:0530721 | 0.0424662048596 | 0.625 | EIF3H EIF3F EIF4G1 EIF3M EIF3G EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | spleen; cells in white pulp[>=Low] |
| WP:WP3888 | 0.0429659130037 | 0.208333333333 | EIF3H EIF4G2 EIF3F EIF3D EIF4G1 | VEGFA VEGFR2 signaling |
| HPA:0350473 | 0.0433342636052 | 0.416666666667 | EIF4G1 EIF3L EIF3F EIF3G EIF3J EIF4G2 EIF3I EIF3B EIF3C EIF3CL | pancreas; exocrine glandular cells[High] |
| HPA:0310432 | 0.0450860533445 | 0.541666666667 | EIF4G1 EIF3F PRRC2B EIF3G EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B EIF3A EIF3C EIF3CL | lymph node; germinal center cells[>=Medium] |
| HPA:0100132 | 0.0453095071352 | 0.666666666667 | EIF3H EIF3L EIF3F EIF4G1 EIF3M EIF3G EIF3A EIF3J EIF4G2 EIF3D EIF3E EIF3I EIF3B PRRC2B EIF3C EIF3CL | cerebral cortex; neuronal cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| EIF3CL | EIF3E | 1.0 | |
| EIF3B | EIF3L | 1.0 | 0.97 |
| EIF3D | EIF3CL | 1.0 | |
| EIF3D | EIF3B | 1.0 | 0.926 |
| EIF3E | EIF3B | 1.0 | 0.952 |
| EIF3D | EIF3E | 1.0 | 0.96 |
| EIF3D | EIF3F | 1.0 | 0.9 |
| EIF3C | EIF3K | 1.0 | 0.904 |
| EIF3K | EIF3L | 1.0 | 0.864 |
| EIF3C | EIF3D | 1.0 | 0.966 |
| EIF3D | EIF3L | 1.0 | 0.95 |
| EIF3K | EIF3E | 1.0 | 0.92 |
| EIF3B | EIF3G | 1.0 | 0.93 |
| EIF3F | EIF3CL | 1.0 | |
| EIF3F | EIF3E | 1.0 | 0.994 |
| EIF3F | EIF3L | 1.0 | 0.974 |
| EIF3A | EIF3B | 1.0 | 0.902 |
| EIF3I | PRRC2B | 1.0 | 0.114 |
| EIF3D | EIF3K | 1.0 | 0.942 |
| EIF3E | EIF3L | 1.0 | 0.976 |
| EIF3M | EIF3CL | 1.0 | |
| EIF3H | EIF3M | 1.0 | 0.94 |
| EIF3M | EIF3G | 1.0 | 0.894 |
| EIF3C | EIF3F | 1.0 | 0.968 |
| EIF3C | EIF3B | 1.0 | 0.978 |
| EIF3E | EIF3G | 1.0 | 0.802 |
| EIF3F | EIF3G | 1.0 | 0.944 |
| EIF3CL | EIF3L | 1.0 | |
| EIF3CL | EIF3G | 1.0 | |
| PRRC2B | EIF3L | 1.0 | 0.084 |
| EIF3F | EIF3B | 1.0 | 0.904 |
| EIF3K | EIF3F | 1.0 | 0.958 |
| EIF3D | EIF3M | 1.0 | 0.952 |
| EIF3H | EIF3CL | 1.0 | |
| EIF3I | EIF3CL | 1.0 | |
| EIF3C | EIF3E | 1.0 | 0.984 |
| EIF3K | EIF3CL | 1.0 | |
| EIF3CL | EIF3B | 1.0 | |
| EIF3H | EIF3G | 1.0 | 0.898 |
| EIF3C | EIF3A | 1.0 | 0.968 |
| EIF3K | EIF3G | 1.0 | 0.826 |
| EIF3A | EIF3K | 1.0 | 0.91 |
| EIF3C | EIF3L | 1.0 | 0.986 |
| EIF3D | EIF3G | 1.0 | 0.932 |
| EIF3A | EIF3D | 1.0 | 0.954 |
| EIF3H | PRRC2B | 1.0 | 0.186 |
| EIF3I | EIF3D | 1.0 | 0.752 |
| EIF3I | EIF3L | 1.0 | 0.844 |
| EIF3H | EIF3E | 1.0 | 0.978 |
| EIF3H | EIF3F | 1.0 | 0.978 |
| EIF3C | EIF3G | 1.0 | 0.902 |
| EIF3A | EIF3L | 1.0 | 0.984 |
| EIF3L | EIF3G | 1.0 | 0.752 |
| EIF3I | EIF3B | 1.0 | 0.978 |
| EIF3M | EIF3E | 1.0 | 0.986 |
| EIF3H | EIF3L | 1.0 | 0.968 |
| EIF3H | EIF3K | 1.0 | 0.924 |
| EIF3A | EIF3CL | 1.0 | |
| EIF3H | EIF3B | 0.999 | 0.92 |
| EIF3C | EIF3M | 0.999 | 0.93 |
| EIF3I | EIF3G | 0.999 | 0.948 |
| EIF3M | EIF3L | 0.999 | 0.928 |
| EIF3A | EIF3F | 0.999 | 0.976 |
| EIF3A | EIF3E | 0.999 | 0.96 |
| EIF3K | EIF3B | 0.999 | 0.79 |
| EIF3C | EIF3H | 0.999 | 0.97 |
| EIF3H | EIF3D | 0.999 | 0.948 |
| PRRC2B | EIF3G | 0.999 | 0.156 |
| EIF3F | EIF3M | 0.999 | 0.986 |
| EIF3I | EIF3M | 0.999 | 0.988 |
| EIF3M | EIF3B | 0.999 | 0.87 |
| EIF3A | EIF3G | 0.999 | 0.832 |
| EIF3A | EIF3I | 0.999 | 0.924 |
| PRRC2B | EIF3B | 0.999 | 0.178 |
| EIF3K | EIF3M | 0.999 | 0.938 |
| EIF3A | EIF3H | 0.999 | 0.954 |
| EIF3I | EIF3E | 0.999 | 0.896 |
| EIF3I | EIF3F | 0.999 | 0.946 |
| EIF3A | EIF3M | 0.999 | 0.892 |
| EIF3A | PRRC2B | 0.999 | 0.138 |
| PRRC2B | EIF3M | 0.999 | 0.114 |
| PRRC2B | EIF3E | 0.998 | 0.158 |
| EIF3C | EIF3CL | 0.998 | |
| EIF3D | PRRC2B | 0.998 | 0.192 |
| EIF3H | EIF3I | 0.998 | 0.914 |
| EIF4A1 | EIF4A2 | 0.997 | 0.392 |
| EIF3K | PRRC2B | 0.997 | 0.046 |
| EIF3I | EIF3K | 0.996 | 0.928 |
| EIF3C | EIF3I | 0.996 | 0.896 |
| EIF3C | PRRC2B | 0.996 | 0.058 |
| EIF3J | EIF3I | 0.995 | |
| IBTK | EIF4A1 | 0.995 | 0.227272727273 |
| EIF3J | EIF3A | 0.994 | |
| EIF3J | EIF3K | 0.994 | |
| EIF4G1 | EIF4A1 | 0.993 | |
| PRRC2B | EIF3F | 0.99 | 0.12 |
| EIF4A1 | EIF4G2 | 0.989 | 0.337529411765 |
| EIF3J | EIF3F | 0.986 | |
| EIF3H | EIF4G2 | 0.986 | 0.478 |
| IBTK | EIF3L | 0.986 | 0.256 |
| EIF3C | EIF4G2 | 0.985 | 0.714 |
