hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_11259.1
Complex Portal: CPX-24542
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UQCC1 | Ubiquinol-cytochrome c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein) (bFGF-repressed Zic-binding protein) (bFZb) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog) | 5 | UniProt NCBI |
| COX20 | Cytochrome c oxidase assembly protein COX20, mitochondrial | 5 | UniProt NCBI |
| UQCC2 | Ubiquinol-cytochrome c reductase complex assembly factor 2 (Breast cancer-associated protein SGA-81M) (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19) | 5 | UniProt NCBI |
| UQCC4 | Ubiquinol-cytochrome c reductase complex assembly factor 4 (Protein CCSMST1) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0017004 | 1.37772935964e-06 | 1.0 | UQCC4 UQCC1 COX20 UQCC2 | cytochrome complex assembly |
| GO:0017062 | 6.34131776058e-05 | 0.75 | UQCC1 UQCC4 UQCC2 | respiratory chain complex III assembly |
| GO:0034551 | 6.34131776058e-05 | 0.75 | UQCC1 UQCC4 UQCC2 | mitochondrial respiratory chain complex III assembly |
| GO:0033108 | 7.35215694974e-05 | 1.0 | UQCC4 UQCC1 COX20 UQCC2 | mitochondrial respiratory chain complex assembly |
| WP:WP4921 | 0.000267833349503 | 0.5 | UQCC1 UQCC2 | Mitochondrial complex III assembly |
| GO:0007005 | 0.0242127020237 | 1.0 | UQCC4 UQCC1 COX20 UQCC2 | mitochondrion organization |
| GO:0005743 | 0.0257556797055 | 1.0 | UQCC4 UQCC1 COX20 UQCC2 | mitochondrial inner membrane |
| GO:0019866 | 0.0323627079397 | 1.0 | UQCC4 UQCC1 COX20 UQCC2 | organelle inner membrane |
| HP:0008347 | 0.049422876951 | 0.5 | UQCC2 COX20 | Decreased activity of mitochondrial complex IV |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| UQCC1 | UQCC2 | 0.999 | 0.852 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM | |
| UQCC4 | COX20 | 0.948 | 0.236 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| UQCC1 | UQCC4 | 0.892 | 0.254 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| UQCC2 | COX20 | 0.883 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UQCC1 | COX20 | 0.81 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| UQCC2 | UQCC4 | 0.653 | 0.212 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes