List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_11267.1

Confidence: Medium   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
BAK1	Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7)	5	UniProt   NCBI
PMAIP1	Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa)	5	UniProt   NCBI
BBC3	Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)	5	UniProt   NCBI
BAX	Apoptosis regulator BAX (Bcl-2-like protein 4) (Bcl2-L-4)	5	UniProt   NCBI
BCL2	Apoptosis regulator Bcl-2	5	UniProt   NCBI
BCL2L1	Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)	5	UniProt   NCBI
BCL2L15	Bcl-2-like protein 15 (Bcl2-L-15) (Bcl-2 family kin) (Bfk)	4	UniProt   NCBI
TNIP3	TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein)	5	UniProt   NCBI
MIIP	Migration and invasion-inhibitory protein (IGFBP2-binding protein) (Invasion-inhibitory protein 45) (IIp45)	5	UniProt   NCBI
MCL1	Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)	5	UniProt   NCBI
BCL2L11	Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)	5	UniProt   NCBI
BCL2L10	Bcl-2-like protein 10 (Bcl2-L-10) (Anti-apoptotic protein Boo) (Anti-apoptotic protein NrH) (Apoptosis regulator Bcl-B)	5	UniProt   NCBI
BIK	Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4)	5	UniProt   NCBI
BAD	Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)	5	UniProt   NCBI
ZAR1L	Protein ZAR1-like (Zygote arrest protein 1-like)	3	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0097136	4.8028121718e-19	0.571428571429	BCL2L11 BIK PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	Bcl-2 family protein complex
WP:WP1772	1.18162593334e-18	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	Apoptosis modulation and signaling
GO:0001836	8.3944613309e-16	0.642857142857	BBC3 BCL2L11 BIK PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	release of cytochrome c from mitochondria
GO:0090199	8.72804711939e-14	0.571428571429	BCL2L11 BIK PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	regulation of release of cytochrome c from mitochondria
WP:WP254	8.91600565225e-14	0.571428571429	BBC3 BCL2L11 PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	Apoptosis
GO:0008637	2.13680988668e-13	0.642857142857	BBC3 BCL2L11 BIK PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	apoptotic mitochondrial changes
WP:WP3872	6.98045569622e-13	0.428571428571	BAK1 BCL2L10 BAX BCL2L1 MCL1 BCL2L15	Regulation of apoptosis by parathyroid hormone related protein
WP:WP4864	9.96739584112e-13	0.428571428571	BCL2L11 BAD BCL2L1 MCL1 BAX BBC3	Host pathogen interaction of human coronaviruses apoptosis
GO:0090200	1.03058449325e-12	0.5	BCL2L11 BIK PMAIP1 BAD BAK1 BAX BBC3	positive regulation of release of cytochrome c from mitochondria
KEGG:04210	2.61410410881e-12	0.571428571429	BBC3 BCL2L11 PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	Apoptosis
REAC:R-HSA-109606	4.48497871179e-12	0.5	BCL2L11 PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	Intrinsic Pathway for Apoptosis
KEGG:04215	5.80457880561e-12	0.428571428571	BCL2L11 PMAIP1 BAK1 BCL2L1 BAX BBC3	Apoptosis - multiple species
REAC:R-HSA-111453	1.27343532233e-11	0.357142857143	BAD BCL2L11 BCL2L1 PMAIP1 BBC3	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
GO:0005741	1.53258371698e-10	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	mitochondrial outer membrane