| EIF4G1 | EIF3I | 0.982 | |
| EIF3J | EIF3H | 0.982 | |
| EIF3J | EIF3E | 0.981 | |
| EIF3J | EIF3M | 0.979 | |
| IBTK | EIF3E | 0.978 | 0.262 |
| EIF3B | CERKL | 0.977 | |
| EIF3J | EIF3G | 0.976 | |
| GSTA5 | EIF3F | 0.967 | |
| EIF3M | EIF4G2 | 0.966 | 0.448 |
| EIF3A | EIF4G2 | 0.966 | 0.672 |
| EIF4G2 | EIF3G | 0.965 | 0.526 |
| EIF3G | CERKL | 0.962 | |
| EIF4G1 | EIF3J | 0.961 | |
| EIF4G1 | EIF3C | 0.961 | |
| GSTA5 | EIF3M | 0.96 | |
| IBTK | EIF3G | 0.96 | 0.232 |
| EIF3J | PRRC2B | 0.958 | |
| EIF3I | CERKL | 0.957 | |
| EIF4G2 | EIF3E | 0.955 | 0.692 |
| PRRC2B | EIF3CL | 0.952 | |
| EIF3I | EIF4G2 | 0.949 | 0.292 |
| EIF3J | EIF3L | 0.947 | |
| EIF3F | JOSD1 | 0.947 | |
| EIF4A1 | EIF3J | 0.946 | |
| EIF4G2 | EIF3L | 0.946 | 0.518 |
| EIF3J | EIF4G2 | 0.943 | |
| IBTK | EIF3I | 0.941 | 0.23 |
| EIF4G1 | EIF4A2 | 0.934 | |
| EIF4G1 | EIF3E | 0.923 | |
| EIF4G2 | EIF3B | 0.923 | 0.542 |
| IBTK | EIF3A | 0.921 | 0.2 |
| PRRC2B | EIF4G2 | 0.907 | 0.134 |
| EIF3J | EIF3D | 0.902 | |
| EIF3J | EIF3B | 0.899 | |
| EIF3D | TUSC1 | 0.898 | 0.078 |
| EIF4G1 | EIF3H | 0.896 | |
| IBTK | EIF3C | 0.891 | 0.286 |
| EIF4G1 | EIF3L | 0.889 | |
| EIF3F | EIF4G2 | 0.889 | 0.48 |
| EIF3J | EIF3C | 0.886 | |
| EIF4G1 | EIF3D | 0.874 | |
| EIF4G1 | EIF3M | 0.87 | |
| EIF4A1 | EIF3G | 0.867 | 0.718 |
| EIF4G1 | PRRC2B | 0.863 | |
| EIF4G1 | EIF3G | 0.861 | |
| EIF3D | EIF4G2 | 0.857 | 0.712 |
| IBTK | EIF3F | 0.841 | 0.132 |
| EIF4G1 | EIF3F | 0.839 | |
| EIF4A1 | EIF3M | 0.83 | 0.806 |
| EIF4G1 | EIF3A | 0.828 | |
| EIF4A1 | EIF3I | 0.814 | 0.856 |
| EIF4G1 | EIF4G2 | 0.797 | |
| IBTK | EIF4A2 | 0.792 | 0.046 |
| EIF4G1 | EIF3B | 0.781 | |
| EIF4A1 | EIF3C | 0.777 | 0.81 |
| EIF4A1 | EIF3A | 0.76 | 0.784 |
| EIF4G1 | EIF3K | 0.753 | |
| EIF3K | EIF4G2 | 0.71 | 0.508 |
| EIF4A1 | EIF3F | 0.627 | 0.818 |
| EIF4A1 | EIF3D | 0.623 | 0.67 |
| EIF4A1 | EIF3B | 0.588 | 0.678 |
| EIF4A2 | EIF3M | 0.543 | 0.118 |
| IBTK | EIF3B | 0.473 | 0.206 |
| EIF4A1 | EIF3H | 0.456 | 0.798 |
| IBTK | EIF4G2 | 0.44 | 0.146 |
| EIF4A2 | EIF3K | 0.421 | 0.066 |
| EIF4A2 | EIF3L | 0.413 | 0.098 |
| IBTK | EIF3D | 0.406 | 0.128 |
| EIF3L | JOSD1 | 0.369 | |
| EIF3C | JOSD1 | 0.286 | |
| EIF4A1 | EIF3L | 0.282 | 0.648 |
| EIF3G | JOSD1 | 0.273 | |
| EIF3D | JOSD1 | 0.273 | |
| EIF4A1 | EIF3E | 0.258 | 0.838 |
| EIF4A2 | EIF3I | 0.25 | 0.47 |
| EIF3A | JOSD1 | 0.25 | |
| EIF3B | JOSD1 | 0.25 | |
| EIF4A2 | EIF3H | 0.247 | 0.0984 |
| EIF3I | JOSD1 | 0.244 | |
| EIF4A1 | EIF3K | 0.242 | 0.64 |
| EIF4A2 | EIF3G | 0.233 | 0.128 |
| EIF4A2 | EIF4G2 | 0.232 | 0.276 |
| EIF3CL | JOSD1 | 0.224 | |
| EIF3H | JOSD1 | 0.223 | |
| EIF3K | JOSD1 | 0.215 | |
| EIF3M | JOSD1 | 0.215 | |
| PRRC2B | JOSD1 | 0.215 | |
| EIF3E | JOSD1 | 0.195 | |
| IBTK | EIF3M | 0.178 | 0.172 |
| IBTK | EIF3H | 0.163 | 0.168 |
| IBTK | EIF4G1 | 0.157 | |
| EIF4A2 | EIF3A | 0.148 | 0.254 |
| EIF4A2 | EIF3D | 0.132 | 0.162 |
| EIF4A2 | EIF3E | 0.128 | 0.38416 |
| EIF3C | TUSC1 | 0.116 | 0.172 |
| EIF4G1 | EIF3CL | 0.108 | |
| EIF3A | TUSC1 | 0.104 | 0.12 |
| EIF3G | TUSC1 | 0.104 | 0.202 |
| EIF3B | TUSC1 | 0.102 | 0.118 |
| EIF3CL | TUSC1 | 0.095 | |
| EIF3H | TUSC1 | 0.089 | 0.052 |
| IBTK | EIF3J | 0.082 | |
| EIF4A2 | EIF3B | 0.079 | 0.314 |
| EIF3I | TUSC1 | 0.077 | 0.246 |
| EIF3L | TUSC1 | 0.077 | 0.08 |
| EIF3M | TUSC1 | 0.076 | 0.0535 |
| PRRC2B | TUSC1 | 0.076 | 0.07 |
| EIF3F | TUSC1 | 0.076 | 0.22 |
| EIF4G1 | TUSC1 | 0.074 | |
| IBTK | PRRC2B | 0.072 | 0.202 |
| EIF4A2 | EIF3F | 0.07 | 0.284 |
| EIF3K | TUSC1 | 0.067 | 0.066 |
| EIF3E | TUSC1 | 0.065 | 0.24 |
| EIF4A2 | EIF3C | 0.059 | 0.104 |
| IBTK | EIF3K | 0.052 | 0.142 |
| EIF4A2 | PRRC2B | 0.046 | 0.112 |
| EIF3J | EIF3CL | 0.046 | |
| EIF4A2 | EIF3J | 0.026 | |
| EIF4A1 | PRRC2B | 0.022 | 0.156 |
| IBTK | EIF3CL | 0.016 | |
| GSTA5 | EIF4G1 | 0.014 | |
| EIF4A1 | EIF3CL | 0.011 | |
| GSTA5 | EIF4A1 | 0.004 | |
| EIF3CL | EIF4G2 | 0.004 | |
| EIF4A2 | CERKL | 0.003 | |
| GSTA5 | EIF4A2 | 0.003 | |
| EIF4A1 | CERKL | 0.003 | |
| EIF4G1 | CERKL | 0.002 | |
| EIF3F | CERKL | 0.002 | |
| EIF3L | CERKL | 0.002 |
Related Complexes