hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_11263.1
Confidence: Medium
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HYLS1 | Centriolar and ciliogenesis-associated protein HYLS1 (Hydrolethalus syndrome protein 1) | 5 | UniProt NCBI |
| CEP120 | Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100) | 5 | UniProt NCBI |
| DONSON | Protein downstream neighbor of Son (B17) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005736 | 1.15170860029e-06 | 1.0 | CEP120 HYLS1 DONSON | Short tibia |
| HP:0005772 | 1.99167652681e-06 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/Hypoplasia of the tibia |
| HP:0002992 | 6.33439730157e-05 | 1.0 | CEP120 HYLS1 DONSON | Abnormal tibia morphology |
| HP:0002983 | 7.11461493229e-05 | 1.0 | CEP120 HYLS1 DONSON | Micromelia |
| HP:4000059 | 0.00110338533207 | 1.0 | CEP120 HYLS1 DONSON | Abnormal lung development |
| HP:0009826 | 0.0014747204313 | 1.0 | CEP120 HYLS1 DONSON | Limb undergrowth |
| HP:0003026 | 0.00166592917139 | 1.0 | CEP120 HYLS1 DONSON | Short long bone |
| HP:0000568 | 0.0021224171016 | 1.0 | CEP120 HYLS1 DONSON | Microphthalmia |
| HP:0002981 | 0.00230958793402 | 1.0 | CEP120 HYLS1 DONSON | Abnormality of the calf |
| HP:0100887 | 0.00293644474028 | 1.0 | CEP120 HYLS1 DONSON | Abnormality of globe size |
| HP:0003826 | 0.00443651401809 | 0.666666666667 | CEP120 HYLS1 | Stillbirth |
| HP:0006493 | 0.0046849773967 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/hypoplasia involving bones of the lower limbs |
| HP:0002536 | 0.00572267550502 | 1.0 | CEP120 HYLS1 DONSON | Abnormal cortical gyration |
| HP:0040006 | 0.00944609225728 | 1.0 | CEP120 HYLS1 DONSON | Mortality/Aging |
| HP:0011420 | 0.00944609225728 | 1.0 | CEP120 HYLS1 DONSON | Age of death |
| HP:0008056 | 0.00965862232757 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/Hypoplasia affecting the eye |
| HP:0002269 | 0.0106164498774 | 1.0 | CEP120 HYLS1 DONSON | Abnormality of neuronal migration |
| HP:0004207 | 0.0117165861789 | 1.0 | CEP120 HYLS1 DONSON | Abnormal 5th finger morphology |
| WP:WP4803 | 0.0135986549013 | 0.666666666667 | CEP120 HYLS1 | Ciliopathies |
| HP:0002876 | 0.0148492820647 | 0.666666666667 | CEP120 HYLS1 | Episodic tachypnea |
| HP:0034241 | 0.0167410266547 | 0.666666666667 | CEP120 HYLS1 | Prenatal death |
| HP:0000175 | 0.0194845402877 | 1.0 | CEP120 HYLS1 DONSON | Cleft palate |
| HP:0004422 | 0.0201452261528 | 0.666666666667 | CEP120 HYLS1 | Biparietal narrowing |
| HP:0000202 | 0.024143102858 | 1.0 | CEP120 HYLS1 DONSON | Orofacial cleft |
| HP:5201015 | 0.0245396066869 | 1.0 | CEP120 HYLS1 DONSON | Craniofacial cleft |
| HP:0045060 | 0.0264474241065 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/hypoplasia involving bones of the extremities |
| HP:0001539 | 0.0270637362845 | 0.666666666667 | CEP120 HYLS1 | Omphalocele |
| HP:0009815 | 0.0332445138436 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/hypoplasia of the extremities |
| HP:0100258 | 0.0340663843581 | 0.666666666667 | CEP120 HYLS1 | Preaxial polydactyly |
| HP:0011314 | 0.0383682142819 | 1.0 | CEP120 HYLS1 DONSON | Abnormal long bone morphology |
| HP:0009824 | 0.0388502441646 | 0.666666666667 | DONSON HYLS1 | Upper limb undergrowth |
| HP:0040069 | 0.0396349906946 | 1.0 | CEP120 HYLS1 DONSON | Abnormal lower limb bone morphology |
| HP:0001162 | 0.0408514331117 | 0.666666666667 | CEP120 HYLS1 | Postaxial hand polydactyly |
| HP:0002789 | 0.0429026841472 | 0.666666666667 | CEP120 HYLS1 | Tachypnea |
| HP:0007370 | 0.0449808704429 | 1.0 | CEP120 HYLS1 DONSON | Aplasia/Hypoplasia of the corpus callosum |
| HP:0002538 | 0.0478252330498 | 1.0 | CEP120 HYLS1 DONSON | Abnormal cerebral cortex morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HYLS1 | CEP120 | 0.997 | bioplex3_WMM boldt bioplex3_HCT116 gupta () boldt_WMM WMM_only | |
| DONSON | CEP120 | 0.948 | 0.24 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| HYLS1 | huMAP3_01323.1 huMAP3_02849.1 huMAP3_11263.1 huMAP3_13878.1 |
| CEP120 | huMAP3_01323.1 huMAP3_02849.1 huMAP3_05934.1 huMAP3_11221.1 huMAP3_11263.1 |
| DONSON | huMAP3_01021.1 huMAP3_11219.1 huMAP3_11263.1 huMAP3_13726.1 |