WP:WP710	2.34356896687e-10	0.5	BCL2L11 BIK PMAIP1 BAD BAK1 BAX BBC3	DNA damage response only ATM dependent
GO:0031968	3.71291864808e-10	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	organelle outer membrane
GO:0019867	3.91300364941e-10	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	outer membrane
GO:0010821	1.54260915023e-09	0.571428571429	BCL2L11 BIK PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	regulation of mitochondrion organization
KEGG:01524	1.57158065017e-09	0.428571428571	BBC3 PMAIP1 BAD BCL2L1 BAX BAK1	Platinum drug resistance
GO:0010822	2.2968547681e-09	0.5	BCL2L11 BIK PMAIP1 BAD BAK1 BAX BBC3	positive regulation of mitochondrion organization
GO:0097193	2.35433263466e-09	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	intrinsic apoptotic signaling pathway
WP:WP4216	2.5102029469e-09	0.428571428571	BCL2L11 PMAIP1 BAD BAK1 BAX BBC3	Chromosomal and microsatellite instability in colorectal cancer
KEGG:05210	3.06709055265e-09	0.428571428571	BCL2L11 PMAIP1 BAD BAK1 BAX BBC3	Colorectal cancer
GO:0097190	7.82627389327e-09	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	apoptotic signaling pathway
WP:WP3614	1.15195269037e-08	0.357142857143	BAX MCL1 BCL2L1 BAK1 PMAIP1	Photodynamic therapy induced HIF 1 survival signaling
REAC:R-HSA-109581	1.93700237271e-08	0.5	BCL2L11 PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	Apoptosis
WP:WP3611	3.96666145449e-08	0.357142857143	MCL1 BCL2L11 BCL2L1 BAK1 BAX	Photodynamic therapy induced AP 1 survival signaling
GO:2001056	4.3876298655e-08	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of cysteine-type endopeptidase activity
REAC:R-HSA-5357801	5.80717462944e-08	0.5	BCL2L11 PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	Programmed Cell Death
GO:0070059	1.16963055953e-07	0.428571428571	BCL2L11 PMAIP1 BAK1 BCL2L1 BAX BBC3	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0010950	1.24019497365e-07	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of endopeptidase activity
GO:0010952	2.10787632741e-07	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of peptidase activity
GO:0007005	5.19825526631e-07	0.642857142857	BBC3 BCL2L11 BIK PMAIP1 BAD BCL2L1 MCL1 BAX BAK1	mitochondrion organization
GO:1905897	6.00859181518e-07	0.428571428571	BCL2L11 PMAIP1 BAK1 BCL2L1 BAX BBC3	regulation of response to endoplasmic reticulum stress
GO:2000116	8.85490855303e-07	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	regulation of cysteine-type endopeptidase activity
GO:1905898	9.47973818582e-07	0.357142857143	BAX BCL2L11 BBC3 BAK1 PMAIP1	positive regulation of response to endoplasmic reticulum stress
GO:0097191	1.14198605838e-06	0.5	BAK1 BCL2L10 PMAIP1 BAD BCL2L1 MCL1 BAX	extrinsic apoptotic signaling pathway
GO:0008630	1.4128510045e-06	0.428571428571	BCL2L11 BCL2L10 BCL2L1 MCL1 BAX BAK1	intrinsic apoptotic signaling pathway in response to DNA damage
GO:1903896	1.8396911621e-06	0.285714285714	BAX BCL2L11 BAK1 BBC3	positive regulation of IRE1-mediated unfolded protein response
GO:0043280	2.75731440683e-06	0.428571428571	BCL2L11 PMAIP1 BCL2L10 BAD BAX BBC3	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
KEGG:05200	3.72963868668e-06	0.5	BCL2L11 PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	Pathways in cancer
REAC:R-HSA-114452	3.99780189739e-06	0.285714285714	BAD BCL2L11 PMAIP1 BBC3	Activation of BH3-only proteins
KEGG:05162	4.24643658062e-06	0.357142857143	BAX BAD BCL2L1 BAK1 BBC3	Measles
GO:0052548	4.61436158866e-06	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	regulation of endopeptidase activity
WP:WP4630	8.54429980424e-06	0.357142857143	BAX BAD BCL2L1 BAK1 BBC3	Measles virus infection
GO:0097192	8.8962654482e-06	0.357142857143	MCL1 BCL2L1 BAK1 BCL2L10 BAX	extrinsic apoptotic signaling pathway in absence of ligand
GO:0038034	8.8962654482e-06	0.357142857143	MCL1 BCL2L1 BAK1 BCL2L10 BAX	signal transduction in absence of ligand
GO:0052547	9.96801654745e-06	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	regulation of peptidase activity
GO:0051881	1.01992937012e-05	0.357142857143	BAX BAD BCL2L1 BAK1 PMAIP1	regulation of mitochondrial membrane potential
GO:0031966	1.20067786939e-05	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	mitochondrial membrane
GO:1900103	1.29807707416e-05	0.285714285714	BAX BCL2L11 BAK1 BBC3	positive regulation of endoplasmic reticulum unfolded protein response
GO:2001244	1.32616243401e-05	0.357142857143	BAX MCL1 BCL2L11 PMAIP1 BBC3	positive regulation of intrinsic apoptotic signaling pathway
KEGG:04115	1.80129047617e-05	0.285714285714	BAX BCL2L1 PMAIP1 BBC3	p53 signaling pathway
GO:0005740	2.14089157187e-05	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	mitochondrial envelope
GO:0042981	2.18616379893e-05	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	regulation of apoptotic process
GO:1903894	2.62212571053e-05	0.285714285714	BAX BCL2L11 BAK1 BBC3	regulation of IRE1-mediated unfolded protein response
KEGG:05212	2.90384019647e-05	0.285714285714	BAD BCL2L1 BAK1 BAX	Pancreatic cancer
GO:0043067	3.14816483636e-05	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	regulation of programmed cell death
KEGG:01521	3.24416801976e-05	0.285714285714	BAD BCL2L11 BAX BCL2L1	EGFR tyrosine kinase inhibitor resistance
KEGG:05220	3.24416801976e-05	0.285714285714	BAD BCL2L1 BAK1 BAX	Chronic myeloid leukemia
GO:0043281	3.47124412241e-05	0.428571428571	BCL2L11 PMAIP1 BCL2L10 BAD BAX BBC3	regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006919	4.13565512451e-05	0.357142857143	BAD BCL2L11 BBC3 BCL2L10 BAX	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001233	4.33089473066e-05	0.5	BBC3 BCL2L11 PMAIP1 BCL2L1 MCL1 BAX BAK1	regulation of apoptotic signaling pathway
CORUM:5823	4.44741811353e-05	0.142857142857	MCL1 BAK1	MCL1-BAK1 complex
GO:2001242	4.69081110897e-05	0.428571428571	BCL2L11 PMAIP1 BCL2L1 MCL1 BAX BBC3	regulation of intrinsic apoptotic signaling pathway
GO:0045862	5.61279325694e-05	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of proteolysis
WP:WP3982	7.83171605045e-05	0.214285714286	BAX PMAIP1 BBC3	miRNA regulation of p53 pathway in prostate cancer
WP:WP1742	7.83171605045e-05	0.214285714286	BAX PMAIP1 BBC3	TP53 network
GO:0036498	7.99814110028e-05	0.285714285714	BAX BCL2L11 BAK1 BBC3	IRE1-mediated unfolded protein response
WP:WP4806	8.85307463979e-05	0.285714285714	BAD BCL2L11 BAX BCL2L1	EGFR tyrosine kinase inhibitor resistance
WP:WP4263	9.79237142503e-05	0.285714285714	BAD BCL2L1 BAK1 BAX	Pancreatic adenocarcinoma pathway
WP:WP4925	0.00012425613553	0.214285714286	BCL2L11 PMAIP1 BBC3	Unfolded protein response
REAC:R-HSA-6803204	0.000188753156497	0.214285714286	BAX PMAIP1 BBC3	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
GO:0051345	0.000193326895166	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of hydrolase activity
GO:0006915	0.000194198679374	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	apoptotic process
GO:0034976	0.000227235535527	0.428571428571	BCL2L11 PMAIP1 BAK1 BCL2L1 BAX BBC3	response to endoplasmic reticulum stress
GO:1902235	0.000230816192231	0.285714285714	BCL2L11 BCL2L1 PMAIP1 BBC3	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0043065	0.000278941488119	0.5	BCL2L11 PMAIP1 BAD BAK1 MCL1 BAX BBC3	positive regulation of apoptotic process
GO:0012501	0.000308415790411	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	programmed cell death
GO:0008219	0.000321801034777	0.714285714286	BBC3 BCL2L11 BIK PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	cell death
GO:2001235	0.000366542378314	0.357142857143	BAX MCL1 BCL2L11 PMAIP1 BBC3	positive regulation of apoptotic signaling pathway
GO:0043068	0.000378495976416	0.5	BCL2L11 PMAIP1 BAD BAK1 MCL1 BAX BBC3	positive regulation of programmed cell death
GO:1900101	0.000389049485032	0.285714285714	BAX BCL2L11 BAK1 BBC3	regulation of endoplasmic reticulum unfolded protein response
WP:WP2447	0.00043749427219	0.214285714286	BAD BAX BCL2L1	Amyotrophic lateral sclerosis ALS
KEGG:05225	0.000689829158948	0.285714285714	BAD BCL2L1 BAK1 BAX	Hepatocellular carcinoma
GO:0051400	0.000698569295426	0.214285714286	MCL1 BAX BCL2L1	BH domain binding
GO:0051434	0.000698569295426	0.214285714286	MCL1 BAX BCL2L1	BH3 domain binding
WP:WP1971	0.000789109146928	0.214285714286	BAD BBC3 BAX	Integrated cancer pathway
WP:WP4396	0.000801533892887	0.285714285714	BAX BCL2L11 BAK1 BBC3	Nonalcoholic fatty liver disease
KEGG:05213	0.000836612996345	0.214285714286	BAD BAK1 BAX	Endometrial cancer
GO:0031975	0.00114364632828	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	envelope
GO:0031967	0.00114364632828	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	organelle envelope
GO:0046902	0.00120157929621	0.285714285714	BAD BCL2L1 BAK1 PMAIP1	regulation of mitochondrial membrane permeability
KEGG:05203	0.00127984658053	0.285714285714	BAX BAD BAK1 PMAIP1	Viral carcinogenesis
GO:0010638	0.0013813287093	0.5	BCL2L11 BIK PMAIP1 BAD BAK1 BAX BBC3	positive regulation of organelle organization
KEGG:05218	0.00142363582364	0.214285714286	BAD BAK1 BAX	Melanoma
KEGG:05170	0.00147970242596	0.285714285714	BAD BCL2L1 BAK1 BAX	Human immunodeficiency virus 1 infection
REAC:R-HSA-5633008	0.00162571658561	0.214285714286	BAX PMAIP1 BBC3	TP53 Regulates Transcription of Cell Death Genes
KEGG:05223	0.00188009856862	0.214285714286	BAD BAK1 BAX	Non-small cell lung cancer
GO:1902237	0.00195378579303	0.214285714286	BCL2L11 PMAIP1 BBC3	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
WP:WP4155	0.00231463028131	0.214285714286	BAD BAK1 BAX	Endometrial cancer
GO:0030162	0.00236959046776	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	regulation of proteolysis
REAC:R-HSA-111457	0.00238968144039	0.142857142857	BAK1 BAX	Release of apoptotic factors from the mitochondria
WP:WP4685	0.0027024073326	0.214285714286	BAD BAK1 BAX	Melanoma
GO:0070513	0.00292902387419	0.214285714286	MCL1 BAX BCL2L1	death domain binding
WP:WP3303	0.00313072620973	0.214285714286	TNIP3 BAX BAD	RAC1 PAK1 p38 MMP2 pathway
KEGG:01522	0.00329612652804	0.214285714286	BIK BAX BAD	Endocrine resistance
WP:WP1530	0.00343974183373	0.214285714286	BAX PMAIP1 BBC3	miRNA regulation of DNA damage response
WP:WP707	0.00343974183373	0.214285714286	BAX PMAIP1 BBC3	DNA damage response
GO:0090559	0.00349800823415	0.285714285714	BAD BCL2L1 BAK1 PMAIP1	regulation of membrane permeability
GO:0006974	0.00376727308001	0.571428571429	BBC3 BCL2L11 PMAIP1 BCL2L10 BCL2L1 MCL1 BAX BAK1	DNA damage response
WP:WP4255	0.00376819179791	0.214285714286	BAD BAK1 BAX	Non small cell lung cancer
KEGG:05222	0.00380039958933	0.214285714286	BCL2L1 BAK1 BAX	Small cell lung cancer
GO:0051336	0.00459525058211	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	regulation of hydrolase activity
WP:WP4963	0.00665832680083	0.214285714286	BAX PMAIP1 BBC3	p53 transcriptional gene network
KEGG:04151	0.0068477500831	0.285714285714	BAD MCL1 BCL2L1 BCL2L11	PI3K-Akt signaling pathway
WP:WP231	0.00742330742014	0.214285714286	BAD BAX BCL2L1	TNF alpha signaling pathway
GO:0031334	0.00835594241458	0.357142857143	BAX BIK BCL2L11 BAK1 BBC3	positive regulation of protein-containing complex assembly
WP:WP4658	0.00882246767259	0.214285714286	BCL2L1 BAK1 BAX	Small cell lung cancer
GO:0030968	0.0101062235466	0.285714285714	BAX BCL2L11 BAK1 BBC3	endoplasmic reticulum unfolded protein response
WP:WP4172	0.0116507975031	0.285714285714	BAD MCL1 BCL2L1 BCL2L11	PI3K Akt signaling pathway
KEGG:05160	0.0132550197928	0.214285714286	BAD BAK1 BAX	Hepatitis C
WP:WP3657	0.0168255726916	0.142857142857	MCL1 BCL2L1	Hematopoietic stem cell gene regulation by GABP alpha beta complex
WP:WP2507	0.0168255726916	0.142857142857	BAK1 BAX	Nanomaterial induced apoptosis
KEGG:05168	0.0178360232126	0.285714285714	BAD BCL2L1 BAK1 BAX	Herpes simplex virus 1 infection
GO:0046982	0.0179282614957	0.357142857143	MCL1 BCL2L1 BAK1 BCL2L10 BAX	protein heterodimerization activity
KEGG:05206	0.0189814300125	0.214285714286	MCL1 BAK1 BCL2L11	MicroRNAs in cancer
GO:0005739	0.0198191820579	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	mitochondrion
GO:0033554	0.0210491353845	0.642857142857	BBC3 BCL2L11 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	cellular response to stress
GO:0033043	0.021220355382	0.571428571429	BCL2L11 BIK PMAIP1 BAD BAK1 BCL2L1 BAX BBC3	regulation of organelle organization
GO:0043085	0.0215812009411	0.5	BCL2L11 BCL2L10 PMAIP1 BAD BAK1 BAX BBC3	positive regulation of catalytic activity
KEGG:05202	0.021738009856	0.214285714286	BCL2L1 BAK1 BAX	Transcriptional misregulation in cancer
GO:0034620	0.0219728476214	0.285714285714	BAX BCL2L11 BAK1 BBC3	cellular response to unfolded protein
GO:0035556	0.0253207298394	0.714285714286	BBC3 BCL2L11 TNIP3 PMAIP1 BCL2L10 BAD BCL2L1 MCL1 BAX BAK1	intracellular signal transduction
KEGG:05216	0.0261257249417	0.142857142857	BAK1 BAX	Thyroid cancer
KEGG:05022	0.0281917287101	0.285714285714	BAD BCL2L1 BAK1 BAX	Pathways of neurodegeneration - multiple diseases
REAC:R-HSA-9614657	0.0285039839386	0.142857142857	BBC3 BCL2L11	FOXO-mediated transcription of cell death genes
WP:WP3613	0.0294217529211	0.142857142857	BBC3 BCL2L11	Photodynamic therapy induced unfolded protein response
WP:WP4838	0.0318561232025	0.142857142857	BAK1 BAX	Regucalcin in proximal tubule epithelial kidney cells
REAC:R-HSA-111471	0.0322868340515	0.142857142857	BAK1 BAX	Apoptotic factor-mediated response
KEGG:05417	0.0336568278998	0.214285714286	BAD BAX BCL2L1	Lipid and atherosclerosis
KEGG:05169	0.0336568278998	0.214285714286	BCL2L11 BAK1 BAX	Epstein-Barr virus infection
WP:WP5087	0.039355014475	0.285714285714	BAX MCL1 BAK1 BBC3	Pleural mesothelioma
GO:0032469	0.0395048083263	0.214285714286	BAX BAK1 BBC3	endoplasmic reticulum calcium ion homeostasis
GO:0035967	0.0399566756791	0.285714285714	BAX BCL2L11 BAK1 BBC3	cellular response to topologically incorrect protein
GO:0097145	0.0426062655276	0.142857142857	BAK1 BAX	BAK complex
GO:0042391	0.043422212207	0.357142857143	BAX BAD BCL2L1 BAK1 PMAIP1	regulation of membrane potential
GO:0080135	0.0475905583284	0.428571428571	BCL2L11 PMAIP1 BAK1 BCL2L1 BAX BBC3	regulation of cellular response to stress
CORUM:2000	0.0499958217778	0.0714285714286	BAX	BAX homo-oligomer complex
CORUM:3492	0.0499958217778	0.0714285714286	BAX	BAX homo-oligomer complex



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
MCL1	BCL2L11	1.0	0.162
BCL2L1	BAX	1.0
BCL2L1	BAD	0.999	0.078
MCL1	PMAIP1	0.999	0.108
BCL2L11	BCL2	0.999	0.16
BCL2L1	BCL2L11	0.998	0.208
BCL2L1	BCL2	0.998	0.168
BAX	BCL2	0.998
MCL1	BAK1	0.998	0.132
BAD	BCL2	0.998	0.146
MCL1	BAX	0.997
TNIP3	BCL2	0.997
MCL1	BBC3	0.997
BCL2L11	BAX	0.993
BBC3	BCL2	0.991
BCL2L1	BBC3	0.988
MIIP	BAD	0.987
BAX	BAK1	0.987
BCL2L1	BIK	0.984
BCL2L1	BAK1	0.982	0.0706666666667
BIK	BCL2	0.982
BCL2L1	BCL2L15	0.975
BBC3	BAX	0.966
BBC3	BAK1	0.959
BCL2L15	BAX	0.959
BCL2L11	BBC3	0.956
BCL2L11	BAK1	0.947	0.094
BCL2L11	ZAR1L	0.936
BCL2L1	ZAR1L	0.929
BCL2L1	MCL1	0.92	0.056
PMAIP1	BAK1	0.912	0.09
BCL2L10	BCL2L11	0.881
BCL2L11	BAD	0.865	0.09
TNIP3	BBC3	0.86
PMAIP1	BBC3	0.858
BCL2L10	BAX	0.846
BAX	BAD	0.845
MCL1	ZAR1L	0.83
BBC3	BAD	0.795
TNIP3	BAX	0.786
TNIP3	BAD	0.768
PMAIP1	BCL2L11	0.741	0.104
BIK	BAK1	0.698
PMAIP1	BAX	0.675
TNIP3	BCL2L11	0.651
BIK	BAD	0.633
BIK	BCL2L11	0.616
TNIP3	BIK	0.616
BIK	BBC3	0.455
BIK	BAX	0.437
BAK1	BAD	0.427	0.07
BCL2L1	TNIP3	0.396
MCL1	BCL2	0.25	0.23
BAK1	BCL2	0.146	0.1





Related Complexes

Genename	Complexes
BAK1	huMAP3_03350.1 huMAP3_07554.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11267.1
PMAIP1	huMAP3_02086.1 huMAP3_10695.1 huMAP3_11267.1
BBC3	huMAP3_03350.1 huMAP3_07554.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11267.1
BAX	huMAP3_03350.1 huMAP3_07554.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11241.1 huMAP3_11267.1
BCL2	huMAP3_08709.1 huMAP3_10695.1 huMAP3_11267.1
BCL2L1	huMAP3_00428.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11267.1
BCL2L15	huMAP3_00428.1 huMAP3_07554.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11241.1 huMAP3_11267.1
TNIP3	huMAP3_01845.1 huMAP3_08709.1 huMAP3_10845.1 huMAP3_11267.1
MIIP	huMAP3_00914.1 huMAP3_11267.1 huMAP3_13356.1 huMAP3_14718.1
MCL1	huMAP3_02086.1 huMAP3_10695.1 huMAP3_11267.1
BCL2L11	huMAP3_03350.1 huMAP3_04180.1 huMAP3_07554.1 huMAP3_08181.1 huMAP3_10156.1 huMAP3_10695.1 huMAP3_11267.1
BCL2L10	huMAP3_02482.1 huMAP3_11241.1 huMAP3_11267.1 huMAP3_13337.1 huMAP3_14117.1 huMAP3_14321.1 huMAP3_14768.1 huMAP3_14963.1 huMAP3_15320.1
BIK	huMAP3_01845.1 huMAP3_08181.1 huMAP3_10695.1 huMAP3_11267.1
BAD	huMAP3_04537.1 huMAP3_07596.1 huMAP3_07838.1 huMAP3_09810.1 huMAP3_10808.1 huMAP3_11267.1 huMAP3_12897.1 huMAP3_13356.1
ZAR1L	huMAP3_11267.1 huMAP3_12983.1